Critical hydrogen bonds and protonation states of pyridoxal 5′-phosphate revealed by NMR

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1814, Issue 11, 2011, Pages 1426-1437

  Limbach, Hans Heinrich ^a   Chan Huot, Monique ^a   Sharif, Shasad ^a   Tolstoy, Peter M ^a   Shenderovich, Ilya G ^a   Denisov, Gleb S ^b   Toney, Michael D ^c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aspartate aminotransferase; Hydrogen bonding; Protonation state; Pyridoxal 5 phosphate; Solid and liquid state NMR; Tautomerism

Indexed keywords

AMPHOLYTE; ASPARTATE AMINOTRANSFERASE; ASPARTIC ACID; ENVIRONMENTAL CHEMICAL; HISTIDINE; IMIDAZOLE; LYSINE; NITROGEN 15; PROTEIN; PYRIDINE; PYRIDOXAL 5 PHOSPHATE; WATER; AMINE; PROTON;

ACID BASE BALANCE; AQUEOUS SOLUTION; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ENZYME MECHANISM; ENZYMOLOGY; GEOMETRY; HYDROGEN BOND; LIQUID; NITROGEN NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON TRANSPORT; REVIEW; SOLID STATE; SOLVATE; TAUTOMERIZATION; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLUTION AND SOLUBILITY;

AMINES; HYDROGEN BONDING; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; PROTONS; PYRIDOXAL PHOSPHATE; SOLUTIONS; WATER;

EID: 80054681734     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.06.004     Document Type: Review

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