Local mild hypothermia with thrombolysis for acute ischemic stroke within a 6-h window

Clinical Neurology and Neurosurgery

Volumn 113, Issue 9, 2011, Pages 768-773

  Bi, Min ^a,b   Ma, Qilin ^a   Zhang, Shiyang ^a   Li, Jianpeng ^a   Zhang, Yidan ^a   Lin, Longting ^b   Tong, Suijun ^a   Wang, Desheng ^b  

^a THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Acute ischemic stroke; Local mild hypothermia; Magnetic resonance imaging; PWI DWI mismatch; Thrombolysis; Tissue plasminogen activator

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; CLOPIDOGREL; THROMBOCYTE ANTIBODY;

ACUTE ISCHEMIC STROKE; ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; BRAIN ISCHEMIA; CHINESE MEDICINE; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; FEMALE; HUMAN; HYPOTHERMIA; MAJOR CLINICAL STUDY; MALE; MORTALITY; PERFUSION WEIGHTED IMAGING; PROTEIN AGGREGATION; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SALVIA MILTIORRHIZA; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME;

AGED; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HUMANS; HYPOTHERMIA, INDUCED; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE ANGIOGRAPHY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PLATELET AGGREGATION INHIBITORS; STROKE; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME;

EID: 80053602560     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2011.08.010     Document Type: Article

References (43)

1. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rtPA Stroke Study Group N Engl J Med 333 December (24) 1995 1581 1587
2. W.M. Clark, S. Wissman, G.W. Albers, J.H. Jhamandas, K.P. Madden, and S. Hamilton Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke JAMA 282 December (21) 1999 2019 2026
3. W. Hacke, M. Kaste, C. Fieschi, D. Toni, E. Lesaffre, and R. von Kummer Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS) JAMA 274 October (13) 1995 1017 1025
4. W. Hacke, M. Kaste, C. Fieschi, R. von Kummer, A. Davalos, and D. Meier Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators Lancet 352 October (9136) 1998 1245 1251 (Pubitemid 28470336)
5. W. Hacke, M. Kaste, E. Bluhmki, M. Brozman, A. Davalos, and D. Guidetti Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke N Engl J Med 359 September (13) 2008 1317 1329
6. J.O. Heidenreich, D. Hsu, G. Wang, J.A. Jesberger, R.W. Tarr, and O.O. Zaidat Magnetic resonance imaging results can affect therapy decisions in hyperacute stroke care Acta Radiol 49 June (5) 2008 550 557
7. N. Hjort, K. Butcher, S.M. Davis, C.S. Kidwell, W.J. Koroshetz, and J. Rother Magnetic resonance imaging criteria for thrombolysis in acute cerebral infarct Stroke 36 February (2) 2005 388 397 (Pubitemid 40170827)
8. J. Rother, P.D. Schellinger, A. Gass, M. Siebler, A. Villringer, and J.B. Fiebach Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours Stroke 33 October (10) 2002 2438 2445
9. G. Toth, and G.W. Albers Use of MRI to estimate the therapeutic window in acute stroke: is perfusion-weighted imaging/diffusion-weighted imaging mismatch an EPITHET for salvageable ischemic brain tissue? Stroke 40 January (1) 2009 333 335
10. C.S. Kidwell, J.R. Alger, and J.L. Saver Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging Stroke 34 November (11) 2003 2729 2735 (Pubitemid 37392775)
11. M. Ribo, C.A. Molina, A. Rovira, M. Quintana, P. Delgado, and J. Montaner Safety and efficacy of intravenous tissue plasminogen activator stroke treatment in the 3- to 6-hour window using multimodal transcranial Doppler/MRI selection protocol Stroke 36 March (3) 2005 602 606 (Pubitemid 40344163)
12. S. Nagel, M. Papadakis, L. Hoyte, and A.M. Buchan Therapeutic hypothermia in experimental models of focal and global cerebral ischemia and intracerebral hemorrhage Expert Rev Neurother 8 August (8) 2008 1255 1268
13. M.D. Hammer, and D.W. Krieger Hypothermia for acute ischemic stroke: not just another neuroprotectant Neurologist 9 November (6) 2003 280 289 (Pubitemid 37484847)
14. R.A. Jonas Neurological protection during cardiopulmonary bypass/deep hypothermia Pediatr Cardiol 19 July-August (4) 1998 321 330 (Pubitemid 28290047)
15. S.A. Bernard, T.W. Gray, M.D. Buist, B.M. Jones, W. Silvester, and G. Gutteridge Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia N Engl J Med 346 February (8) 2002 557 563 (Pubitemid 34438816)
16. J.P. Nolan, P.T. Morley, T.L. Vanden Hoek, R.W. Hickey, W.G. Kloeck, and J. Billi Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation Circulation 108 July (1) 2003 118 121 (Pubitemid 36859031)
17. V.E. O'Collins, M.R. Macleod, G.A. Donnan, L.L. Horky, B.H. van der Worp, and D.W. Howells 1,026 experimental treatments in acute stroke Ann Neurol 59 March (3) 2006 467 477 (Pubitemid 43358067)
18. H. Yanamoto, I. Nagata, Y. Niitsu, Z. Zhang, J.H. Xue, and N. Sakai Prolonged mild hypothermia therapy protects the brain against permanent focal ischemia Stroke 32 January (1) 2001 232 239 (Pubitemid 32065700)
19. S. Schwab, S. Schwarz, M. Spranger, E. Keller, M. Bertram, and W. Hacke Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction Stroke 29 12 Dec 1998 2461 2466 (Pubitemid 28543990)
20. H.P. Adams Jr., G. del Zoppo, M.J. Alberts, D.L. Bhatt, L. Brass, and A. Furlan Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists Circulation 115 May (20) 2007 e478 e534
21. M.D. Ginsberg, and R. Busto Combating hyperthermia in acute stroke: a significant clinical concern Stroke 29 February (2) 1998 529 534 (Pubitemid 28086703)
22. S. Martin-Schild, H. Hallevi, H. Shaltoni, A.D. Barreto, N.R. Gonzales, and J. Aronowski Combined neuroprotective modalities coupled with thrombolysis in acute ischemic stroke: a pilot study of caffeinol and mild hypothermia J Stroke Cerebrovasc Dis 18 March-April (2) 2009 86 96
23. Y. Ding, J. Li, X. Luan, Q. Lai, J.P. McAllister 2nd., and J.W. Phillis Local saline infusion into ischemic territory induces regional brain cooling and neuroprotection in rats with transient middle cerebral artery occlusion Neurosurgery 54 April (4) 2004 956 964 discussion 964-955
24. D. Wang, W. Liu, and H. Feng The effect of focal mild hypothermia on the temperature gradient in brain Natl Med J China 14 81 2001 849 851
25. D. Wang, Y. Tang, and W. Wang Selective and mild hypothermia combined with urokinase for acute cerebral infarctions J Apoplexy Nerv Dis 23 3 2006 287 289
26. R. Zhao, Y. Zhang, and Z. Li The Study of focal mild hypothermia in on prolonging the theraputic time window after cerebral infarct in rats Chin J Neurol 38 6 2005
27. T. Neumann-Haefelin, H.J. Wittsack, F. Wenserski, M. Siebler, R.J. Seitz, and U. Modder Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke Stroke 30 August (8) 1999 1591 1597 (Pubitemid 29379608)
28. T. Brott, H.P. Adams Jr., C.P. Olinger, J.R. Marler, W.G. Barsan, and J. Biller Measurements of acute cerebral infarction: a clinical examination scale Stroke 20 July (7) 1989 864 870 (Pubitemid 19188240)
29. J.C. van Swieten, P.J. Koudstaal, M.C. Visser, H.J. Schouten, and J. van Gijn Interobserver agreement for the assessment of handicap in stroke patients Stroke 19 May (5) 1988 604 607
30. F.I. Mahoney, and D.W. Barthel Functional evaluation: the Barthel index Md State Med J February (14) 1965 61 65
31. W.M. Clark, G.W. Albers, K.P. Madden, and S. Hamilton The rtPA (alteplase) 0- to 6-hour acute stroke trial, part A (A0276g): results of a double-blind, placebo-controlled, multicenter study. Thromblytic therapy in acute ischemic stroke study investigators Stroke 31 4 Apr 2000 811 816 (Pubitemid 30198420)
32. A. Arboix Thrombolytic treatment in acute cerebral infarction Neurol India 55 January-March (1) 2007 8 9
33. L. Liu, X. Tang, M. Koike, and M. Yenari Mild Hypothermia reduces hemorrhage and blood-brain barrier (BBB) disruption following tissue plasminogen activator treatment in experimental stroke Neurology 66 6 2006 A242 A243
34. T. Kunimatsu, A. Yamashita, H. Kitahama, T. Misaki, and T. Yamamoto Measurement of cerebral reactive hyperemia at the initial post-ischemia reperfusion stage under normothermia and moderate hypothermia in rats J Oral Sci 51 December (4) 2009 615 621
35. L. Xu, M.A. Yenari, G.K. Steinberg, and R.G. Giffard Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade J Cereb Blood Flow Metab 22 January (1) 2002 21 28 (Pubitemid 34038379)
36. D.W. Krieger, and M.A. Yenari Therapeutic hypothermia for acute ischemic stroke: what do laboratory studies teach us? Stroke 35 June (6) 2004 1482 1489 (Pubitemid 38697480)
37. R. Kollmar, N. Henninger, J. Bardutzky, P.D. Schellinger, W.R. Schabitz, and S. Schwab Combination therapy of moderate hypothermia and thrombolysis in experimental thromboembolic stroke - an MRI study Exp Neurol 190 November (1) 2004 204 212 (Pubitemid 39335719)
38. P. Meden, K. Overgaard, H. Pedersen, and G. Boysen Effect of hypothermia and delayed thrombolysis in a rat embolic stroke model Acta Neurol Scand 90 August (2) 1994 91 98 (Pubitemid 24261203)
39. M.A. Yenari, J.T. Palmer, P.M. Bracci, and G.K. Steinberg Thrombolysis with tissue plasminogen activator (tPA) is temperature dependent Thromb Res 77 March (5) 1995 475 481
40. A.S. Wolberg, Z.H. Meng, D.M. Monroe 3rd., and M. Hoffman A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function J Trauma 56 June (6) 2004 1221 1228 (Pubitemid 38901832)
41. W. Hacke, G. Albers, Y. Al-Rawi, J. Bogousslavsky, A. Davalos, and M. Eliasziw The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase Stroke 36 January (1) 2005 66 73 (Pubitemid 40054177)
42. M.P. Marks, J.M. Olivot, S. Kemp, M.G. Lansberg, R. Bammer, and L.R. Wechsler Patients with acute stroke treated with intravenous tPA 3-6 hours after stroke onset: correlations between MR angiography findings and perfusion- and diffusion-weighted imaging in the DEFUSE study Radiology 249 November (2) 2008 614 623
43. J.M. Olivot, M. Mlynash, V.N. Thijs, S. Kemp, M.G. Lansberg, and L. Wechsler Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE) Stroke 39 August (8) 2008 2257 2263