Bioproduction of cis-(1S,2R)-indandiol, a chiral pharmaceutical intermediate, using a solid-liquid two-phase partitioning bioreactor for enhanced removal of inhibitors

Journal of Chemical Technology and Biotechnology

Volumn 86, Issue 11, 2011, Pages 1379-1385

  Dafoe, Julian T S ^a   Daugulis, Andrew J ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Indandiol; Indene bioconversion; Polymer beads; Pseudomonas putida; Two phase partitioning bioreactor

Indexed keywords

INDANDIOL; INDENE BIOCONVERSION; POLYMER BEADS; PSEUDOMONAS PUTIDA; TWO PHASE PARTITIONING BIOREACTOR;

BACTERIA; BIOCONVERSION; BIOREACTORS; EMULSIFICATION; ORGANIC SOLVENTS; PHASE STABILITY; POLYMERS; PRODUCTIVITY; SILICONES; SUBSTRATES; TOXICITY;

LIQUIDS;

INDANDIOL; INDANONE DERIVATIVE; INDENE DERIVATIVE; ORGANIC SOLVENT; POLYMER; SILICONE OIL; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BIOCATALYSIS; BIOREACTOR; BIOTRANSFORMATION; CHEMICAL REACTION; CHIRALITY; CONTROLLED STUDY; IC 50; LIQUID; LIQUID LIQUID EXTRACTION; NONHUMAN; PSEUDOMONAS PUTIDA; SOLID; SOLID LIQUID TWO PHASE PARTITIONING BIOREACTOR; SOLUBILITY; TOXICITY TESTING;

PSEUDOMONAS PUTIDA;

EID: 80054122744     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.2653     Document Type: Article

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