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Volumn 111, Issue 4, 2011, Pages 1218-1224

Metabolic disruptions induced by reduced ambulatory activity in free-living humans

Author keywords

Inactivity; Insulin sensitivity; Obesity; Skeletal muscle

Indexed keywords

ANIMAL; BED REST; EXERCISE; HUMAN; INSULIN RESISTANCE; LIFESTYLE; METABOLIC DISORDER; METABOLISM; OBESITY; PHYSIOLOGY; REVIEW;

EID: 80054703301     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00478.2011     Document Type: Review
Times cited : (68)

References (48)
  • 2
    • 24044520360 scopus 로고    scopus 로고
    • Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease
    • DOI 10.1152/japplphysiol.00160.2005
    • Bassuk SS, Manson JE. Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease. J Appl Physiol 99: 1193-1204, 2005. (Pubitemid 41214540)
    • (2005) Journal of Applied Physiology , vol.99 , Issue.3 , pp. 1193-1204
    • Bassuk, S.S.1    Manson, J.E.2
  • 3
    • 0025748673 scopus 로고
    • Metabolic implications of body fat distribution
    • Bjorntorp P. Metabolic implications of body fat distribution. Diabetes Care 14: 1132-1143, 1991.
    • (1991) Diabetes Care , vol.14 , pp. 1132-1143
    • Bjorntorp, P.1
  • 5
    • 45549108083 scopus 로고    scopus 로고
    • Reduced physical activity and risk of chronic disease: The biology behind the consequences
    • Booth FW, Laye MJ, Lees SJ, Rector RS, Thyfault JP. Reduced physical activity and risk of chronic disease: The biology behind the consequences. Eur J Appl Physiol 102: 381-390, 2008.
    • (2008) Eur J Appl Physiol , vol.102 , pp. 381-390
    • Booth, F.W.1    Laye, M.J.2    Lees, S.J.3    Rector, R.S.4    Thyfault, J.P.5
  • 7
    • 0021799805 scopus 로고
    • Acute reversal of the enhanced insulin action in trained athletes. Association with insulin receptor changes
    • Burstein R, Polychronakos C, Toews CJ, MacDougall JD, Guyda HJ, Posner BI. Acute reversal of the enhanced insulin action in trained athletes. Association with insulin receptor changes. Diabetes 34: 756-760, 1985. (Pubitemid 15018658)
    • (1985) Diabetes , vol.34 , Issue.8 , pp. 756-760
    • Burstein, R.1    Polychronakos, C.2    Toews, C.J.3
  • 8
    • 0347993116 scopus 로고    scopus 로고
    • Eating, exercise, and "thrifty" genotypes: Connecting the dots toward an evolutionary understanding of modern chronic diseases
    • DOI 10.1152/japplphysiol.00757.2003
    • Chakravarthy MV, Booth FW. Eating, exercise, and "thrifty" genotypes: Connecting the dots toward an evolutionary understanding of modern chronic diseases. J Appl Physiol 96: 3-10, 2004. (Pubitemid 38035170)
    • (2004) Journal of Applied Physiology , vol.96 , Issue.1 , pp. 3-10
    • Chakravarthy, M.V.1    Booth, F.W.2
  • 9
    • 34249939788 scopus 로고    scopus 로고
    • Cardiovascular disease under the influence of excess visceral fat
    • Despres JP. Cardiovascular disease under the influence of excess visceral fat. Crit Pathw Cardiol 6: 51-59, 2007.
    • (2007) Crit Pathw Cardiol , vol.6 , pp. 51-59
    • Despres, J.P.1
  • 11
    • 0016795518 scopus 로고
    • Skeletal muscle respiratory capacity, endurance, and glycogen utilization
    • Fitts RH, Booth FW, Winder WW, Holloszy JO. Skeletal muscle respiratory capacity, endurance, and glycogen utilization. Am J Physiol 228: 1029-1033, 1975.
    • (1975) Am J Physiol , vol.228 , pp. 1029-1033
    • Fitts, R.H.1    Booth, F.W.2    Winder, W.W.3    Holloszy, J.O.4
  • 13
    • 0034033372 scopus 로고    scopus 로고
    • Visceral fat and insulin resistance - Causative or correlative?
    • Frayn KN. Visceral fat and insulin resistance- causative or correlative? Br J Nutr 83, Suppl 1: S71-S77, 2000. (Pubitemid 30319085)
    • (2000) British Journal of Nutrition , vol.83 , Issue.SUPPL. 1
    • Frayn, K.N.1
  • 14
    • 0033431902 scopus 로고    scopus 로고
    • Prospective cohort study of the relationship of markers of insulin resistance and secretion with weight gain and changes in regional adiposity
    • Gould AJ, Williams DE, Byrne CD, Hales CN, Wareham NJ. Prospective cohort study of the relationship of markers of insulin resistance and secretion with weight gain and changes in regional adiposity. Int J Obes Relat Metab Disord 23: 1256-1261, 1999. (Pubitemid 30011950)
    • (1999) International Journal of Obesity , vol.23 , Issue.12 , pp. 1256-1261
    • Gould, A.J.1    Williams, D.E.M.2    Byrne, C.D.3    Hales, C.N.4    Wareham, N.J.5
  • 15
    • 4644235275 scopus 로고    scopus 로고
    • Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance
    • DOI 10.1002/dmrr.505
    • Hawley JA. Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance. Diabetes Metab Res Rev 20: 383-393, 2004. (Pubitemid 39302963)
    • (2004) Diabetes/Metabolism Research and Reviews , vol.20 , Issue.5 , pp. 383-393
    • Hawley, J.A.1
  • 17
    • 0036021855 scopus 로고    scopus 로고
    • Invited review: Effects of acute exercise and exercise training on insulin resistance
    • Henriksen EJ. Effects of acute exercise and exercise training on insulin resistance. J Appl Physiol 93: 788-796, 2002. (Pubitemid 34810247)
    • (2002) Journal of Applied Physiology , vol.93 , Issue.2 , pp. 788-796
    • Henriksen, E.J.1
  • 18
    • 78049316845 scopus 로고    scopus 로고
    • Impact of physical inactivity on subcutaneous adipose tissue metabolism in healthy young male offspring of patients with type 2 diabetes
    • Hojbjerre L, Sonne MP, Alibegovic AC, Dela F, Vaag A, Meldgaard JB, Christensen KB, Stallknecht B. Impact of physical inactivity on subcutaneous adipose tissue metabolism in healthy young male offspring of patients with type 2 diabetes. Diabetes 59: 2790 - 2798, 2010.
    • (2010) Diabetes , vol.59 , Issue.2790-2798
    • Hojbjerre, L.1    Sonne, M.P.2    Alibegovic, A.C.3    Dela, F.4    Vaag, A.5    Meldgaard, J.B.6    Christensen, K.B.7    Stallknecht, B.8
  • 19
    • 21644473127 scopus 로고    scopus 로고
    • Invited review: Exercise-induced increase in muscle insulin sensitivity
    • DOI 10.1152/japplphysiol.00123.2005
    • Holloszy JO. Exercise-induced increase in muscle insulin sensitivity. J Appl Physiol 99: 338-343, 2005. (Pubitemid 40934500)
    • (2005) Journal of Applied Physiology , vol.99 , Issue.1 , pp. 338-343
    • Holloszy, J.O.1
  • 22
    • 2942735492 scopus 로고    scopus 로고
    • The molecular mechanism linking muscle fat accumulation to insulin resistance
    • DOI 10.1079/PNS2004351
    • Hulver MW, Lynis Dohm G. The molecular mechanism linking muscle fat accumulation to insulin resistance. Proc Nutr Soc 63: 375-380, 2004. (Pubitemid 38787493)
    • (2004) Proceedings of the Nutrition Society , vol.63 , Issue.2 , pp. 375-380
    • Hulver, M.W.1    Dohm, G.L.2
  • 23
    • 78049317761 scopus 로고    scopus 로고
    • Physical activity, sedentary behavior, and health: Paradigm paralysis or paradigm shift?
    • Katzmarzyk PT. Physical activity, sedentary behavior, and health: Paradigm paralysis or paradigm shift? Diabetes 59: 2717-2725, 2010.
    • (2010) Diabetes , vol.59 , Issue.2717-2725
    • Katzmarzyk, P.T.1
  • 24
    • 0034727692 scopus 로고    scopus 로고
    • The economic burden of physical inactivity in Canada
    • Katzmarzyk PT, Gledhill N, Shephard RJ. The economic burden of physical inactivity in Canada. CMAJ 163: 1435-1440, 2000.
    • (2000) CMA.J. , vol.163 , pp. 1435-1440
    • Katzmarzyk, P.T.1    Gledhill, N.2    Shephard, R.J.3
  • 27
    • 13844281624 scopus 로고    scopus 로고
    • Alterations in insulin receptor signalling in the rat epitrochlearis muscle upon cessation of voluntary exercise
    • DOI 10.1113/jphysiol.2004.073593
    • Kump DS, Booth FW. Alterations in insulin receptor signalling in the rat epitrochlearis muscle upon cessation of voluntary exercise. J Physiol 562: 829-838, 2005. (Pubitemid 40246796)
    • (2005) Journal of Physiology , vol.562 , Issue.3 , pp. 829-838
    • Kump, D.S.1    Booth, F.W.2
  • 28
    • 21344445082 scopus 로고    scopus 로고
    • Sustained rise in triacylglycerol synthesis and increased epididymal fat mass when rats cease voluntary wheel running
    • DOI 10.1113/jphysiol.2005.084525
    • Kump DS, Booth FW. Sustained rise in triacylglycerol synthesis and increased epididymal fat mass when rats cease voluntary wheel running. J Physiol 565: 911-925, 2005. (Pubitemid 40908869)
    • (2005) Journal of Physiology , vol.565 , Issue.3 , pp. 911-925
    • Kump, D.S.1    Booth, F.W.2
  • 31
    • 24144441285 scopus 로고    scopus 로고
    • Point: Visceral adiposity is causally related to insulin resistance
    • DOI 10.2337/diacare.28.9.2322
    • Lebovitz HE, Banerji MA. Point: Visceral adiposity is causally related to insulin resistance. Diabetes Care 28: 2322-2325, 2005. (Pubitemid 41242490)
    • (2005) Diabetes Care , vol.28 , Issue.9 , pp. 2322-2325
    • Lebovitz, H.E.1    Banerji, M.A.2
  • 34
    • 24144473122 scopus 로고    scopus 로고
    • Counterpoint: Visceral adiposity is not causally related to insulin resistance
    • DOI 10.2337/diacare.28.9.2326
    • Miles JM, Jensen MD. Counterpoint: Visceral adiposity is not causally related to insulin resistance. Diabetes Care 28: 2326-2328, 2005. (Pubitemid 41242491)
    • (2005) Diabetes Care , vol.28 , Issue.9 , pp. 2326-2328
    • Miles, J.M.1    Jensen, M.D.2
  • 35
    • 33845542745 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
    • DOI 10.2337/db06-S002
    • Morino K, Petersen KF, Shulman GI. Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes 55, Suppl 2: S9-S15, 2006. (Pubitemid 44927027)
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 2
    • Morino, K.1    Petersen, K.F.2    Shulman, G.I.3
  • 37
    • 70349566593 scopus 로고
    • Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
    • Neel JV. Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet 14: 353-362, 1962.
    • (1962) Am J Hum Genet , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 45
    • 0038199726 scopus 로고    scopus 로고
    • PTP1B: From the sidelines to the front lines!
    • DOI 10.1016/S0014-5793(03)00603-3
    • Tonks NK. PTP1B: From the sidelines to the front lines! FEBS Lett 546: 140-148, 2003. (Pubitemid 36782295)
    • (2003) FEBS Letters , vol.546 , Issue.1 , pp. 140-148
    • Tonks, N.K.1
  • 46
  • 47
    • 2342466734 scopus 로고    scopus 로고
    • Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
    • DOI 10.2337/diacare.27.5.1047
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 27: 1047-1053, 2004. (Pubitemid 38579764)
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 48
    • 8744259926 scopus 로고    scopus 로고
    • Uncoupling insulin signalling by serine/threonine phosphorylation: A molecular basis for insulin resistance
    • DOI 10.1042/BST0320812
    • Zick Y. Uncoupling insulin signalling by serine/threonine phosphorylation: A molecular basis for insulin resistance. Biochem Soc Trans 32: 812-816, 2004. (Pubitemid 39524386)
    • (2004) Biochemical Society Transactions , vol.32 , Issue.5 , pp. 812-816
    • Zick, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.