Human Kir2.1 channel carries a transient outward potassium current with inward rectification

Pflugers Archiv European Journal of Physiology

Volumn 457, Issue 6, 2009, Pages 1275-1285

  Zhang, De Yong ^a   Lau, Chu Pak ^b   Li, Gui Rong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

I K1; Inward rectification; Kir2.1 channel; Transient outward current with inward rectification

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; MAGNESIUM; SPERMINE;

ACTION POTENTIAL; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL STRAIN HEK293; CONTROLLED STUDY; GENE INACTIVATION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTION POTENTIALS; CELL LINE; HUMANS; KIDNEY; MAGNESIUM; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; SPERMINE;

EID: 62549112999     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-008-0608-0     Document Type: Article

References (47)

1. DM Barry JM Nerbonne 1996 Myocardial potassium channels: electrophysiological and molecular diversity Annu Rev Physiol 58 363 394
2. + currents in isolated human ventricular myocytes from patients with terminal heart failure Circ Res 73 379 385
3. + current in isolated adult rat atrial myocytes Am J Physiol Heart Circ Physiol 260 H1236 H1247
4. DL Campbell Y Qu RL Rasmusson HC Strauss 1993 The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes. II. Closed state reverse use- dependent block by 4-aminopyridine J Gen Physiol 101 603 626
5. W Chen C Steenbergen LA Levy J Vance RE London E Murphy 1996 Measurement of free Ca2+ in sarcoplasmic reticulum in perfused rabbit heart loaded with 1,2-bis(2-amino-5,6-difluorophenoxy)ethane-N,N,N',N'-tetraacetic acid by 19F NMR J Biol Chem 271 7398 7403
6. E Coraboeuf E Carmeliet 1982 Existence of two transient outward currents in sheep cardiac Purkinje fibers Pflugers Arch 392 352 359
7. K1) controls cardiac excitability and is involved in arrhythmogenesis Heart Rhythm 2 316 324
8. + current Circ Res 94 1332 1339
9. MQ Dong CP Lau Z Gao GN Tseng GR Li 2006 Characterization of recombinant human cardiac KCNQ1/KCNE1 channels (I (Ks)) stably expressed in HEK 293 cells J Membr Biol 210 183 192
10. + dependence J Physiol (Lond) 435 395 420
11. E Ficker M Taglialatela BA Wible CM Henley AM Brown 1994 Spermine and spermidine as gating molecules for inward rectifier K channels Science 266 1068 1072
12. Z Gao HY Sun CP Lau FP Chin-Wan GR Li 2007 Evidence for cystic fibrosis transmembrane conductance regulator chloride current in swine ventricular myocytes J Mol Cell Cardiol 42 98 105
13. WR Giles AC van Ginneken 1985 A transient outward current in isolated cells from the crista terminalis of rabbit heart J Physiol (Lond) 368 243 264
14. JP Headrick RJ Willis 1991 Cytosolic free magnesium in stimulated, hypoxic, and underperfused rat heart J Mol Cell Cardiol 23 991 999
15. + current in guinea-pig cardiac myocytes J Physiol (Lond) 419 297 320
16. B Jiang X Sun K Cao R Wang 2002 Endogenous Kv channels in human embryonic kidney (HEK-293) cells Mol Cell Biochem 238 69 79
17. IR Josephson J Sanchez-Chapula AM Brown 1984 Early outward current in rat single ventricular cells Circ Res 54 157 162
18. JL Kenyon WR Gibbons 1979 4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers J Gen Physiol 73 139 157
19. GR Li J Feng Z Wang B Fermini S Nattel 1995 Comparative mechanisms of 4-aminopyridine-resistant Ito in human and rabbit atrial myocytes Am J Physiol 269 H463 H472
20. GR Li CP Lau TK Leung S Nattel 2004 Ionic current abnormalities associated with prolonged action potentials in cardiomyocytes from diseased human right ventricles Heart Rhythm 1 460 468
21. GR Li H Sun J To HF Tse CP Lau 2004 Demonstration of calcium-activated transient outward chloride current and delayed rectifier potassium currents in Swine atrial myocytes J Mol Cell Cardiol 36 495 504
22. Ca contributes to rate-dependent changes of action potentials in human ventricular myocytes Am J Physiol Circ Physiol 276 H98 H106
23. to1 in myocytes isolated from the human right ventricle Am J Physiol Heart Circ Physiol 275 H369 H377
24. + current in human ventricular myocytes Circ Res 78 689 696
25. + current with inward rectification in canine ventricular myocytes Am J Physiol Cell Physiol 274 C577 C585
26. + current in guinea pig cardiac myocytes Am J Physiol Heart Circ Physiol 279 H130 H138
27. + current in cardiac ventricular myocytes Am J Physiol Heart Circ Physiol 266 H1286 H1299
28. K1 in cat and guinea-pig cardiac ventricular myocytes J Mol Cell Cardiol 27 673 691
29. + channel, Kir2.1 J Physiol (Lond) 548 361 371
30. 2+ Nature 325 156 159
31. J Maylie M Morad 1984 A transient outward current related to calcium release and development of tension in elephant seal atrial fibres J Physiol (Lond) 357 267 292
32. E Murphy C Steenbergen LA Levy B Raju RE London 1989 Cytosolic free magnesium levels in ischemic rat heart J Biol Chem 264 5622 5627
33. CG Nichols EN Makhina WL Pearson Q Sha AN Lopatin 1996 Inward Rectification and Implications for Cardiac Excitability Circ Res 78 1 7
34. D Noble 1984 The surprising heart: a review of recent progress in cardiac electrophysiology J Physiol 353 1 50
35. KF Raab-Graham CM Radeke CA Vandenberg 1994 Molecular cloning and expression of a human heart inward rectifier potassium channel Neuroreport 5 2501 2505
36. + current. Differential sensitivity to block by class III antiarrhythmic agents J Gen Physiol 96 195 215
37. Y Shimoni RB Clark WR Giles 1992 Role of an inwardly rectifying potassium current in rabbit ventricular action potential J Physiol 448 709 727
38. 2+ J Gen Physiol 96 109 133
39. Q Tang MW Jin JZ Xiang MQ Dong HY Sun CP Lau GR Li 2007 The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go-related gene potassium channels stably expressed in HEK 293 cells Biochem Pharmacol 74 1596 1607
40. GN Tseng BF Hoffman 1989 Two components of transient outward current in canine ventricular myocytes Circ Res 64 633 647
41. + current and phase 0 of the action potential in isolated cardiac myocytes Circ Res 75 491 502
42. LH Xie SA John JN Weiss 2002 Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block J Gen Physiol 120 53 66
43. L Yue J Feng GR Li S Nattel 1996 Characterization of an ultrarapid delayed rectifier potassium channel involved in canine atrial repolarization J Physiol (Lond) 496 647 662
44. L Yue J Feng GR Li S Nattel 1996 Transient outward and delayed rectifier currents in canine atrium: properties and role of isolation methods Am J Physiol Heart Circ Physiol 270 H2157 H2168
45. JJ Zaritsky JB Redell BL Tempel TL Schwarz 2001 The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes J Physiol 533 697 710
46. + solution Am J Physiol Cell Physiol 287 C1396 C1403
47. AC Zygmunt WR Gibbons 1992 Properties of the calcium-activated chloride current in heart J Gen Physiol 99 391 414