Expression of keratin 19, Na-K-Cl cotransporter and estrogen receptor alpha in developing mammary glands of ewes

Histology and Histopathology

Volumn 26, Issue 12, 2011, Pages 1563-1573

  Colitti, Monica ^a  

^a UNIVERSITY OF UDINE   (Italy)

Author keywords

CK19; ER ; Mammary glands; NKCC1; Sheep

Indexed keywords

CYTOKERATIN 19; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1 PROTEIN; SODIUM-POTASSIUM-CHLORIDE COTRANSPORTER 1 PROTEIN;

AGE; AGING; ANIMAL; ARTICLE; BIRTH; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IN SITU HYBRIDIZATION; LACTATION; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEEP; UDDER;

AGE FACTORS; AGING; ANIMALS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; KERATIN-19; LACTATION; MAMMARY GLANDS, ANIMAL; PARTURITION; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SHEEP; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; TRANSCRIPTION, GENETIC;

ANIMALIA; OVIS ARIES;

EID: 80053937214     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Bustin S.A., Benes V., Garson J.A., Hellemans J., Huggett J., Kubista M., Mueller R., Nolan T., Pfaffl M.W., Shipley G.L., Vandesompele J. and Wittwe C.T. (2009). The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 55, 611-622.
2. Capuco A.V. (2007). Identification of putative bovine mammary epithelial stem cells by their retention of labelled DNA strands. Exp. Biol. Med. 232, 1381-1390.
3. Capuco A.V., Ellis S., Wood D.L., Akers R.M. and Garrett W. (2002). Postnatal mammary ductal growth: three-dimensional imaging of cell proliferation, effects of estrogen treatment, and expression of steroid receptors in prepubertal calves. Tissue Cell 34, 143-154.
4. Chang G., Li Y., Omoto Y., Wang Y., Berg T., Nord M., Vihko P., Warner M., Piao Y.S. and Gustafsson J.A. (2005). Differential regulation of estrogen receptor (ER)· and ER, in primate mammary gland. J. Clin. Endocrinol. Metabol. 90, 435-444.
5. Clarke R.B. (2006). Ovarian steroids and the human breast: regulation of stem cells and cell proliferation. Maturitas 54, 327-334.
6. Clarke R.B., Anderson E., Howell A. and Potten C.S. (2003). Regulation of human breast epithelial stem cells. Cell Prolif. 36, 45-58.
7. Clarke R.B., Howell A., Potten C.S. and Anderson E. (1997). Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res. 57, 4987-4991.
8. Clarke R.B., Spence K., Anderson E., Howell A., Okano H. and Potten C.S. (2005). A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev. Biol. 277, 443-456.
9. Colitti M. (2010). Expression of putative stem cell markers related to developmental stage of sheep mammary glands. Anat. Histol. Embryol. 39, 555-562.
10. Colitti M. and Farinacci M. (2009a). Cell turnover and gene activities in sheep mammary glands prior to lambing to involution. Tissue Cell 41, 326-333.
11. Colitti M. and Farinacci M. (2009b). Expression of a putative stem cell marker, Musashi 1, in mammary glands of ewes. J. Mol. Hist. 40, 139-149.
12. Colitti M. and Pulina G. (2010). Expression profile of caseins, estrogen and prolactin receptors in mammary glands of dairy ewes. Ital. J. Anim. Sci. 9, 285-289.
13. D'Andrea L., Lytle C., Matthews J.B. Hofman P., Forbush B. 3rd and Madara J.L. (1996). Na:K:2Cl cotransporter (NKCC) of intestinal epithelial cells. Surface expression in response to cAMP. J. Biol. Chem. 271, 28969-28976.
14. Ellis S. and Capuco A.V. (2002). Cell proliferation in bovine mammary epithelium: identification of the primary proliferative cell population. Tissue Cell 34, 155-163.
15. Fendrick J.L., Raafat A.M. and Haslam S.Z. (1998). Mammary gland growth and development from the postnatal period to postmenopause: ovarian steroid receptor ontogeny and regulation in the mouse. J. Mammary Gland Biol. Neoplasia 3, 7-22.
16. Feng Y., Manka D., Wagner K.U. and Khan S.A. (2007). Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice. Proc. Natl. Acad. Sci. 104, 14718-14723.
17. Fridriksdottir A.J., Villadsen R., Gudjonsson T. and Petersen O.W. (2005). Maintenance of cell type diversification in the human breast. J. Mammary Gland Biol. Neoplasia 10, 61-74.
18. Gamba G., Saltzberg S.N., Lombardi M., Miyanoshita A., Lytton J., Hediger M.A., Brenner B.M. and Hebert S.C. (1993). Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc. Natl. Acad. Sci. 90, 2749-2753.
19. Gudjonsson T., Villadsen R., Nielsen H.L., Ronnov-Jessen L., Bissell M.J. and Petersen O.W. (2002). Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. Genes Dev. 16, 693-706.
20. Haslam S.Z. and Nummy K.A. (1992). The ontogeny and cellular distribution of estrogen receptors in normal mouse mammary gland. J. Steroid Biochem. Mol. Biol. 42, 589-595.
21. Hiraoka K., Miyazaki H., Niisato N., Iwasaki Y., Kawauchi A., Miki T. and Marunaka Y. (2010). Chloride ion modulates cell proliferation of human androgen-independent prostatic cancer cell. Cell Physiol. Biochem. 25, 379-388.
22. Hudson D.L., Guy A.T., Fry P., O'Hare M.J., Watt F.M. and Masters J.R. (2001). Epithelial cell differentiation pathways in the human prostate: identification of intermediate phenotypes by keratin expression. J. Histochem. Cytochem. 49, 271-278.
23. Li S., Han B., Liu G., Li S., Ouellet J., Labrie F. and Pelletier G. (2010). Immunocytochemical localization of sex steroid hormone receptors in normal human mammary gland. J. Histochem. Cytochem. 58, 509-515.
24. Meyer M.J., Rhoads R.P., Capuco A.V., Connor E.E., Hummel A., Boisclair Y.R. and Van Amburgh M.E. (2007). Ontogenic and nutritional regulation of steroid receptor and IGF-I transcript abundance in the prepubertal heifer mammary gland. J. Endocrinol. 195, 59-66.
25. Okano H., Imai T. and Okabe M. (2002). Musashi: a translational regulator of cell fate. J. Cell Sci. 115, 1355-1359.
26. O'Neill W.C. and Klein J.D. (1992). Regulation of vascular endothelial cell volume by Na-K-2Cl cotransport. Am. J. Physiol. 262 (2 Pt 1), C436-444.
27. Pfaffl M.W. (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29: e45.
28. Panet R., Marcus M. and Atlan H. (2000). Overexpression of the Na(+)/K(+)/Cl(-) cotransporter gene induces cell proliferation and phenotypic transformation in mouse fibroblasts. J. Cell Physiol. 182, 109-118.
29. Robinson T.L., Sutherland L.A. and Sutherland J. (2007). Validation of candidate bovine reference genes for use with real-time PCR. Vet. Immunol. Immunopathol. 115, 160-165.
30. Rozen S. and Skaletsky H.J. (2000). Primer3 on the WWW for general users and for biologist programmers. Bioinformatics Methods and Protocols: Methods in Molecular Biology. Humana Press. pp 365-386.
31. Schams D., Kohlenberg S., Amselgruber W., Berisha B., Pfaffl M.W. and Sinowatz F. (2003). Expression and localisation of oestrogen and progesterone receptors in the bovine mammary gland during development, function and involution. J. Endocrinol. 177, 305-317.
32. Shillingford J.M., Miyoshi K., Flagella M., Shull G.E. and Hennighausen L. (2002). Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis. Mol. Endocrinol. 16, 1309-1321.
33. Shillingford J.M., Miyoshi K., Robinson G.W., Bierie B., Cao Y., Karin M. and Hennighausen L. (2003). Proteotyping of mammary tissue from transgenic and gene knockout mice with immunohistochemical markers: a tool to define developmental lesions. J. Histochem. Cytochem. 51, 555-565.
34. Sleeman K.E., Kendrick H., Robertson D., Isacke C.M., Ashworth A. and Smalley M.J. (2007). Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. J. Cell Biol. 176, 19-26.
35. Smith G.H. and Chepko G. (2001). Mammary epithelial stem cells. Microsc. Res. Tech. 52, 190-203.
36. SPSS® Statistical Package for Social Science SPSS, 1997. Advanced Statistics 7.5. SPSS Inc., Chicago, IL.
37. Stasiak P.C., Purkis P.E., Leigh I.M. and Lane E.B. (1989). Keratin 19: predicted amino acid sequence and broad tissue distribution suggest it evolved from keratinocyte keratins. J. Invest. Dermatol. 92, 707-716.
38. Stefanon B., Colitti M., Gabai G., Knight C.H. and Wilde C.J. (2002). Mammary apoptosis and lactation persistency in dairy animals. J. Dairy Res. 69, 37-52.
39. Stingl J., Raouf A., Eirew P. and Eaves C.J. (2006). Deciphering the mammary epithelial cell hierarchy. Cell Cycle 5, 1519-1522.
40. Suzuki R., Atherton A.J., O'Hare M.J., Entwistle A., Lakhani S.R. and Clarke C. (2000). Proliferation and differentiation in the human breast during pregnancy. Differentiation 66:106-115.
41. Wang X.Y., Yin Y., Yuan H., Sakamaki T., Okano H. and Glazer R.I. (2008). Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch Pathways. Mol. Cell. Biol. 28, 3589-3599.
42. Welm B., Behbod F., Goodell M.A. and Rosen J.M. (2003). Isolation and characterization of functional mammary gland stem cells. Cell Prolif. 36, 17-32.
43. Woodward W.A., Chen M.S., Behbod F. and Rosen J.M. (2005). On mammary stem cells. J. Cell Sci. 118, 3585-3594.
44. Zhou S., Schuetz J.D., Bunting K.D., Colapietro A.M., Sampath J., Morris J.J., Lagutina I., Grosveld G.C., Osawa M., Nakauchi H. and Sorrentino B.P. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7, 1028-1034.