Lung-specific loss of the laminin α3 subunit confers resistance to mechanical injury

Journal of Cell Science

Volumn 124, Issue 17, 2011, Pages 2927-2937

  Urich, Daniela ^a   Eisenberg, Jessica L ^a   Hamill, Kevin J ^a   Takawira, Desire ^a   Chiarella, Sergio E ^a   Soberanes, Saul ^a   Gonzalez, Angel ^a   Koentgen, Frank ^b   Manghi, Tomas ^a   Hopkinson, Susan B ^a   Misharin, Alexander V ^a   Perlman, Harris ^a   Mutlu, Gokhan M ^a   Budinger, G R Scott ^a   Jones, Jonathan C R ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Ozgene Pty Ltd   (Australia)

Author keywords

Basement membrane; Extracellular matrix; Laminin; Lung

Indexed keywords

ADENOVIRUS VECTOR; COLLAGEN; CRE RECOMBINASE; ETANERCEPT; LAMININ; LAMININ ALPHA3; UNCLASSIFIED DRUG;

AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BODY WEIGHT; CAPILLARY PERMEABILITY; CONTROLLED STUDY; ENZYME METABOLISM; GENE; GENETIC CODE; HISTOLOGY; INTRACELLULAR SIGNALING; KNOCKOUT MOUSE; LAMA3 GENE; LUNG ALVEOLUS EPITHELIUM; LUNG HOMOGENATE; LUNG MECHANICS; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SURVIVAL; TIDAL VOLUME; VENTILATOR INDUCED LUNG INJURY;

ADENOVIRIDAE; ANIMALS; COLLAGEN TYPE I; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; HUMANS; LAMININ; LUNG; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PNEUMONIA; POSITIVE-PRESSURE RESPIRATION; PULMONARY ALVEOLI; VENTILATOR-INDUCED LUNG INJURY;

ADENOVIRIDAE; MUS;

EID: 80053975851     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.080911     Document Type: Article

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