Intratracheal administration of fullerene nanoparticles activates splenic CD11b+ cells

Journal of Hazardous Materials

Volumn 194, Issue , 2011, Pages 324-330

  Ding, Ning ^a,e   Kunugita, Naoki ^b   Ichinose, Takamichi ^c   Song, Yuan ^a,e   Yokoyama, Mitsuru ^d,e   Arashidani, Keiichi ^d,e   Yoshida, Yasuhiro ^a,e  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^c OITA UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Japan)

^d UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^e NONE   (Japan)

Author keywords

CDK2; Fullerenes; NF B; Splenocytes

Indexed keywords

IMMUNE SYSTEM; MAMMALS; NANOPARTICLES;

ANIMAL MODEL; CDK2; DAILY LIVES; FULLERENE NANOPARTICLES; INFLAMMATORY PROCESS; INTRATRACHEAL; LUNG TISSUE; SPLENOCYTES;

FULLERENES;

CD11B ANTIGEN; CYCLIN DEPENDENT KINASE 2; FULLERENE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; NANOPARTICLE; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA;

CYTOLOGY; FULLERENE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNE SYSTEM; INDUCED RESPONSE; NANOTECHNOLOGY; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; IMMUNE SYSTEM; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; SPLEEN CELL; SPLEEN DISEASE; SPLENIC INFLAMMATION; WESTERN BLOTTING;

ANIMALIA; MUS;

EID: 80053913308     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2011.07.101     Document Type: Article

References (32)

1. Morimoto Y., Hirohashi M., Ogami A., et al. Inflammogenic effect of well-characterized fullerenes in inhalation and intratracheal instillation studies. Part Fibre Toxicol. 2010, 7:4.
2. Baker G.L., Gupta A., Clark M.L., et al. Inhalation toxicity and lung toxicokinetics of C60 fullerene nanoparticles and microparticles. Toxicol. Sci. 2008, 101:122-131.
3. Mercer R.R., Scabilloni J., Wang L., et al. Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008, 294:L87-L97.
4. Bosi S., Da Ros T., Spalluto G., Prato M. Fullerene derivatives: an attractive tool for biological applications. Eur. J. Med. Chem. 2003, 38:913-923.
5. Johnston H.J., Hutchison G.R., Christensen F.M., Aschberger K., Stone V. The biological mechanisms and physicochemical characteristics responsible for driving fullerene toxicity. Toxicol. Sci. 2010, 114:162-182.
6. Wan F., Lenardo M.J. The nuclear signaling of NF-kappaB: current knowledge, new insights, and future perspectives. Cell Res. 2009, 20:24-33.
7. Karin M., Lin A. NF-kappaB at the crossroads of life and death. Nat. Immunol. 2002, 3:221-227.
8. Murray A.W. Recycling the cell cycle: cyclins revisited. Cell 2004, 116:221-234.
9. Obaya A.J., Sedivy J.M. Regulation of cyclin-Cdk activity in mammalian cells. Cell. Mol. Life Sci. 2002, 59:126-142.
10. Macian F. NFAT proteins: key regulators of T-cell development and function. Nat. Rev. Immunol. 2005, 5:472-484.
11. Linse S., Cabaleiro-Lago C., Xue W.F., et al. Nucleation of protein fibrillation by nanoparticles. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:8691-8696.
12. Yoshida Y., Wang M.Q., Liu J.N., Shan B.E., Yamashita U. Immunomodulating activity of Chinese medicinal herbs and Oldenlandia diffusa in particular. Int. J. Immunopharmacol. 1997, 19:359-370.
13. Liu J., Yoshida Y., Yamashita U. Suppressive effect of reactive oxygen species on CD40-induced B cell activation. FEBS Lett. 2007, 581:5043-5049.
14. Yoshida Y., Liu J., Sugiura T., et al. The indoor air pollutant 2-ethyl-hexanol activates CD4 cells. Chem. Biol. Interact. 2009, 177:137-141.
15. Yoshida Y., Kumar A., Koyama Y., et al. Interleukin 1 activates STAT3/nuclear factor-kappaB cross-talk via a unique TRAF6- and p65-dependent mechanism. J. Biol. Chem. 2004, 279:1768-1776.
16. Sayes C.M., Marchione A.A., Reed K.L., Warheit D.B. Comparative pulmonary toxicity assessments of C60 water suspensions in rats: few differences in fullerene toxicity in vivo in contrast to in vitro profiles. Nano Lett. 2007, 7:2399-2406.
17. Markovic Z., Trajkovic V. Biomedical potential of the reactive oxygen species generation and quenching by fullerenes (C60). Biomaterials 2008, 29:3561-3573.
18. Fujita K., Morimoto Y., Endoh S., et al. Identification of potential biomarkers from gene expression profiles in rat lungs intratracheally instilled with C(60) fullerenes. Toxicology 2010.
19. Johnston J.A., Bacon C.M., Finbloom D.S., et al. Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:8705-8709.
20. Andreakos E. Targeting cytokines in autoimmunity: new approaches, new promise. Expert Opin. Biol. Ther. 2003, 3:435-447.
21. Liu Y., Jiao F., Qiu Y., et al. The effect of Gd@C82(OH)22 nanoparticles on the release of Th1/Th2 cytokines and induction of TNF-alpha mediated cellular immunity. Biomaterials 2009, 30:3934-3945.
22. Liu Y., Jiao F., Qiu Y., et al. Immunostimulatory properties and enhanced TNF-alpha mediated cellular immunity for tumor therapy by C60(OH)20 nanoparticles. Nanotechnology 2009, 20:415102.
23. Naota M., Shimada A., Morita T., Inoue K., Takano H. Translocation pathway of the intratracheally instilled C60 fullerene from the lung into the blood circulation in the mouse: possible association of diffusion and caveolae-mediated pinocytosis. Toxicol. Pathol. 2009, 37:456-462.
24. Park E.J., Kim H., Kim Y., Yi J., Choi K., Park K. Carbon fullerenes (C60s) can induce inflammatory responses in the lung of mice. Toxicol. Appl. Pharmacol. 2010, 244:226-233.
25. Kleinman M.T., Araujo J.A., Nel A., et al. Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways. Toxicol. Lett. 2008, 178:127-130.
26. Malumbres M., Barbacid M. Mammalian cyclin-dependent kinases. Trends Biochem. Sci. 2005, 30:630-641.
27. Falck J., Mailand N., Syljuasen R.G., Bartek J., Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 2001, 410:842-847.
28. Mankan A.K., Lawless M.W., Gray S.G., Kelleher D., McManus R. NF-kappaB regulation: the nuclear response. J. Cell. Mol. Med. 2009, 13:631-643.
29. Manna S.K., Sarkar S., Barr J., et al. Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-kappaB in human keratinocytes. Nano Lett. 2005, 5:1676-1684.
30. Ding L., Stilwell J., Zhang T., et al. Molecular characterization of the cytotoxic mechanism of multiwall carbon nanotubes and nano-onions on human skin fibroblast. Nano Lett. 2005, 5:2448-2464.
31. Chou C.C., Hsiao H.Y., Hong Q.S., et al. Single-walled carbon nanotubes can induce pulmonary injury in mouse model. Nano Lett. 2008, 8:437-445.
32. Smith-Garvin J.E., Koretzky G.A., Jordan M.S. T cell activation. Annu. Rev. Immunol. 2009, 27:591-619.