A 5-fluorouracil-loaded pH-responsive dendrimer nanocarrier for tumor targeting

International Journal of Pharmaceutics

Volumn 420, Issue 2, 2011, Pages 378-384

  Jin, Yiguang ^a,b   Ren, Xia ^a,b   Wang, Wei ^b   Ke, Lijing ^c,d   Ning, Erjuan ^a,b   Du, Lina ^a   Bradshaw, Jeremy ^c  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b HENAN UNIVERSITY   (China)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d FUZHOU UNIVERSITY   (China)

Author keywords

5 Fluorouracil; Nanocarriers; pH responsive; Poly(amidoamine); Tumor targeting

Indexed keywords

DENDRIMER; FLUOROURACIL; MACROGOL; NANOCARRIER; POLY[2 (N,N DIETHYLAMINO)ETHYL METHACRYLATE]; POLY[2 (N,N DIETHYLAMINO)ETHYL METHACRYLATE]METHOXY POLY(ETHYLENE GLYCOL); POLYAMIDOAMINE; POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SIZE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG LIVER LEVEL; FEMALE; HEPATOMA CELL; HYDROPHILICITY; HYDROPHOBICITY; LUNG; MOLECULARLY TARGETED THERAPY; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; SPLEEN; ZETA POTENTIAL;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE, TUMOR; DENDRIMERS; DRUG CARRIERS; FEMALE; FLUOROURACIL; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIVER NEOPLASMS, EXPERIMENTAL; METHACRYLATES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NYLONS; POLYETHYLENE GLYCOLS; TISSUE DISTRIBUTION; TUMOR BURDEN;

EID: 80054691692     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.053     Document Type: Article

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