-
1
-
-
0026464583
-
Fasting insulin in relation to subsequent blood pressure changes and hypertension in women
-
Lissner L, Bengtsson C, Lapidus L, Kristjansson K, Wedel H. Fasting insulin in relation to subsequent blood pressure changes and hypertension in women. Hypertension 1992;20:797-801
-
(1992)
Hypertension
, vol.20
, pp. 797-801
-
-
Lissner, L.1
Bengtsson, C.2
Lapidus, L.3
Kristjansson, K.4
Wedel, H.5
-
2
-
-
0029111790
-
The role of insulin in clustering of serum lipids and blood pressure in children and adolescents. The Cardiovascular Risk in Young Finns Study
-
Raitakari OT, Porkka KV, Rönnemaa T, et al. The role of insulin in clustering of serum lipids and blood pressure in children and adolescents. The Cardiovascular Risk in Young Finns Study. Diabetologia 1995;38:1042-1050
-
(1995)
Diabetologia
, vol.38
, pp. 1042-1050
-
-
Raitakari, O.T.1
Porkka, K.V.2
Rönnemaa, T.3
-
3
-
-
0035847610
-
Low triglycerides-high high-density lipoprotein cholesterol and risk of ischemic heart disease
-
Jeppesen J, Hein HO, Suadicani P, Gyntelberg F. Low triglycerides-high high-density lipoprotein cholesterol and risk of ischemic heart disease. Arch Intern Med 2001;161:361-366 (Pubitemid 32116551)
-
(2001)
Archives of Internal Medicine
, vol.161
, Issue.3
, pp. 361-366
-
-
Jeppesen, J.1
Hein, H.O.2
Suadicani, P.3
Gyntelberg, F.4
-
4
-
-
0037339775
-
Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome
-
DOI 10.2337/diabetes.52.3.803
-
Watts GF, Barrett PH, Ji J, et al. Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome. Diabetes 2003;52:803-811 (Pubitemid 36323589)
-
(2003)
Diabetes
, vol.52
, Issue.3
, pp. 803-811
-
-
Watts, G.F.1
Barrett, P.H.R.2
Ji, J.3
Serone, A.P.4
Chan, D.C.5
Croft, K.D.6
Loehrer, F.7
Johnson, A.G.8
-
5
-
-
30744455025
-
Recent studies of lipoprotein kinetics in the metabolic syndrome and related disorders
-
Chan DC, Barrett PH, Watts GF. Recent studies of lipoprotein kinetics in the metabolic syndrome and related disorders. Curr Opin Lipidol 2006;17:28-36 (Pubitemid 43100300)
-
(2006)
Current Opinion in Lipidology
, vol.17
, Issue.1
, pp. 28-36
-
-
Chan, D.C.1
Barrett, P.H.R.2
Watts, G.F.3
-
6
-
-
0037049366
-
Diabetes, plasma insulin, and cardiovascular disease: Subgroup analysis from the Department of Veterans Affairs High-density Lipoprotein Intervention Trial (VA-HIT)
-
DOI 10.1001/archinte.162.22.2597
-
Rubins HB, Robins SJ, Collins D, et al. Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs High- Density Lipoprotein Intervention Trial (VA-HIT). Arch Intern Med 2002;162: 2597-2604 (Pubitemid 35453499)
-
(2002)
Archives of Internal Medicine
, vol.162
, Issue.22
, pp. 2597-2604
-
-
Rubins, H.B.1
Robins, S.J.2
Collins, D.3
Nelson, D.B.4
Elam, M.B.5
Schaefer, E.J.6
Faas, F.H.7
Anderson, J.W.8
-
7
-
-
64749095070
-
Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study
-
Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study Investigators
-
Scott R, O'Brien R, Fulcher G, et al.; Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study Investigators. Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetes Care 2009;32:493-498
-
(2009)
Diabetes Care
, vol.32
, pp. 493-498
-
-
Scott, R.1
O'Brien, R.2
Fulcher, G.3
-
8
-
-
28044452217
-
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
-
FIELD study investigators
-
Keech A, Simes RJ, Barter P, et al.; FIELD study investigators. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 2005;366:1849- 1861
-
(2005)
Lancet
, vol.366
, pp. 1849-1861
-
-
Keech, A.1
Simes, R.J.2
Barter, P.3
-
9
-
-
0014519590
-
A double-blind controlled trial of clofibrate in the treatment of diabetic retinopathy
-
Harrold BP, Marmion VJ, Gough KR. A double-blind controlled trial of clofibrate in the treatment of diabetic retinopathy. Diabetes 1969;18:285-291
-
(1969)
Diabetes
, vol.18
, pp. 285-291
-
-
Harrold, B.P.1
Marmion, V.J.2
Gough, K.R.3
-
10
-
-
17744402260
-
RETINOPATHIE DIABETIQUE EXSUDATIVE. INTERET DU CLOFIBRATE DANS LE TRAITEMENT DES EXSUDATS DURS, EN UTILISANT UNE POSOLOGIE REDUITE MAIS PROLONGEE PENDANT PLUSIEURS ANNEES
-
Dorne PA. Exudative diabetic retinopathy. The use of clofibrate in the treatment of hard exudates using a reduced but prolonged dosage over several years (author's transl). Arch Ophtalmol (Paris) 1977;37: 393-400 [in French] (Pubitemid 8118971)
-
(1977)
Archives d'Ophtalmologie et Revue Generale d'Ophtalmologie
, vol.37
, Issue.5
, pp. 393-400
-
-
Dorne, P.A.1
-
12
-
-
33846443997
-
Triglyceride: High-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist
-
DOI 10.1161/01.ATV.0000252790.70572.0c, PII 0004360520070200000017
-
Sprecher DL, Massien C, Pearce G, et al. Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist. Arterioscler Thromb Vasc Biol 2007;27:359-365 (Pubitemid 46143052)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.2
, pp. 359-365
-
-
Sprecher, D.L.1
Massien, C.2
Pearce, G.3
Billin, A.N.4
Perlstein, I.5
Willson, T.M.6
Hassall, D.G.7
Ancellin, N.8
Patterson, S.D.9
Lobe, D.C.10
Johnson, T.G.11
-
13
-
-
39649101196
-
Activation of peroxisome proliferatoractivated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men
-
Risérus U, Sprecher D, Johnson T, et al. Activation of peroxisome proliferatoractivated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men. Diabetes 2008;57:332-339
-
(2008)
Diabetes
, vol.57
, pp. 332-339
-
-
Risérus, U.1
Sprecher, D.2
Johnson, T.3
-
14
-
-
33847006604
-
Review: Peroxisome proliferator-activated receptor gamma and adipose tissue - Understanding obesityrelated changes in regulation of lipid and glucose metabolism
-
Sharma AM, Staels B. Review: Peroxisome proliferator-activated receptor gamma and adipose tissue - understanding obesityrelated changes in regulation of lipid and glucose metabolism. J Clin Endocrinol Metab 2007;92:386-395
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 386-395
-
-
Sharma, A.M.1
Staels, B.2
-
15
-
-
77954941113
-
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5
-
Choi JH, Banks AS, Estall JL, et al. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature 2010;466:451-456
-
(2010)
Nature
, vol.466
, pp. 451-456
-
-
Choi, J.H.1
Banks, A.S.2
Estall, J.L.3
-
16
-
-
67649839953
-
Effect of the dual peroxisome proliferator-activated receptoralpha/ gamma agonist aleglitazar on risk of cardiovascular disease in patients with type 2 diabetes (SYNCHRONY): A phase II, randomised, dose-ranging study
-
Henry RR, Lincoff AM, Mudaliar S, Rabbia M, Chognot C, Herz M. Effect of the dual peroxisome proliferator-activated receptoralpha/ gamma agonist aleglitazar on risk of cardiovascular disease in patients with type 2 diabetes (SYNCHRONY): a phase II, randomised, dose-ranging study. Lancet 2009;374:126-135
-
(2009)
Lancet
, vol.374
, pp. 126-135
-
-
Henry, R.R.1
Lincoff, A.M.2
Mudaliar, S.3
Rabbia, M.4
Chognot, C.5
Herz, M.6
-
17
-
-
0027717002
-
A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11
-
DOI 10.1016/0378-1119(93)90495-O
-
O'Dowd BF, Heiber M, Chan A, et al. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11. Gene 1993; 136:355-360 (Pubitemid 24049270)
-
(1993)
Gene
, vol.136
, Issue.1-2
, pp. 355-360
-
-
O'Dowd, B.F.1
Heiber, M.2
Chan, A.3
Heng, H.H.Q.4
Tsui, L.-C.5
Kennedy, J.L.6
Shi, X.7
Petronis, A.8
George, S.R.9
Nguyen, T.10
-
18
-
-
0035876612
-
The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism
-
DOI 10.1016/S0167-0115(01)00236-1, PII S0167011501002361
-
Tatemoto K, Takayama K, Zou MX, et al. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 2001;99:87-92 (Pubitemid 32522535)
-
(2001)
Regulatory Peptides
, vol.99
, Issue.2-3
, pp. 87-92
-
-
Tatemoto, K.1
Takayama, K.2
Zou, M.-X.3
Kumaki, I.4
Zhang, W.5
Kumano, K.6
Fujimiya, M.7
-
19
-
-
20144380036
-
Apelin, a newly identified adipokine up-regulated by insulin and obesity
-
DOI 10.1210/en.2004-1427
-
Boucher J, Masri B, Daviaud D, et al. Apelin, a newly identified adipokine upregulated by insulin and obesity. Endocrinology 2005;146:1764-1771 (Pubitemid 40396885)
-
(2005)
Endocrinology
, vol.146
, Issue.4
, pp. 1764-1771
-
-
Boucher, J.1
Masri, B.2
Daviaud, D.3
Gesta, S.4
Guigne, C.5
Mazzucotelli, A.6
Castan-Laurell, I.7
Tack, I.8
Knibiehler, B.9
Carpene, C.10
Audigier, Y.11
Saulnier-Blache, J.-S.12
Valet, P.13
-
20
-
-
22044453852
-
Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding
-
DOI 10.1016/j.regpep.2005.05.003, PII S0167011505001394
-
Heinonen MV, Purhonen AK, Miettinen P, et al. Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding. Regul Pept 2005;130:7-13 (Pubitemid 40966016)
-
(2005)
Regulatory Peptides
, vol.130
, Issue.1-2
, pp. 7-13
-
-
Heinonen, M.V.1
Purhonen, A.K.2
Miettinen, P.3
Paakkonen, M.4
Pirinen, E.5
Alhava, E.6
Akerman, K.7
Herzig, K.H.8
-
21
-
-
54849424539
-
Apelin stimulates glucose utilization in normal and obese insulin-resistant mice
-
Dray C, Knauf C, Daviaud D, et al. Apelin stimulates glucose utilization in normal and obese insulin-resistant mice. Cell Metab 2008;8:437-445
-
(2008)
Cell Metab
, vol.8
, pp. 437-445
-
-
Dray, C.1
Knauf, C.2
Daviaud, D.3
-
22
-
-
70349566593
-
Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
-
Neel JV. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet 1962;14:353-362
-
(1962)
Am J Hum Genet
, vol.14
, pp. 353-362
-
-
Neel, J.V.1
-
23
-
-
35148825449
-
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease1-3
-
Johnson RJ, Segal MS, Sautin Y, et al. Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am J Clin Nutr 2007;86:899-906 (Pubitemid 47538288)
-
(2007)
American Journal of Clinical Nutrition
, vol.86
, Issue.4
, pp. 899-906
-
-
Johnson, R.J.1
Segal, M.S.2
Sautin, Y.3
Nakagawa, T.4
Feig, D.I.5
Kang, D.-H.6
Gersch, M.S.7
Benner, S.8
Sanchez-Lozada, L.G.9
-
24
-
-
0025346072
-
Metabolic effects of dietary fructose
-
Hallfrisch J. Metabolic effects of dietary fructose. FASEB J 1990;4:2652-2660
-
(1990)
FASEB J
, vol.4
, pp. 2652-2660
-
-
Hallfrisch, J.1
-
25
-
-
77649117984
-
Dietary fructose causes tubulointerstitial injury in the normal rat kidney
-
Nakayama T, Kosugi T, Gersch M, et al. Dietary fructose causes tubulointerstitial injury in the normal rat kidney. Am J Physiol Renal Physiol 2010;298:F712-F720
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Nakayama, T.1
Kosugi, T.2
Gersch, M.3
-
26
-
-
60549110854
-
Hypothesis: Could excessive fructose intake and uric acid cause type 2 diabetes?
-
Johnson RJ, Perez-Pozo SE, Sautin YY, et al. Hypothesis: could excessive fructose intake and uric acid cause type 2 diabetes? Endocr Rev 2009;30:96-116
-
(2009)
Endocr Rev
, vol.30
, pp. 96-116
-
-
Johnson, R.J.1
Perez-Pozo, S.E.2
Sautin, Y.Y.3
-
27
-
-
33645560926
-
A causal role for uric acid in fructose-induced metabolic syndrome
-
DOI 10.1152/ajprenal.00140.2005
-
Nakagawa T, Hu H, Zharikov S, et al. A causal role for uric acid in fructoseinducedmetabolic syndrome. Am J Physiol Renal Physiol 2006;290:F625-F631 (Pubitemid 43724964)
-
(2006)
American Journal of Physiology - Renal Physiology
, vol.290
, Issue.3
-
-
Nakagawa, T.1
Hu, H.2
Zharikov, S.3
Tuttle, K.R.4
Short, R.A.5
Glushakova, O.6
Ouyang, X.7
Feig, D.I.8
Block, E.R.9
Herrera-Acosta, J.10
Patel, J.M.11
Johnson, R.J.12
-
28
-
-
77949541626
-
Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: Role of uric acid in the hypertensive response
-
Lond
-
Perez-Pozo SE, Schold J, Nakagawa T, Sánchez-Lozada LG, Johnson RJ, Lillo JL. Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response. Int J Obes (Lond) 2010; 34:454-461
-
(2010)
Int J Obes
, vol.34
, pp. 454-461
-
-
Perez-Pozo, S.E.1
Schold, J.2
Nakagawa, T.3
Sánchez-Lozada, L.G.4
Johnson, R.J.5
Lillo, J.L.6
-
29
-
-
4644257023
-
Changes in beverage intake between 1977 and 2001
-
DOI 10.1016/j.amepre.2004.05.005, PII S0749379704001229
-
Nielsen SJ, Popkin BM. Changes in beverage intake between 1977 and 2001. Am J Prev Med 2004;27:205-210 (Pubitemid 39278319)
-
(2004)
American Journal of Preventive Medicine
, vol.27
, Issue.3
, pp. 205-210
-
-
Nielsen, S.J.1
Popkin, B.M.2
-
30
-
-
34848830434
-
Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): A population based study
-
DOI 10.1016/j.jhep.2007.06.020, PII S0168827807004278
-
Zelber-Sagi S, Nitzan-Kaluski D, Goldsmith R, et al. Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): a population based study. J Hepatol 2007;47:711-717 (Pubitemid 47503432)
-
(2007)
Journal of Hepatology
, vol.47
, Issue.5
, pp. 711-717
-
-
Zelber-Sagi, S.1
Nitzan-Kaluski, D.2
Goldsmith, R.3
Webb, M.4
Blendis, L.5
Halpern, Z.6
Oren, R.7
-
31
-
-
11244315795
-
Uric acid, evolution and primitive cultures
-
DOI 10.1016/j.semnephrol.2004.09.002, PII S0270929504001457, Uric Acid in Cardiovascular and Renal Disease
-
Johnson RJ, Titte S, Cade JR, Rideout BA, Oliver WJ. Uric acid, evolution and primitive cultures. Semin Nephrol 2005;25: 3-8 (Pubitemid 40128142)
-
(2005)
Seminars in Nephrology
, vol.25
, Issue.1
, pp. 3-8
-
-
Johnson, R.J.1
Titte, S.2
Cade, J.R.3
Rideout, B.A.4
Oliver, W.J.5
-
32
-
-
0035723995
-
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism
-
Mazzali M, Hughes J, Kim YG, et al. Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism. Hypertension 2001;38:1101-1106 (Pubitemid 34252813)
-
(2001)
Hypertension
, vol.38
, Issue.5
, pp. 1101-1106
-
-
Mazzali, M.1
Hughes, J.2
Kim, Y.-G.3
Jefferson, J.A.4
Kang, D.-H.5
Gordon, K.L.6
Lan, H.Y.7
Kivlighn, S.8
Johnson, R.J.9
-
33
-
-
0036083844
-
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism
-
Mazzali M, Kanellis J, Han L, et al. Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol 2002;282:F991-F997 (Pubitemid 34654464)
-
(2002)
American Journal of Physiology - Renal Physiology
, vol.282
, Issue.6
-
-
Mazzali, M.1
Kanellis, J.2
Han, L.3
Feng, L.4
Xia, Y.-Y.5
Chen, Q.6
Kang, D.-H.7
Gordon, K.L.8
Watanabe, S.9
Nakagawa, T.10
Lan, H.Y.11
Johnson, R.J.12
-
34
-
-
0036713048
-
Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity
-
DOI 10.1161/01.HYP.0000028589.66335.AA
-
Watanabe S, Kang DH, Feng L, et al. Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity. Hypertension 2002;40:355-360 (Pubitemid 35006723)
-
(2002)
Hypertension
, vol.40
, Issue.3
, pp. 355-360
-
-
Watanabe, S.1
Kang, D.-H.2
Feng, L.3
Nakagawa, T.4
Kanellis, J.5
Lan, H.6
Mazzali, M.7
Johnson, R.J.8
-
35
-
-
0042334471
-
Hyperuricemia in childhood primary hypertension
-
DOI 10.1161/01.HYP.0000085858.66548.59
-
Feig DI, Johnson RJ. Hyperuricemia in childhood primary hypertension. Hypertension 2003;42:247-252 (Pubitemid 37093468)
-
(2003)
Hypertension
, vol.42
, Issue.3
, pp. 247-252
-
-
Feig, D.I.1
Johnson, R.J.2
-
36
-
-
50449095362
-
Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: A randomized trial
-
Feig DI, Soletsky B, Johnson RJ. Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial. JAMA 2008; 300:924-932
-
(2008)
JAMA
, vol.300
, pp. 924-932
-
-
Feig, D.I.1
Soletsky, B.2
Johnson, R.J.3
-
38
-
-
33645560926
-
A causal role for uric acid in fructose-induced metabolic syndrome
-
DOI 10.1152/ajprenal.00140.2005
-
Nakagawa T, Hu H, Zharikov S, et al. A causal role for uric acid in fructoseinduced metabolic syndrome. Am J Physiol Renal Physiol 2006;290:F625-F631 (Pubitemid 43724964)
-
(2006)
American Journal of Physiology - Renal Physiology
, vol.290
, Issue.3
-
-
Nakagawa, T.1
Hu, H.2
Zharikov, S.3
Tuttle, K.R.4
Short, R.A.5
Glushakova, O.6
Ouyang, X.7
Feig, D.I.8
Block, E.R.9
Herrera-Acosta, J.10
Patel, J.M.11
Johnson, R.J.12
-
39
-
-
34547733397
-
Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress
-
DOI 10.1152/ajpcell.00600.2006
-
Sautin YY, Nakagawa T, Zharikov S, Johnson RJ. Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. Am J Physiol Cell Physiol 2007;293:C584-C596 (Pubitemid 47235197)
-
(2007)
American Journal of Physiology - Cell Physiology
, vol.293
, Issue.2
-
-
Sautin, Y.Y.1
Nakagawa, T.2
Zharikov, S.3
Johnson, R.J.4
-
40
-
-
43049170503
-
Fructose consumption as a risk factor for nonalcoholic fatty liver disease
-
Ouyang X, Cirillo P, Sautin Y, et al. Fructose consumption as a risk factor for nonalcoholic fatty liver disease. J Hepatol 2008; 48:993-999
-
(2008)
J Hepatol
, vol.48
, pp. 993-999
-
-
Ouyang, X.1
Cirillo, P.2
Sautin, Y.3
-
41
-
-
28844433635
-
Medicine: The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
DOI 10.1126/science.1120781
-
Shaw RJ, Lamia KA, Vasquez D, et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 2005;310:1642-1646 (Pubitemid 41780780)
-
(2005)
Science
, vol.310
, Issue.5754
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.-H.4
Bardeesy, N.5
DePinho, R.A.6
Montminy, M.7
Cantley, L.C.8
-
42
-
-
79251612707
-
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
-
GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group; Wellcome Trust Case Control Consortium2;MAGIC investigators
-
Zhou K, Bellenguez C, Spencer CC, et al.; GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group; Wellcome Trust Case Control Consortium2;MAGIC investigators. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet 2011; 43:117-120
-
(2011)
Nat Genet
, vol.43
, pp. 117-120
-
-
Zhou, K.1
Bellenguez, C.2
Spencer, C.C.3
-
43
-
-
44349184864
-
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
-
Fu X, Wan S, Lyu YL, Liu LF, Qi H. Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation. PLoS One 2008;3:e2009
-
(2008)
PLoS One
, vol.3
, pp. 2009
-
-
Fu, X.1
Wan, S.2
Lyu, Y.L.3
Liu, L.F.4
Qi, H.5
-
44
-
-
34848840368
-
Structural basis for AMP binding to mammalian AMP-activated protein kinase
-
DOI 10.1038/nature06161, PII NATURE06161
-
Xiao B, Heath R, Saiu P, et al. Structural basis for AMP binding to mammalian AMP-activated protein kinase. Nature 2007;449: 496-500 (Pubitemid 47509548)
-
(2007)
Nature
, vol.449
, Issue.7161
, pp. 496-500
-
-
Xiao, B.1
Heath, R.2
Saiu, P.3
Leiper, F.C.4
Leone, P.5
Jing, C.6
Walker, P.A.7
Haire, L.8
Eccleston, J.F.9
Davis, C.T.10
Martin, S.R.11
Carling, D.12
Gamblin, S.J.13
-
45
-
-
44449103256
-
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
-
DOI 10.1042/BJ20080557
-
Huang X, Wullschleger S, Shpiro N, et al. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice. Biochem J 2008; 412:211-221 (Pubitemid 351758227)
-
(2008)
Biochemical Journal
, vol.412
, Issue.2
, pp. 211-221
-
-
Huang, X.1
Wullschleger, S.2
Shpiro, M.3
McGuire, V.A.4
Sakamoto, K.5
Woods, Y.L.6
McBurnie, W.7
Fleming, S.8
Alessi, D.R.9
-
46
-
-
80051970187
-
Insulin concerns and promises
-
Bloomgarden ZT. Insulin concerns and promises. Diabetes Care 2011;34:e100-e106
-
(2011)
Diabetes Care
, vol.34
-
-
Bloomgarden, Z.T.1
-
48
-
-
33746866265
-
Diabetes mellitus and breast cancer: A retrospective population-based cohort study
-
DOI 10.1007/s10549-006-9172-5
-
Lipscombe LL, Goodwin PJ, Zinman B, McLaughlin JR, Hux JE. Diabetes mellitus and breast cancer: a retrospective population-based cohort study. Breast Cancer Res Treat 2006;98:349-356 (Pubitemid 44195606)
-
(2006)
Breast Cancer Research and Treatment
, vol.98
, Issue.3
, pp. 349-356
-
-
Lipscombe, L.L.1
Goodwin, P.J.2
Zinman, B.3
McLaughlin, J.R.4
Hux, J.E.5
-
49
-
-
72549116243
-
Diabetes and cancer
-
Vigneri P, Frasca F, Sciacca L, Pandini G, Vigneri R. Diabetes and cancer. Endocr Relat Cancer 2009;16:1103-1123
-
(2009)
Endocr Relat Cancer
, vol.16
, pp. 1103-1123
-
-
Vigneri, P.1
Frasca, F.2
Sciacca, L.3
Pandini, G.4
Vigneri, R.5
-
50
-
-
47349117519
-
Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies
-
DOI 10.1080/13813450801954451, PII 791408005, Proceedings of the Workshop on Insulin and Cancer
-
Pisani P. Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies. Arch Physiol Biochem 2008;114:63-70 (Pubitemid 351998745)
-
(2008)
Archives of Physiology and Biochemistry
, vol.114
, Issue.1
, pp. 63-70
-
-
Pisani, P.1
-
52
-
-
77953537179
-
Glucose-lowering agents and cancer mortality rates in type 2 diabetes: Assessing effects of time-varying exposure
-
Bowker SL, Yasui Y, Veugelers P, Johnson JA. Glucose-lowering agents and cancer mortality rates in type 2 diabetes: assessing effects of time-varying exposure. Diabetologia 2010;53:1631-1637
-
(2010)
Diabetologia
, vol.53
, pp. 1631-1637
-
-
Bowker, S.L.1
Yasui, Y.2
Veugelers, P.3
Johnson, J.A.4
-
53
-
-
0036138579
-
Fasting insulin and outcome in early-stage breast cancer: Results of a prospective cohort study
-
DOI 10.1200/JCO.20.1.42
-
Goodwin PJ, Ennis M, Pritchard KI, et al. Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study. J Clin Oncol 2002;20:42-51 (Pubitemid 34032594)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.1
, pp. 42-51
-
-
Goodwin, P.J.1
Ennis, M.2
Pritchard, K.I.3
Trudeau, M.E.4
Koo, J.5
Madarnas, Y.6
Hartwick, W.7
Hoffman, B.8
Hood, N.9
-
54
-
-
54349083481
-
Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: A long-term survival analysis
-
Ma J, Li H, Giovannucci E, et al. Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis. Lancet Oncol 2008;9:1039-1047
-
(2008)
Lancet Oncol
, vol.9
, pp. 1039-1047
-
-
Ma, J.1
Li, H.2
Giovannucci, E.3
-
55
-
-
34047174592
-
The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer
-
DOI 10.2174/138161207780249173
-
Belfiore A. The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer. Curr Pharm Des 2007; 13:671-686 (Pubitemid 46510744)
-
(2007)
Current Pharmaceutical Design
, vol.13
, Issue.7
, pp. 671-686
-
-
Belfiore, A.1
-
56
-
-
57749089652
-
Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival
-
Law JH, Habibi G, Hu K, et al. Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Res 2008;68:10238-10246
-
(2008)
Cancer Res
, vol.68
, pp. 10238-10246
-
-
Law, J.H.1
Habibi, G.2
Hu, K.3
-
57
-
-
78649302320
-
Metformin and cancer risk in diabetic patients: A systematic review and metaanalysis
-
Phila
-
Decensi A, Puntoni M, Goodwin P, et al. Metformin and cancer risk in diabetic patients: a systematic review and metaanalysis. Cancer Prev Res (Phila) 2010;3: 1451-1461
-
(2010)
Cancer Prev Res
, vol.3
, pp. 1451-1461
-
-
Decensi, A.1
Puntoni, M.2
Goodwin, P.3
-
59
-
-
77956414137
-
Chemoprevention meets glucose control
-
Phila
-
Engelman JA, Cantley LC. Chemoprevention meets glucose control. Cancer Prev Res (Phila) 2010;3:1049-1052
-
(2010)
Cancer Prev Res
, vol.3
, pp. 1049-1052
-
-
Engelman, J.A.1
Cantley, L.C.2
-
60
-
-
67749144226
-
Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer
-
Jiralerspong S, Palla SL, Giordano SH, et al. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J Clin Oncol 2009;27:3297-3302
-
(2009)
J Clin Oncol
, vol.27
, pp. 3297-3302
-
-
Jiralerspong, S.1
Palla, S.L.2
Giordano, S.H.3
-
61
-
-
67650514082
-
Metformin induces unique biological and molecular responses in triple negative breast cancer cells
-
Liu B, Fan Z, Edgerton SM, et al. Metformin induces unique biological and molecular responses in triple negative breast cancer cells. Cell Cycle 2009;8:2031-2040
-
(2009)
Cell Cycle
, vol.8
, pp. 2031-2040
-
-
Liu, B.1
Fan, Z.2
Edgerton, S.M.3
-
62
-
-
70450021431
-
mTOR inhibitors and the anti-diabetic biguanide metformin: New insights into the molecular management of breast cancer resistance to the HER2 tyrosine kinase inhibitor lapatinib (Tykerb)
-
Vázquez-Martín A, Oliveras-Ferraros C, del Barco S, Martín-Castillo B, Menéndez JA. mTOR inhibitors and the anti-diabetic biguanide metformin: new insights into the molecular management of breast cancer resistance to the HER2 tyrosine kinase inhibitor lapatinib (Tykerb). Clin Transl Oncol 2009;11:455-459
-
(2009)
Clin Transl Oncol
, vol.11
, pp. 455-459
-
-
Vázquez-Martín, A.1
Oliveras-Ferraros, C.2
Del Barco, S.3
Martín-Castillo, B.4
Menéndez, J.A.5
-
63
-
-
77956150294
-
Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase
-
Brown KA, Hunger NI, Docanto M, Simpson ER. Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase. Breast Cancer Res Treat 2010;123:591-596
-
(2010)
Breast Cancer Res Treat
, vol.123
, pp. 591-596
-
-
Brown, K.A.1
Hunger, N.I.2
Docanto, M.3
Simpson, E.R.4
-
64
-
-
77956415337
-
Metformin prevents tobacco carcinogen-induced lung tumorigenesis
-
Phila
-
Memmott RM, Mercado JR, Maier CR, Kawabata S, Fox SD, Dennis PA. Metformin prevents tobacco carcinogen-induced lung tumorigenesis. Cancer Prev Res (Phila) 2010;3:1066-1076
-
(2010)
Cancer Prev Res
, vol.3
, pp. 1066-1076
-
-
Memmott, R.M.1
Mercado, J.R.2
Maier, C.R.3
Kawabata, S.4
Fox, S.D.5
Dennis, P.A.6
-
65
-
-
77954468475
-
Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase
-
Hosono K, Endo H, Takahashi H, et al. Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase. Mol Carcinog 2010;49:662-671
-
(2010)
Mol Carcinog
, vol.49
, pp. 662-671
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
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