Host factors in enterovirus 71 replication

Journal of Virology

Volumn 85, Issue 19, 2011, Pages 9658-9666

  Shih, Shin Ru ^a   Stollar, Victor ^b,c   Li, Mei Ling ^a,b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE STIMULATION FACTOR 64; FAR UPSTREAM ELEMENT BINDING PROTEIN 1; FAR UPSTREAM ELEMENT BINDING PROTEIN 2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; HOST FACTOR; INITIATION FACTOR; IRES SPECIFIC TRANS ACTING FACTOR; MESSENGER RNA; MESSENGER RNA PRECURSOR; NUCLEAR PROTEIN; RETICULON 3; TRANS ACTING FACTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

CYTOPLASM; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; ENZYME ACTIVITY; HUMAN; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RNA CLEAVAGE; RNA PROCESSING; RNA SYNTHESIS; SHORT SURVEY; TRANSLATION INITIATION; VIRUS CELL INTERACTION; VIRUS REPLICATION;

ENTEROVIRUS A, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; RNA, VIRAL; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN ENTEROVIRUS 71;

EID: 80053992186     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05063-11     Document Type: Short Survey

References (105)

1. AbuBakar, S., et al. 2009. Enterovirus 71 outbreak, Brunei. Emerg. Infect. Dis. 15:79-82.
2. Alexander, J. P., Jr., L. Baden, M. A. Pallansch, and L. J. Anderson. 1994. Enterovirus 71 infections and neurologic disease-United States, 1977-1991. J. Infect. Dis. 169:905-908.
3. Andreev, D. E., et al. 2007. Differential factor requirement to assemble translation initiation complexes at the alternative start codons of foot-andmouth disease virus RNA. RNA 13:1366-1374.
4. Argos, P., G. Kamer, M. J. Nicklin, and E. Wimmer. 1984. Similarity in gene organization and homology between proteins of animal picornaviruses and a plant comovirus suggest common ancestry of these virus families. Nucleic Acids Res. 12:7251-7267.
5. Bedard, K. M., and B. L. Semler. 2004. Regulation of picornavirus gene expression. Microbes Infect. 6:702-713.
6. Belsham, G. J. 2009. Divergent picornavirus IRES elements. Virus Res. 139:183-192.
7. Borman, A. M., J. L. Bailly, M. Girard, and K. M. Kean. 1995. Picornavirus internal ribosome entry segments: comparison of translation efficiency and the requirements for optimal internal initiation of translation in vitro. Nucleic Acids Res. 23:3656-3663.
8. Borman, A. M., Y. M. Michel, and K. M. Kean. 2001. Detailed analysis of the requirements of hepatitis A virus internal ribosome entry segment for the eukaryotic initiation factor complex eIF4F. J. Virol. 75:7864-7871.
9. Brown, B. A., M. S. Oberste, J. P. Alexander, Jr., M. L. Kennett, and M. A. Pallansch. 1999. Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998. J. Virol. 73:9969-9975.
10. Bryant, H. E., et al. 2000. Interaction between herpes simplex virus type 1 IE63 protein and cellular protein p32. J. Virol. 74:11322-11328.
11. Burnham, A. J., L. Gong, and R. W. Hardy. 2007. Heterogeneous nuclear ribonuclear protein K interacts with Sindbis virus nonstructural proteins and viral subgenomic mRNA. Virology 367:212-221.
12. Cammas, A., et al. 2007. Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs. Mol. Biol. Cell 18:5048-5059.
13. Cartegni, L., S. L. Chew, and A. R. Krainer. 2002. Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat. Rev. Genet. 3:285-298.
14. Chang, C. J., et al. 2001. The heterogeneous nuclear ribonucleoprotein K (hnRNP K) interacts with dengue virus core protein. DNA Cell Biol. 20:569-577.
15. Chen, M., and J. L. Manley. 2009. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat. Rev. Mol. Cell Biol. 10:741-754.
16. Chen, R., et al. 2011. Reticulon 3 attenuates the clearance of cytosolic prion aggregates via inhibiting autophagy. Autophagy 7:205-216.
17. Cheunim, T., J. Zhang, S. G. Milligan, M. G. McPhillips, and S. V. Graham. 2008. The alternative splicing factor hnRNP A1 is up-regulated during virus-infected epithelial cell differentiation and binds the human papillomavirus type 16 late regulatory element. Virus Res. 131:189-198.
18. Chien, H. L., C. L. Liao, and Y. L. Lin. 2011. The FUSE binding protein 1 interacts with untranslated regions of Japanese encephalitis virus RNA and negatively regulates viral replication. J. Virol. 85:4698-4706.
19. Chook, Y. M., and G. Blobel. 1999. Structure of the nuclear transport complex karyopherin-β2-Ran GppNHp. Nature 399:230-237.
20. Colgan, D. F., and J. L. Manley. 1997. Mechanism and regulation of mRNA polyadenylation. Genes Dev. 11:2755-2766.
21. Davis-Smyth, T., R. C. Duncan, T. Zheng, G. Michelotti, and D. Levens. 1996. The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators. J. Biol. Chem. 271:31679-31687.
22. de Breyne, S., Y. Yu, A. Unbehaun, T. V. Pestova, and C. U. Hellen. 2009. Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites. Proc. Natl. Acad. Sci. U. S. A. 106:9197-9202.
23. De Jesus, N. H. 2007. Epidemics to eradication: the modern history of poliomyelitis. Virol. J. 4:70.
24. Dobbyn, H. C., et al. 2008. Regulation of BAG-1 IRES-mediated translation following chemotoxic stress. Oncogene 27:1167-1174.
25. Dreyfuss, G., M. J. Matunis, S. Pinol-Roma, and C. G. Burd. 1993. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62:289-321.
26. Duncan, R., et al. 1994. A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNAbinding motif. Genes Dev. 8:465-480.
27. Engidawork, E., L. Afjehi-Sadat, J. W. Yang, I. Slavc, and G. Lubec. 2006. Protein chemical identification and characterization of the human variants of far upstream element binding protein in medulloblastoma DAOY cell line. Int. J. Oncol. 29:721-736.
28. Fitzgerald, K. D., and B. L. Semler. 2009. Bridging IRES elements in mRNAs to the eukaryotic translation apparatus. Biochim. Biophys. Acta 1789:518-528.
29. Gamarnik, A. V., and R. Andino. 1998. Switch from translation to RNA replication in a positive-stranded RNA virus. Genes Dev. 12:2293-2304.
30. Grossman, J. S., et al. 1998. The use of antibodies to the polypyrimidine tract binding protein (PTB) to analyze the protein components that assemble on alternatively spliced pre-mRNAs that use distant branch points. RNA 4:613-625.
31. Gui, H., C. W. Lu, S. Adams, V. Stollar, and M. L. Li. 2010. hnRNP A1 interacts with the genomic and subgenomic RNA promoters of Sindbis virus and is required for the synthesis of G and SG RNA. J. Biomed. Sci. 17:59.
32. He, L., A. Weber, and D. Levens. 2000. Nuclear targeting determinants of the far upstream element binding protein, a c-myc transcription factor. Nucleic Acids Res. 28:4558-4565.
33. Hellen, C. U. 2009. IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry. Biochim. Biophys. Acta 1789:558-570.
34. Ho, M., et al. 1999. An epidemic of enterovirus 71 infection in Taiwan. N. Engl. J. Med. 341:929-935.
35. Hsieh, T. Y., et al. 1998. Hepatitis C virus core protein interacts with heterogeneous nuclear ribonucleoprotein K. J. Biol. Chem. 273:17651-17659.
36. Reference deleted
37. Irwin, N., V. Baekelandt, L. Goritchenko, and L. I. Benowitz. 1997. Identification of two proteins that bind to a pyrimidine-rich sequence in the 3'-untranslated region of GAP-43 mRNA. Nucleic Acid Res. 25:1281-1288.
38. Jang, S. K., et al. 1988. A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J. Virol. 62:2636-2643.
39. Joachims, M., P. C. Van Breugel, and R. E. Lloyd. 1999. Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro. J. Virol. 73:718-727.
40. Kehle, J., B. Roth, C. Metzger, A. Pfitzner, and G. Enders. 2003. Molecular characterization of an enterovirus 71 causing neurological disease in Germany. J. Neurovirol. 9:126-128.
41. Kim, C. S., S. K. Seol, O. K. Song, J. H. Park, and S. K. Jang. 2007. An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replication. J. Virol. 81:3852-3865.
42. Kolupaeva, V. G., S. de Breyne, T. V. Pestova, and C. U. Hellen. 2007. In vitro reconstitution and biochemical characterization of translation initiation by internal ribosomal entry. Methods Enzymol. 430:409-439.
43. Koroleva, G. A., L. A. Gracheva, and M. K. Voroshilova. 1978. Isolation of type 71 enterovirus from patients with a poliomyelitis-like disease during an outbreak in Bulgaria. Vopr. Virusol. 5:611-618. (In Russian.)
44. Krausslich, H. G., M. J. Nicklin, H. Toyoda, D. Etchison, and E. Wimmer. 1987. Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. J. Virol. 61:2711-2718.
45. Lee, B. Y., et al. 2010. Forecasting the economic value of an enterovirus 71 (EV71) vaccine. Vaccine 28:7731-7736.
46. Lewis, S. M., and M. Holcik. 2008. For IRES trans-acting factors, it is all about location. Oncogene 27:1033-1035.
47. Lewis, S. M., et al. 2007. Subcellular relocalization of a trans-acting factor regulates XIAP IRES-dependent translation. Mol. Biol. Cell 18:1302-1311.
48. Li, M. L., et al. 2002. The 3C protease activity of enterovirus 71 induces human neural cell apoptosis. Virology 293:386-395.
49. Lin, J. C., M. Hsu, and W. Y. Tarn. 2007. Cell stress modulates the function of splicing regulatory protein RBM4 in translation control. Proc. Natl. Acad. Sci. U. S. A. 104:2235-2240.
50. Lin, J. Y., et al. 2009. Viral and host proteins involved in picornavirus life cycle. J. Biomed. Sci. 16:103.
51. Lin, J. Y., et al. 2008. Heterogeneous nuclear ribonuclear protein K interacts with the enterovirus 71 5' untranslated region and participates in virus replication. J. Gen. Virol. 89:2540-2549.
52. Lin, J. Y., M. L. Li, and S. R. Shih. 2009. Far upstream element binding protein 2 interacts with enterovirus 71 internal ribosomal entry site and negatively regulates viral translation. Nucleic Acids Res. 37:47-59.
53. Lin, J. Y., et al. 2009. hnRNP A1 interacts with the 5' untranslated regions of enterovirus 71 and Sindbis virus RNA and is required for viral replication. J. Virol. 83:6106-6114.
54. MacDonald, C. C., J. Wilusz, and T. Shenk. 1994. The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location. Mol. Cell. Biol. 14:6647-6654.
55. Martinez-Salas, E. 2008. The impact of RNA structure on picornavirus IRES activity. Trends Microbiol. 16:230-237.
56. McMinn, P. C. 2002. An overview of the evolution of enterovirus 71 and its clinical and public health significance. FEMS Microbiol. Rev. 26:91-107.
57. Melnick, J. L. 1984. Enterovirus type 71 infections: a varied clinical pattern sometimes mimicking paralytic poliomyelitis. Rev. Infect. Dis. 6(Suppl. 2):S387-S390.
58. Michlewski, G., and J. F. Caceres. 2010. Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat. Struct. Mol. Biol. 17:1011-1018.
59. Min, H., C. W. Turck, J. M. Nikolic, and D. L. Black. 1997. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev. 11:1023-1036.
60. Nagy, G., S. Takatsy, E. Kukan, I. Mihaly, and I. Domok. 1982. Virological diagnosis of enterovirus type 71 infections: experiences gained during an epidemic of acute CNS diseases in Hungary in 1978. Arch. Virol. 71:217-227.
61. Niepmann, M. 2009. Internal translation initiation of picornaviruses and hepatitis C virus. Biochim. Biophys. Acta 1789:529-541.
62. Nishimura, Y., et al. 2009. Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71. Nat. Med. 15:794-797.
63. Oertle, T., and M. E. Schwab. 2003. Nogo and its paRTNers. Trends Cell Biol. 13:187-194.
64. Ooi, M. H., S. C. Wong, P. Lewthwaite, M. J. Cardosa, and T. Solomon. 2010. Clinical features, diagnosis, and management of enterovirus 71. Lancet Neurol. 9:1097-1105.
65. Pacheco, A., and E. Martinez-Salas. 2010. Insights into the biology of IRES elements through riboproteomic approaches. J. Biomed. Biotechnol. 2010: 458927.
66. Paranjape, S. M., and E. Harris. 2007. Y box-binding protein-1 binds to the dengue virus 3'-untranslated region and mediates antiviral effects. J. Biol. Chem. 282:30497-30508.
67. Paul, A. V., A. Molla, and E. Wimmer. 1994. Studies of a putative amphipathic helix in the N-terminus of poliovirus protein 2C. Virology 199:188-199.
68. Pelletier, J., and N. Sonenberg. 1988. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334:320-325.
69. Pettit Kneller, E. L., J. H. Connor, and D. S. Lyles. 2009. hnRNPs relocalize to the cytoplasm following infection with vesicular stomatitis virus. J. Virol. 83:770-780.
70. Pilipenko, E. V., E. G. Viktorova, S. T. Guest, V. I. Agol, and R. P. Roos. 2001. Cell-specific proteins regulate viral RNA translation and virus-induced disease. EMBO J. 20:6899-6908.
71. Racaniello, V. R. 2007. Picornaviridae: the viruses and their replication, p. 796-838. In D. M. Knipe et al. (ed.), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
72. Samuda, G. M., W. K. Chang, C. Y. Yeung, and P. S. Tang. 1987. Monoplegia caused by enterovirus 71: an outbreak in Hong Kong. Pediatr. Infect. Dis. J. 6:206-208.
73. Sanz, M. A., E. Welnowska, N. Redondo, and L. Carrasco. 2010. Translation driven by picornavirus IRES is hampered from Sindbis virus replicons: rescue by poliovirus 2A protease. J. Mol. Biol. 402:101-117.
74. Schmidt, N. J., E. H. Lennette, and H. H. Ho. 1974. An apparently new enterovirus isolated from patients with disease of the central nervous system. J. Infect. Dis. 129:304-309.
75. Shi, S. T., P. Huang, H. P. Li, and M. M. Lai. 2000. Heterogeneous nuclear ribonucleoprotein A1 regulates RNA synthesis of a cytoplasmic virus. EMBO J. 19:4701-4711.
76. Shih, S. R., et al. 2004. Identification of genes involved in the host response to enterovirus 71 infection. J. Neurovirol. 10:293-304.
77. Shimada, K., K. Kondo, and K. Yamanishi. 2004. Human herpesvirus 6 immediate-early 2 protein interacts with heterogeneous ribonucleoprotein K and casein kinase 2. Microbiol. Immunol. 48:205-210.
78. Shimizu, H., et al. 1999. Enterovirus 71 from fatal and nonfatal cases of hand, foot and mouth disease epidemics in Malaysia, Japan and Taiwan in 1997-1998. Jpn. J. Infect. Dis. 52:12-15.
79. Shindarov, L. M., et al. 1979. Epidemiological, clinical, and pathomorphological characteristics of epidemic poliomyelitis-like disease caused by enterovirus J. Hyg. Epidemiol. Microbiol. Immunol. 23:284-295.
80. Silvestri, L. S., J. M. Parilla, B. J. Morasco, S. A. Ogram, and J. B. Flanegan. 2006. Relationship between poliovirus negative-strand RNA synthesis and the length of the 3' poly(A) tail. Virology 345:509-519.
81. Siomi, H., and G. Dreyfuss. 1995. A nuclear localization domain in the hnRNP A1 protein. J. Cell Biol. 129:551-560.
82. Siomi, H., M. J. Matunis, W. M. Michael, and G. Dreyfuss. 1993. The pre-mRNA binding K protein contains a novel evolutionarily conserved motif. Nucleic Acids Res. 21:1193-1198.
83. Solomon, T., et al. 2010. Virology, epidemiology, pathogenesis, and control of enterovirus 71. Lancet Infect. Dis. 10:778-790.
84. Tang, W. F., et al. 2007. Reticulon 3 binds the 2C protein of enterovirus 71 and is required for viral replication. J. Biol. Chem. 282:5888-5898.
85. Thompson, S. R., and P. Sarnow. 2003. Enterovirus 71 contains a type I IRES element that functions when eukaryotic initiation factor eIF4G is cleaved. Virology 315:259-266.
86. Ting, N. S., B. Pohorelic, Y. Yu, S. P. Lees-Miller, and T. L. Beattie. 2009. The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1. Nucleic Acids Res. 37:6105-6115.
87. Tomonaga, T., and D. Levens. 1995. Heterogeneous nuclear ribonucleoprotein K is a DNA-binding transactivator. J. Biol. Chem. 270:4875-4881.
88. Vindigni, A., A. Ochem, G. Triolo, and A. Falaschi. 2001. Identification of human DNA helicase V with the far upstream element-binding protein. Nucleic Acids Res. 29:1061-1067.
89. Vogt, D. A., and R. Andino. 2010. An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis. PLoS Pathog. 6:e1000936.
90. Wang, Y. F., S. C. Chen, F. Y. Wu, and C. W. Wu. 1997. The interaction between human cytomegalovirus immediate-early gene 2 (IE2) protein and heterogeneous ribonucleoprotein A1. Biochem. Biophys. Res. Commun. 232:590-594.
91. Weighardt, F., G. Biamonti, and S. Riva. 1995. Nucleo-cytoplasmic distribution of human hnRNP proteins: a search for the targeting domains in hnRNP A1. J. Cell Sci. 108:545-555.
92. Weighardt, F., G. Biamonti, and S. Riva. 1996. The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism. Bioessays 18: 747-756.
93. Weng, K. F., L. L. Chen, P. N. Huang, and S. R. Shih. 2010. Neural pathogenesis of enterovirus 71 infection. Microbes. Infect. 12:505-510.
94. Weng, K. F., M. L. Li, C. T. Hung, and S. R. Shih. 2009. Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation. PLoS Pathog. 5:e1000593.
95. Wimmer, E., and A. Nomoto. 1993. Molecular biology and cell-free synthesis of poliovirus. Biologicals 21:349-356.
96. Wu, K. X., M. M. Ng, and J. J. Chu. 2010. Developments towards antiviral therapies against enterovirus 71. Drug Discov. Today 15:1041-1051.
97. Yamayoshi, S., et al. 2009. Scavenger receptor B2 is a cellular receptor for enterovirus 71. Nat. Med. 15:798-801.
98. Yang, F., et al. 2009. Enterovirus 71 outbreak in the People's Republic of China in 2008. J. Clin. Microbiol. 47:2351-2352.
99. Yang, Y. S., and S. M. Strittmatter. 2007. The reticulons: a family of proteins with diverse functions. Genome Biol. 8:234.
100. Yu, Y., I. S. Abaeva, A. Marintchev, T. V. Pestova, and C. U. Hellen. 2011. Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors. Nucleic Acids Res. 39:4851-4865.
101. Zhang, W., et al. 2008. Cytidine deaminase APOBEC3B interacts with heterogeneous nuclear ribonucleoprotein K and suppresses hepatitis B virus expression. Cell Microbiol. 10:112-121.
102. Zhang, Z., D. Harris, and V. N. Pandey. 2008. The FUSE binding protein is a cellular factor required for efficient replication of hepatitis C virus. J. Virol. 82:5761-5773.
103. Zhao, X., M. Rush, and S. Schwartz. 2004. Identification of an hnRNP A1-dependent splicing silencer in the human papillomavirus type 16 L1 coding region that prevents premature expression of the late L1 gene. J. Virol. 78:10888-10905.
104. Zoll, J., H. A. Heus, F. J. van Kuppeveld, and W. J. Melchers. 2009. The structure-function relationship of the enterovirus 3-UTR. Virus Res. 139: 209-216.
105. Zou, H., W. J. Henzel, X. Liu, A. Lutschg, and X. Wang. 1997. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-413.