Using substrate analogues to probe the kinetic mechanism and active site of Escherichia coli MenD

Biochemistry

Volumn 50, Issue 40, 2011, Pages 8712-8721

  Fang, Maohai ^a   MacOva, Andrea ^a   Hanson, Kimberly L ^a   Kos, Jillian ^a   Palmer, David R J ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CARBOLIGATION; KETOGLUTARATE; KINETIC ASSAY; KINETIC EXPERIMENT; KINETIC MECHANISM; NATURAL SUBSTRATES; SUBSTRATE CONCENTRATIONS; SYNTHETIC SUBSTRATES;

BIOCHEMISTRY; ENZYMES; ESCHERICHIA COLI; KINETICS;

SUBSTRATES;

2 OXOGLUTARIC ACID; CHORISMIC ACID; MEND PROTEIN; METHYL SUCCINYLPHOSPHONATE; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME KINETICS; ESCHERICHIA COLI; MUTATION; NONHUMAN; PRIORITY JOURNAL; SYNTHESIS;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CHORISMIC ACID; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PYRUVATE OXIDASE; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI;

EID: 80053606510     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201202n     Document Type: Article

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