Epidermal growth factor receptor tyrosine kinase regulates the human inward rectifier potassium K IR2.3 channel, stably expressed in HEK 293 cells

British Journal of Pharmacology

Volumn 164, Issue 5, 2011, Pages 1469-1478

  Zhang, De Yong ^a   Zhang, Yan Hui ^a   Sun, Hai Ying ^a   Lau, Chu Pak ^a   Li, Gui Rong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

EGFR tyrosine kinase; inward rectifier K + channels; protein tyrosine kinase; protein tyrosine phosphatase; tyrosine phosphorylation

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; GENISTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.3; N (4 BUTYLPHENYL) ALPHA CYANOCAFFEIC ACID AMIDE; ORTHOVANADIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE; GENE EXPRESSION; GENETIC STABILITY; HUMAN; HUMAN CELL; KIR2.3 GENE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; UPREGULATION;

BLOTTING, WESTERN; ELECTROPHYSIOLOGY; GENISTEIN; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PLASMIDS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN KINASE INHIBITORS; PROTEIN TYROSINE PHOSPHATASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; TYRPHOSTINS; VANADATES;

EID: 80054043745     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01424.x     Document Type: Article

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