Tumor necrosis factor-α downregulates sodium current in skeletal muscle by protein kinase c activation: Involvement in critical illness polyneuromyopathy

American Journal of Physiology - Cell Physiology

Volumn 301, Issue 5, 2011, Pages

  Guillouet, Maité ^a,b,c   Gueret, Gildas ^a,b,c   Rannou, Fabrice ^a,b   Giroux Metges, Marie Agnès ^a,b   Gioux, Maxime ^a,b   Arvieux, Charles C ^a,b,c   Pennec, Jean Pierre ^a,b  

^a FACULTÉ DE MÉDECINE ET DES SCIENCES DE LA SANTÉ   (France)

^b UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

^c BREST UNIVERSITY HOSPITAL   (France)

Author keywords

Muscle excitability; Sepsis; Voltage gated sodium channel

Indexed keywords

PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRITICAL ILLNESS; CRITICAL ILLNESS POLYNEUROMYOPATHY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; INHIBITION KINETICS; NEUROMUSCULAR DISEASE; NONHUMAN; PERONEUS LONGUS MUSCLE; PERONEUS MUSCLE; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; SODIUM CURRENT;

ANIMALS; BENZOPHENANTHRIDINES; CRITICAL ILLNESS; DOWN-REGULATION; ENZYME INHIBITORS; MEMBRANE POTENTIALS; MUSCLE FIBERS, SKELETAL; POLYNEUROPATHIES; PROTEIN KINASE C; RATS; RATS, WISTAR; SEPSIS; SODIUM; SODIUM CHANNELS; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 80053630039     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00097.2011     Document Type: Article

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