-
1
-
-
78650275970
-
SmartCrystal combination technology - Scale up from lab to pilot scale and long term stability
-
L. Al Shaal, R.H. Müller, and R. Shegokar smartCrystal combination technology - scale up from lab to pilot scale and long term stability Pharmazie 65 2010 877 884
-
(2010)
Pharmazie
, vol.65
, pp. 877-884
-
-
Al Shaal, L.1
Müller, R.H.2
Shegokar, R.3
-
2
-
-
0036141823
-
Methods for testing antioxidant activity
-
DOI 10.1039/b009171p
-
M. Antolovich, P.D. Prenzler, E. Patsalides, S. McDonald, and K. Robards Methods for testing antioxidant activity Analyst 127 2002 183 198 (Pubitemid 34081656)
-
(2002)
Analyst
, vol.127
, Issue.1
, pp. 183-198
-
-
Antolovich, M.1
Prenzler, P.D.2
Patsalides, E.3
McDonald, S.4
Robards, K.5
-
3
-
-
27944449998
-
Design of biodegradable nanoparticles: A novel approach to encapsulating poorly soluble phytochemical ellagic acid
-
DOI 10.1088/0957-4484/16/12/014, PII S0957448405045599
-
I. Bala, V. Bhardwaj, S. Hariharan, J. Sitterberg, U. Bakowsky, and M.N.V.R. Kumar Design of biodegradable nanoparticles: a novel approach to encapsulating poorly soluble phytochemical ellagic acid Nanotechnology 16 2005 2819 2822 (Pubitemid 41677035)
-
(2005)
Nanotechnology
, vol.16
, Issue.12
, pp. 2819-2822
-
-
Bala, I.1
Bhardwaj, V.2
Hariharan, S.3
Sitterberg, J.4
Bakowsky, U.5
Ravi Kumar, M.N.V.6
-
5
-
-
0026735598
-
The relationship between particle size and solubility
-
G. Buckton, and A.E. Beezer The relationship between particle size and solubility Int. J. Pharm. 82 1992 R7 R10
-
(1992)
Int. J. Pharm.
, vol.82
-
-
Buckton, G.1
Beezer, A.E.2
-
6
-
-
75749088052
-
Development of topical nanoemulsions containing quercetin and 3-O-methylquercetin
-
D. Fasolo, V.L. Bassani, and H.F. Teixeira Development of topical nanoemulsions containing quercetin and 3-O-methylquercetin Pharmazie 64 2009 726 730
-
(2009)
Pharmazie
, vol.64
, pp. 726-730
-
-
Fasolo, D.1
Bassani, V.L.2
Teixeira, H.F.3
-
7
-
-
0031277610
-
Antioxidant activity of flavones from Scutellaria baicalensis in lecithin liposomes
-
J. Gabrielska, J. Oszmianski, R. Zylka, and M. Komorowska Antioxidant activity of flavones from Scutellaria baicalensis in lecithin liposomes Z. Naturforsch. C - J. Biosci. 52 1997 817 823 (Pubitemid 28091354)
-
(1997)
Zeitschrift fur Naturforschung - Section C Journal of Biosciences
, vol.52
, Issue.11-12
, pp. 817-823
-
-
Gabrielska, J.1
Oszmianski, J.2
Zylka, R.3
Komorowska, M.4
-
8
-
-
5644262626
-
Encapsulation of naturally occurring flavonoids into liposomes: Physicochemical properties and biological activity against human cancer cell lines
-
DOI 10.1211/0022357044382
-
M. Goniotaki, S. Hatziantoniou, K. Dimas, M. Wagner, and C. Demetzos Encapsulation of naturally occurring flavonoids into liposomes: physicochemical properties and biological activity against human cancer cell lines J. Pharm. Pharmacol. 56 2004 1217 1224 (Pubitemid 39368991)
-
(2004)
Journal of Pharmacy and Pharmacology
, vol.56
, Issue.10
, pp. 1217-1224
-
-
Goniotaki, M.1
Hatziantoniou, S.2
Dimas, K.3
Wagner, M.4
Demetzos, C.5
-
9
-
-
0026688245
-
Antioxidant potential of ferulic acid
-
E. Graf Antioxidant potential of ferulic acid Free Radic. Biol. Med. 13 1992 435 448
-
(1992)
Free Radic. Biol. Med.
, vol.13
, pp. 435-448
-
-
Graf, E.1
-
10
-
-
33744478401
-
Free radical theory of aging: An update - Increasing the functional life span
-
DOI 10.1196/annals.1354.003
-
D. Harman Free radical theory of aging: an update: increasing the functional life span Ann. N. Y. Acad. Sci. 1067 2006 10 21 (Pubitemid 43806304)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1067
, Issue.1
, pp. 10-21
-
-
Harman, D.1
-
11
-
-
0036849077
-
The biochemistry and medical significance of the flavonoids
-
DOI 10.1016/S0163-7258(02)00298-X, PII S016372580200298X
-
B.H. Havsteen The biochemistry and medical significance of the flavonoids Pharmacol. Therapeut. 96 2002 67 202 (Pubitemid 35356564)
-
(2002)
Pharmacology and Therapeutics
, vol.96
, Issue.2-3
, pp. 67-202
-
-
Havsteen, B.H.1
-
12
-
-
21844461846
-
Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine
-
DOI 10.1016/j.ijpharm.2005.05.014, PII S0378517305003212
-
J. Hecq, M. Deleers, D. Fanara, H. Vranckx, and K. Amighi Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine Int. J. Pharm. 299 2005 167 177 (Pubitemid 40962418)
-
(2005)
International Journal of Pharmaceutics
, vol.299
, Issue.1-2
, pp. 167-177
-
-
Hecq, J.1
Deleers, M.2
Fanara, D.3
Vranckx, H.4
Amighi, K.5
-
13
-
-
42249084559
-
Nutrients and phytochemicals: From bioavailability to bioefficacy beyond antioxidants
-
B. Holst, and G. Williamson Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants Curr. Opin. Biotechnol. 19 2008 73 82
-
(2008)
Curr. Opin. Biotechnol.
, vol.19
, pp. 73-82
-
-
Holst, B.1
Williamson, G.2
-
14
-
-
33344478634
-
Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs
-
DOI 10.1016/j.jconrel.2005.11.013, PII S0168365905006565
-
J. Jinno, N. Kamada, M. Miyake, K. Yamada, T. Mukai, M. Odomi, H. Toguchi, G.G. Liversidge, K. Higaki, and T. Kimura Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs J. Control. Release 111 2006 56 64 (Pubitemid 43289995)
-
(2006)
Journal of Controlled Release
, vol.111
, Issue.1-2
, pp. 56-64
-
-
Jinno, J.-I.1
Kamada, N.2
Miyake, M.3
Yamada, K.4
Mukai, T.5
Odomi, M.6
Toguchi, H.7
Liversidge, G.G.8
Higaki, K.9
Kimura, T.10
-
15
-
-
62749092217
-
NanoCrystal® Technology: A formulation approach for poorly water soluble compounds
-
I.L. Sciences, 8-10th September, Brussels
-
C.M. Keck NanoCrystal® Technology: a formulation approach for poorly water soluble compounds I.L. Sciences, Particle Design for APIs and Drug Products 8-10th September, Brussels 2008
-
(2008)
Particle Design for APIs and Drug Products
-
-
Keck, C.M.1
-
16
-
-
76149089279
-
Second generation of drug nanocrystals for delivery of poorly soluble drugs: SmartCrystals technology
-
C.M. Keck, S. Kobierski, R. Mauludin, and R.H. Müller Second generation of drug nanocrystals for delivery of poorly soluble drugs: smartCrystals technology Dosis 2 2008 124 128
-
(2008)
Dosis
, vol.2
, pp. 124-128
-
-
Keck, C.M.1
Kobierski, S.2
Mauludin, R.3
Müller, R.H.4
-
17
-
-
84864611797
-
Influence of different stabilizers on particle size of apigenin nanosuspensions produced by high pressure homogenization
-
Controlled Release Society, Inc. Copenhagen
-
J. Kerč, S. Kobierski, C.M. Keck, and R.H. Müller Influence of different stabilizers on particle size of apigenin nanosuspensions produced by high pressure homogenization International Symposium on Controlled Release of Bioactive Materials vol. 36 2009 Controlled Release Society, Inc. Copenhagen p. 3885
-
(2009)
International Symposium on Controlled Release of Bioactive Materials
, vol.36
, pp. 3885
-
-
Kerč, J.1
Kobierski, S.2
Keck, C.M.3
Müller, R.H.4
-
18
-
-
49949101484
-
Effect of reaction temperatures and media on crystal structure of colloidal nanocrystals synthesized from an aerosol flow system
-
D.J. Kim, H.D. Jang, E.J. Kim, and K.K. Koo Effect of reaction temperatures and media on crystal structure of colloidal nanocrystals synthesized from an aerosol flow system Ultramicroscopy 108 2008 1278 1282
-
(2008)
Ultramicroscopy
, vol.108
, pp. 1278-1282
-
-
Kim, D.J.1
Jang, H.D.2
Kim, E.J.3
Koo, K.K.4
-
19
-
-
45449112311
-
Microprecipitation method for preparing submicron suspensions
-
Baxter International Inc. Deerfield, IL, USA
-
J.E. Kipp, J.C.T. Wong, M.J. Doty, and C.L. Rebbeck Microprecipitation method for preparing submicron suspensions United States Patent 6,607,784 2003 Baxter International Inc. Deerfield, IL, USA
-
(2003)
United States Patent 6,607,784
-
-
Kipp, J.E.1
Wong, J.C.T.2
Doty, M.J.3
Rebbeck, C.L.4
-
20
-
-
84864619872
-
Preparation and physical evaluation of ascorbyl palmitate nanosuspensions
-
Atlanta, USA
-
S. Kobierski, L. Al Shaal, C.M. Keck, J. Kerč, and R.H. Müller Preparation and physical evaluation of ascorbyl palmitate nanosuspensions AAPS Annual Meeting Atlanta, USA 2008
-
(2008)
AAPS Annual Meeting
-
-
Kobierski, S.1
Al Shaal, L.2
Keck, C.M.3
Kerč, J.4
Müller, R.H.5
-
22
-
-
75749111422
-
Resveratrol nanosuspensions for dermal application - Production, characterization, and physical stability
-
S. Kobierski, K. Ofori-Kwakye, R.H. Muller, and C.M. Keck Resveratrol nanosuspensions for dermal application - production, characterization, and physical stability Pharmazie 64 2009 741 747
-
(2009)
Pharmazie
, vol.64
, pp. 741-747
-
-
Kobierski, S.1
Ofori-Kwakye, K.2
Muller, R.H.3
Keck, C.M.4
-
23
-
-
0036867895
-
Oxidation of biological systems: Oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification
-
DOI 10.1080/01926230290166724
-
R. Kohen, and A. Nyska Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification Toxicol. Pathol. 30 2002 620 650 (Pubitemid 36018731)
-
(2002)
Toxicologic Pathology
, vol.30
, Issue.6
, pp. 620-650
-
-
Kohen, R.1
Nyska, A.2
-
24
-
-
80054698892
-
Workshop Nanotechnology - Solid particles, lipids and nanocomplexes
-
Cologne, Germany
-
G. Liversidge Workshop Nanotechnology - solid particles, lipids and nanocomplexes IIR Drug Delivery Partnerships™ Meeting Cologne, Germany 2003
-
(2003)
IIR Drug Delivery Partnerships™ Meeting
-
-
Liversidge, G.1
-
25
-
-
77952243245
-
Role of antioxidants in the skin: Anti-aging effects
-
H. Masaki Role of antioxidants in the skin: anti-aging effects J. Dermatol. Sci. 58 2010 85 90
-
(2010)
J. Dermatol. Sci.
, vol.58
, pp. 85-90
-
-
Masaki, H.1
-
26
-
-
61349095957
-
Development of an oral rutin nanocrystal formulation
-
R. Mauludin, R.H. Müller, and C.M. Keck Development of an oral rutin nanocrystal formulation Int. J. Pharm. 370 2009 202 209
-
(2009)
Int. J. Pharm.
, vol.370
, pp. 202-209
-
-
Mauludin, R.1
Müller, R.H.2
Keck, C.M.3
-
27
-
-
62749150964
-
Production and characterization of Hesperetin nanosuspensions for dermal delivery
-
P.R. Mishra, L. Al Shaal, R.H. Müller, and C.M. Keck Production and characterization of Hesperetin nanosuspensions for dermal delivery Int. J. Pharm. 371 2009 182 189
-
(2009)
Int. J. Pharm.
, vol.371
, pp. 182-189
-
-
Mishra, P.R.1
Al Shaal, L.2
Müller, R.H.3
Keck, C.M.4
-
28
-
-
0029034381
-
Protective effect evaluation of free radical scavengers on UVB induced human cutaneous erythema by skin reflectance spectrophotometry
-
L. Montenegro, F. Bonina, L. Rigano, S. Giogilli, and S. Sirigu Protective effect evaluation of free radical scavengers on UVB induced human cutaneous erythema by skin reflectance spectrophotometry Int. J. Cosmetic Sci. 17 1995 91 103
-
(1995)
Int. J. Cosmetic Sci.
, vol.17
, pp. 91-103
-
-
Montenegro, L.1
Bonina, F.2
Rigano, L.3
Giogilli, S.4
Sirigu, S.5
-
29
-
-
84885077527
-
Method for carefully producing ultrafine particle suspensions and ultrafine particles and use thereof
-
W.I. Property, ABBOTT GmbH & CO.KG Germany
-
J. Möschwitzer, and A. Lemke Method for carefully producing ultrafine particle suspensions and ultrafine particles and use thereof W.I. Property, PCT/EP2006/003377 2007 ABBOTT GmbH & CO.KG Germany
-
(2007)
PCT/EP2006/003377
-
-
Möschwitzer, J.1
Lemke, A.2
-
31
-
-
0027427273
-
Emulsions for intravenous application. II. Destabilisation and stabilisation mechanisms in fat emulsions
-
R.H. Müller, and S. Heinemann Emulsions for Intravenous Application. II. Destabilisation and stabilisation mechanisms in fat emulsions Die Pharm. Ind. 55 1993 948 953 (Pubitemid 23329214)
-
(1993)
Pharmazeutische Industrie
, vol.55
, Issue.10
, pp. 948-953
-
-
Muller, R.H.1
Heinemann, S.2
-
32
-
-
0037177516
-
Buparvaquone mucoadhesive nanosuspension: Preparation, optimisation and long-term stability
-
DOI 10.1016/S0378-5173(02)00040-6, PII S0378517302000406
-
R.H. Müller, and C. Jacobs Buparvaquone mucoadhesive nanosuspension: preparation, optimisation and long-term stability Int. J. Pharm. 237 2002 151 161 (Pubitemid 34310488)
-
(2002)
International Journal of Pharmaceutics
, vol.237
, Issue.1-2
, pp. 151-161
-
-
Muller, R.H.1
Jacobs, C.2
-
33
-
-
0002819692
-
Nanosuspensions for the formulation of poorly soluble drugs
-
F. Nielloud, G. Marti-Mestres, Marcel Dekker
-
R.H. Müller, C. Jacobs, and O. Kayser Nanosuspensions for the formulation of poorly soluble drugs F. Nielloud, G. Marti-Mestres, Pharmaceutical Emulsions and Suspensions 2000 Marcel Dekker 383 407
-
(2000)
Pharmaceutical Emulsions and Suspensions
, pp. 383-407
-
-
Müller, R.H.1
Jacobs, C.2
Kayser, O.3
-
35
-
-
84884284000
-
Method and device for producing very fine particles and coating such particles
-
W.I. Property, ABBOTT GmbH & CO. KG Germany
-
R.H. Müller, and J. Möschwitzer Method and device for producing very fine particles and coating such particles W.I. Property, PCT/EP2006/009930 2007 ABBOTT GmbH & CO. KG Germany
-
(2007)
PCT/EP2006/009930
-
-
Müller, R.H.1
Möschwitzer, J.2
-
36
-
-
77954424265
-
Effects of a nanocomplex containing antioxidant lipid, and amino acid on thermal burn wound surface
-
A.A. Naumov, Y.V. Shatalin, and M.M. Potselueva Effects of a nanocomplex containing antioxidant lipid, and amino acid on thermal burn wound surface Bull. Exp. Biol. Med. 149 2010 62 66
-
(2010)
Bull. Exp. Biol. Med.
, vol.149
, pp. 62-66
-
-
Naumov, A.A.1
Shatalin, Y.V.2
Potselueva, M.M.3
-
37
-
-
78851469731
-
Resveratrol in cancer management: Where are we and where we go from here?
-
M. Ndiaye, R. Kumar, and N. Ahmad Resveratrol in cancer management: where are we and where we go from here? Resveratrol Health 1215 2011 144 149
-
(2011)
Resveratrol Health
, vol.1215
, pp. 144-149
-
-
Ndiaye, M.1
Kumar, R.2
Ahmad, N.3
-
38
-
-
0002223748
-
Dissolution properties of soluble drugs: Theoretical background and possibilities to improve the dissolution behavior
-
R.H. Müller, S. Benita, B. Böhm, Stuttgart
-
C. Nyström Dissolution properties of soluble drugs: theoretical background and possibilities to improve the dissolution behavior R.H. Müller, S. Benita, B. Böhm, Medpharm Scientific 1998 Stuttgart 143 147
-
(1998)
Medpharm Scientific
, pp. 143-147
-
-
Nyström, C.1
-
41
-
-
77955442212
-
Nanocrystals for use in topical formulations and method of production thereof
-
Abbott GmbH, Petersen, R.D Germany
-
R.D. Petersen Nanocrystals for use in topical formulations and method of production thereof PCT/EP2007/009943 2006 Abbott GmbH, Petersen, R.D Germany
-
(2006)
PCT/EP2007/009943
-
-
Petersen, R.D.1
-
42
-
-
34547790677
-
Interplay among oxidants, antioxidants, and cytokines in skin disorders: Present status and future considerations
-
DOI 10.1016/j.biopha.2007.05.010, PII S075333220700114X
-
M. Portugal, V. Barak, I. Ginsburg, and R. Kohen Interplay among oxidants, antioxidants, and cytokines in skin disorders: present status and future considerations Biomed. Pharmacother. 61 2007 412 422 (Pubitemid 47239346)
-
(2007)
Biomedicine and Pharmacotherapy
, vol.61
, Issue.7
, pp. 412-422
-
-
Portugal, M.1
Barak, V.2
Ginsburg, I.3
Kohen, R.4
-
44
-
-
0001893978
-
Oxidative reactions in and on the skin: Mechanism and prevention
-
M.M. Rieger, and M. Pains Oxidative reactions in and on the skin: mechanism and prevention Cosmetic Toiletries 108 1993 43 56
-
(1993)
Cosmetic Toiletries
, vol.108
, pp. 43-56
-
-
Rieger, M.M.1
Pains, M.2
-
45
-
-
0036724946
-
UV-light-induced signal cascades and skin aging
-
DOI 10.1016/S1568-1637(02)00024-7, PII S1568163702000247
-
L. Rittie, and G.J. Fisher UV-light-induced signal cascades and skin aging Ageing Res. Rev. 1 2002 705 720 (Pubitemid 38344146)
-
(2002)
Ageing Research Reviews
, vol.1
, Issue.4
, pp. 705-720
-
-
Rittie, L.1
Fisher, G.J.2
-
47
-
-
0002897393
-
Food phenolics: An overview
-
F. Shahidi, M. Naczk, Echnomic Publishing Company Inc Lancaster
-
F. Shahidi, and M. Naczk Food phenolics: an overview F. Shahidi, M. Naczk, Food Phenolics: Sources, Chemistry, Effects, Applications 1995 Echnomic Publishing Company Inc Lancaster 1 5
-
(1995)
Food Phenolics: Sources, Chemistry, Effects, Applications
, pp. 1-5
-
-
Shahidi, F.1
Naczk, M.2
-
48
-
-
77956882799
-
Nanocrystals: Industrially feasible multifunctional formulation technology for poorly soluble actives
-
R. Shegokar, and R.H. Müller Nanocrystals: Industrially feasible multifunctional formulation technology for poorly soluble actives Int. J. Pharm. 399 2010 129 139
-
(2010)
Int. J. Pharm.
, vol.399
, pp. 129-139
-
-
Shegokar, R.1
Müller, R.H.2
-
49
-
-
38549136863
-
Polyphenolic phytochemicals - Just antioxidants or much more?
-
DOI 10.1007/s00018-007-7237-1
-
D.E. Stevenson, and R.D. Hurst Polyphenolic phytochemicals - just antioxidants or much more? Cell. Mol. Life Sci. 64 2007 2900 2916 (Pubitemid 351152245)
-
(2007)
Cellular and Molecular Life Sciences
, vol.64
, Issue.22
, pp. 2900-2916
-
-
Stevenson, D.E.1
Hurst, R.D.2
-
50
-
-
0034955068
-
Itraconazole oral solution and intravenous formulations: A review of pharmacokinetics and pharmacodynamics
-
DOI 10.1046/j.1365-2710.2001.00338.x
-
L. Willems, R. van der Geest, and K. de Beule Itraconazole oral solution and intravenous formulations: a review of pharmacokinetics and pharmacodynamics J. Clin. Pharm. Ther. 26 2001 159 169 (Pubitemid 32592545)
-
(2001)
Journal of Clinical Pharmacy and Therapeutics
, vol.26
, Issue.3
, pp. 159-169
-
-
Willems, L.1
Van Der Geest, R.2
De Beule, K.3
-
51
-
-
0037151436
-
The development of an improved carrier system for sunscreen formulations based on crystalline lipid nanoparticles
-
S.A. Wissing, and R.H. Müller The development of an improved carrier system for sunscreen formulations based on crystalline lipid nanoparticles Int. J. Pharm. 242 2002 373 375
-
(2002)
Int. J. Pharm.
, vol.242
, pp. 373-375
-
-
Wissing, S.A.1
Müller, R.H.2
|