Benefits of Helicobacter pylori cagE genotyping in addition to cagA genotyping: A Bulgarian study

Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology

Volumn 100, Issue 4, 2011, Pages 529-535

  Boyanova, Lyudmila ^a   Yordanov, Daniel ^a   Gergova, Galina ^a   Markovska, Rumyana ^a   Mitov, Ivan ^a  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

Age; cagA; cagE; Gastritis; Gender; Genotype; H. pylori; Prevalence; Resistance; Sex; Ulcer

Indexed keywords

CLARITHROMYCIN; METRONIDAZOLE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM DETECTION; BULGARIA; CAGA GENE; CAGE GENE; CLINICAL ASSESSMENT; CONTROLLED STUDY; GENE FREQUENCY; GENETIC RECOMBINATION; GENETIC VARIABILITY; HELICOBACTER PYLORI; NONHUMAN; PEPTIC ULCER; PREVALENCE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; BULGARIA; CHILD; FEMALE; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

HELICOBACTER PYLORI;

EID: 80054109700     PISSN: 00036072     EISSN: 15729699     Source Type: Journal    
DOI: 10.1007/s10482-011-9608-8     Document Type: Article

References (35)

1. P Apostolopoulos I Vafiadis-Zouboulis M Tzivras D Kourtessas N Katsilambros A Archimandritis 2002 Helicobacter pylori (H. pylori) infection in Greece: the changing prevalence during a ten-year period and its antigenic profile BMC Gastroenterol 16 11 10.1186/1471-230X-2-11 (Pubitemid 38750990)
2. S Backert N Tegtmeyer M Selbach 2010 The versatility of Helicobacter pylori CagA effector protein functions: the master key hypothesis Helicobacter 15 163 176 20557357 10.1111/j.1523-5378.2010.00759.x 1:CAS:528: DC%2BC3cXotVejt7g%3D
3. K Baghaei L Shokrzadeh F Jafari H Dabiri Y Yamaoka M Bolfion H Zojaji MM Aslani MR Zali 2009 Determination of Helicobacter pylori virulence by analysis of the cag pathogenicity island isolated from Iranian patients Dig Liver Dis 41 634 638 19261552 10.1016/j.dld.2009.01.010 1:CAS:528:DC%2BD1MXhs1Sks7zM
4. L Boyanova G Gergova R Nikolov L Davidkov V Kamburov C Jelev I Mitov 2008 Prevalence and evolution of Helicobacter pylori resistance to 6 antibacterial agents over 12 years and correlation between susceptibility testing methods Diagn Microbiol Infect Dis 60 409 415 18248937 10.1016/j.diagmicrobio.2007.11. 008 1:CAS:528:DC%2BD1cXjsVSmsbY%3D (Pubitemid 351380781)
5. L Boyanova R Markovska D Yordanov M Marina K Ivanova S Panayotov G Gergova I Mitov 2009 High prevalence of virulent Helicobacter pylori strains in symptomatic Bulgarian patients Diagn Microbiol Infect Dis 64 374 380 19631090 10.1016/j.diagmicrobio.2009.04.005
6. L Boyanova D Yordanov G Gergova R Markovska I Mitov 2010 Association of iceA and babA genotypes in Helicobacter pylori strains with patient and strain characteristics Antonie Van Leeuwenhoek 98 343 350 20454856 10.1007/s10482-010- 9448-y 1:CAS:528:DC%2BC3cXhtFamtLjJ
7. N Broutet A Marais H Lamouliatte A de Mascarel R Samoyeau R Salamon F Mégraud 2001 cagA status and eradication treatment outcome of anti-Helicobacter pylori triple therapies in patients with nonulcer dyspepsia J Clin Microbiol 39 1319 1322 11283049 10.1128/JCM.39.4.1319-1322.2001 1:CAS:528:DC%2BD3MXjtlSltrc%3D (Pubitemid 32275428)
8. N Broutet S Tchamgoue E Pereira H Lamouliatte R Salamon F Mégraud 2003 Risk factors for failure of Helicobacter pylori therapy-results of an individual data analysis of 2751 patients Aliment Pharmacol Ther 17 99 109 12492738 10.1046/j.1365-2036.2003.01396.x 1:STN:280:DC%2BD3s%2FltFGlsg%3D%3D (Pubitemid 36140439)
9. V Caner M Yilmaz N Yonetci S Zencir N Karagenc I Kaleli H Bagci 2007 H. pylori iceA alleles are disease-specific virulence factors World J Gastroenterol 13 2581 2585 17552005 1:CAS:528:DC%2BD2sXns1artbw%3D (Pubitemid 46938827)
10. CLSI-National Committee for Clinical Laboratory Standards (2010). Performance standards for antimicrobial susceptibility testing. Twentieth informational supplement. Approved standard M100-S20, M7. CLSI, Wayne
11. SP Cole J Harwood R Lee R She DG Guiney 2004 Characterization of monospecies biofilm formation by Helicobacter pylori J Bacteriol 186 3124 3132 15126474 10.1128/JB.186.10.3124-3132.2004 1:CAS:528:DC%2BD2cXktVGhu70%3D (Pubitemid 38609756)
12. Y Erzin V Koksal S Altun A Dobrucali M Aslan S Erdamar A Dirican B Kocazeybek 2006 Prevalence of Helicobacter pylori vacA, cagA, cagE, iceA, babA2 genotypes and correlation with clinical outcome in Turkish patients with dyspepsia Helicobacter 11 574 580 17083380 10.1111/j.1523-5378.2006.00461.x 1:CAS:528:DC%2BD28XhtlensrjK (Pubitemid 44674143)
13. LB Feinstein RC Holman KL Yorita Christensen CA Steiner DL Swerdlow 2010 Trends in hospitalizations for peptic ulcer disease, United States, 1998-2005 Emerg Infect Dis 16 1410 1418 20735925 10.3201/eid1609.091126
14. LI Gomes GA Rocha AM Rocha TF Soares CA Oliveira PF Bittencourt DM Queiroz 2008 Lack of association between Helicobacter pylori infection with dupA-positive strains and gastroduodenal diseases in Brazilian patients Int J Med Microbiol 298 223 230 17897881 10.1016/j.ijmm.2007.05.006 1:CAS:528:DC%2BD1cXls1Churw%3D (Pubitemid 351318366)
15. T Ikenoue S Maeda K Ogura M Akanuma Y Mitsuno Y Imai H Yoshida Y Shiratori M Omata 2001 Determination of Helicobacter pylori virulence by simple gene analysis of the cag pathogenicity island Clin Diagn Lab Immunol 8 181 186 11139216 1:CAS:528:DC%2BD3MXmtVemsQ%3D%3D (Pubitemid 32061704)
16. A Jafarzadeh MT Rezayati M Nemati 2007 Specific serum immunoglobulin G to H. pylori and CagA in healthy children and adults (south-east of Iran) World J Gastroenterol 13 3117 3121 17589930 1:STN:280:DC%2BD2sznsFahuw%3D%3D (Pubitemid 47045472)
17. S Kato T Sugiyama M Kudo K Ohnuma K Ozawa K Iinuma M Asaka MJ Blaser 2000 CagA antibodies in Japanese children with nodular gastritis or peptic ulcer disease J Clin Microbiol 38 68 70 10618065 1:STN:280:DC%2BD3c%2FosFWisw%3D%3D (Pubitemid 30043266)
18. VP Lima MA Lima MV Ferreira MA Barros SH Rabenhorst 2010 The relationship between Helicobacter pylori genes cagE and virB11 and gastric cancer Int J Infect Dis 14 e613 e617 20106696 10.1016/j.ijid.2009.09.006 1:CAS:528: DC%2BC3cXhsF2qs7%2FF
19. F Megraud P Lehours 2007 Helicobacter pylori detection and antimicrobial susceptibility testing Clin Microbiol Rev 20 280 322 17428887 10.1128/CMR.00033-06 1:CAS:528:DC%2BD2sXlsFGmsbk%3D (Pubitemid 46709306)
20. LT Nguyen T Uchida K Murakami T Fujioka M Moriyama 2008 Helicobacter pylori virulence and the diversity of gastric cancer in Asia J Med Microbiol 57 1445 1453 19018013 10.1099/jmm.0.2008/003160-0 1:CAS:528:DC%2BD1MXhtVWru7s%3D
21. P Olbermann C Josenhans Y Moodley M Uhr C Stamer M Vauterin S Suerbaum M Achtman B Linz 2010 A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island PLoS Genet 6 e1001069 20808891 10.1371/journal.pgen.1001069
22. M Oleastro M Gerhard AI Lopes P Ramalho J Cabral A Sousa Guerreiro L Monteiro 2003 Helicobacter pylori virulence genotypes in Portuguese children and adults with gastroduodenal pathology Eur J Clin Microbiol Infect Dis 22 85 91 12627281 1:STN:280:DC%2BD3s7htlaqug%3D%3D (Pubitemid 36349969)
23. RP Podzorski DS Podzorski A Wuerth V Tolia 2003 Analysis of the vacA, cagA, cagE, iceA, and babA2 genes in Helicobacter pylori from sixty-one pediatric patients from the Midwestern United States Diagn Microbiol Infect Dis 46 83 88 12812722 10.1016/S0732-8893(03)00034-8 1:CAS:528:DC%2BD3sXksF2nt78%3D (Pubitemid 36703343)
24. JL Proença Módena AI Lopes Sales G Olszanski Acrani R Russo MA Vilela Ribeiro Y Fukuhara WD da Silveira JL Módena RB de Oliveira M Brocchi 2007 Association between Helicobacter pylori genotypes and gastric disorders in relation to the cag pathogenicity island Diagn Microbiol Infect Dis 59 7 16 17521839 10.1016/j.diagmicrobio.2007.03.019 (Pubitemid 47391170)
25. A Saha CE Hammond C Beeson RM Peek Jr AJ Smolka 2010 Helicobacter pylori represses proton pump expression and inhibits acid secretion in human gastric mucosa Gut 59 874 881 20581234 10.1136/gut.2009.194795 1:CAS:528: DC%2BC3cXhtVWmtLjK
26. Sharma SK, Maharjan DK, Thapa PB (2009) Hospital based analytic study of peptic ulcer disease in patients with dyspeptic symptoms. Kathmandu Univ Med J (KUMJ) 7: 135-138. http://www.kumj.com.np/ftp/issue/26/135-138.pdf
27. SI Smith KS Oyedeji AO Arigbabu F Cantet F Megraud OO Ojo AO Uwaifo JA Otegbayo SO Ola AO Coker 2004 Comparison of three PCR methods for detection of Helicobacter pylori DNA and detection of cagA gene in gastric biopsy specimens World J Gastroenterol 10 1958 1960 15222045 1:CAS:528:DC%2BD2cXmslWrtb8%3D (Pubitemid 39029301)
28. A Sokic-Milutinovic T Wex V Todorovic T Milosavljevic P Malfertheiner 2004 Anti-CagA and anti-VacA antibodies in Helicobacter pylori-infected patients with and without peptic ulcer disease in Serbia and Montenegro Scand J Gastroenterol 39 222 226 15074390 10.1080/00365520310008403 1:CAS:528: DC%2BD2cXjtFCntrY%3D (Pubitemid 38388865)
29. B Su PJ Ceponis PM Sherman 2003 Cytoskeletal rearrangements in gastric epithelial cells in response to Helicobacter pylori infection J Med Microbiol 52 861 867 12972579 10.1099/jmm.0.05229-0 (Pubitemid 37297314)
30. S Talarico BD Gold J Fero DT Thompson J Guarner S Czinn NR Salama 2009 Pediatric Helicobacter pylori isolates display distinct gene coding capacities and virulence gene marker profiles J Clin Microbiol 47 1680 1688 19386830 10.1128/JCM.00273-09 1:CAS:528:DC%2BD1MXosVejurc%3D
31. ML Tomasini S Zanussi M Sozzi R Tedeschi G Basaglia P De Paoli 2003 Heterogeneity of cag genotypes in Helicobacter pylori isolates from human biopsy specimens J Clin Microbiol 41 976 980 12624018 10.1128/JCM.41.3.976-980.2003 1:CAS:528:DC%2BD3sXisF2nu7c%3D (Pubitemid 36307095)
32. M Umeda N Murata-Kamiya Y Saito Y Ohba M Takahashi M Hatakeyama 2009 Helicobacter pylori CagA causes mitotic impairment and induces chromosomal instability J Biol Chem 284 22166 22172 19546211 10.1074/jbc.M109.035766 1:CAS:528:DC%2BD1MXpsFymtbw%3D
33. K Wallden A Rivera-Calzada G Waksman 2010 Type IV secretion systems: versatility and diversity in function Cell Microbiol 12 1203 1212 20642798 10.1111/j.1462-5822.2010.01499.x 1:CAS:528:DC%2BC3cXhtFSqtrbF
34. J Wang LJ van Doorn PA Robinson X Ji D Wang Y Wang L Ge JL Telford JE Crabtree 2003 Regional variation among vacA alleles of Helicobacter pylori in China J Clin Microbiol 41 1942 1945 12734231 10.1128/JCM.41.5.1942-1945.2003 1:CAS:528:DC%2BD3sXktlGrs70%3D (Pubitemid 36576517)
35. A Zullo F Perna C Hassan C Ricci I Saracino S Morini D Vaira 2007 Primary antibiotic resistance in Helicobacter pylori strains isolated in northern and central Italy Aliment Pharmacol Ther 25 1429 1434 17539982 10.1111/j.1365-2036. 2007.03331.x 1:STN:280:DC%2BD2szmtl2ltA%3D%3D (Pubitemid 46848887)