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Volumn 7, Issue 2, 2011, Pages 205-216

Reticulon 3 attenuates the clearance of cytosolic prion aggregates by inhibiting autophagy

Author keywords

Apoptosis; Autophagy; Er stress; Prion; RTN3; UPS

Indexed keywords

BECLIN 1; PRION PROTEIN; PROTEIN; PROTEIN BCL 2; RETICULON 3; UNCLASSIFIED DRUG;

EID: 79551568451     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.7.2.14197     Document Type: Article
Times cited : (34)

References (43)
  • 2
    • 4644357534 scopus 로고    scopus 로고
    • Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation
    • DOI 10.1038/nm1088
    • He W, Lu Y, Qahwash I, Hu XY, Chang A, Yan R. Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation. Nat Med 2004; 10:959-65. (Pubitemid 39273737)
    • (2004) Nature Medicine , vol.10 , Issue.9 , pp. 959-965
    • He, W.1    Lu, Y.2    Qahwash, I.3    Hu, X.-Y.4    Chang, A.5    Yan, R.6
  • 3
    • 35748960521 scopus 로고    scopus 로고
    • The membrane topology of RTN3 and its effect on binding of RTN3 to BACE1
    • He W, Shi Q, Hu X, Yan R. The membrane topology of RTN3 and its effect on binding of RTN3 to BACE1. J Biol Chem 2007; 282:29144-51.
    • (2007) J Biol Chem , vol.282 , pp. 29144-29151
    • He, W.1    Shi, Q.2    Hu, X.3    Yan, R.4
  • 4
    • 34250019939 scopus 로고    scopus 로고
    • Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities
    • Hu X, Shi Q, Zhou X, He W, Yi H, Yin X, et al. Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. EMBO J 2007; 26:2755-67.
    • (2007) EMBO J , vol.26 , pp. 2755-2767
    • Hu, X.1    Shi, Q.2    Zhou, X.3    He, W.4    Yi, H.5    Yin, X.6
  • 6
    • 21644448744 scopus 로고    scopus 로고
    • 2+ depletion triggers apoptotic signals for endoplasmic reticulum (ER) overload response induced by overexpressed reticulon 3 (RTN3/HAP)
    • DOI 10.1002/jcp.20340
    • Kuang E, Wan Q, Li X, Xu H, Liu Q, Qi Y. ER Ca2+ depletion triggers apoptotic signals for endoplasmic reticulum (ER) overload response induced by overexpressed reticulon 3 (RTN3/HAP). J Cell Physiol 2005; 204:549-59. (Pubitemid 40934650)
    • (2005) Journal of Cellular Physiology , vol.204 , Issue.2 , pp. 549-559
    • Kuang, E.1    Wan, Q.2    Li, X.3    Xu, H.4    Liu, Q.5    Qi, Y.6
  • 7
    • 33846492356 scopus 로고    scopus 로고
    • Reticulon 3 mediates Bcl-2 accumulation in mitochondria in response to endoplasmic reticulum stress
    • Wan Q, Kuang E, Dong W, Zhou S, Xu H, Qi Y, Liu Y. Reticulon 3 mediates Bcl-2 accumulation in mitochondria in response to endoplasmic reticulum stress. Apoptosis 2007; 12:319-28.
    • (2007) Apoptosis , vol.12 , pp. 319-328
    • Wan, Q.1    Kuang, E.2    Dong, W.3    Zhou, S.4    Xu, H.5    Qi, Y.6    Liu, Y.7
  • 8
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122:927-39.
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 9
    • 0037264120 scopus 로고    scopus 로고
    • Unfolding the role of protein misfolding in neurodegenerative diseases
    • Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nat Rev Neurosci 2003; 4:49-60.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 49-60
    • Soto, C.1
  • 11
    • 2642586352 scopus 로고    scopus 로고
    • Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
    • Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, Oroz LG, et al. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet 2004; 36:585-95.
    • (2004) Nat Genet , vol.36 , pp. 585-595
    • Ravikumar, B.1    Vacher, C.2    Berger, Z.3    Davies, J.E.4    Luo, S.5    Oroz, L.G.6
  • 12
    • 26444587508 scopus 로고    scopus 로고
    • Macroautophagy - A novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
    • Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, et al. Macroautophagy - a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. J Cell Biol 2005; 171:87-98.
    • (2005) J Cell Biol , vol.171 , pp. 87-98
    • Yu, W.H.1    Cuervo, A.M.2    Kumar, A.3    Peterhoff, C.M.4    Schmidt, S.D.5    Lee, J.H.6
  • 14
    • 4344656905 scopus 로고    scopus 로고
    • Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: A brain biopsy study
    • DOI 10.1016/j.biocel.2004.04.014, PII S1357272504001682
    • Sikorska B, Liberski PP, Giraud P, Kopp N, Brown P. Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: a brain biopsy study. Int J Biochem Cell Biol 2004; 36:2563-73. (Pubitemid 39119767)
    • (2004) International Journal of Biochemistry and Cell Biology , vol.36 , Issue.12 , pp. 2563-2573
    • Sikorska, B.1    Liberski, P.P.2    Giraud, P.3    Kopp, N.4    Brown, P.5
  • 15
    • 0142105406 scopus 로고    scopus 로고
    • Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein
    • Hetz C, Russelakis-Carneiro M, Maundrell K, Castilla J, Soto C. Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. EMBO J 2003; 22:5435-45.
    • (2003) EMBO J , vol.22 , pp. 5435-5445
    • Hetz, C.1    Russelakis-Carneiro, M.2    Maundrell, K.3    Castilla, J.4    Soto, C.5
  • 16
    • 33845459165 scopus 로고    scopus 로고
    • Autophagy is activated for cell survival after endoplasmic reticulum stress
    • Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S, et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 2006; 26:9220-31.
    • (2006) Mol Cell Biol , vol.26 , pp. 9220-9231
    • Ogata, M.1    Hino, S.2    Saito, A.3    Morikawa, K.4    Kondo, S.5    Kanemoto, S.6
  • 17
    • 0037195647 scopus 로고    scopus 로고
    • Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol
    • Ma J, Wollmann R, Lindquist S. Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol. Science 2002; 298:1781-5.
    • (2002) Science , vol.298 , pp. 1781-1785
    • Ma, J.1    Wollmann, R.2    Lindquist, S.3
  • 21
    • 34250351315 scopus 로고    scopus 로고
    • Perturbation of endoplasmic reticulum homeostasis facilitates prion replication
    • Hetz C, Castilla J, Soto C. Perturbation of endoplasmic reticulum homeostasis facilitates prion replication. J Biol Chem 2007; 282:12725-33.
    • (2007) J Biol Chem , vol.282 , pp. 12725-12733
    • Hetz, C.1    Castilla, J.2    Soto, C.3
  • 23
    • 61849102412 scopus 로고    scopus 로고
    • Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy
    • Heiseke A, Aguib Y, Riemer C, Baier M, Schatzl HM. Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy. J Neurochem 2009; 109:25-34.
    • (2009) J Neurochem , vol.109 , pp. 25-34
    • Heiseke, A.1    Aguib, Y.2    Riemer, C.3    Baier, M.4    Schatzl, H.M.5
  • 24
    • 4744361580 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells
    • Ertmer A, Gilch S, Yun SW, Flechsig E, Klebl B, Stein- Gerlach M, et al. The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells. J Biol Chem 2004; 279:41918-27.
    • (2004) J Biol Chem , vol.279 , pp. 41918-41927
    • Ertmer, A.1    Gilch, S.2    Yun, S.W.3    Flechsig, E.4    Klebl, B.5    Stein-Gerlach, M.6
  • 25
    • 0036566266 scopus 로고    scopus 로고
    • Aggregateprone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
    • Ravikumar B, Duden R, Rubinsztein DC. Aggregateprone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum Mol Genet 2002; 11:1107-17.
    • (2002) Hum Mol Genet , vol.11 , pp. 1107-1117
    • Ravikumar, B.1    Duden, R.2    Rubinsztein, D.C.3
  • 26
    • 4344659685 scopus 로고    scopus 로고
    • Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
    • DOI 10.1126/science.1101738
    • Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D. Impaired degradation of mutant alphasynuclein by chaperone-mediated autophagy. Science 2004; 305:1292-5. (Pubitemid 39129234)
    • (2004) Science , vol.305 , Issue.5688 , pp. 1292-1295
    • Cuervo, A.M.1    Stafanis, L.2    Fredenburg, R.3    Lansbury, P.T.4    Sulzer, D.5
  • 27
    • 34250183177 scopus 로고    scopus 로고
    • HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
    • Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, et al. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007; 447:859-63.
    • (2007) Nature , vol.447 , pp. 859-863
    • Pandey, U.B.1    Nie, Z.2    Batlevi, Y.3    McCray, B.A.4    Ritson, G.P.5    Nedelsky, N.B.6
  • 28
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 29
    • 66449099090 scopus 로고    scopus 로고
    • Autophagy suppresses tumorigenesis through elimination of p62
    • Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 2009; 137:1062-75.
    • (2009) Cell , vol.137 , pp. 1062-1075
    • Mathew, R.1    Karp, C.M.2    Beaudoin, B.3    Vuong, N.4    Chen, G.5    Chen, H.Y.6
  • 30
    • 5444264022 scopus 로고    scopus 로고
    • Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
    • Lu PD, Harding HP, Ron D. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. J Cell Biol 2004; 167:27-33.
    • (2004) J Cell Biol , vol.167 , pp. 27-33
    • Lu, P.D.1    Harding, H.P.2    Ron, D.3
  • 32
    • 33750363298 scopus 로고    scopus 로고
    • The roles of intracellular proteindegradation pathways in neurodegeneration
    • Rubinsztein DC. The roles of intracellular proteindegradation pathways in neurodegeneration. Nature 2006; 443:780-6.
    • (2006) Nature , vol.443 , pp. 780-786
    • Rubinsztein, D.C.1
  • 33
    • 49049096562 scopus 로고    scopus 로고
    • Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
    • Boland B, Kumar A, Lee S, Platt FM, Wegiel J, Yu WH, Nixon RA. Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J Neurosci 2008; 28:6926-37.
    • (2008) J Neurosci , vol.28 , pp. 6926-6937
    • Boland, B.1    Kumar, A.2    Lee, S.3    Platt, F.M.4    Wegiel, J.5    Yu, W.H.6    Nixon, R.A.7
  • 34
    • 28844475400 scopus 로고    scopus 로고
    • HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
    • Iwata A, Riley BE, Johnston JA, Kopito RR. HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J Biol Chem 2005; 280:40282-92.
    • (2005) J Biol Chem , vol.280 , pp. 40282-40292
    • Iwata, A.1    Riley, B.E.2    Johnston, J.A.3    Kopito, R.R.4
  • 35
    • 70350550208 scopus 로고    scopus 로고
    • Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
    • Spencer B, Potkar R, Trejo M, Rockenstein E, Patrick C, Gindi R, et al. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J Neurosci 2009; 29:13578-88.
    • (2009) J Neurosci , vol.29 , pp. 13578-13588
    • Spencer, B.1    Potkar, R.2    Trejo, M.3    Rockenstein, E.4    Patrick, C.5    Gindi, R.6
  • 36
    • 77749319356 scopus 로고    scopus 로고
    • Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein
    • Bauer PO, Goswami A, Wong HK, Okuno M, Kurosawa M, Yamada M, et al. Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein. Nat Biotechnol 2010; 28:256-63.
    • (2010) Nat Biotechnol , vol.28 , pp. 256-263
    • Bauer, P.O.1    Goswami, A.2    Wong, H.K.3    Okuno, M.4    Kurosawa, M.5    Yamada, M.6
  • 37
    • 77950519875 scopus 로고    scopus 로고
    • Real-time visualization of prion transport in single live cells using quantum dots
    • Luo K, Li S, Xie M, Wu D, Wang W, Chen R, et al. Real-time visualization of prion transport in single live cells using quantum dots. Biochem Biophys Res Commun 2010; 394:493-7.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 493-497
    • Luo, K.1    Li, S.2    Xie, M.3    Wu, D.4    Wang, W.5    Chen, R.6
  • 38
    • 0034023407 scopus 로고    scopus 로고
    • Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells
    • Dantuma NP, Lindsten K, Glas R, Jellne M, Masucci MG. Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells. Nat Biotechnol 2000; 18:538-43.
    • (2000) Nat Biotechnol , vol.18 , pp. 538-543
    • Dantuma, N.P.1    Lindsten, K.2    Glas, R.3    Jellne, M.4    Masucci, M.G.5
  • 39
    • 0141621215 scopus 로고    scopus 로고
    • Induction of Grp78/BiP by translational block: Activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements
    • Luo S, Baumeister P, Yang S, Abcouwer SF, Lee AS. Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements. J Biol Chem 2003; 278:37375-85.
    • (2003) J Biol Chem , vol.278 , pp. 37375-37385
    • Luo, S.1    Baumeister, P.2    Yang, S.3    Abcouwer, S.F.4    Lee, A.S.5
  • 40
    • 0037023726 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP
    • Gotoh T, Oyadomari S, Mori K, Mori M. Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP. J Biol Chem 2002; 277:12343-50.
    • (2002) J Biol Chem , vol.277 , pp. 12343-12350
    • Gotoh, T.1    Oyadomari, S.2    Mori, K.3    Mori, M.4
  • 42
    • 53349168904 scopus 로고    scopus 로고
    • The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
    • Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, et al. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 2008; 29:538-50.
    • (2008) Immunity , vol.29 , pp. 538-550
    • Zhong, B.1    Yang, Y.2    Li, S.3    Wang, Y.Y.4    Li, Y.5    Diao, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.