The study of focal mild hypothermia on prolonging the therapeutic time window after cerebral infarct in rats

Chinese Journal of Neurology

Volumn 38, Issue 6, 2005, Pages 377-380

  Zhao, Rui Bo ^a   Zhang, Yu Hua ^b   Li, Zong Min ^b   Wang, De Sheng ^b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

Apoptosis; Brain ischemia; Hypothermia, induced; NF kappa B

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTERY OCCLUSION; ARTICLE; BRAIN ARTERY; BRAIN INFARCTION; BRAIN NERVE CELL; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; HYPOTHERMIA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; REPERFUSION;

EID: 24944579954     PISSN: 10067876     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Longa EZ, Weinstein PR, Carlson S, et al. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke, 1989, 20: 84-91.
2. Carolina M, Mailer BS, Kristine VB, et al. Optimal depth and duration of mild hypothermia in a focal model of transient cerebral ischemia. Stroke, 1998, 29: 2171-2180.
3. Gabriel C, Justicia C, Camins A, et al. Activation of nuclear factor-kappa B in the rat brain after transient focal ischemia. Brain Res Mol Brain Res, 1999, 65:61-69.
4. Schneider A, Martin-Villalba A, Weih F, et al. NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat Med, 1999, 5:554-559.
5. Carroll JE, Howard EF, Hess DC, et al. Nuclear factor-kappa B activation during cerebral reperfusion: effect of attenuation with N-acetylcysteine treatment. Brain Res Mol Brain Res, 1998, 56:186-191.
6. Seegers H, Grillon E, Trioullier Y, et al. Nuclear factor-kappa B activation in permanent intraluminal focal cerebral ischemia in the rat. Neurosci Lett, 2000, 288:241-245.
7. Clemens JA, Stephenson DT, Dixon EP, et al. Global cerebral ischemia activates nuclear factor-kappa B prior to evidence of DNA fragmentation. Brain Res Mol Brain Res, 1997, 48:187-196.
8. Clemens JA, Stephenson DT, Yin T, et al. Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-kappa B in rats. Stroke, 1998, 29:677-682.
9. Dixon EP, Stephenson DT, Clemens JA, et al. Bcl-Xshort is elevated following severe global ischemia in rat brains. Brain Res, 1997, 776:222-229.
10. Hu WH, Johnson H, Shu HB. Activation of NF-kappaB by FADD, Casper, and caspase-8. J Biol Chem, 2000, 275:10838-10844.
11. Han HS, Karabiyikoglu M, Kelly S, et al. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. J Cereb Blood Flow Metab, 2003, 23:589-598.