The use of molecular fluorescent markers to monitor absorption and distribution of xenobiotics in a silkworm model

Biomaterials

Volumn 32, Issue 36, 2011, Pages 9576-9583

  Tansil, Natalia C ^a   Li, Yang ^b   Koh, Leng Duei ^b   Peng, Teng Choon ^a   Win, Khin Yin ^a   Liu, Xiang Yang ^b   Han, Ming Yong ^a,b  

^a INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

ADME; Silk; Tissue engineering; Xenobiotic

Indexed keywords

ADME; ANIMAL MODEL; BIOLOGICAL PROCESS; FLUORESCENT COMPOUNDS; FLUORESCENT MARKERS; IN-VIVO; LIVING ORGANISMS; MOLECULAR PROPERTIES; SPECIFIC MATERIALS; STIMULI-SENSITIVE; TISSUE ENGINEERING APPLICATIONS; XENOBIOTIC;

ABSORPTION; BIOCHEMISTRY; FLUORESCENCE; PHYSIOLOGY; SCAFFOLDS (BIOLOGY); SILK; TISSUE;

ANIMALS;

RHODAMINE B; XENOBIOTIC AGENT;

ABSORPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DRUG UPTAKE; EXCRETION; FLUORESCENCE; LUMINESCENCE; NONHUMAN; PRIORITY JOURNAL; SILK; SILKWORM; TISSUE DISTRIBUTION; XENOBIOTIC METABOLISM;

ABSORPTION; ACRIDINE ORANGE; ANIMAL STRUCTURES; ANIMALS; BIOLOGICAL MARKERS; BOMBYX; CELL LINE, TUMOR; FLUORESCENT DYES; GREEN FLUORESCENT PROTEINS; HUMANS; OVUM; RHODAMINES; TISSUE DISTRIBUTION; TISSUE SCAFFOLDS; XENOBIOTICS;

ANIMALIA; BOMBYX MORI;

EID: 80054078452     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.08.081     Document Type: Article

References (16)

1. Tansil N.C., Li Y., Teng C.P., Zhang S.Y., Khin Y.W., Chen X., et al. Intrinsically colored and luminescent silk. Adv Mater 2011, 23:1463-1466.
2. Shao Z.Z., Vollrath F. Materials: surprising strength of silkworm silk. Nature 2001, 418:741.
3. Altman G.H., Diaz F., Jakuba C., Calabro T., Horan R.L., Chen J.S., et al. Silk based biomaterials. Biomaterials 2003, 24:401-416.
4. Hino R., Tomita M., Yoshizato K. The generation of germline transgenic silkworms for the production of biologically active recombinant fusion proteins of fibroin and human basic fibroblast growth factor. Biomaterials 2006, 27:5715-5724.
5. Benfenati V., Toffanin S., Capelli R., Camassa L.M.A., Ferroni S., Kaplan D.L., et al. A silk platform that enables electrophysiology and targeted drug delivery in brain astroglial cells. Biomaterials 2010, 31:7883-7891.
6. Bray L.J., George K.A., Ainscough S.L., Hutmacher D.W., Chirila T.V., Harkin D.G. Human corneal epithelial equivalents constructed on Bombyx mori silk fibroin membranes. Biomaterials 2011, 32:5086-5091.
7. Tan Pamela H.S., Aung K.Z., Toh S.L., Goh J.C.H., Nathan S.S. Three-dimensional porous silk tumor constructs in the approximation of in vivo osteosarcoma physiology. Biomaterials 2011, 32:6131-6137.
8. Selwyn J.E., Steinfeld J.I. Aggregation equilibria of xanthenes dyes. J Phys Chem 1972, 76:762-774.
9. Antonov L., Gergov G., Petrov V., Kubista M., Nygren J. UV-Vis spectroscopic and chemometric study on the aggregation of ionic dyes in water. Talanta 1999, 49:99-106.
10. Aruga H. Principles of sericulture 1994, A.A. Balkema, Rotterdam, p. 133-264.
11. Kuriyama K., Eguchi M. Conversion of the molecular-form by alkaline treatment of gut protease from the silkworm, Bomboyx mori. Comp Biochem Physiol B 1985, 82:575-579.
12. Segalat L. Invertebrate animal models of diseases as screening tools in drug discovery. ACS Chem Biol 2007, 2:231-236.
13. Tampakakis E., Okoli I., Mylonakis E. A C. elegans-based, whole animal, in vivo screen for the identification of antifungal compounds. Nat Protocol 2008, 3:1925-1931.
14. Lieschke G.J., Currie P.D. Animal models of human disease: zebrafish swim into view. Nat Rev Genet 2007, 8:353-367.
15. Lipinski C. Drug solubility in water and dimethylsulfoxide. Molecular drug properties 2008, Wiley-VCH, Weinheim. R. Mannhold (Ed.).
16. Edwards E.W., Chanana M., Wang D., Möhwald H. Stimuli-responsive reversible transport of nanoparticles across water/oil interfaces. Angew Chem Int Ed 2008, 47:320-323.