Combating hyperthermia in acute stroke: A significant clinical concern

Stroke

Volumn 29, Issue 2, 1998, Pages 529-534

  Ginsberg, Myron D ^a   Busto, Raul ^b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Fever; Hypothermia; Ischemia; Neuroprotection

Indexed keywords

NEUROTRANSMITTER; OXYGEN RADICAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN METABOLISM; BRAIN TEMPERATURE; CORE TEMPERATURE; CYTOSKELETON; DEPOLARIZATION; ENERGY METABOLISM; HYPERTHERMIA; HYPOTHERMIA; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; REVIEW; SECOND MESSENGER; STROKE;

EID: 0031885950     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.29.2.529     Document Type: Review

References (60)

1. Ginsberg MD, Stemau LL, Globus MY-T, Dietrich WD, Busto R. Therapeutic modulation of brain temperature: relevance to ischemic brain injury. Cerebrovasc Brain Metab Rev. 1992;4:189-225.
2. Maher J, Hachinski V. Hypothermia as a potential treatment for cerebral ischemia. Cerebrovasc Brain Metab Rev. 1993;5:277-300.
3. Ginsberg MD. The concept of the therapeutic window: a synthesis of critical issues. In: Moskowitz MA, Caplan LR, eds. Cerebrovascular Diseases: Nineteenth Princeton Stroke Conference. Boston, Mass: Butterworth-Heinemann; 1995:331-351.
4. Dietrich WD, Busto R, Globus MY-T, Ginsberg MD. Brain damage and temperature: cellular and molecular mechanisms. In: Siesjö BK, Wieloch T, eds. Cellular and Molecular Mechanisms of Ischemic Brain Damage. Philadelphia, Pa: Lippincott-Raven; 1996:177-197. Advances in Neurology series.
5. Barone F, Feuerstein GZ, White RF. Brain cooling during transient focal ischemia provides complete neuroprotection. Neurosci Biobehav Rev. 1996; 21:31-44.
6. Busto R, Ginsberg MD. The influence of altered brain temperature in cerebral ischemia. In: Ginsberg MD, Bougousslavsky J, eds. Cerebrovascular Disease: Pathophysiology, Diagnosis and Treatment. Cambridge, Mass: Blackwell Scientific Publications, Inc. In press.
7. Pulsinelli WA, Brierley JB. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke. 1979;10:267-272.
8. Busto R, Dietrich WD, Globus MY-T, Valdés I, Scheinberg P, Ginsberg MD. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab. 1987;7:729-738.
9. Dietrich WD, Busto R, Valdés I, Loor Y. Effects of normothermic versus mild hyperthermic forebrain ischemia in rats. Stroke. 1990;21:1318-1325.
10. Minamisawa H, Smith M-L, Siesjö BK. The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 minutes of forebrain ischemia. Ann Neurol. 1990;28:26-33.
11. 1 neurons in gerbils. J Cereb Blood Flow Metab. 1990;10:550-556.
12. Churn SB, Taft WC, Billingsley MS, Blair RE, DeLorenzo RJ. Temperature modulation of ischemic neuronal death and inhibition of calcium/ calmodulin-dependent protein kinase II in gerbils. Stroke. 1990;21: 1715-1721.
13. Wass CT, Lanier WL, Hofer RE, Scheithauer BW, Andrews AG. Temperature changes of ≥1°C alter functional neurologic outcome and histopathology in a canine model of complete cerebral ischemia. Anesthesiology. 1995;83:325-335.
14. Coimbra C, Drake M, Boris-Möller F, Wieloch T. Long-lasting neuroprotective effect of postischemic hypothermia and treatment with an anti-inflammatory/antipyretic drug: evidence for chronic encephalopathic processes following ischemia. Stroke. 1996;27:1578-1585.
15. Coimbra C, Boris-Möller F, Drake M, Wieloch T. Diminished neuronal damage in the rat brain by late treatment with the antipyretic drug dipyrone or cooling following cerebral ischemia. Acta Neuropathol (Berl). 1996;92: 447-453.
16. Morikawa E, Ginsberg MD, Dietrich WD, Duncan RC, Kraydieh S, Globus MY-T, Busto R. The significance of brain temperature in focal cerebral ischemia: histopathological consequences of middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab. 1992;12:380-389.
17. Chen H, Chopp M, Welch KMA. Effect of mild hyperthermia on the ischemic infarct volume after middle cerebral artery occlusion in the rat. Neurology. 1991;41:1133-1135.
18. Memezawa H, Zhao Q, Smith M-L, Siesjö BK. Hyperthermia nullifies the ameliorating effect of dizocilpine maleate (MK-801) in focal cerebral ischemia. Brain Res. 1995;670:48-52.
19. Ginsberg MD. Neuroprotection in brain ischemia: an update, parts I and II. Neuroscientist. 1995;1:95-103, 164-175.
20. Meden P, Overgaard K, Pedersen H, Boysen G. The influence of body temperature on infarct volume and thrombolytic therapy in a rat embolic stroke model. Brain Res. 1994;647:131-138.
21. NINDS rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
22. NINDS rt-PA Stroke Study Group. A systems approach to immediate evaluation and management of hyperacute stroke. Stroke. 1997;28: 1530-1540.
23. Sternau LL, Globus MY-T, Dietrich WD, Martinez E, Busto R, Ginsberg MD. Ischemia-induced neurotransmitter release: effects of mild intraischemic hyperthermia. In: Globus MY-T, Dietrich WD, eds. The Role of Neurotransmitters in Brain Injury. New York, NY: Plenum Press; 1992: 33-38.
24. Globus MY-T, Ginsberg MD, Busto R. Excitotoxic index: a biochemical marker of selective vulnerability. Neurosci Lett. 1991;127:39-42.
25. Takagi K, Ginsberg MD, Globus MY-T, Martinez E, Busto R. Effect of hyperthermia on glutamate release in ischemic penumbra after middle cerebral artery occlusion in rats occlusion in rats. Am J Physiol (Heart Circ Physiol 35). 1994; 266:H1770-H1776.
26. Globus MY-T, Busto R, Lin B, Schnippenng, Ginsberg MD. Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation. J Neurochem. 1995; 65:1250-1256.
27. Kil HY, Zhang J, Piantadosi CA. Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats. J Cereb Blood Flow Metab. 1996;16:100-106.
28. Dietrich WD, Busto R, Halley M, Valdés I. The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia. J Neuropathol Exp Neurol. 1990;49:486-497.
29. Dietrich WD, Halley M, Valdés I, Busto R. Interrelationships between increased vascular permeability and acute neuronal damage following temperature-controlled brain ischemia in rats. Acta Neuropathol (Berl). 1991; 81:615-625.
30. Back T, Kohno K, Hossniann K-A. Cortical negative DC deflections following middle cerebral artery occlusion and KCl-induced spreading depression: effect on blood flow, tissue oxygenation, and electroencephalogram. J Cereb Blood Flow Metab. 1994;14:12-19.
31. Back T, Zhao W, Ginsberg MD. Three-dimensional image-analysis of brain glucose metabolism/blood flow uncoupling and its electrophysiological correlates in the acute ischemic penumbra following middle cerebral artery occlusion. J Cereb Blood Flow Metab. 1995;15:566-577.
32. Takeda Y, Jacewicz M, Takeda Y, Nowak TS Jr, Pulsinelli WA. DC-potential and energy metabolites in the focal ischemia. J Cereb Blood Flow Metab. 1993;13(suppl 1):S450. Abstract.
33. Back T, Ginsberg MD, Dietrich WD, Watson BD. Induction of spreading depression in the ischemic hemisphere following experimental middle cerebral artery occlusion: effect on infarct morphology. J Cereb Blood Flow Metab. 1996;16:202-213.
34. Mies G, Iijima T, Hossmann K-A. Correlation between peri-infarct DC shifts and ischemic neuronal damage in cerebral cortex of rat. Neuroreport. 1993;4:709-711.
35. Back T, Nedergaard M, Ginsberg MD. The ischemic penumbra: pathophysiology, and relevance of spreading depression-like phenomena. In: Ginsberg MD, Bougousslavsky J, eds. Cerebrovascular Disease: Pathophysiology, Diagnosis and Treatment. Cambridge. Mass: Blackwell Scientific Publications, Inc. In press.
36. Chen Q, Chopp M, Bodzin G, Chen H. Temperature modulation of cerebral depolarization during focal cerebral ischemia in rats: correlation with ischemic injury. J Cereb Blood Flow Metab. 1993;13:389-394.
37. Chopp M, Welch KMA, Tidwell CD, Knight R, Helpern JA. Effect of mild hyperthermia on recovery of metabolic function after global cerebral ischemia in cats. Stroke. 1988;19:1521-1525.
38. Ginsberg MD, Busto R, Martinez E, Globus MY-T, Valdés I, Loor JY. The effects of cerebral ischemia on energy metabolism. In: Schousboe A, Diemer NH, Kofod H, eds. Drug Research Related to Neuroactive Amino Acids: Alfred Benzon Symposium 32. Copenhagen, Denmark: Munksgaard; 1992:207-224.
39. Busto R, Globus MY-T, Neary JT, Ginsberg MD. Regional alterations of protein kinase C activity following transient cerebral ischemia: effects of intraischemic brain temperature modulation. J Neurochem. 1994;63: 1095-1103.
40. Morimoto T, Ginsberg MD, Dietrich WD, Zhao W. Hyperthermia enhances spectrin breakdown in transient focal cerebral ischemia. Brain Res. 1997;746:43-51.
41. Eguchi Y, Yamashita K, Iwamoto T, Ito H. Effects of brain temperature on calmodulin and micro tubule-associated protein 2 immunoreactivity in the gerbil hippocampus following transient forebrain ischemia. J Neurotrauma. 1997;14:109-118.
42. Kim Y, Busto R, Dietrich WD, Kraydieh S, Ginsberg MD. Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia. Stroke. 1996;27:2274-2281.
43. Baena RC, Busto R, Dietrich WD, Globus MY-T, Ginsberg MD. Hyperthermia delayed by 24 hours aggravates neuronal damage in rat hippocampus following global ischemia. Neurology. 1997;48:768-773.
44. Dietrich WD, Alonso O, Halley M, Busto R. Delayed posttraumatic brain hyperthermia worsens outcome after fluid percussion brain injury: a light and electron microscopic study in rats. Neurosurgery. 1996;38:533-541.
45. Mellergård P, Nordström C-H. Intracerebral temperature in neurosurgical patients, Neurosurgery. 1991;28:709-713.
46. Sternau L, Thompson C, Dietrich WD, Busto R, Globus MY-T, Ginsberg MD. Intracranial temperature: observations in the human brain. J Cereb Blood Flow Metab. 1991;11(suppl 2):S123. Abstract.
47. Hiyashi N, Hirayama T, Ohata M. The computed cerebral hypothermia management technique to the critical head injury patients. Adv Neurotraum Res. 1993;5:61-64.
48. Verlooy J, Heytens L, Veeckmans G, Selosse P. Intracerebral temperature monitoring in severely head injured patients. Acta Neurochir (Wien). 1995; 134:76-78.
49. Takino M, Okada Y. Hyperthermia following cardiopulmonary resuscitation. Intensive Care Med. 1991;17:419-420.
50. Smith PL, Newman SP, Ell PJ, Harrison MJ, Treasure T, Joseph P. Cerebral consequences of cardiopulmonary bypass. Lancet. 1986;1: 823-825.
51. Cook DJ, Orszulak TA, Daly RC, Buda DA. Cerebral hyperthermia during cardiopulmonary bypass in adults. J Thorac Cardiovasc Surg. 1996; 111:268-269.
52. Schwab S, Spranger M, Aschoff A, Steiner T, Hacke W. Brain temperature monitoring and modulation in patients with severe MCA infarction. Neurology. 1997;48:762-767.
53. Hindfelt B. The prognostic significance of subfebrility and fever in ischemic cerebral infarction. Acta Neurol Scand. 1976;53:72-79.
54. Castillo J, Martinez F, Leira R, Prieto JM, Lema M, Noya M. Mortality and morbidity of acute cerebral infarction related to temperature and basal analytic parameters. Cerebrovasc Dis. 1994;4:56-71.
55. Azzimondi G, Bassein L, Nonino F, Fiorani L, Vignatelli L, Re G, D'Alessandro R. Fever in acute stroke worsens prognosis: a prospective study. Stroke. 1995;26:2040-2043.
56. Reith J, Jorgensen HS, Pedersen PM, Nakayama H, Raaschou HO, Jeppesen LL, Olsen TS. Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome. Lancet. 1996;347: 422-425.
57. Macko RF, Ameriso SF, Barndt R, Clough W, Weiner JM, Fisher M. Precipitants of brain infarction: roles of preceding infection/inflammation and recent psychological stress. Stroke. 1996;27:1999-2004.
58. Marion DW, Penrod LE, Kelsey SF, Obrist WD, Kochanek PM, Palmer AM, Wisniewski SR, DeKosky ST. Treatment of traumatic brain injury with moderate hypothermia. N Engl J Med. 1997;336:540-546.
59. Clifton GL, Allen S, Barrodale P, Plenger P, Berry J, Koch S, Fletcher J, Hayes RL, Choi SC. A phase II study of moderate hypothermia in severe brain injury. J Neurotrauma. 1993;10:263-271.
60. Metz C, Holzschuh M, Bein T, Woertgen C, Frey A, Frey I, Taeger K, Brawanski A. Moderate hypothermia in patients with severe head injury: cerebral and extracerebral effects. J Neurosurg. 1996;85:533-541.