Molecular basis for genistein-induced inhibition of Kir2.3 currents

Pflugers Archiv European Journal of Physiology

Volumn 456, Issue 2, 2008, Pages 413-423

  Zhao, Zhiying ^a   Liu, Boyi ^a   Zhang, Guohong ^a   Jia, Zhanfeng ^a   Jia, Qingzhong ^a   Geng, Xian ^a   Zhang, Hailin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Inhibition; Inward rectifier potassium channel; Ion channel modulation; Phospholipid; Voltage clamp; Xenopus laevis

Indexed keywords

DAIDZEIN; GENISTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.3; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3.4; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN CELL; INHIBITION KINETICS; MEMBRANE CHANNEL; MOLECULAR DYNAMICS; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; VOLTAGE CLAMP; XENOPUS;

ANIMALS; CELL LINE; ENZYME INHIBITORS; FEMALE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENISTEIN; HUMANS; ISOFLAVONES; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN KINASE INHIBITORS; TRANSFECTION; TYRPHOSTINS; XENOPUS LAEVIS;

EID: 42049102812     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0391-3     Document Type: Article

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