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Volumn 41, Issue 11, 2011, Pages 1609-1621

The neuropeptide calcitonin gene-related peptide affects allergic airway inflammation by modulating dendritic cell function

Author keywords

Allergic asthma; Calcitonin gene related peptide; Dendritic cells; Neuro immune interactions; Sensory nerves

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE RELATED PEPTIDE[8-37]; CYTOKINE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OVALBUMIN;

EID: 80054025175     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03822.x     Document Type: Article
Times cited : (72)

References (60)
  • 1
    • 47949119866 scopus 로고    scopus 로고
    • Pathogenesis of asthma
    • Holgate ST. Pathogenesis of asthma. Clin Exp Allergy 2008; 38:872-97.
    • (2008) Clin Exp Allergy , vol.38 , pp. 872-897
    • Holgate, S.T.1
  • 4
    • 0032522829 scopus 로고    scopus 로고
    • Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice
    • Lambrecht BN, Salomon B, Klatzmann D, Pauwels RA. Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice. J Immunol 1998; 160:4090-7.
    • (1998) J Immunol , vol.160 , pp. 4090-4097
    • Lambrecht, B.N.1    Salomon, B.2    Klatzmann, D.3    Pauwels, R.A.4
  • 5
    • 17144367365 scopus 로고    scopus 로고
    • In vivo depletion of lung CD11c+dendritic cells during allergen challenge abrogates the characteristic features of asthma
    • van Rijt LS, Jung S, Kleinjan Aet al. In vivo depletion of lung CD11c+dendritic cells during allergen challenge abrogates the characteristic features of asthma. J Exp Med 2005; 201:981-91.
    • (2005) J Exp Med , vol.201 , pp. 981-991
    • van Rijt, L.S.1    Jung, S.2    Kleinjan, A.3
  • 6
    • 0035126782 scopus 로고    scopus 로고
    • Neurogenic inflammation in the airways
    • Barnes PJ. Neurogenic inflammation in the airways. Respir Physiol 2001; 125:145-54.
    • (2001) Respir Physiol , vol.125 , pp. 145-154
    • Barnes, P.J.1
  • 7
    • 70449519959 scopus 로고    scopus 로고
    • Modulation of sensory nerve function and the cough reflex: understanding disease pathogenesis
    • Nasra J, Belvisi MG. Modulation of sensory nerve function and the cough reflex: understanding disease pathogenesis. Pharmacol Ther 2009; 124:354-75.
    • (2009) Pharmacol Ther , vol.124 , pp. 354-375
    • Nasra, J.1    Belvisi, M.G.2
  • 9
    • 0037299013 scopus 로고    scopus 로고
    • Sensory nerves and airway inflammation: role of A delta and C-fibres
    • Belvisi MG. Sensory nerves and airway inflammation: role of A delta and C-fibres. Pulmon Pharmacol Ther 2003; 16:1-7.
    • (2003) Pulmon Pharmacol Ther , vol.16 , pp. 1-7
    • Belvisi, M.G.1
  • 10
    • 0022578896 scopus 로고
    • Asthma as an axon reflex
    • Barnes PJ. Asthma as an axon reflex. Lancet 1986; 1:242-5.
    • (1986) Lancet , vol.1 , pp. 242-245
    • Barnes, P.J.1
  • 11
    • 0034730572 scopus 로고    scopus 로고
    • Excitatory non-adrenergic-non-cholinergic neuropeptides: key players in asthma
    • Kraneveld AD, James DE, de Vries A, Nijkamp FP. Excitatory non-adrenergic-non-cholinergic neuropeptides: key players in asthma. Eur J Pharmacol 2000; 405:113-29.
    • (2000) Eur J Pharmacol , vol.405 , pp. 113-129
    • Kraneveld, A.D.1    James, D.E.2    de Vries, A.3    Nijkamp, F.P.4
  • 12
    • 0028567676 scopus 로고
    • Low plasma concentrations of VIP and elevated levels of other neuropeptides during exacerbations of asthma
    • Cardell LO, Uddman R, Edvinsson L. Low plasma concentrations of VIP and elevated levels of other neuropeptides during exacerbations of asthma. Eur Respir J 1994; 7:2169-73.
    • (1994) Eur Respir J , vol.7 , pp. 2169-2173
    • Cardell, L.O.1    Uddman, R.2    Edvinsson, L.3
  • 13
    • 0026730784 scopus 로고
    • Substance P and beta-endorphin-like immunoreactivity in lavage fluids of subjects with and without allergic asthma
    • Nieber K, Baumgarten CR, Rathsack R, Furkert J, Oehme P, Kunkel G. Substance P and beta-endorphin-like immunoreactivity in lavage fluids of subjects with and without allergic asthma. J Allergy Clin Immunol 1992; 90:646-52.
    • (1992) J Allergy Clin Immunol , vol.90 , pp. 646-652
    • Nieber, K.1    Baumgarten, C.R.2    Rathsack, R.3    Furkert, J.4    Oehme, P.5    Kunkel, G.6
  • 14
    • 0028931315 scopus 로고
    • Elevated substance P content in induced sputum from patients with asthma and patients with chronic bronchitis
    • Tomaki M, Ichinose M, Miura Met al. Elevated substance P content in induced sputum from patients with asthma and patients with chronic bronchitis. Am J Respir Crit Care Med 1995; 151:613-7.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 613-617
    • Tomaki, M.1    Ichinose, M.2    Miura, M.3
  • 15
    • 3142700274 scopus 로고    scopus 로고
    • Temporal and spatial distribution of VIP, CGRP and their receptors in the development of airway hyper responsiveness in the lungs
    • Ren YH, Qin XQ, Guan CX, Luo ZQ, Zhang CQ, Sun XH. Temporal and spatial distribution of VIP, CGRP and their receptors in the development of airway hyper responsiveness in the lungs. Sheng Li Xue Bao 2004; 56:137-46.
    • (2004) Sheng Li Xue Bao , vol.56 , pp. 137-146
    • Ren, Y.H.1    Qin, X.Q.2    Guan, C.X.3    Luo, Z.Q.4    Zhang, C.Q.5    Sun, X.H.6
  • 16
    • 21844455801 scopus 로고    scopus 로고
    • Allergic airway inflammation induces tachykinin peptides expression in vagal sensory neurons innervating mouse airways
    • Dinh QT, Mingomataj E, Quarcoo Det al. Allergic airway inflammation induces tachykinin peptides expression in vagal sensory neurons innervating mouse airways. Clin Exp Allergy 2005; 35:820-5.
    • (2005) Clin Exp Allergy , vol.35 , pp. 820-825
    • Dinh, Q.T.1    Mingomataj, E.2    Quarcoo, D.3
  • 17
    • 0029811247 scopus 로고    scopus 로고
    • Induction of tachykinin gene and peptide expression in guinea pig nodose primary afferent neurons by allergic airway inflammation
    • Fischer A, McGregor GP, Saria A, Philippin B, Kummer W. Induction of tachykinin gene and peptide expression in guinea pig nodose primary afferent neurons by allergic airway inflammation. J Clin Invest 1996; 98:2284-91.
    • (1996) J Clin Invest , vol.98 , pp. 2284-2291
    • Fischer, A.1    McGregor, G.P.2    Saria, A.3    Philippin, B.4    Kummer, W.5
  • 18
    • 34247265934 scopus 로고    scopus 로고
    • Airway expression of calcitonin gene-related peptide in T-cell peptide-induced late asthmatic reactions in atopics
    • Kay AB, Ali FR, Heaney LGet al. Airway expression of calcitonin gene-related peptide in T-cell peptide-induced late asthmatic reactions in atopics. Allergy 2007; 62:495-503.
    • (2007) Allergy , vol.62 , pp. 495-503
    • Kay, A.B.1    Ali, F.R.2    Heaney, L.G.3
  • 19
    • 33747172224 scopus 로고    scopus 로고
    • The contribution of neurotrophins to the pathogenesis of allergic asthma
    • Rochlitzer S, Nassenstein C, Braun A. The contribution of neurotrophins to the pathogenesis of allergic asthma. Biochem Soc Trans 2006; 34:594-9.
    • (2006) Biochem Soc Trans , vol.34 , pp. 594-599
    • Rochlitzer, S.1    Nassenstein, C.2    Braun, A.3
  • 20
    • 64249105703 scopus 로고    scopus 로고
    • The role of neuro-immune cross-talk in the regulation of inflammation and remodelling in asthma
    • Veres TZ, Rochlitzer S, Braun A. The role of neuro-immune cross-talk in the regulation of inflammation and remodelling in asthma. Pharmacol Ther 2009; 122:203-14.
    • (2009) Pharmacol Ther , vol.122 , pp. 203-214
    • Veres, T.Z.1    Rochlitzer, S.2    Braun, A.3
  • 21
    • 35848933259 scopus 로고    scopus 로고
    • Spatial interactions between dendritic cells and sensory nerves in allergic airway inflammation
    • Veres TZ, Rochlitzer S, Shevchenko Met al. Spatial interactions between dendritic cells and sensory nerves in allergic airway inflammation. Am J Respir Cell Mol Biol 2007; 37:553-61.
    • (2007) Am J Respir Cell Mol Biol , vol.37 , pp. 553-561
    • Veres, T.Z.1    Rochlitzer, S.2    Shevchenko, M.3
  • 22
    • 62549114847 scopus 로고    scopus 로고
    • Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation
    • Veres TZ, Shevchenko M, Krasteva Get al. Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation. Am J Pathol 2009; 174:808-17.
    • (2009) Am J Pathol , vol.174 , pp. 808-817
    • Veres, T.Z.1    Shevchenko, M.2    Krasteva, G.3
  • 23
    • 2342575610 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide: role in airway homeostasis
    • Dakhama A, Larsen GL, Gelfand EW. Calcitonin gene-related peptide: role in airway homeostasis. Curr Opin Pharmacol 2004; 4:215-20.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 215-220
    • Dakhama, A.1    Larsen, G.L.2    Gelfand, E.W.3
  • 24
    • 0036671940 scopus 로고    scopus 로고
    • Interaction of calcitonin-gene-related peptide with its receptors
    • Conner AC, Hay DL, Howitt SGet al. Interaction of calcitonin-gene-related peptide with its receptors. Biochem Soc Trans 2002; 30:451-5.
    • (2002) Biochem Soc Trans , vol.30 , pp. 451-455
    • Conner, A.C.1    Hay, D.L.2    Howitt, S.G.3
  • 26
    • 0035865328 scopus 로고    scopus 로고
    • Cutting edge: peripheral neuropeptides attract immature and arrest mature blood-derived dendritic cells
    • Dunzendorfer S, Kaser A, Meierhofer C, Tilg H, Wiedermann CJ. Cutting edge: peripheral neuropeptides attract immature and arrest mature blood-derived dendritic cells. J Immunol 2001; 166:2167-72.
    • (2001) J Immunol , vol.166 , pp. 2167-2172
    • Dunzendorfer, S.1    Kaser, A.2    Meierhofer, C.3    Tilg, H.4    Wiedermann, C.J.5
  • 27
    • 0034176854 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor
    • Carucci JA, Ignatius R, Wei Yet al. Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor. J Immunol 2000; 164:3494-9.
    • (2000) J Immunol , vol.164 , pp. 3494-3499
    • Carucci, J.A.1    Ignatius, R.2    Wei, Y.3
  • 28
    • 0031015965 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide inhibits proliferation and antigen presentation by human peripheral blood mononuclear cells: effects on B7, interleukin 10, and interleukin 12
    • Fox FE, Kubin M, Cassin Met al. Calcitonin gene-related peptide inhibits proliferation and antigen presentation by human peripheral blood mononuclear cells: effects on B7, interleukin 10, and interleukin 12. J Invest Dermatol 1997; 108:43-8.
    • (1997) J Invest Dermatol , vol.108 , pp. 43-48
    • Fox, F.E.1    Kubin, M.2    Cassin, M.3
  • 29
    • 58749108125 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide biases Langerhans cells toward Th2-type immunity
    • Ding W, Stohl LL, Wagner JA, Granstein RD. Calcitonin gene-related peptide biases Langerhans cells toward Th2-type immunity. J Immunol 2008; 181:6020-6.
    • (2008) J Immunol , vol.181 , pp. 6020-6026
    • Ding, W.1    Stohl, L.L.2    Wagner, J.A.3    Granstein, R.D.4
  • 30
    • 79959559269 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide is an important regulator of cutaneous immunity: effect on Dendritic cell and T cell functions
    • Mikami N, Matsushita H, Kato Tet al. Calcitonin gene-related peptide is an important regulator of cutaneous immunity: effect on Dendritic cell and T cell functions. J Immunol 2011; 186:6886-93.
    • (2011) J Immunol , vol.186 , pp. 6886-6893
    • Mikami, N.1    Matsushita, H.2    Kato, T.3
  • 31
    • 34250853401 scopus 로고    scopus 로고
    • Negative regulation of TLR responses by the neuropeptide CGRP is mediated by the transcriptional repressor ICER
    • Harzenetter MD, Novotny AR, Gais P, Molina CA, Altmayr F, Holzmann B. Negative regulation of TLR responses by the neuropeptide CGRP is mediated by the transcriptional repressor ICER. J Immunol 2007; 179:607-15.
    • (2007) J Immunol , vol.179 , pp. 607-615
    • Harzenetter, M.D.1    Novotny, A.R.2    Gais, P.3    Molina, C.A.4    Altmayr, F.5    Holzmann, B.6
  • 32
    • 77950504628 scopus 로고    scopus 로고
    • The neuropeptide calcitonin gene-related peptide causes repression of tumor necrosis factor-alpha transcription and suppression of ATF-2 promoter recruitment in Toll-like receptor-stimulated dendritic cells
    • Altmayr F, Jusek G, Holzmann B. The neuropeptide calcitonin gene-related peptide causes repression of tumor necrosis factor-alpha transcription and suppression of ATF-2 promoter recruitment in Toll-like receptor-stimulated dendritic cells. J Biol Chem 2010; 285:3525-31.
    • (2010) J Biol Chem , vol.285 , pp. 3525-3531
    • Altmayr, F.1    Jusek, G.2    Holzmann, B.3
  • 33
    • 0037111588 scopus 로고    scopus 로고
    • Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31(hi)Ly-6C(neg) bone marrow precursors in a mouse model of asthma
    • van Rijt LS, Prins JB, Leenen PJet al. Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31(hi)Ly-6C(neg) bone marrow precursors in a mouse model of asthma. Blood 2002; 100:3663-71.
    • (2002) Blood , vol.100 , pp. 3663-3671
    • van Rijt, L.S.1    Prins, J.B.2    Leenen, P.J.3
  • 34
    • 0033968962 scopus 로고    scopus 로고
    • Sensitization to inhaled antigen by intratracheal instillation of dendritic cells
    • Lambrecht BN, Peleman RA, Bullock GR, Pauwels RA. Sensitization to inhaled antigen by intratracheal instillation of dendritic cells. Clin Exp Allergy 2000; 30:214-24.
    • (2000) Clin Exp Allergy , vol.30 , pp. 214-224
    • Lambrecht, B.N.1    Peleman, R.A.2    Bullock, G.R.3    Pauwels, R.A.4
  • 35
    • 58149214015 scopus 로고    scopus 로고
    • Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells
    • Kuipers H, Soullie T, Hammad Het al. Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells. J Leukoc Biol 2009; 85:64-70.
    • (2009) J Leukoc Biol , vol.85 , pp. 64-70
    • Kuipers, H.1    Soullie, T.2    Hammad, H.3
  • 36
    • 12244290339 scopus 로고    scopus 로고
    • Desensitisation of adrenomedullin and CGRP receptors
    • Hay DL, Poyner DR, Smith DM. Desensitisation of adrenomedullin and CGRP receptors. Regul Pept 2003; 112:139-45.
    • (2003) Regul Pept , vol.112 , pp. 139-145
    • Hay, D.L.1    Poyner, D.R.2    Smith, D.M.3
  • 37
    • 0035834719 scopus 로고    scopus 로고
    • Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin
    • Hilairet S, Belanger C, Bertrand J, Laperriere A, Foord SM, Bouvier M. Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin. J Biol Chem 2001; 276:42182-90.
    • (2001) J Biol Chem , vol.276 , pp. 42182-42190
    • Hilairet, S.1    Belanger, C.2    Bertrand, J.3    Laperriere, A.4    Foord, S.M.5    Bouvier, M.6
  • 38
    • 78649869203 scopus 로고    scopus 로고
    • Expression of functional receptor activity modifying protein 1 by airway epithelial cells with dysregulation in asthma
    • Bonner K, Kariyawasam HH, Ali FRet al. Expression of functional receptor activity modifying protein 1 by airway epithelial cells with dysregulation in asthma. J Allergy Clin Immunol 2010; 126:1277-83.
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 1277-1283
    • Bonner, K.1    Kariyawasam, H.H.2    Ali, F.R.3
  • 40
    • 3442892041 scopus 로고    scopus 로고
    • Essential role of dendritic cell CD80/CD86 costimulation in the induction, but not reactivation, of TH2 effector responses in a mouse model of asthma
    • van Rijt LS, Vos N, Willart Met al. Essential role of dendritic cell CD80/CD86 costimulation in the induction, but not reactivation, of TH2 effector responses in a mouse model of asthma. J Allergy Clin Immunol 2004; 114:166-73.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 166-173
    • van Rijt, L.S.1    Vos, N.2    Willart, M.3
  • 41
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy
    • Kuchroo VK, Das MP, Brown JAet al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995; 80:707-18.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3
  • 42
    • 0032914146 scopus 로고    scopus 로고
    • Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice
    • Haczku A, Takeda K, Redai Iet al. Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice. Am J Respir Crit Care Med 1999; 159:1638-43.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1638-1643
    • Haczku, A.1    Takeda, K.2    Redai, I.3
  • 43
    • 40949097683 scopus 로고    scopus 로고
    • Regulatory conversation between antigen presenting cells and regulatory T cells enhance immune suppression
    • Mahnke K, Bedke T, Enk AH. Regulatory conversation between antigen presenting cells and regulatory T cells enhance immune suppression. Cell Immunol 2007; 250:1-13.
    • (2007) Cell Immunol , vol.250 , pp. 1-13
    • Mahnke, K.1    Bedke, T.2    Enk, A.H.3
  • 44
    • 77954932467 scopus 로고    scopus 로고
    • Programming dendritic cells to induce Th2 and tolerogenic responses
    • Pulendran B, Tang H, Manicassamy S. Programming dendritic cells to induce Th2 and tolerogenic responses. Nat Immunol 2010; 11:647-55.
    • (2010) Nat Immunol , vol.11 , pp. 647-655
    • Pulendran, B.1    Tang, H.2    Manicassamy, S.3
  • 45
    • 1542724420 scopus 로고    scopus 로고
    • CD4+CD25+ T cells regulate airway eosinophilic inflammation by modulating the Th2 cell phenotype
    • Jaffar Z, Sivakuru T, Roberts K.CD4+CD25+ T cells regulate airway eosinophilic inflammation by modulating the Th2 cell phenotype. J Immunol 2004; 172:3842-9.
    • (2004) J Immunol , vol.172 , pp. 3842-3849
    • Jaffar, Z.1    Sivakuru, T.2    Roberts, K.3
  • 46
    • 14644414825 scopus 로고    scopus 로고
    • New insights into the molecular mechanisms of interleukin-10-mediated immunosuppression
    • Grütz G. New insights into the molecular mechanisms of interleukin-10-mediated immunosuppression. J Leukoc Biol 2005; 77:3-15.
    • (2005) J Leukoc Biol , vol.77 , pp. 3-15
    • Grütz, G.1
  • 47
    • 0036918640 scopus 로고    scopus 로고
    • Interleukin-10 is crucial for maintenance but not for developmental induction of peripheral T cell tolerance
    • Seewaldt S, Alferink J, Förster I. Interleukin-10 is crucial for maintenance but not for developmental induction of peripheral T cell tolerance. Eur J Immunol 2002; 32:3607-16.
    • (2002) Eur J Immunol , vol.32 , pp. 3607-3616
    • Seewaldt, S.1    Alferink, J.2    Förster, I.3
  • 49
    • 0037090416 scopus 로고    scopus 로고
    • Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice
    • Dakhama A, Kanehiro A, Mäkelä MJet al. Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice. Am J Respir Crit Care Med 2002; 165:1137-44.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1137-1144
    • Dakhama, A.1    Kanehiro, A.2    Mäkelä, M.J.3
  • 50
    • 0037121946 scopus 로고    scopus 로고
    • Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
    • Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 2002; 196:1645-51.
    • (2002) J Exp Med , vol.196 , pp. 1645-1651
    • Eisenbarth, S.C.1    Piggott, D.A.2    Huleatt, J.W.3    Visintin, I.4    Herrick, C.A.5    Bottomly, K.6
  • 51
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Inaba K, Dorsett Yet al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001; 194:769-79.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3
  • 52
    • 0037351927 scopus 로고    scopus 로고
    • Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors
    • Fan J, Malik AB. Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nat Med 2003; 9:315-21.
    • (2003) Nat Med , vol.9 , pp. 315-321
    • Fan, J.1    Malik, A.B.2
  • 53
    • 44449126768 scopus 로고    scopus 로고
    • Roflumilast: an oral, once-daily selective PDE-4 inhibitor for the management of COPD and asthma
    • Field SK. Roflumilast: an oral, once-daily selective PDE-4 inhibitor for the management of COPD and asthma. Expert Opin Investig Drugs 2008; 17:811-8.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 811-818
    • Field, S.K.1
  • 54
    • 38349175693 scopus 로고    scopus 로고
    • Correlation between immune and neuronal parameters and stress perception in allergic asthmatics
    • Joachim RA, Noga O, Sagach Vet al. Correlation between immune and neuronal parameters and stress perception in allergic asthmatics. Clin Exp Allergy 2008; 38:283-90.
    • (2008) Clin Exp Allergy , vol.38 , pp. 283-290
    • Joachim, R.A.1    Noga, O.2    Sagach, V.3
  • 55
    • 67649213033 scopus 로고    scopus 로고
    • Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production
    • Bailey MT, Kierstein S, Sharma Set al. Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production. J Immunol 2009; 182:7888-96.
    • (2009) J Immunol , vol.182 , pp. 7888-7896
    • Bailey, M.T.1    Kierstein, S.2    Sharma, S.3
  • 56
    • 67651108817 scopus 로고    scopus 로고
    • Stress and airway reactivity in a murine model of allergic airway inflammation
    • Quarcoo D, Pavlovic S, Joachim RA. Stress and airway reactivity in a murine model of allergic airway inflammation. Neuroimmunomodulation 2009; 16:318-24.
    • (2009) Neuroimmunomodulation , vol.16 , pp. 318-324
    • Quarcoo, D.1    Pavlovic, S.2    Joachim, R.A.3
  • 57
    • 37249055913 scopus 로고    scopus 로고
    • Pulmonary peptidergic innervation remodeling and development of airway hyperresponsiveness induced by RSV persistent infection
    • Tan YR, Yang T, Liu SPet al. Pulmonary peptidergic innervation remodeling and development of airway hyperresponsiveness induced by RSV persistent infection. Peptides 2008; 29:47-56.
    • (2008) Peptides , vol.29 , pp. 47-56
    • Tan, Y.R.1    Yang, T.2    Liu, S.P.3
  • 58
    • 53549095955 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms in the viral exacerbation of asthma
    • Tauro S, Su YC, Thomas Set al. Molecular and cellular mechanisms in the viral exacerbation of asthma. Microbes Infect 2008; 10:1014-23.
    • (2008) Microbes Infect , vol.10 , pp. 1014-1023
    • Tauro, S.1    Su, Y.C.2    Thomas, S.3
  • 59
    • 0033012030 scopus 로고    scopus 로고
    • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
    • Lutz MB, Kukutsch N, Ogilvie ALet al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 1999; 223:77-92.
    • (1999) J Immunol Methods , vol.223 , pp. 77-92
    • Lutz, M.B.1    Kukutsch, N.2    Ogilvie, A.L.3
  • 60
    • 72049121657 scopus 로고    scopus 로고
    • A Toll-like receptor 2/6 agonist reduces allergic airway inflammation in chronic respiratory sensitisation to Timothy grass pollen antigens
    • Fuchs B, Knothe S, Rochlitzer Set al. A Toll-like receptor 2/6 agonist reduces allergic airway inflammation in chronic respiratory sensitisation to Timothy grass pollen antigens. Int Arch Allergy Immunol 2010; 152:131-9.
    • (2010) Int Arch Allergy Immunol , vol.152 , pp. 131-139
    • Fuchs, B.1    Knothe, S.2    Rochlitzer, S.3


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