Microbial Conversion of Indene to Indandiol: A Key Intermediate in the Synthesis of CRIXIVAN

Metabolic Engineering

Volumn 1, Issue 1, 1999, Pages 63-74

  Buckland, Barry C ^a   Drew, Stephen W ^a   Connors, Neal C ^a   Chartrain, Michel M ^a   Lee, Chanyong ^a   Salmon, Peter M ^a   Gbewonyo, Kodzo ^a   Zhou, Weichang ^a   Gailliot, Pat ^a   Singhvi, Rahul ^a   Olewinski Jr , Roger C ^a   Sun, Wen Jun ^a   Reddy, Jayanthi ^a   Zhang, Jinyou ^a   Jackey, Barbara A ^a   Taylor, Colleen ^a   Goklen, Kent E ^a   Junker, Beth ^a   Greasham, Randolph L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

AIDS; bio conversion; CRIXIVAN; indandiol; Indene; indinavir; Pseudomonas putida; Rhodococcus; toluene dioxygenase

Indexed keywords

INDAN DERIVATIVE; INDENE; INDENE DERIVATIVE; INDINAVIR; OXYGENASE; PROTEINASE INHIBITOR; TOLUENE DIOXYGENASE;

ARTICLE; DRUG DESIGN; GENETIC ENGINEERING; GENETICS; METABOLISM; PSEUDOMONAS PUTIDA;

DRUG DESIGN; GENETIC ENGINEERING; HIV PROTEASE INHIBITORS; INDANS; INDENES; INDINAVIR; OXYGENASES; PSEUDOMONAS PUTIDA;

EID: 0032600407     PISSN: 10967176     EISSN: None     Source Type: Journal    
DOI: 10.1006/mben.1998.0107     Document Type: Article

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