Tobacco smoke regulates the expression and activity of microsomal prostaglandin e synthase-1: Role of prostacyclin and NADPH-oxidase

FASEB Journal

Volumn 25, Issue 10, 2011, Pages 3731-3740

  Barbieri, Silvia S ^a   Amadio, Patrizia ^b   Gianellini, Sara ^b   Zacchi, Elena ^b   Weksler, Babette B ^c   Tremoli, Elena ^a,b  

^a CENTRO CARDIOLOGICO MONZINO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Endothelial cells; Prostanoids; Reactive oxygen species; Signal transduction

Indexed keywords

APOLIPOPROTEIN E; CARBACYCLIN; CAY 10441; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; PROSTACYCLIN; PROSTACYCLIN DERIVATIVE; PROSTACYCLIN SYNTHASE; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; PROTEIN P47; PROTEIN P47PHOX; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; TOBACCO SMOKE; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; CIGARETTE SMOKING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE SILENCING; HEART MUSCLE CELL; IC 50; IMMUNOMODULATION; MALE; MOUSE; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TYROSINE NITRATION;

ANIMALS; BENZYL COMPOUNDS; CELL LINE; ENDOTHELIAL CELLS; EPOPROSTENOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMIDAZOLES; INTERLEUKIN-1BETA; INTRAMOLECULAR OXIDOREDUCTASES; MALE; MICE; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; SMOKE; TOBACCO;

MUS; NICOTIANA TABACUM;

EID: 80053899950     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-181776     Document Type: Article

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