Enhanced cellular delivery of idarubicin by surface modification of propyl starch nanoparticles employing pteroic acid conjugated polyvinyl alcohol

International Journal of Pharmaceutics

Volumn 420, Issue 1, 2011, Pages 147-155

  Jain, Ratnesh ^a,b   Dandekar, Prajakta ^a,b   Loretz, Brigitta ^a,b   Melero, Ana ^b   Stauner, Thomas ^a   Wenz, Gerhard ^a   Koch, Marcus ^a   Lehr, Claus Michael ^a,b  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Cellular uptake; Confocal scanning laser microscopy; Cytotoxicity; Idarubicin; Nanoparticles; Protein adsorption

Indexed keywords

AMINO ACID; IDARUBICIN; NANOPARTICLE; POLYVINYL ALCOHOL; PTEROIC ACID; STARCH; UNCLASSIFIED DRUG;

ARTICLE; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; DIFFUSION; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PROTEIN BINDING; DRUG RELEASE; EMULSION; INTERNALIZATION; NANOENCAPSULATION; PRIORITY JOURNAL; SURFACE PROPERTY;

ADENOCARCINOMA; ADSORPTION; ANTIBIOTICS, ANTINEOPLASTIC; CACO-2 CELLS; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; HT29 CELLS; HUMANS; IDARUBICIN; KINETICS; LUNG NEOPLASMS; MICROSCOPY, CONFOCAL; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; POLYVINYL ALCOHOL; PROTEIN BINDING; PTERINS; SOLUBILITY; STARCH; SURFACE-ACTIVE AGENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 80054690663     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.030     Document Type: Article

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