메뉴 건너뛰기




Volumn 223, Issue 1, 2011, Pages 57-67

Th1, Th2, Th17 and regulatory T cell pattern in psoriatic patients: Modulation of cytokines and gene targets induced by etanercept treatment and correlation with clinical response

Author keywords

Cytokines; Etanercept; Gene expression; Psoriasis; Regulatory T cells; Transcription factors

Indexed keywords

ETANERCEPT; GAMMA INTERFERON; INTERLEUKIN 12P35; INTERLEUKIN 2; INTERLEUKIN 23P19; INTERLEUKIN 4; MESSENGER RNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STAT3 PROTEIN; STAT4 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

EID: 80053965211     PISSN: 10188665     EISSN: 14219832     Source Type: Journal    
DOI: 10.1159/000330330     Document Type: Article
Times cited : (78)

References (39)
  • 2
    • 33847757147 scopus 로고    scopus 로고
    • Cracking the cytokine code in psoriasis
    • DOI 10.1038/nm0307-242, PII NM0307242
    • Nickoloff BJ: Cracking the cytokine code in psoriasis. Nat Med 2007; 13: 242-244. (Pubitemid 46376653)
    • (2007) Nature Medicine , vol.13 , Issue.3 , pp. 242-244
    • Nickoloff, B.J.1
  • 3
    • 79955622264 scopus 로고    scopus 로고
    • Contrasting pathogenesis of atopic dermatitis and psoriasis. Immune cell subsets and therapeutic concepts
    • Guttman-Yassky E, Nograles KE, Krueger JG: Contrasting pathogenesis of atopic dermatitis and psoriasis. Immune cell subsets and therapeutic concepts. J Allergy Clin Immunol 2011; 127: 1420-1432.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1420-1432
    • Guttman-Yassky, E.1    Nograles, K.E.2    Krueger, J.G.3
  • 4
    • 77955559507 scopus 로고    scopus 로고
    • Expression of Th1 and Th2 cytokine-associated transcription factors, T-bet and GATA-3, in peripheral blood mononuclear cells and skin lesions of patients with psoriasis vulgaris
    • Zhu K, Ye J, Wu M, Cheng H: Expression of Th1 and Th2 cytokine-associated transcription factors, T-bet and GATA-3, in peripheral blood mononuclear cells and skin lesions of patients with psoriasis vulgaris. Arch Dermatol Res 2010; 302: 517-523.
    • (2010) Arch Dermatol Res , vol.302 , pp. 517-523
    • Zhu, K.1    Ye, J.2    Wu, M.3    Cheng, H.4
  • 5
    • 7044224867 scopus 로고    scopus 로고
    • + T cells and the control of autoimmune disease
    • DOI 10.1016/j.coi.2004.09.015, PII S0952791504001608
    • Wraith DC, Nicolson KS, Whitley NT: Regulatory CD4+ T cells and the control of autoimmune disease. Curr Opin Immunol 2004; 16: 695-701. (Pubitemid 39423656)
    • (2004) Current Opinion in Immunology , vol.16 , Issue.6 , pp. 695-701
    • Wraith, D.C.1    Nicolson, K.S.2    Whitley, N.T.3
  • 6
    • 78649526238 scopus 로고    scopus 로고
    • Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases
    • Buckner JH: Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases. Nat Rev Immunol 2010; 10: 849-859.
    • (2010) Nat Rev Immunol , vol.10 , pp. 849-859
    • Buckner, J.H.1
  • 8
    • 77954054512 scopus 로고    scopus 로고
    • Regulation of cytokines by small RNAs during skin inflammation
    • Bak RO, Mikkelsen JG: Regulation of cytokines by small RNAs during skin inflammation. J Biomed Sci 2010; 17: 53.
    • (2010) J Biomed Sci , vol.17 , pp. 53
    • Bak, R.O.1    Mikkelsen, J.G.2
  • 10
    • 27544490377 scopus 로고    scopus 로고
    • + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • DOI 10.1038/ni1254, PII N1254
    • Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT: Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6: 1123-1132. (Pubitemid 41541790)
    • (2005) Nature Immunology , vol.6 , Issue.11 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 11
    • 33646164439 scopus 로고    scopus 로고
    • Expanding the effector CD4 T-cell repertoire: The Th17 lineage
    • Harrington LE, Mangan PR, Weaver CT: Expanding the effector CD4 T-cell repertoire: the Th17 lineage. Curr Opin Immunol 2006; 18: 349-356.
    • (2006) Curr Opin Immunol , vol.18 , pp. 349-356
    • Harrington, L.E.1    Mangan, P.R.2    Weaver, C.T.3
  • 16
    • 79959255489 scopus 로고    scopus 로고
    • Th22 in inflammatory and autoimmune disease: Prospects for therapeutic intervention
    • Zhang N, Pan HF, Ye DQ: Th22 in inflammatory and autoimmune disease: prospects for therapeutic intervention. Mol Cell Biochem 2011; 353: 41-46.
    • (2011) Mol Cell Biochem , vol.353 , pp. 41-46
    • Zhang, N.1    Pan, H.F.2    Ye, D.Q.3
  • 18
    • 3442877078 scopus 로고    scopus 로고
    • Systemic treatment with either cyclosporin A or methotrexate does not influence the T helper 1/T helper 2 balance in psoriatic patients
    • DOI 10.1023/B:JOCI.0000029107.47085.1b
    • Rentenaar RJ, Heydendael VM, van Diepen FN, de Rie MA, ten Berge IJ: Systemic treatment with either cyclosporin A or methotrexate does not influence the T helper 1/T helper 2 balance in psoriatic patients. J Clin Immunol 2004; 24: 361-369. (Pubitemid 39005568)
    • (2004) Journal of Clinical Immunology , vol.24 , Issue.4 , pp. 361-369
    • Rentenaar, R.J.1    Heydendael, V.M.R.2    Van Diepen, F.N.J.3    De Rie, M.A.4    Ten Berge, I.J.M.5
  • 19
    • 61849168497 scopus 로고    scopus 로고
    • Serum levels of IL-17 and IL-22 are reduced by etanercept, but not by acitretin, in patients with psoriasis: A randomized-controlled trial
    • Caproni M, Antiga E, Melani L, Volpi W, Del Bianco E, Fabbri P: Serum levels of IL-17 and IL-22 are reduced by etanercept, but not by acitretin, in patients with psoriasis: a randomized-controlled trial. J Clin Immunol 2009; 29: 210-214.
    • (2009) J Clin Immunol , vol.29 , pp. 210-214
    • Caproni, M.1    Antiga, E.2    Melani, L.3    Volpi, W.4    Del Bianco, E.5    Fabbri, P.6
  • 24
    • 52649167708 scopus 로고    scopus 로고
    • CD4 T cells: Fates, functions, and faults
    • Zhu J, Paul WE: CD4 T cells: fates, functions, and faults. Blood 2008; 112: 1557-1569.
    • (2008) Blood , vol.112 , pp. 1557-1569
    • Zhu, J.1    Paul, W.E.2
  • 25
    • 77958611660 scopus 로고    scopus 로고
    • Peripheral CD4 T cell differentiation regulated by networks of cytokines and transcriptors factors
    • Zhu J, Paul WE: Peripheral CD4 T cell differentiation regulated by networks of cytokines and transcriptors factors. Immunol Rev 2010; 238: 247-262.
    • (2010) Immunol Rev , vol.238 , pp. 247-262
    • Zhu, J.1    Paul, W.E.2
  • 26
    • 77952467331 scopus 로고    scopus 로고
    • Heterogeneity of human effector CD4+ T cells
    • Annunziato F, Romagni S: Heterogeneity of human effector CD4+ T cells. Arthritis Res Ther 2009; 11: 257.
    • (2009) Arthritis Res Ther , vol.11 , pp. 257
    • Annunziato, F.1    Romagni, S.2
  • 27
    • 58849104422 scopus 로고    scopus 로고
    • GATA3 and T-cell lineage: Essential functions before and after Thelper-2-cell differentiation
    • Ho IC, Tai TS, Pai SY: GATA3 and T-cell lineage: essential functions before and after Thelper-2-cell differentiation. Nat Rev Immunol 2009; 9: 125-135.
    • (2009) Nat Rev Immunol , vol.9 , pp. 125-135
    • Ho, I.C.1    Tai, T.S.2    Pai, S.Y.3
  • 30
    • 76149102966 scopus 로고    scopus 로고
    • Comparison of two etanercept regimens for treatment of psoriasis and psoriatic arthritis: PRESTA randomised double blind multicentric trial
    • Sterry W, Ortonne JP, Kirkham B, Brocq O, Robertson D, Pedersen RD, Estojak J, Molta CT, Freundlich B: Comparison of two etanercept regimens for treatment of psoriasis and psoriatic arthritis: PRESTA randomised double blind multicentric trial. BMJ 2010; 340:c147.
    • (2010) BMJ , vol.340
    • Sterry, W.1    Ortonne, J.P.2    Kirkham, B.3    Brocq, O.4    Robertson, D.5    Pedersen, R.D.6    Estojak, J.7    Molta, C.T.8    Freundlich, B.9
  • 31
    • 27644565806 scopus 로고    scopus 로고
    • Serum Levels of TNF-α, IFN-γ, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity
    • Ozer A, Murat Aral SS, Pinar C: Serum Levels of TNF-α, IFN-γ, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. Mediators Inflamm 2005: 5:273-279.
    • (2005) Mediators Inflamm , vol.5 , pp. 273-279
    • Ozer, A.1    Murat Aral, S.S.2    Pinar, C.3
  • 37
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • DOI 10.1038/383787a0
    • Abbas AK, Murphy KM, Sher A: Functional diversity of helper T lymphocytes. Nature 1996; 383: 787-793. (Pubitemid 26372655)
    • (1996) Nature , vol.383 , Issue.6603 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 38
    • 0028179006 scopus 로고
    • Lymphocyte responses and cytokines
    • DOI 10.1016/0092-8674(94)90332-8
    • Paul WE, Seder RA: Lymphocyte responses and cytokines. Cell 1994; 76: 241-251. (Pubitemid 24046687)
    • (1994) Cell , vol.76 , Issue.2 , pp. 241-251
    • Paul, W.E.1    Seder, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.