-
1
-
-
67650357912
-
Therapeutic targeting of MLL
-
Liedtke M, Cleary ML, (2009) Therapeutic targeting of MLL. Blood 113: 6061-6068.
-
(2009)
Blood
, vol.113
, pp. 6061-6068
-
-
Liedtke, M.1
Cleary, M.L.2
-
2
-
-
77956512516
-
MLL: exploring the methylome
-
Burmeister T, (2010) MLL: exploring the methylome. Blood 115: 4627-4628.
-
(2010)
Blood
, vol.115
, pp. 4627-4628
-
-
Burmeister, T.1
-
3
-
-
0026454451
-
Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
-
Tkachuk DC, Kohler S, Cleary ML, (1992) Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71: 691-700.
-
(1992)
Cell
, vol.71
, pp. 691-700
-
-
Tkachuk, D.C.1
Kohler, S.2
Cleary, M.L.3
-
4
-
-
0035839952
-
Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins
-
Ayton PM, Cleary ML, (2001) Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene 20: 5695-5707.
-
(2001)
Oncogene
, vol.20
, pp. 5695-5707
-
-
Ayton, P.M.1
Cleary, M.L.2
-
6
-
-
0027279628
-
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
-
Thirman MJ, Gill HJ, Burnett RC, Mbangkollo D, McCabe NR, et al. (1993) Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N Engl J Med 329: 909-914.
-
(1993)
N Engl J Med
, vol.329
, pp. 909-914
-
-
Thirman, M.J.1
Gill, H.J.2
Burnett, R.C.3
Mbangkollo, D.4
McCabe, N.R.5
-
7
-
-
77954367863
-
Development of five dual-color, double-fusion fluorescence in situ hybridization assays for the detection of common MLL translocation partners
-
Keefe JG, Sukov WR, Knudson RA, Nguyen LP, Williamson C, et al. (2010) Development of five dual-color, double-fusion fluorescence in situ hybridization assays for the detection of common MLL translocation partners. J Mol Diagn 12: 441-452.
-
(2010)
J Mol Diagn
, vol.12
, pp. 441-452
-
-
Keefe, J.G.1
Sukov, W.R.2
Knudson, R.A.3
Nguyen, L.P.4
Williamson, C.5
-
8
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Krivtsov AV, Armstrong SA, (2007) MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 7: 823-833.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
9
-
-
0030791974
-
Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL
-
Lavau C, Szilvassy SJ, Slany R, Cleary ML, (1997) Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. EMBO J 16: 4226-4237.
-
(1997)
EMBO J
, vol.16
, pp. 4226-4237
-
-
Lavau, C.1
Szilvassy, S.J.2
Slany, R.3
Cleary, M.L.4
-
10
-
-
0141680407
-
Dimerization of MLL fusion proteins immortalizes hematopoietic cells
-
Martin ME, Milne TA, Bloyer S, Galoian K, Shen W, et al. (2003) Dimerization of MLL fusion proteins immortalizes hematopoietic cells. Cancer Cell 4: 197-207.
-
(2003)
Cancer Cell
, vol.4
, pp. 197-207
-
-
Martin, M.E.1
Milne, T.A.2
Bloyer, S.3
Galoian, K.4
Shen, W.5
-
11
-
-
18544375333
-
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
-
Armstrong SA, Staunton JE, Silverman LB, Pieters R, den Boer ML, et al. (2002) MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat Genet 30: 41-47.
-
(2002)
Nat Genet
, vol.30
, pp. 41-47
-
-
Armstrong, S.A.1
Staunton, J.E.2
Silverman, L.B.3
Pieters, R.4
den Boer, M.L.5
-
12
-
-
68749113985
-
Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
-
Mayr C, Bartel DP, (2009) Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138: 673-684.
-
(2009)
Cell
, vol.138
, pp. 673-684
-
-
Mayr, C.1
Bartel, D.P.2
-
13
-
-
77953629046
-
Regulation of mRNA translation and stability by microRNAs
-
Fabian MR, Sonenberg N, Filipowicz W, (2010) Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 79: 351-379.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 351-379
-
-
Fabian, M.R.1
Sonenberg, N.2
Filipowicz, W.3
-
14
-
-
34547791273
-
Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
-
le Sage C, Nagel R, Egan DA, Schrier M, Mesman E, et al. (2007) Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J 26: 3699-3708.
-
(2007)
EMBO J
, vol.26
, pp. 3699-3708
-
-
le Sage, C.1
Nagel, R.2
Egan, D.A.3
Schrier, M.4
Mesman, E.5
-
15
-
-
38349118916
-
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA
-
Kedde M, Strasser MJ, Boldajipour B, Oude Vrielink JA, Slanchev K, et al. (2007) RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. Cell 131: 1273-1286.
-
(2007)
Cell
, vol.131
, pp. 1273-1286
-
-
Kedde, M.1
Strasser, M.J.2
Boldajipour, B.3
Oude Vrielink, J.A.4
Slanchev, K.5
-
16
-
-
33947431322
-
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
-
Mayr C, Hemann MT, Bartel DP, (2007) Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315: 1576-1579.
-
(2007)
Science
, vol.315
, pp. 1576-1579
-
-
Mayr, C.1
Hemann, M.T.2
Bartel, D.P.3
-
17
-
-
23944514849
-
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation
-
Bagga S, Bracht J, Hunter S, Massirer K, Holtz J, et al. (2005) Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122: 553-563.
-
(2005)
Cell
, vol.122
, pp. 553-563
-
-
Bagga, S.1
Bracht, J.2
Hunter, S.3
Massirer, K.4
Holtz, J.5
-
18
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, et al. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433: 769-773.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
-
19
-
-
33644853907
-
The colorectal microRNAome
-
Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, et al. (2006) The colorectal microRNAome. Proc Natl Acad Sci U S A 103: 3687-3692.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3687-3692
-
-
Cummins, J.M.1
He, Y.2
Leary, R.J.3
Pagliarini, R.4
Diaz Jr., L.A.5
-
20
-
-
34548316982
-
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
-
Ebert MS, Neilson JR, Sharp PA, (2007) MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 4: 721-726.
-
(2007)
Nat Methods
, vol.4
, pp. 721-726
-
-
Ebert, M.S.1
Neilson, J.R.2
Sharp, P.A.3
-
21
-
-
0037049641
-
The transcription cycle of RNA polymerase II in living cells
-
Kimura H, Sugaya K, Cook PR, (2002) The transcription cycle of RNA polymerase II in living cells. J Cell Biol 159: 777-782.
-
(2002)
J Cell Biol
, vol.159
, pp. 777-782
-
-
Kimura, H.1
Sugaya, K.2
Cook, P.R.3
-
22
-
-
50649118115
-
High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay
-
Dolken L, Ruzsics Z, Radle B, Friedel CC, Zimmer R, et al. (2008) High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. RNA 14: 1959-1972.
-
(2008)
RNA
, vol.14
, pp. 1959-1972
-
-
Dolken, L.1
Ruzsics, Z.2
Radle, B.3
Friedel, C.C.4
Zimmer, R.5
-
23
-
-
77449101855
-
Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia
-
Cierpicki T, Risner LE, Grembecka J, Lukasik SM, Popovic R, et al. Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. Nat Struct Mol Biol 17: 62-68.
-
Nat Struct Mol Biol
, vol.17
, pp. 62-68
-
-
Cierpicki, T.1
Risner, L.E.2
Grembecka, J.3
Lukasik, S.M.4
Popovic, R.5
-
24
-
-
2642552304
-
Molecular heterogeneity in AML/MDS patients with 3q21q26 rearrangements
-
Lahortiga I, Vazquez I, Agirre X, Larrayoz MJ, Vizmanos JL, et al. (2004) Molecular heterogeneity in AML/MDS patients with 3q21q26 rearrangements. Genes, chromosomes & cancer 40: 179-189.
-
(2004)
Genes, Chromosomes & Cancer
, vol.40
, pp. 179-189
-
-
Lahortiga, I.1
Vazquez, I.2
Agirre, X.3
Larrayoz, M.J.4
Vizmanos, J.L.5
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