-
1
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
-
Russell SM, Tayebi N, Nakajima H, et al. Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science. 1995;270(5237):797-800.
-
(1995)
Science
, vol.270
, Issue.5237
, pp. 797-800
-
-
Russell, S.M.1
Tayebi, N.2
Nakajima, H.3
-
2
-
-
33745713168
-
Activating alleles of JAK3 in acute megakaryoblastic leukemia
-
Walters DK, Mercher T, Gu TL, et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell. 2006;10(1):65-75.
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 65-75
-
-
Walters, D.K.1
Mercher, T.2
Gu, T.L.3
-
3
-
-
67249146555
-
JAK mutations in high-risk childhood acute lymphoblastic leukemia
-
Mullighan CG, Zhang J, Harvey RC, et al. JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2009;106(23):9414-9418.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.23
, pp. 9414-9418
-
-
Mullighan, C.G.1
Zhang, J.2
Harvey, R.C.3
-
4
-
-
80053638747
-
FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/ lymphoma
-
Elliott NE, Cleveland SM, Grann V, Janik J, Waldmann TA, Davé UP. FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/ lymphoma. Blood. 2011;118(14):3911-3921.
-
(2011)
Blood
, vol.118
, Issue.14
, pp. 3911-3921
-
-
Elliott, N.E.1
Cleveland, S.M.2
Grann, V.3
Janik, J.4
Waldmann, T.A.5
Davé, U.P.6
-
5
-
-
19944427133
-
The Janus kinases (Jaks)
-
Yamaoka K, Saharinen P, Pesu M, Holt VE III, Silvennoinen O, O'Shea JJ. The Janus kinases (Jaks). Genome Biol. 2004;5(12):253.
-
(2004)
Genome Biol
, vol.5
, Issue.12
, pp. 253
-
-
Yamaoka, K.1
Saharinen, P.2
Pesu, M.3
Holt III, V.E.4
Silvennoinen, O.5
O'Shea, J.J.6
-
6
-
-
18244393495
-
Unexpected effects of FERM domain mutations on catalytic activity of Jak3: Structural implication for Janus kinases
-
DOI 10.1016/S1097-2765(01)00398-7
-
Zhou YJ, Chen M, Cusack NA, et al. Unexpected effects of FERM domain mutations on catalytic activity of Jak3: structural implication for Janus kinases. Mol Cell. 2001;8(5):959-969. (Pubitemid 34031799)
-
(2001)
Molecular Cell
, vol.8
, Issue.5
, pp. 959-969
-
-
Zhou, Y.-J.1
Chen, M.2
Cusack, N.A.3
Kimmel, L.H.4
Magnuson, K.S.5
Boyd, J.G.6
Lin, W.7
Roberts, J.L.8
Lengi, A.9
Buckley, R.H.10
Geahlen, R.L.11
Candotti, F.12
Gadina, M.13
Changelian, P.S.14
O'Shea, J.J.15
-
7
-
-
0242332186
-
Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor
-
DOI 10.1126/science.1087061
-
Changelian PS, Flanagan ME, Ball DJ, et al. Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Science. 2003;302(5646):875- 878. (Pubitemid 37339629)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 875-878
-
-
Changelian, P.S.1
Flanagan, M.E.2
Ball, D.J.3
Kent, C.R.4
Magnuson, K.S.5
Martin, W.H.6
Rizzuti, B.J.7
Sawyer, P.S.8
Perry, B.D.9
Brissette, W.H.10
McCurdy, S.P.11
Kudlacz, E.M.12
Conklyn, M.J.13
Elliott, E.A.14
Koslov, E.R.15
Fisher, M.B.16
Strelevitz, T.J.17
Yoon, K.18
Whipple, D.A.19
Sun, J.20
Munchhof, M.J.21
Doty, J.L.22
Casavant, J.M.23
Blumenkopf, T.A.24
Hines, M.25
Brown, M.F.26
Lillie, B.M.27
Subramanyam, C.28
Shang-Poa, C.29
Milici, A.J.30
Beckius, G.E.31
Moyer, J.D.32
Su, C.33
Woodworth, T.G.34
Gaweco, A.S.35
Beals, C.R.36
Littman, B.H.37
Fisher, D.A.38
Smith, J.F.39
Zagouras, P.40
Magna, H.A.41
Saltarelli, M.J.42
Johnson, K.S.43
Nelms, L.F.44
Des, E.S.G.45
Hayes, L.S.46
Kawabata, T.T.47
Finco-Kent, D.48
Baker, D.L.49
Larson, M.50
Si, M.-S.51
Paniagua, R.52
Higgins, J.53
Holm, B.54
Reitz, B.55
Zhou, Y.-J.56
Morris, R.E.57
O'Shea, J.J.58
Borie, D.C.59
more..
-
8
-
-
79951482172
-
CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/ TSP
-
Ju W, Zhang M, Jiang JK, et al. CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/ TSP. Blood. 2011;117(6):1938-1946.
-
(2011)
Blood
, vol.117
, Issue.6
, pp. 1938-1946
-
-
Ju, W.1
Zhang, M.2
Jiang, J.K.3
-
9
-
-
75749127860
-
Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: Results from a randomised, double-blind, placebo-controlled trial
-
Coombs JH, Bloom BJ, Breedveld FC, et al. Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial. Ann Rheum Dis. 2010;69(2):413-416.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.2
, pp. 413-416
-
-
Coombs, J.H.1
Bloom, B.J.2
Breedveld, F.C.3
-
10
-
-
77956696835
-
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
-
Verstovsek S, Kantarjian H, Mesa RA, et al. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med. 2010;363(12):1117-1127.
-
(2010)
N Engl J Med
, vol.363
, Issue.12
, pp. 1117-1127
-
-
Verstovsek, S.1
Kantarjian, H.2
Mesa, R.A.3
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