Mutation of pfm affects the adherence of Pseudomonas aeruginosa to host cells and the quorum sensing system

FEMS Microbiology Letters

Volumn 324, Issue 2, 2011, Pages 173-180

  Mou, Rui ^a   Bai, Fang ^a   Duan, Qiaonan ^a   Wang, Xuehan ^a   Xu, Haijin ^a   Bai, Yanling ^a   Zhang, Xiuming ^a   Jin, Shouguang ^a,b   Qiao, Mingqiang ^a  

^a NANKAI UNIVERSITY   (China)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Acyl homoserine lactones; Bacterial adherence; Enoyl CoA reductase

Indexed keywords

ELASTASE; LACTONE; N (3 OXODODECANOYL)HOMOSERINE LACTONE; N ACYLHOMOSERINE LACTONE; N BUTYRYL HOMOSERINE LACTONE; PYOCYANINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BIOSENSOR; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE MUTATION; HOST CELL; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NONHUMAN; PFM GENE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; WILD TYPE;

ANIMALS; BACTERIAL ADHESION; BACTERIAL PROTEINS; CAENORHABDITIS ELEGANS; CELL LINE; FATTY ACID DESATURASES; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MUTATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; QUORUM SENSING; VIRULENCE;

BACTERIA (MICROORGANISMS); CAENORHABDITIS ELEGANS; ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA;

EID: 80054119074     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2011.02401.x     Document Type: Article

References (37)

1. Bai F, Li YL, Xu HJ et al. (2007) Identification and functional characterization of pfm, a novel gene involved in swimming motility of Pseudomonas aeruginosa. Gene 401: 19-27.
2. Bell SC & Robinson PJ (2007) Exacerbations in cystic fibrosis: 2 center dot Prevention. Thorax 62: 723-732.
3. de Bentzmann S, Aurouze M, Ball G & Filloux A (2006) FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili. J Bacteriol 188: 4851-4860.
4. Dietrich LEP, Price-Whelan A, Petersen A, Whiteley M & Newman DK (2006) The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa. Mol Microbiol 61: 1308-1321.
5. Dobrindt U & Hacker J (2001) Whole genome plasticity in pathogenic bacteria. Curr Opin Microbiol 4: 550-557.
6. Essar DW, Eberly L, Hadero A & Crawford IP (1990) Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications. J Bacteriol 172: 884-900.
7. Fuqua C & Greenberg EP (1998) Self perception in bacteria: quorum sensing with acylated homoserine lactones. Curr Opin Microbiol 1: 183-189.
8. Hancock REW (1998) Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative gram-negative bacteria. Clin Infect Dis 27: S93-S99.
9. Hardalo C & Edberg SC (1997) Pseudomonas aeruginosa: assessment of risk from drinking water. Crit Rev Microbiol 23: 47-75.
10. Harrison F (2007) Microbial ecology of the cystic fibrosis lung. Microbiology 153: 917-923.
11. Heath RJ & Rock CO (1995) Enoyl-acyl carrier protein reductase (fabI) plays a determinant role in completing cycles of fatty acid elongation in Escherichia coli. J Biol Chem 270: 26538-26542.
12. Hoang TT & Schweizer HP (1999) Characterization of Pseudomonas aeruginosa Enoyl-Acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis. J Bacteriol 181: 5489-5497.
13. Kiratisin P, Tucker KD & Passador L (2002) LasR, a transcriptional activator of Pseudomonas aeruginosa virulence genes, functions as a multimer. J Bacteriol 184: 4912-4919.
14. Miller JH (1972) Experiments in molecular genetics, pp. 352-355. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
15. Mittal R, Sharma S, Chhibber S & Harjai K (2006) Contribution of quorum-sensing systems to virulence of Pseudomonas aeruginosa in an experimental pyelonephritis model. J Microbiol Immunol Infect 39: 302-309.
16. More MI, Finger LD, Stryker JL, Fuqua C, Eberhard A & Winans SC (1996) Enzymatic synthesis of a quorum-sensing autoinducer through use of defined substrates. Science 272: 1655-1658.
17. Ohman DE, Cryz SJ & Iglewski BH (1980) Isolation and characterization of Pseudomonas aeruginosa PAO mutant that produces altered elastase. J Bacteriol 142: 836-842.
18. Parsek MR & Greenberg EP (2000) Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms. P Natl Acad Sci USA 97: 8789-8793.
19. Pearson JP, Passador L, Iglewski BH & Greenberg EP (1995) A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. P Natl Acad Sci USA 92: 1490-1494.
20. Pearson JP, Pesci EC & Iglewski BH (1997) Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J Bacteriol 179: 5756-5767.
21. Pearson JP, Feldman M, Iglewski BH & Prince A (2000) Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection. Infect Immun 68: 4331-4334.
22. Pesci EC & Iglewski BH (1997) The chain of command in Pseudomonas quorum sensing. Trends Microbiol 5: 132-134; discussion 134-135.
23. Reimmann C, Ginet N, Michel L et al. (2002) Genetically programmed autoinducer destruction reduces virulence gene expression and swarming motility in Pseudomonas aeruginosa PAO1. Microbiology 148: 923-932.
24. Rumbaugh KP, Griswold JA & Hamood AN (1999) Contribution of the regulatory gene lasR to the pathogenesis of Pseudomonas aeruginosa infection of burned mice. J Burn Care Rehabil 20: 42-49.
25. Schaefer AL, Hanzelka BL, Parsek MR & Greenberg EP (2000) Detection, purification, and structural elucidation of the acylhomoserine lactone inducer of Vibrio fischeri luminescence and other related molecules. Methods in Enzymology 305: 288-301.
26. Schuster M, Lostroh CP, Ogi T & Greenberg EP (2003) Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J Bacteriol 185: 2066-2079.
27. Schweizer HP (1992) Allelic exchange in Pseudomonas aeruginosa using novel ColE1-type vectors and a family of cassettes containing a portable oriT and the counter-selectable Bacillus subtilis sacB marker. Mol Microbiol 6: 1195-1204.
28. Seed PC, Passador L & Iglewski BH (1995) Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy. J Bacteriol 177: 654-659.
29. Smith RS & Iglewski BH (2003) P. aeruginosa quorum-sensing systems and virulence. Curr Opin Microbiol 6: 56-60.
30. Smith RS, Harris SG, Phipps R & Iglewski B (2002) The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo. J Bacteriol 184: 1132-1139.
31. Stover CK, Pham XQ, Erwin AL et al. (2000) Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature 406: 959-964.
32. Tan MW, Mahajan-Miklos S & Ausubel FM (1999) Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. P Natl Acad Sci USA 96: 715-720.
33. Teasdale ME, Liu JY, Wallace J, Akhlaghi F & Rowley DC (2009) Secondary metabolites produced by the marine bacterium Halobacillus salinus that inhibit quorum sensing-controlled phenotypes in gram-negative bacteria. Appl Environ Microbiol 75: 567-572.
34. Van Delden C & Iglewski BH (1998) Cell-to-cell signaling and Pseudomonas aeruginosa infections. Emerg Infect Dis 4: 551-560.
35. Vanegas M, Correa N, Morales A, Martinez A, Rugeles L & Jimenez F (2009) Antibiotic resistance of bacteria isolated from biofilms in a food processing plant. Revista Mvz Cordoba 14: 1677-1683.
36. Wu H, Song ZJ, Hentzer M et al. (2000) Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa. Microbiology 146: 2481-2493.
37. Zhu L, Lin J, Ma J, Cronan JE & Wang H (2010) Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase. Antimicrob Agents Chemother 54: 689-698.