Antiulcer potential of Rubia cordifolia Linn. in experimental animals

International Journal of Green Pharmacy

Volumn 5, Issue 2, 2011, Pages 149-154

  Kalra, Pankaj ^a   Datusalia, Ashok Kumar ^a   Sharma, Sunil ^a  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Alcoholic extract; Antiulcerogenic activity; Rubia cordifolia Linn

Indexed keywords

ALCOHOL; ANTIULCER AGENT; CARBOHYDRATE; IBUPROFEN; PEPSIN A; PLANT EXTRACT; PROTEIN; RANITIDINE; RUBIA CORDIFOLIA EXTRACT; UNCLASSIFIED DRUG;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLD SENSITIVITY; CONTROLLED STUDY; FEMALE; MALE; NONHUMAN; RAT; RUBIA CORDIFOLIA; STOMACH CONTENT; STOMACH ULCER; STOMACH VOLUME;

EID: 80054041960     PISSN: 09738258     EISSN: 19984103     Source Type: Journal    
DOI: 10.4103/0973-8258.85182     Document Type: Article

References (36)

1. Alkofahi A, Atta AH. Pharmacological screening of the antiulcerogenic effects of some Jordanian medicinal plants in rats. J Ethnopharmacol 1999;67:341-4.
2. Peskar BM, Maricic N. Role of prostaglandins in gastroprotection. Dig Dis Sci 1998;43(9 Suppl):23S-29S. (Pubitemid 28433945)
3. Konturek PC, Brzowski T, Sliwowski Z, Pajido R, Stachura J, Hahn EG, et al. Involvement of nitric oxide and prostaglandins in gastroprotection induced by bacterial lipopolysaccharide. Scand. J Gastroenterol 1998;33:691-700. (Pubitemid 28358051)
4. Ariyphisi I, Toshiharu A, Sugimura F, Abe M, Matsuo Y, Honda T. Recurrence during maintenance therapy with histamine H2 receptors antagonist in cases of gastric ulcers. Nikon Univ J Med 1986;28:69.
5. Hiruma-Lima CA, Gracioso JS, Toma W, Almeida AB, Paula AC, Brasil DS, et al. Gastroprotective effect of aparisthman, a diterpene isolated from Aparisthmium cordatum, on experimental gastric ulcer models in rats and mice. Phytomedicine 2001;8:94-100. (Pubitemid 32267091)
6. Gracioso JS, Hiruma-Lima CA, Souza Brito AR. Antiulcerogenic effect of a hydroalcoholic extract and its organic fractions of Neurolaena lobata (L.) R. Br. Phytomedicine 2000;7:283-9. (Pubitemid 30618492)
7. Hiruma-Lima CA, Gracioso JS, Bighetti EJ, Grassi- Kassisse DM, Nunes DS, Souza Brito AR. Effect of essential oil obtained from Croton cajucara Benth. on gastric ulcer healing and protective factors of the gastric mucosa. Phytomedicine 2002;9:523-9.
8. Antakar DS, Chintwala T, Bhatt N. Anti-inflammatory activiy of Rubia cordifolia Linn. in rats. Indian J Pharmacol 1983;15:185-8.
9. Joharapurkar AA, Deode NM, Zambad SP, Umathe SN. Immunomodulatory activity of alcoholic extract of Rubia cordifolia Linn. Indian Drugs 2003;40:179.
10. Kasture VS, Deshmukh VK, Chopde CT. Anticonvulsant and behavioral actions of triterpene isolated from Rubia cordifolia. Indian J Exp Biol 2000;38:675-80.
11. Adwankar MK, Chitnis MP. In vivo anti-cancer acivity of RC-80, a plant isolate from Rubia cordifolia Linn., against a spectrum tumour models. Chemotherapy 1982;28:291-3. (Pubitemid 12093821)
12. Itokawa H, Qiao YF, Takeya K, Iitaka Y. New triterpenoids from Rubia cordifolia var. pratensis (Rubiaceae). Chem Pharm Bull 1989;37:1670.
13. Mhaskar KS, Blatter E, Caius JF. Indian Medicinal plants - Their usage in Ayurveda and Unani Medicine. 2000;3.
14. Suleyman H, Demirezer LO, Buyukokuroglu ME, Akcay MF, Gepdiremen A, Banoglu ZN, et al. Antiulcerogenic effect of Hippophae rhamnoides L. Phytother Res 2001;15:625-7.
15. Suleyman H, Demirezer LO, Kuruuzum-Uz A. Effects of Rumex patientia root extract on indomethacin and ethanol induced gastric damage in rats. Pharmazie 2004;59:147-9. (Pubitemid 38222487)
16. Parmar NS, Desai JK. A review of the current methodology for the evaluation of gastric and duodenal anti-ulcer agents. Indian J Pharmacol 1993;25:120.
17. Shay H, Komarov SA, Fels SS, Meranze D, Gruenstein M, Siplet H. A simple method for the uniform production of gastric ulceration. Gastroenterol 194;55:43-61.
18. Goel RK, Bhattacharya SK. Gastroduodenal mucosal defense and mucosal protective agents. Indian J Exp Biol 1991;29:701-14.
19. Prino G, Paglialunga S, Nardi G, Lietti A. Inhibition of experimentally induced gastric ulcers in the rat by a new sulfated glycopeptides. Eur J Pharmacol 1971;15:119-26.
20. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin-Phenol reagent. J Biol Chem 1951;193:265-75.
21. Goel RK, Chakrabarti A, Sanyal AK. The effect of biological variables on the anti-ulcerogenic effect of vegetable plantain banana. Planta Med 1985;2:85-8. (Pubitemid 15117672)
22. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8. (Pubitemid 9194347)
23. Kayali RC, Akatay U, Akcay T, Altuǧ T. Effect of alpha-lipoic acid supplementation on markers of protein oxidation in post-mitotic tissue of ageing rat. Cell Biochem Funct 2006;24:79-85. (Pubitemid 43171011)
24. Srivastava SK, Nath C, Gupta MB, Vrat S, Sinha NJ, Dhawan NK, et al. Protection against gastric ulcer by verapamil. Pharmacol Res 1991;23:81-6.
25. Sanyal AK, Mitra PK, Goel RK. A modified method to estimate dissolved mucosubstances in gastric juice. Indian J Exp Biol 1983;21:78-80.
26. Flemstrong G, Garner A. Gastroduodenal HCO3 transport: Characteristics and proposed role in acidity regulation and mucosal protection. Am J Physiol 1982;242:153-93.
27. Zalewsky CA, Moody FG. Mechanisms of mucus release in exposed canine gastric mucosa. Gastroenterol 1979;77:719-29. (Pubitemid 9235788)
28. Goel RK, Maiti RN, Mukhopadhyaya K. Effect of Tamrabhasma, an indigenous preparation of copper on rat gastric mucosal resistance. Indian J Exp Biol 1994;32:559-61. (Pubitemid 24261485)
29. Djahanguiri B, Taubin HL, Landsburg L. Increased sympathetic activity in the pathogenesis of restraint ulcer in rats. J Pharmacol Exp Ther 1973;184:163-8.
30. Miller TA, Henagan JM. Indomethacin decreases resistance of gastric barrier to disruption by alcohol. Dig Dis Sci 1984;29:141-9. (Pubitemid 14189015)
31. Hollander D, Tarnawski A, Gergely H, Zipser RD. Sucralfate protection of the gastric mucosa against ethanol-induced injury: A prostaglandin-mediated process. Scand J Gastroenterol 1984;19:97-102. (Pubitemid 14075556)
32. Hunt HR, Cederberg C, Dent J, Halter F, Howden C, Marks IN, et al. Optimizing acid suppression for treatment of acid-related diseases. Dig Dis Sci 1995;40:24s-49s.
33. Wolfe M, Sachs G. Acid suppression: Optimizing therapy for gastroduodenal ulcer healing, gastroesophageal reflux disease, and stress-related erosive syndrome. Gastroenterol 2000;118(2 Suppl 1):S9-31. (Pubitemid 30094433)
34. Scheiman JM, Dubois RN, Giardiello FM. NSAIDs, Eicosonoids, and the Gastroenteric Tract. Vol. 25. Philadelphia: Saunders; 1996. p. 279-89.
35. Patil RA, Jagdale SC, Kasture SB. Antihyperglycemic, antistress and nootropic activity of roots of Rubia cordifoia Linn. Indian J Exp Biol 2006;44:987-92. (Pubitemid 46797004)
36. Miller TA. Mechanisms of stress-related mucosal damage. Am J Med 1987;83(6A):8-14.