Virulence of pandemic (H1N1) 2009 influenza A polymerase reassortant viruses

Virulence

Volumn 2, Issue 5, 2011, Pages 422-426

  Song, Min Suk ^a   Pascua, Philippe Noriel Q ^a   Choi, Young Ki ^a  

^a Chungbuk National University College of Medicine   (South Korea)

Author keywords

Compatibility; Genetic evolution; Influenza A virus; Pandemic; Viral polymerases; Virulence

Indexed keywords

2009 H1N1 INFLUENZA; ARTICLE; GENETIC REASSORTMENT; GENETIC STABILITY; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INOCULATION; MORTALITY; NONHUMAN; REVERTANT; SURVIVAL RATE; VIRUS MUTATION; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALIA; INFLUENZA A VIRUS; MUS;

EID: 80053930563     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: 10.4161/viru.2.5.17267     Document Type: Article

References (30)

1. Cohen J, Enserink M, Swine flu. After delays, WHO agress: the 2009 pandemic ha begun. Science 2009; 324: 1469-1467; PMID: 19541958; http://dx.doi.org/10.1126./science.324-1496
2. Dawood FS, Jain S, Finelli L, Shaw MW, Lindstron S, Garren RJ, et al. Energence of a novel swineorigin influenza A(H1N1) viru;s in humans. N Engl J Med 2009; 360: 2605-2615; PMID:19423869; http://dx.doi.org/10.1056/NEMoa0903810.
3. Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, et al. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature 2009; 460:1021-1025; PMID:19672242; http://dx.doi.org/10.1038/nature08260.
4. Maines TR, Jayaraman A, Belser JA, Wadford DA, Pappas C, Zeng H, et al. Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice. Science 2009; 325:484-487; PMID:19574347; http://dx.doi.org/10.1126/science.1177238.
5. Munster VJ, de Wit E, van den Brand JM, Herfst S, Schrauwen EJ, Bestebroer TM, et al. Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. Science 2009; 325:481-483; PMID:19574348; http://dx.doi.org/10.1126/science.1177127.
6. Nicholls H. Pandemic influenza: the inside story. PLoS Biol 2006; 4:50; PMID:16464130; http://dx.doi.org/10.1371/journal.pbio.0040050.
7. Webster RG, Bean WJ, Gorman OT, Chambers TM, Kawaoka Y. Evolution and ecology of influenza A viruses. Microbiol Rev 1992; 56:152-179;PMID:1579108.
8. Chen H, Bright RA, Subbarao K, Smith C, Cox NJ, Katz JM, et al. Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice. Virus Res 2007; 128:159-163; PMID:17521765; http://dx.doi.org/10.1016/j.virusres.2007.04.017.
9. Neumann G, Noda T, Kawaoka Y. Emergence and pandemic potential of swine-origin H1N1 influenza virus. Nature 2009; 459:931-939; PMID:19525932; http://dx.doi.org/10.1038/nature08157.
10. Engelhardt OG, Fodor E. Functional association between viral and cellular transcription during influenza virus infection. Rev Med Virol 2006; 16:329-345; PMID:16933365; http://dx.doi.org/10.1002/rmv.512.
11. Hatta M, Gao P, Halfmann P, Kawaoka Y. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science 2001; 293:1840-1842; PMID:11546875; http://dx.doi.org/10.1126/science.1062882.
12. Labadie K, Dos Santos AE, Rameix-Welti MA, van der Werf S, Naffakh N. Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells. Virology 2007; 362:271-282; PMID:17270230; http://dx.doi.org/10.1016/j.virol.2006.12.027.
13. Subbarao EK, London W, Murphy BR. A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. J Virol 1993; 67:1761-1764; PMID:8445709.
14. Chen W, Calvo PA, Malide D, Gibbs J, Schubert U, Bacik I, et al. A novel influenza A virus mitochondrial protein that induces cell death. Nat Med 2001; 7:1306-1312; PMID:11726970; http://dx.doi.org/10.1038/nm1201-306.
15. Zamarin D, Ortigoza MB, Palese P. Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice. J Virol 2006; 80:7976-7983; PMID:16873254; http://dx.doi.org/10.1128/JVI.00415-06.
16. Song MS, Pascua PN, Lee JH, Baek YH, Lee OJ, Kim CJ, et al. The polymerase acidic protein gene of influenza a virus contributes to pathogenicity in a mouse model. J Virol 2009; 83:12325-12335; PMID:19793828; http://dx.doi.org/10.1128/JVI.01373-09.
17. Song MS, Pascua PN, Lee JH, Baek YH, Park KJ, Kwon HI, et al. Virulence and genetic compatibility of polymerase reassortant viruses derived from the pandemic (H1N1) 2009 influenza virus and circulating influenza A viruses. J Virol 2011; 85:6275-6286; PMID:21507962; http://dx.doi.org/10.1128/JVI.02125-10.
18. Hai R, Schmolke M, Varga ZT, Manicassamy B, Wang TT, Belser JA, et al. PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models. J Virol 2010; 84:4442-4450; PMID:20181699; http://dx.doi.org/10.1128/JVI.02717-09.
19. Herfst S, Chutinimitkul S, Ye J, de Wit E, Munster VJ, Schrauwen EJ, et al. Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission. J Virol 2010; 84:3752-3758; PMID:20130063; http://dx.doi.org/10.1128/JVI.02634-09.
20. Zhu H, Wang J, Wang P, Song W, Zheng Z, Chen R, et al. Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice. Virology 2010; 401:1-5; PMID:20303563; http://dx.doi.org/10.1016/j.virol.2010.02.024.
21. Castrucci MR, Donatelli I, Sidoli L, Barigazzi G, Kawaoka Y, Webster RG. Genetic reassortment between avian and human influenza A viruses in Italian pigs. Virology 1993; 193:503-506; PMID:8438586; http://dx.doi.org/10.1006/viro.1993.1155.
22. Scholtissek C. Molecular evolution of influenza viruses. Virus Genes 1995; 11:209-215; PMID:8828147; http://dx.doi.org/10.1007/BF01728660.
23. Schrauwen EJ, Herfst S, Chutinimitkul S, Bestebroer TM, Rimmelzwaan GF, Osterhaus AD, et al. Possible increased pathogenicity of pandemic (H1N1) 2009 influenza virus upon reassortment. Emerg Infect Dis 2011; 17:200-208; PMID:21291589; http://dx.doi.org/10.3201/eid1702.101268.
24. Octaviani CP, Ozawa M, Yamada S, Goto H, Kawaoka Y. High level of genetic compatibility between swine-origin H1N1 and highly pathogenic avian H5N1 influenza viruses. J Virol 2010; 84:10918-10922; PMID:20686037; http://dx.doi.org/10.1128/JVI.01140-10.
25. Bussey KA, Desmet EA, Mattiacio JL, Hamilton A, Bradel-Tretheway B, Bussey HE, et al. PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells. J Virol 2011; 85:7020-7028; PMID:21561908; http://dx.doi.org/10.1128/JVI.00522-11.
26. Chutinimitkul S, Herfst S, Steel J, Lowen AC, Ye J, van Riel D, et al. Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding. J Virol 2010; 84:11802-11813; PMID:20844044; http://dx.doi.org/10.1128/JVI.01136-10.
27. Kitikoon P, Sreta D, Nuntawan NaAS, Wongphatcharachai M, Lapkuntod J, Prakairungnamthip D, et al. Brief report: molecular characterization of a novel reassorted pandemic H1N1 2009 in Thai pigs. Virus Genes 2011; 43:1-5; PMID:21442301; http://dx.doi.org/10.1007/s11262-011-0597-5.
28. Starick E, Lange E, Fereidouni S, Bunzenthal C, Hoveler R, Kuczka A, et al. Reassorted pandemic (H1N1) 2009 influenza A virus discovered from pigs in Germany. J Gen Virol 2011; 92:1184-1188; PMID:21307227; http://dx.doi.org/10.1099/vir.0.028662-0.
29. Vijaykrishna D, Poon LL, Zhu HC, Ma SK, Li OT, Cheung CL, et al. Reassortment of pandemic H1N1/2009 influenza A virus in swine. Science 2010; 328:1529; PMID:20558710; http://dx.doi.org/10.1126/science.1189132.
30. Sun Y, Qin K, Wang J, Pu J, Tang Q, Hu Y, et al. High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses. Proc Natl Acad Sci USA 2011; 108:4164-4169; PMID:21368167; http://dx.doi.org/10.1073/pnas.1019109108.