Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice

Journal of the Neurological Sciences

Volumn 310, Issue 1-2, 2011, Pages 90-95

  Szego, Éva M ^a   Gerhardt, Ellen ^a   Outeiro, Tiago F ^a   Kermer, Pawel ^a,b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

BDNF; Cholinergic; Dopamine; MPTP; Nucleus basalis magnocellularis; TrkB

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA SYNUCLEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLINE ACETYLTRANSFERASE; DOPAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEGENERATION; CELL DENSITY; CELL LOSS; CHOLINERGIC NERVE; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; WILD TYPE;

ACETYLCHOLINESTERASE; ALANINE; ALPHA-SYNUCLEIN; ANALYSIS OF VARIANCE; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC FIBERS; DISEASE MODELS, ANIMAL; DOPAMINE; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MPTP POISONING; MUTATION; NEURONS; PROLINE; PROTO-ONCOGENE PROTEINS; RECEPTOR, TRKB; TIME FACTORS;

EID: 80054111618     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2011.06.048     Document Type: Article

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