-
2
-
-
0034069651
-
Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2
-
Escayg, A. et al. Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2. Nature Genet. 24, 343-345 (2000).
-
(2000)
Nature Genet.
, vol.24
, pp. 343-345
-
-
Escayg, A.1
-
3
-
-
0035863416
-
A gain-of-function in the sodium channel gene Scn2a results in seizures and behavioral abnormalities
-
Keamey, J. A. et al. A gain-of-function in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience 102, 307-317 (2001).
-
(2001)
Neuroscience
, vol.102
, pp. 307-317
-
-
Keamey, J.A.1
-
4
-
-
14344277590
-
v1.2 in a patient with febrile and afebrile seizures causes channel dysfunction
-
v1.2 in a patient with febrile and afebrile seizures causes channel dysfunction. Proc. Natl Acad. Sci. USA 98, 6384-6389 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 6384-6389
-
-
Sugawara, T.1
-
5
-
-
0002078145
-
Autoantibody-mediated channelopathies at the neuromuscular junction
-
Newsom-Davis, J. Autoantibody-mediated channelopathies at the neuromuscular junction. Neuroscientist 3, 337-346 (1997).
-
(1997)
Neuroscientist
, vol.3
, pp. 337-346
-
-
Newsom-Davis, J.1
-
6
-
-
0031664943
-
Autoimmunity to glutamate receptors in Rasmussen's encephalitis: A rare finding or the tip of an iceberg?
-
Gahring, L. C. & Rogers, S. W. Autoimmunity to glutamate receptors in Rasmussen's encephalitis: a rare finding or the tip of an iceberg? Neuroscientist 4, 373-379 (1998).
-
(1998)
Neuroscientist
, vol.4
, pp. 373-379
-
-
Gahring, L.C.1
Rogers, S.W.2
-
7
-
-
0026490286
-
A Cellular and molecular biology of voltage-gated sodium channels
-
Catterall, W. A Cellular and molecular biology of voltage-gated sodium channels. Physiol. Rev. 72, 515-548 (1992).
-
(1992)
Physiol. Rev.
, vol.72
, pp. 515-548
-
-
Catterall, W.1
-
8
-
-
0345034603
-
Evolution and diversity of sodium channel genes
-
Plummer, W. & Meisler, M. H. Evolution and diversity of sodium channel genes. Genomes 57, 323-331 (1999). Reviews the structural differences between, and evolution of, the multiple sodium channels that have been cloned.
-
(1999)
Genomes
, vol.57
, pp. 323-331
-
-
Plummer, W.1
Meisler, M.H.2
-
9
-
-
0033636506
-
Nomenclature of voltage-gated sodium channels
-
Goldin, A. L et al. Nomenclature of voltage-gated sodium channels. Neuron 2, 365-368 (2000). Introduces a uniform nomenclature for voltage-gated sodium channels.
-
(2000)
Neuron
, vol.2
, pp. 365-368
-
-
Goldin, A.L.1
-
10
-
-
0034728403
-
The neuron as a dynamic electrogenic machine: Modulation of sodium channel expression as a basis for functional plasticity in neurons
-
Waxman, S. G. The neuron as a dynamic electrogenic machine: modulation of sodium channel expression as a basis for functional plasticity in neurons. Phil. Trans. R. Soc. Lond. B. 355, 199-213 (2000).
-
(2000)
Phil. Trans. R. Soc. Lond. B
, vol.355
, pp. 199-213
-
-
Waxman, S.G.1
-
11
-
-
0024810594
-
Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development
-
Beckh, S., Noda, M., Lubbert, H. & Numa, S. Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development. EMBO J. 8, 3611-3616 (1989).
-
(1989)
EMBO J.
, vol.8
, pp. 3611-3616
-
-
Beckh, S.1
Noda, M.2
Lubbert, H.3
Numa, S.4
-
12
-
-
0025739445
-
Regional and temporal expression of sodium channel messenger RNAs in the rat brain during development
-
Brysch, W. Creutzfeldt, O. W., Luno, K., Schlingensiepen, R. & Schlingensiepen, K.-H. Regional and temporal expression of sodium channel messenger RNAs in the rat brain during development. Exp. Brain Res. 86, 562-567 (1991).
-
(1991)
Exp. Brain Res.
, vol.86
, pp. 562-567
-
-
Brysch, W.1
Creutzfeldt, O.W.2
Luno, K.3
Schlingensiepen, R.4
Schlingensiepen, K.-H.5
-
13
-
-
0031127498
-
Sodium channel α-subunit mRNAs I, II, III, NaG, Na6 and hNE: Different expression patterns in developing rat nervous system
-
Felts, P. A., Yokoyama, S., Dib-Hajj, S., Black, J. A. & Waxman, S. G. Sodium channel α-subunit mRNAs I, II, III, NaG, Na6 and hNE: different expression patterns in developing rat nervous system. Brain Res. Mol. Brain Res. 45, 71-83 (1997).
-
(1997)
Brain Res. Mol. Brain Res.
, vol.45
, pp. 71-83
-
-
Felts, P.A.1
Yokoyama, S.2
Dib-Hajj, S.3
Black, J.A.4
Waxman, S.G.5
-
14
-
-
0032527590
-
The sodium channel Scn8a is the major contributor to the postnatal developmental increase of sodium current density in spinal motoneurons
-
Garcia, K. D., Sprunger, L. K., Meisler, M. M. & Beam, K. G. The sodium channel Scn8a is the major contributor to the postnatal developmental increase of sodium current density in spinal motoneurons. J. Neurosci. 18, 5234-5239 (1998).
-
(1998)
J. Neurosci.
, vol.18
, pp. 5234-5239
-
-
Garcia, K.D.1
Sprunger, L.K.2
Meisler, M.M.3
Beam, K.G.4
-
16
-
-
0031840375
-
Rescue of α-SNS/PN3 sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo
-
Dib-Hajj, S. D. et al. Rescue of α-SNS/PN3 sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. J. Neurophysiol. 79, 2668-2676 (1998).
-
(1998)
J. Neurophysiol.
, vol.79
, pp. 2668-2676
-
-
Dib-Hajj, S.D.1
-
17
-
-
0033062955
-
In vivo NGF deprivation reduces SNS/PN3 expression and TTX-R sodium currents in IB4-negative DRG neurons
-
Fjell, J., Cummins, T. R., Fried, K., Black, J. A. & Waxman, S. G. In vivo NGF deprivation reduces SNS/PN3 expression and TTX-R sodium currents in IB4-negative DRG neurons. J. Neurophysiol. 81, 803-911 (1999).
-
(1999)
J. Neurophysiol.
, vol.81
, pp. 803-911
-
-
Fjell, J.1
Cummins, T.R.2
Fried, K.3
Black, J.A.4
Waxman, S.G.5
-
18
-
-
0034554778
-
Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons
-
Cummins, T. R., Black, J. A., Dib-Hajj, S. D. & Waxman, S. G. Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons. J. Neurosci. 20, 8754-8761 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 8754-8761
-
-
Cummins, T.R.1
Black, J.A.2
Dib-Hajj, S.D.3
Waxman, S.G.4
-
19
-
-
0033586628
-
Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons
-
Fjell, J. et al. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons. Brain Res. Mol. Brain Res. 67, 267-282 (1999).
-
(1999)
Brain Res. Mol. Brain Res.
, vol.67
, pp. 267-282
-
-
Fjell, J.1
-
20
-
-
0034613153
-
Potent analgesic effects of GDNF in neuropathic pain states
-
Boucher, T. J. et al. Potent analgesic effects of GDNF in neuropathic pain states. Science 290, 124-127 (2000).
-
(2000)
Science
, vol.290
, pp. 124-127
-
-
Boucher, T.J.1
-
21
-
-
0024658704
-
Electrical activity, CAMP, and cytosolic calcium regulate mRNA encoding sodium channel a subunits in rat muscle cells
-
Offord, J. & Catterall, W. A. Electrical activity, CAMP, and cytosolic calcium regulate mRNA encoding sodium channel a subunits in rat muscle cells. Neuron 2, 1447-1452 (1989).
-
(1989)
Neuron
, vol.2
, pp. 1447-1452
-
-
Offord, J.1
Catterall, W.A.2
-
22
-
-
0030067809
-
+ channel β1 subunit mRNA in the olfactory system during postnatal development and following denervation
-
+ channel β1 subunit mRNA in the olfactory system during postnatal development and following denervation. J. Neurosci. 16, 702-714 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 702-714
-
-
Sashihara, S.1
Greer, C.A.2
Oh, Y.3
Waxman, S.G.4
-
23
-
-
0030979477
-
+ channel mRNA following sensory deprivation of tufted cells in the neonatal rat olfactory bulb
-
+ channel mRNA following sensory deprivation of tufted cells in the neonatal rat olfactory bulb. Neuroreport 8, 1289-1293 (1997).
-
(1997)
Neuroreport
, vol.8
, pp. 1289-1293
-
-
Sashihara, S.1
Waxman, S.G.2
Greer, C.A.3
-
24
-
-
0035025620
-
v1.6 at developing CNS nodes of Ranvier
-
v1.6 at developing CNS nodes of Ranvier. Neuron 30, 105-119 (2001).
-
(2001)
Neuron
, vol.30
, pp. 105-119
-
-
Kaplan, M.R.1
-
25
-
-
0020603035
-
Burst discharge in mammalian neuroendocrine cells involves an intrinsic regenerative mechanism
-
Andrew, R. D. & Dudek, F. E. Burst discharge in mammalian neuroendocrine cells involves an intrinsic regenerative mechanism. Science 221, 1050-1052 (1983).
-
(1983)
Science
, vol.221
, pp. 1050-1052
-
-
Andrew, R.D.1
Dudek, F.E.2
-
26
-
-
0027176849
-
Inward sodium current involvement in regenerative bursting activity of rat magnocellular supraoptic neurons in vitro
-
Inenaga, K., Nagamoto, T., Kannan, H. & Yamashita, H. Inward sodium current involvement in regenerative bursting activity of rat magnocellular supraoptic neurons in vitro. J. Physiol. (Lond.) 465, 289-301 (1993).
-
(1993)
J. Physiol. (Lond.)
, vol.465
, pp. 289-301
-
-
Inenaga, K.1
Nagamoto, T.2
Kannan, H.3
Yamashita, H.4
-
28
-
-
0033514492
-
Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input
-
Tanaka, M. et al. Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input. Proc. Natl Acad. Sci. USA 96, 1088-109 (1999). Demonstration of plasticity of sodium channel gene expression in the normal adult central nervous system.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 1088-1109
-
-
Tanaka, M.1
-
29
-
-
0001937431
-
-
eds Wall, P. D. & Melzack, R. Churchill Livingstone, Edinburgh
-
Devor, M. & Seltzer, Z. in Textbook of Pain 4th edn (eds Wall, P. D. & Melzack, R.) 129-164 (Churchill Livingstone, Edinburgh, 1999).
-
(1999)
Textbook of Pain 4th Edn
, pp. 129-164
-
-
Devor, M.1
Seltzer, Z.2
-
30
-
-
0030724424
-
Axotomy increases the excitability of dorsal root ganglion cells with unmyelinated axons
-
Zhang, J.-M., Donnelly, D. R. Song, X.-J. & LaMotte, R. H. Axotomy increases the excitability of dorsal root ganglion cells with unmyelinated axons. J. Neurophysiol. 78, 2790-2794 (1997).
-
(1997)
J. Neurophysiol.
, vol.78
, pp. 2790-2794
-
-
Zhang, J.-M.1
Donnelly, D.R.2
Song, X.-J.3
LaMotte, R.H.4
-
32
-
-
0020619654
-
Long-term regenerated nerve fibres retain sensitivity to potassium channel blocking agents
-
Kocsis, J. D. & Waxman, S. G. Long-term regenerated nerve fibres retain sensitivity to potassium channel blocking agents. Nature 304, 640-642 (1983). Demonstration of altered ion channel activity in previously injured nerves.
-
(1983)
Nature
, vol.304
, pp. 640-642
-
-
Kocsis, J.D.1
Waxman, S.G.2
-
33
-
-
0020505960
-
Maturation of mammalian myelinated fibers: Changes in action potential characteristics following 4-aminopyridine application
-
Kocsis, J. D., Ruiz, J. A. & Waxman, S. G. Maturation of mammalian myelinated fibers: changes in action potential characteristics following 4-aminopyridine application. J. Neurophysiol. 50, 449-463 (1983).
-
(1983)
J. Neurophysiol.
, vol.50
, pp. 449-463
-
-
Kocsis, J.D.1
Ruiz, J.A.2
Waxman, S.G.3
-
34
-
-
0030608445
-
Spinal sensory neurons express multiple sodium channel α-subunit mRNAs
-
Black, J. A. et al. Spinal sensory neurons express multiple sodium channel α-subunit mRNAs. Brain Res. Mol. Brain Res. 43, 117-132 (1996).
-
(1996)
Brain Res. Mol. Brain Res.
, vol.43
, pp. 117-132
-
-
Black, J.A.1
-
35
-
-
0030041548
-
A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
-
Akopian, A. N., Sivilotti, L & Wood, J. N. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons. Nature 379, 257-262 (1996).
-
(1996)
Nature
, vol.379
, pp. 257-262
-
-
Akopian, A.N.1
Sivilotti, L.2
Wood, J.N.3
-
36
-
-
13344294399
-
Structure and function of a novel voltage-gated tetrodotoxin-resistant sodium channel specific to sensory neurons
-
Sangameswaren, L et al. Structure and function of a novel voltage-gated tetrodotoxin-resistant sodium channel specific to sensory neurons. J. Biol. Chem. 271, 5953-5956 (2000).
-
(2000)
J. Biol. Chem.
, vol.271
, pp. 5953-5956
-
-
Sangameswaren, L.1
-
38
-
-
0029907091
-
Down-regulation of transcripts for Na channel α-SNS in spinal sensory neurons following axotomy
-
Dib-Hajj, S., Black, J. A., Felts, P. & Waxman, S. G. Down-regulation of transcripts for Na channel α-SNS in spinal sensory neurons following axotomy. Proc. Natl Acad. Sci. USA 93, 14950-14954 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 14950-14954
-
-
Dib-Hajj, S.1
Black, J.A.2
Felts, P.3
Waxman, S.G.4
-
39
-
-
0034307559
-
Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy
-
Sleeper, A. A. et al. Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy. J. Neurosci. 20, 7279-7289 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 7279-7289
-
-
Sleeper, A.A.1
-
40
-
-
0027933696
-
Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is re-expressed following axotomy
-
Waxman, S. G., Kocsis, J. D. & Black, J. A. Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is re-expressed following axotomy. J. Neurophysiol. 72, 466-471 (1994). References 38 and 40 report the dysregulation of sodium channel mRNA in peripherally axotomized DRG neurons. Reference 39 demonstrates parallel changes in the sodium channel proteins and currents.
-
(1994)
J. Neurophysiol.
, vol.72
, pp. 466-471
-
-
Waxman, S.G.1
Kocsis, J.D.2
Black, J.A.3
-
41
-
-
0032743734
-
Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons
-
Black, J. A. et al. Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons. J. Neurophysiol. 82, 2776-2785 (1999).
-
(1999)
J. Neurophysiol.
, vol.82
, pp. 2776-2785
-
-
Black, J.A.1
-
42
-
-
0030997916
-
Down-regulation of tetrodotoxin-resistant sodium currents and up-regulatbn of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons following nerve injury
-
Cummins, T. R. & Waxman, S. G. Down-regulation of tetrodotoxin-resistant sodium currents and up-regulatbn of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons following nerve injury. J. Neurosci. 17, 3503-3514 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 3503-3514
-
-
Cummins, T.R.1
Waxman, S.G.2
-
43
-
-
0035882277
-
v1.3 sodium channels: Rapid repriming and stow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons
-
v1.3 sodium channels: rapid repriming and stow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. J. Neurosci. 21, 5952-5961 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 5952-5961
-
-
Cummins, T.R.1
-
44
-
-
0346870557
-
GDNF and NGF reverse changes in repriming kinetics of TTX-S currents following peripheral axotomy of DRG neurons
-
in the press
-
Cummins, T. R. et al. GDNF and NGF reverse changes in repriming kinetics of TTX-S currents following peripheral axotomy of DRG neurons. Soc. Neurosci. Abstr. (in the press).
-
Soc. Neurosci. Abstr.
-
-
Cummins, T.R.1
-
45
-
-
0026608996
-
On the role of nerve growth factor in the development of myelinated nociceptors
-
Lewin, G. R., Ritter, A. M. & Mendel, L. M. On the role of nerve growth factor in the development of myelinated nociceptors. J. Neurosci. 12, 1896-1905 (1992).
-
(1992)
J. Neurosci.
, vol.12
, pp. 1896-1905
-
-
Lewin, G.R.1
Ritter, A.M.2
Mendel, L.M.3
-
46
-
-
0027050717
-
Soma membrane properties of physiologically identified sensory neurons in the rat: Effects of nerve growth factor
-
Ritter, A. M. & Mendel, L. M. Soma membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor. J. Neurophysiol. 68, 2033-2041 (1992).
-
(1992)
J. Neurophysiol.
, vol.68
, pp. 2033-2041
-
-
Ritter, A.M.1
Mendel, L.M.2
-
47
-
-
0032723079
-
Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain
-
Dib-Hajj, S. D. et al. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain 83, 591-600 (1999).
-
(1999)
Pain
, vol.83
, pp. 591-600
-
-
Dib-Hajj, S.D.1
-
48
-
-
0033529222
-
Sodium channels and pain
-
Waxman, S. G., Dib-Hajj, S., Cummins, T. R. & Black, J. A. Sodium channels and pain. Proc. Natl Acad. Sci. USA 96, 7635-7639 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 7635-7639
-
-
Waxman, S.G.1
Dib-Hajj, S.2
Cummins, T.R.3
Black, J.A.4
-
49
-
-
0023072631
-
Ionic channel organization of normal and regenerating mammalian axons
-
Kocsis, J. D. & Waxman, S. G. Ionic channel organization of normal and regenerating mammalian axons. Prog. Brain Res. 71, 89-102 (1987).
-
(1987)
Prog. Brain Res.
, vol.71
, pp. 89-102
-
-
Kocsis, J.D.1
Waxman, S.G.2
-
50
-
-
0033955244
-
Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states
-
Coward, K. et al. Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states. Pain 85, 41-50 (2000).
-
(2000)
Pain
, vol.85
, pp. 41-50
-
-
Coward, K.1
-
51
-
-
0016056183
-
Remyelination in relation to clinical lesions of the central nervous system
-
McDonald, W. I. Remyelination in relation to clinical lesions of the central nervous system. Br. Med. Bull. 30, 186-189 (1974).
-
(1974)
Br. Med. Bull.
, vol.30
, pp. 186-189
-
-
McDonald, W.I.1
-
52
-
-
0032576636
-
Demyelinating diseases: New pathological insights, new therapeutic targets
-
Waxman, S. G. Demyelinating diseases: new pathological insights, new therapeutic targets. N. Engl. J. Med. 338, 323-325 (1998).
-
(1998)
N. Engl. J. Med.
, vol.338
, pp. 323-325
-
-
Waxman, S.G.1
-
53
-
-
0032576752
-
Axonal transection in the lesions of multiple sclerosis
-
Trapp, B. D. et al. Axonal transection in the lesions of multiple sclerosis. W. Engl. J. Med. 338, 278-285 (1998).
-
(1998)
W. Engl. J. Med.
, vol.338
, pp. 278-285
-
-
Trapp, B.D.1
-
54
-
-
0031002545
-
Axonal damage in acute multiple sclerosis lesions
-
Ferguson, B., Matyszak, M. K., Esiri, M. M. & Perry, V. H. Axonal damage in acute multiple sclerosis lesions. Brain 120, 393-399 (1997).
-
(1997)
Brain
, vol.120
, pp. 393-399
-
-
Ferguson, B.1
Matyszak, M.K.2
Esiri, M.M.3
Perry, V.H.4
-
55
-
-
0031048695
-
Imaging of axonal damage in multiple sclerosis: Spatial distribution of magnetic resonance imaging lesions
-
Narayan, S. et al. Imaging of axonal damage in multiple sclerosis: spatial distribution of magnetic resonance imaging lesions. Ann. Neurol. 41, 385-391 (1997).
-
(1997)
Ann. Neurol.
, vol.41
, pp. 385-391
-
-
Narayan, S.1
-
56
-
-
0026703307
-
The pathological evolution of multiple sclerosis
-
McDonald, W. I., Miller, D. H. & Barnes, D. The pathological evolution of multiple sclerosis. Neuropathol. Appl. Neurobiol. 18, 319-334 (1992).
-
(1992)
Neuropathol. Appl. Neurobiol.
, vol.18
, pp. 319-334
-
-
McDonald, W.I.1
Miller, D.H.2
Barnes, D.3
-
57
-
-
0029565567
-
Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss
-
Davie, C. A. et al. Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss. Brain 118, 1583-1592 (1995). References 53-57 describe axonal degeneration and its clinical consequences in MS.
-
(1995)
Brain
, vol.118
, pp. 1583-1592
-
-
Davie, C.A.1
-
58
-
-
0017745560
-
Conduction in myelinated, unmyelinated, and demyelinated fibers
-
Waxman, S. G. Conduction in myelinated, unmyelinated, and demyelinated fibers. Arch. Neurol. 34, 585-590 (1977).
-
(1977)
Arch. Neurol.
, vol.34
, pp. 585-590
-
-
Waxman, S.G.1
-
59
-
-
0017342059
-
The density of sodium channels in mammalan myelinated nerve fibers and the nature of the axonal membrane under the myelin sheath
-
Ritchie, J. M. & Rogart, R. B. The density of sodium channels in mammalan myelinated nerve fibers and the nature of the axonal membrane under the myelin sheath. Proc. Natl Acad. Sci. USA 74, 211-215 (1977).
-
(1977)
Proc. Natl Acad. Sci. USA
, vol.74
, pp. 211-215
-
-
Ritchie, J.M.1
Rogart, R.B.2
-
60
-
-
0017902740
-
The internodal axon membrane: Electrical excitability and continuous conduction in segmental demyelination
-
Bostock, H. & Sears, T. A. The internodal axon membrane: electrical excitability and continuous conduction in segmental demyelination. J. Physiol. (Lond.) 280, 273-301 (1978).
-
(1978)
J. Physiol. (Lond.)
, vol.280
, pp. 273-301
-
-
Bostock, H.1
Sears, T.A.2
-
61
-
-
0019160539
-
Reorganization of the axonal membrane of demyelinated nerve fibers: Morphological evidence
-
Foster, R. E., Whalen, C. C. & Waxman, S. G. Reorganization of the axonal membrane of demyelinated nerve fibers: morphological evidence. Science 210, 661-663 (1980).
-
(1980)
Science
, vol.210
, pp. 661-663
-
-
Foster, R.E.1
Whalen, C.C.2
Waxman, S.G.3
-
62
-
-
0025782767
-
Increased numbers of sodium channels form along demyelinated axons
-
England, J. D., Gamboni, F. & Levinson, S. R. Increased numbers of sodium channels form along demyelinated axons. Brain Res. 548, 334-337 (1991).
-
(1991)
Brain Res.
, vol.548
, pp. 334-337
-
-
England, J.D.1
Gamboni, F.2
Levinson, S.R.3
-
63
-
-
0030767405
-
Conduction in segmentally demyelinated mammalian central axons
-
Felts, P.A., Baker, T.A. & Smith, K.J. Conduction in segmentally demyelinated mammalian central axons. J. Neurosci. 17, 7267-7277 (1997). References 60-63 show the acquisition of higher-than-normal density of sodium channels along chronically demyelinated axons, a form of molecular plasticity that can restore action potential conduction.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7267-7277
-
-
Felts, P.A.1
Baker, T.A.2
Smith, K.J.3
-
65
-
-
0035034213
-
Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon
-
Boiko, T. et al. Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon. Neuron 30, 91-104 (2001).
-
(2001)
Neuron
, vol.30
, pp. 91-104
-
-
Boiko, T.1
-
66
-
-
0033528774
-
Abnormal expression of SNS/PN3 sodium channel in cerebellar Purkinje cells following loss of myelin in the taiep rat
-
Black, J. A. et al. Abnormal expression of SNS/PN3 sodium channel in cerebellar Purkinje cells following loss of myelin in the taiep rat. Neuroreport 10, 913-918 (1999).
-
(1999)
Neuroreport
, vol.10
, pp. 913-918
-
-
Black, J.A.1
-
67
-
-
0026470050
-
The taiep rat: A myelin mutant with an associated oligodendrocyte microtubular defect
-
Duncan, I. D., Lunn, K. F., Holmgren, B., Urba-Holmgren, R. & Brignolo-Holmes, L The taiep rat: a myelin mutant with an associated oligodendrocyte microtubular defect. J. Neurocytol. 21, 870-884 (1992).
-
(1992)
J. Neurocytol.
, vol.21
, pp. 870-884
-
-
Duncan, I.D.1
Lunn, K.F.2
Holmgren, B.3
Urba-Holmgren, R.4
Brignolo-Holmes, L.5
-
68
-
-
0034633772
-
Sensory neuron specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis
-
Black, J. A. et al. Sensory neuron specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis. Proc. Natl Acad. Sci. USA 97, 11598-11602 (2000). Demonstration of a channelopathy in an animal model of MS and in human MS.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 11598-11602
-
-
Black, J.A.1
-
69
-
-
0025362249
-
Induction of chronic relapsing experimental allergic encephalomyelitis in biozzi mice
-
Baker, D. et al. Induction of chronic relapsing experimental allergic encephalomyelitis in biozzi mice. J. Neuroimmunol. 28, 261-270 (1990).
-
(1990)
J. Neuroimmunol.
, vol.28
, pp. 261-270
-
-
Baker, D.1
-
70
-
-
0034594905
-
Cannabinoids control spasticity and tremor in a multiple sclerosis model
-
Baker, D. et al. Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 404, 84-87 (2000).
-
(2000)
Nature
, vol.404
, pp. 84-87
-
-
Baker, D.1
-
72
-
-
0027414377
-
Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia
-
Elliott, A. A. & Elliott, J. R. Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia. J. Physiol. (Lond.) 463, 39-56 (1993).
-
(1993)
J. Physiol. (Lond.)
, vol.463
, pp. 39-56
-
-
Elliott, A.A.1
Elliott, J.R.2
-
73
-
-
0030832830
-
Insertion of an SNS-specifc tetrapeptide in the S3-S4 linker of D4 accelerates recovery from inactivation of skeletal muscle voltage-gated Na channel μ1 in HEK293 cells
-
Dib-Hajj, S. D., Ishikawa, I., Cummins, T. R. & Waxman, S. G. Insertion of an SNS-specifc tetrapeptide in the S3-S4 linker of D4 accelerates recovery from inactivation of skeletal muscle voltage-gated Na channel μ1 in HEK293 cells. FEBS Lett. 416, 11-14 (1997).
-
(1997)
FEBS Lett.
, vol.416
, pp. 11-14
-
-
Dib-Hajj, S.D.1
Ishikawa, I.2
Cummins, T.R.3
Waxman, S.G.4
-
74
-
-
0018910555
-
Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices
-
Llinas, R. & Sugimori, M. Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices. J. Physiol. (Lond.) 305, 171-195 (1980).
-
(1980)
J. Physiol. (Lond.)
, vol.305
, pp. 171-195
-
-
Llinas, R.1
Sugimori, M.2
-
75
-
-
0028001497
-
Initiation and spread of sodium action potentials in cerebellar purkinje cells
-
Stuart, G. & Hausser, M. Initiation and spread of sodium action potentials in cerebellar purkinje cells. Neuron 13, 703-712 (1994).
-
(1994)
Neuron
, vol.13
, pp. 703-712
-
-
Stuart, G.1
Hausser, M.2
-
76
-
-
0031010957
-
Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons
-
Raman, I. M. & Bean, B. P. Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. J. Neurosci. 17, 4517-4526 (1997). References 74-76 illustrate the presence and functional roles of multiple sodium currents in Purkinje neurons.
-
(1997)
J. Neurosci.
, vol.17
, pp. 4517-4526
-
-
Raman, I.M.1
Bean, B.P.2
-
77
-
-
0030834501
-
Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn81 mutant mice
-
Raman, I. M., Sprunger, L. K., Meisler, M. H. & Bean, B. P. Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn81 mutant mice. Neuron 19, 881-891 (1997).
-
(1997)
Neuron
, vol.19
, pp. 881-891
-
-
Raman, I.M.1
Sprunger, L.K.2
Meisler, M.H.3
Bean, B.P.4
-
78
-
-
0029789472
-
A missense mutation in the sodium channel Scn8a is responsible for cerebellar ataxia in the mouse mutant jolting
-
Kohrman, D. C., Smith, M. R., Goldin, A. L., Harris, J. & Meisler, M. H. A missense mutation in the sodium channel Scn8a is responsible for cerebellar ataxia in the mouse mutant jolting. J. Neurosci. 16, 5993-5999 (1995). References 76 and 77 show that sodium channel mutations can perturb cerebellar function.
-
(1995)
J. Neurosci.
, vol.16
, pp. 5993-5999
-
-
Kohrman, D.C.1
Smith, M.R.2
Goldin, A.L.3
Harris, J.4
Meisler, M.H.5
-
79
-
-
0033363999
-
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
-
Akopian, A. N. et al. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nature Neurosci. 2, 541-548 (1999).
-
(1999)
Nature Neurosci.
, vol.2
, pp. 541-548
-
-
Akopian, A.N.1
-
80
-
-
0026612746
-
2+ currents elicited by action potential waveforms in acutely isolated adult rat dorsal root ganglion neurons
-
2+ currents elicited by action potential waveforms in acutely isolated adult rat dorsal root ganglion neurons. J. Neurosci. 12, 1789-1801 (1992).
-
(1992)
J. Neurosci.
, vol.12
, pp. 1789-1801
-
-
Scroggs, R.S.1
Fox, A.P.2
-
83
-
-
0034987047
-
Distribution of a calcium channel submit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis
-
Komek, B. et al. Distribution of a calcium channel submit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain 124, 1114-1124 (2000).
-
(2000)
Brain
, vol.124
, pp. 1114-1124
-
-
Komek, B.1
-
84
-
-
0032958131
-
Changes in expression of voltage-gated potassium channels in dorsal root ganglion neurons following axotomy
-
Ishikawa, K., Tanaka, M., Black, J. A. & Waxman, S. G. Changes in expression of voltage-gated potassium channels in dorsal root ganglion neurons following axotomy. Muscle Nerve 22, 502-507 (1999).
-
(1999)
Muscle Nerve
, vol.22
, pp. 502-507
-
-
Ishikawa, K.1
Tanaka, M.2
Black, J.A.3
Waxman, S.G.4
-
85
-
-
0032783674
-
Reduction in potassium currents in identified cutaneous afferent dorsal root ganglion neurons after axotomy
-
Everill, B. & Kocsis, J. D. Reduction in potassium currents in identified cutaneous afferent dorsal root ganglion neurons after axotomy. J. Neurophysiol. 82, 700-708 (1999).
-
(1999)
J. Neurophysiol.
, vol.82
, pp. 700-708
-
-
Everill, B.1
Kocsis, J.D.2
-
86
-
-
0034117038
-
Voltage-gated calcium currents in axotomized adult rat cutaneous afferent neurons
-
Baccei, M. L. & Kocsis, J. D. Voltage-gated calcium currents in axotomized adult rat cutaneous afferent neurons. J. Neurophysiol. 83, 2227-2238 (2000).
-
(2000)
J. Neurophysiol.
, vol.83
, pp. 2227-2238
-
-
Baccei, M.L.1
Kocsis, J.D.2
-
87
-
-
0029658050
-
A-receptor-mediated conductance and action potential waveform in cutaneous and muscle afferent neurons of the adult rat: Differential expression and response to nerve injury
-
A-receptor-mediated conductance and action potential waveform in cutaneous and muscle afferent neurons of the adult rat: differential expression and response to nerve injury. J. Neurophysiol. 76, 2383-2392 (1996).
-
(1996)
J. Neurophysiol.
, vol.76
, pp. 2383-2392
-
-
Oyelese, A.A.1
Kocsis, J.D.2
-
89
-
-
0031410780
-
Regulation of expression of the sensory neuron-specific sodium channel SNS in inflammatory and neuropathic pain
-
Okuse, K. et al. Regulation of expression of the sensory neuron-specific sodium channel SNS in inflammatory and neuropathic pain. Mol. Cell. Neurosci. 10, 196-207 (1997).
-
(1997)
Mol. Cell. Neurosci.
, vol.10
, pp. 196-207
-
-
Okuse, K.1
-
90
-
-
0346870555
-
Sodium channel type III is unregulated in three mechanistically different models of experimental allodynia
-
Chaplan, S. R., Calcutt, N. & Higuera, E. S. Sodium channel type III is unregulated in three mechanistically different models of experimental allodynia. J. Pain 2 (Suppl. 2), 21 (2001).
-
(2001)
J. Pain
, vol.2
, Issue.2 SUPPL.
, pp. 21
-
-
Chaplan, S.R.1
Calcutt, N.2
Higuera, E.S.3
-
91
-
-
0031054294
-
Increase in mRNAs encoding neonatal II and III sodium channel α-isoforms during kainate-induced seizures in adult rat hippocampus
-
Gastaldi, M. et al. Increase in mRNAs encoding neonatal II and III sodium channel α-isoforms during kainate-induced seizures in adult rat hippocampus. Brain Res. Mol. Brain Res. 44, 179-190 (1997).
-
(1997)
Brain Res. Mol. Brain Res.
, vol.44
, pp. 179-190
-
-
Gastaldi, M.1
-
92
-
-
0031841255
-
Sodium currents in isolated rat CA1 neurons after kindling epileptogenesis
-
Vreugdenhil, M., Faas, G. C. & Wadman, W. J. Sodium currents in isolated rat CA1 neurons after kindling epileptogenesis. Neuroscience 86, 99-107 (1998).
-
(1998)
Neuroscience
, vol.86
, pp. 99-107
-
-
Vreugdenhil, M.1
Faas, G.C.2
Wadman, W.J.3
-
93
-
-
0026659651
-
Silencing the type II sodium channel gene: A model for neural-specific gene regulation
-
Kraner, S. D., Chong, J. A., Tsay. H.-J. & Mandel, G. Silencing the type II sodium channel gene: a model for neural-specific gene regulation. Neuron 9, 37-44 (1992).
-
(1992)
Neuron
, vol.9
, pp. 37-44
-
-
Kraner, S.D.1
Chong, J.A.2
Tsay, H.-J.3
Mandel, G.4
-
95
-
-
0028947293
-
A single pulse of nerve growth factor triggers tang-term neuronal excitability through sodium channel gene induction
-
Toledo-Aral, J. J., Brehm, P., Halegoua, S. & Mendel, G. A single pulse of nerve growth factor triggers tang-term neuronal excitability through sodium channel gene induction. Neuron 14, 607-611 (1995).
-
(1995)
Neuron
, vol.14
, pp. 607-611
-
-
Toledo-Aral, J.J.1
Brehm, P.2
Halegoua, S.3
Mendel, G.4
-
96
-
-
0032550133
-
+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model
-
+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model. Neuroreport 9, 967-972 (1998).
-
(1998)
Neuroreport
, vol.9
, pp. 967-972
-
-
Tanaka, M.1
|