-
1
-
-
63449088758
-
Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion
-
Miyara M, Wing K, Sakaguchi S: Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion. J Allergy Clin Immunol 2009;123:749-55.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 749-55
-
-
Miyara, M.1
Wing, K.2
Sakaguchi, S.3
-
3
-
-
33846980131
-
Epigenetic control of the foxp3 locus in regulatory T cells
-
Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K, Chang HD, Bopp T, Schmitt E, Klein-Hessling S, Serfling E, Hamann A, Huehn J: Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 2007;5:e38.
-
(2007)
PLoS Biol
, vol.5
-
-
Floess, S.1
Freyer, J.2
Siewert, C.3
Baron, U.4
Olek, S.5
Polansky, J.6
Schlawe, K.7
Chang, H.D.8
Bopp, T.9
Schmitt, E.10
Klein-Hessling, S.11
Serfling, E.12
Hamann, A.13
Huehn, J.14
-
4
-
-
45449095936
-
FOXP3 promoter demethylation reveals the committed Treg population in humans
-
Janson PC, Winerdal ME, Marits P, Thorn M, Ohlsson R, Winqvist O: FOXP3 promoter demethylation reveals the committed Treg population in humans. PLoS ONE 2008;3:e1612.
-
(2008)
PLoS ONE
, vol.3
-
-
Janson, P.C.1
Winerdal, M.E.2
Marits, P.3
Thorn, M.4
Ohlsson, R.5
Winqvist, O.6
-
5
-
-
58849118836
-
Epigenetic control of FOXP3 expression: The key to a stable regulatory T-cell lineage?
-
Huehn J, Polansky JK, Hamann A: Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? Nat Rev Immunol 2009;9: 83-9.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 83-89
-
-
Huehn, J.1
Polansky, J.K.2
Hamann, A.3
-
6
-
-
78149419897
-
T regulatory cells in cord blood - FOXP3 demethylation as reliable quantitative marker
-
Liu J, Lluis A, Illi S, Layland L, Olek S, von Mutius E, Schaub B: T regulatory cells in cord blood - FOXP3 demethylation as reliable quantitative marker. PLoS ONE 2010;5:e13267.
-
(2010)
PLoS ONE
, Issue.5
-
-
Liu, J.1
Lluis, A.2
Illi, S.3
Layland, L.4
Olek, S.5
Von Mutius, E.6
Schaub, B.7
-
7
-
-
64049118001
-
Comparison of stable human Treg and Th clones by transcriptional profiling
-
Stockis J, Fink W, Francois V, Connerotte T, de Smet C, Knoops L, van der Bruggen P, Coulie PG, Lucas S: Comparison of stable human Treg and Th clones by transcriptional profiling. Eur J Immunol 2009;39:869-82.
-
(2009)
Eur J Immunol
, vol.39
, pp. 869-882
-
-
Stockis, J.1
Fink, W.2
Francois, V.3
Connerotte, T.4
De Smet, C.5
Knoops, L.6
Van Der Bruggen, P.7
Coulie, P.G.8
Lucas, S.9
-
8
-
-
66249115337
-
The CD4+ T-cell response of melanoma patients to a MAGEA3 peptide vaccine involves potential regulatory T cells
-
François V, Ottaviani S, Renkvist N, Stockis J, Schuler G, Thielemans K, Colau D, Marchand M, Boon T, Lucas S, van der Bruggen P: The CD4+ T-cell response of melanoma patients to a MAGEA3 peptide vaccine involves potential regulatory T cells. Cancer Res 2009;69:4335-45.
-
(2009)
Cancer Res
, vol.69
, pp. 4335-4345
-
-
François, V.1
Ottaviani, S.2
Renkvist, N.3
Stockis, J.4
Schuler, G.5
Thielemans, K.6
Colau, D.7
Marchand, M.8
Boon, T.9
Lucas, S.10
Van Der Bruggen, P.11
-
9
-
-
78149408519
-
Methylation matters: Binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
-
Polansky JK, Schreiber L, Thelemann C, Ludwig L, Kruger M, Baumgrass R, Cording S, Floess S, Hamann A, Huehn J: Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells. J Mol Med 2010;88:1029-40.
-
(2010)
J Mol Med
, vol.88
, pp. 1029-1040
-
-
Polansky, J.K.1
Schreiber, L.2
Thelemann, C.3
Ludwig, L.4
Kruger, M.5
Baumgrass, R.6
Cording, S.7
Floess, S.8
Hamann, A.9
Huehn, J.10
-
10
-
-
50549098084
-
Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression
-
Wang R, Wan Q, Kozhaya L, Fujii H, Unutmaz D: Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS One 2008;3:e27705.
-
(2008)
PLoS One
, vol.3
-
-
Wang, R.1
Wan, Q.2
Kozhaya, L.3
Fujii, H.4
Unutmaz, D.5
-
11
-
-
69449086689
-
Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells
-
Wang R, Kozhaya L, Mercer F, Khaitan A, Fujii H, Unutmaz D: Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A 2009;106:13439-44.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13439-13444
-
-
Wang, R.1
Kozhaya, L.2
Mercer, F.3
Khaitan, A.4
Fujii, H.5
Unutmaz, D.6
-
12
-
-
70449411313
-
GARP: A key receptor controlling FOXP3 in human regulatory T cells
-
Probst-Kepper M, Geffers R, Kröger A, Viegas N, Erck C, Hecht HJ, Lünsdorf H, Roubin R, Moharregh-Khiabani D, Wagner K, Ocklenburg F, Jeron A, Garritsen H, Arstila TP, Kekäläinen E, Balling R, Hauser H, Buer J, Weiss S: GARP: a key receptor controlling FOXP3 in human regulatory T cells. J Cell Mol Med 2009;13:3343-57.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 3343-3357
-
-
Probst-Kepper, M.1
Geffers, R.2
Kröger, A.3
Viegas, N.4
Erck, C.5
Hecht, H.J.6
Lünsdorf, H.7
Roubin, R.8
Moharregh-Khiabani, D.9
Wagner, K.10
Ocklenburg, F.11
Jeron, A.12
Garritsen, H.13
Arstila, T.P.14
Kekäläinen, E.15
Balling, R.16
Hauser, H.17
Buer, J.18
Weiss, S.19
-
13
-
-
73249123203
-
Membrane protein GARP is a receptor for latent TGF-β on the surface of activated human Treg
-
Stockis J, Colau D, Coulie PG, Lucas S: Membrane protein GARP is a receptor for latent TGF-β on the surface of activated human Treg. Eur J Immunol 2009;39:3315-22.
-
(2009)
Eur J Immunol
, vol.39
, pp. 3315-22
-
-
Stockis, J.1
Colau, D.2
Coulie, P.G.3
Lucas, S.4
-
14
-
-
69449085219
-
GARP (LRRC32) is essential for the surface expression of latent TGF-βon platelets and activated FOXP3+ regulatory T cells
-
Tran DQ, Andersson J, Wang R, Ramsey H, Unutmaz D, Shevach EM: GARP (LRRC32) is essential for the surface expression of latent TGF-βon platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A 2009;106:13445-50.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13445-13450
-
-
Tran, D.Q.1
Andersson, J.2
Wang, R.3
Ramsey, H.4
Unutmaz, D.5
Shevach, E.M.6
-
15
-
-
77249105101
-
FOXP3: Required but not sufficient. The role of GARP (LRRC32) as a safeguard of the regulatory phenotype
-
Probst-Kepper M, Balling R, Buer J: FOXP3: required but not sufficient. the role of GARP (LRRC32) as a safeguard of the regulatory phenotype. Curr Mol Med 2010;10:533-9.
-
(2010)
Curr Mol Med
, vol.10
, pp. 533-539
-
-
Probst-Kepper, M.1
Balling, R.2
Buer, J.3
-
16
-
-
73249141893
-
The Tregs' world according to GARP
-
Battaglia M, Roncarolo MG: The Tregs' world according to GARP. Eur J Immunol 2009;39:3296-300.
-
(2009)
Eur J Immunol
, vol.39
, pp. 3296-3300
-
-
Battaglia, M.1
Roncarolo, M.G.2
-
17
-
-
67650090496
-
Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
-
Schmidl C, Klug M, Boeld TJ, Andreesen R, Hoffmann P, Edinger M, Rehli M: Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity. Genome Res 2009;19:1165-74.
-
(2009)
Genome Res
, vol.19
, pp. 1165-1174
-
-
Schmidl, C.1
Klug, M.2
Boeld, T.J.3
Andreesen, R.4
Hoffmann, P.5
Edinger, M.6
Rehli, M.7
-
18
-
-
78650642538
-
Peroxisome proliferator-activated receptor and agonists together with TGF-βconvert human CD4+CD25- T cells into functional Foxp3+ regulatory T cells
-
Lei J, Hasegawa H, Matsumoto T, Yasukawa M: Peroxisome proliferator-activated receptor and agonists together with TGF-βconvert human CD4+CD25- T cells into functional Foxp3+ regulatory T cells. J Immunol 2010;185:7186-98.
-
(2010)
J Immunol
, vol.185
, pp. 7186-7198
-
-
Lei, J.1
Hasegawa, H.2
Matsumoto, T.3
Yasukawa, M.4
-
19
-
-
33745167318
-
UBD, a downstream element of FOXP3, allows the identification of LGALS3, a new marker of human regulatory T cells
-
DOI 10.1038/labinvest.3700432, PII 3700432
-
Ocklenburg F, Moharregh-Khiabani D, Geffers R, Janke V, Pfoertner S, Garritsen H, Groebe L, Klempnauer J, Dittmar KE, Weiss S, Buer, Probst-Kepper M: UBD, a downstream element of FOXP3, allows the identification of LGALS3, a new marker of human regulatory T cells. Lab Invest 2006;86:724-37. (Pubitemid 43901669)
-
(2006)
Laboratory Investigation
, vol.86
, Issue.7
, pp. 724-737
-
-
Ocklenburg, F.1
Moharregh-Khiabani, D.2
Geffers, R.3
Janke, V.4
Pfoertner, S.5
Garritsen, H.6
Groebe, L.7
Klempnauer, J.8
Dittmar, K.E.J.9
Weiss, S.10
Buer, J.11
Probst-Kepper, M.12
-
20
-
-
33747303831
-
Signatures of human regulatory T cells: An encounter with old friends and new players
-
Pfoertner S, Jeron A, Probst-Kepper M, Guzman CA, Hansen W, Westendorf AM, Toepfer T, Schrader AJ, Franzke A, Buer J, Geffers R: Signatures of human regulatory T cells: an encounter with old friends and new players. Genome Biol 2006;7:R54.
-
(2006)
Genome Biol
, vol.7
-
-
Pfoertner, S.1
Jeron, A.2
Probst-Kepper, M.3
Guzman, C.A.4
Hansen, W.5
Westendorf, A.M.6
Toepfer, T.7
Schrader, A.J.8
Franzke, A.9
Buer, J.10
Geffers, R.11
-
21
-
-
0025743732
-
'Touchdown' PCR to circumvent spurious priming during gene amplification
-
Don RH, Cox PT, Wainwright BJ, Baker K, Mattick JS: 'Touchdown' PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res 1991;19:4008.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 4008
-
-
Don, R.H.1
Cox, P.T.2
Wainwright, B.J.3
Baker, K.4
Mattick, J.S.5
-
22
-
-
34548755672
-
+ conventional T cells
-
DOI 10.1002/eji.200737594
-
Baron U, Floess S, Wieczorek G, Baumann K, Grutzkau A, Dong J, Thiel A, Boeld TJ, Hoffmann P, Edinger M, Turbachova I, Hamann A, Olek S, Huehn J: DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. Eur J Immunol 2007;37:2378-89. (Pubitemid 47423608)
-
(2007)
European Journal of Immunology
, vol.37
, Issue.9
, pp. 2378-2389
-
-
Baron, U.1
Floess, S.2
Wieczorek, G.3
Baumann, K.4
Grutzkau, A.5
Dong, J.6
Thiel, A.7
Boeld, T.J.8
Hoffmann, P.9
Edinger, M.10
Turbachova, I.11
Hamann, A.12
Olek, S.13
Huehn, J.14
-
23
-
-
37549041262
-
Atypical Angelman syndrome with macrocephaly due to a familial imprinting center deletion
-
Ronan A, Buiting K, Dudding T: Atypical Angelman syndrome with macrocephaly due to a familial imprinting center deletion. Am J Med Genet A 2008;146A:78-82.
-
(2008)
Am J Med Genet A
, vol.146 A
, pp. 78-82
-
-
Ronan, A.1
Buiting, K.2
Dudding, T.3
-
24
-
-
64249157351
-
Epigenetic reprogramming and induced pluripotency
-
Hochedlinger K, Plath K: Epigenetic reprogramming and induced pluripotency. Development 2009;136:509-23.
-
(2009)
Development
, vol.136
, pp. 509-523
-
-
Hochedlinger, K.1
Plath, K.2
-
25
-
-
47249102067
-
+ T-regulatory cells: Toward therapy for human diseases
-
DOI 10.1111/j.1600-065X.2008.00634.x
-
Allan SE, Broady R, Gregori S, Himmel ME, Locke N, Roncarolo MG, Bacchetta R, Levings MK: CD4+ T-regulatory cells: toward therapy for human diseases. Immunol Rev 2008;223:391-421. (Pubitemid 351986179)
-
(2008)
Immunological Reviews
, vol.223
, Issue.1
, pp. 391-421
-
-
Allan, S.E.1
Broady, R.2
Gregori, S.3
Himmel, M.E.4
Locke, N.5
Roncarolo, M.G.6
Bacchetta, R.7
Levings, M.K.8
-
26
-
-
27144472258
-
In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunity
-
DOI 10.1038/sj.gt.3302567, PII 3302567
-
Loser K, Hansen W, Apelt J, Balkow S, Buer J, Beissert S: In vitro generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunity. Gene Ther 2005;12:1294-304. (Pubitemid 43084485)
-
(2005)
Gene Therapy
, vol.12
, Issue.17
, pp. 1294-1304
-
-
Loser, K.1
Hansen, W.2
Apelt, J.3
Balkow, S.4
Buer, J.5
Beissert, S.6
-
27
-
-
12744262844
-
Antigenspecific FoxP3-transduced T-cells can control established type 1 diabetes
-
Jaeckel E, von Boehmer H, Manns MP: Antigenspecific FoxP3-transduced T-cells can control established type 1 diabetes. Diabetes 2005;54:306-10.
-
(2005)
Diabetes
, vol.54
, pp. 306-310
-
-
Jaeckel, E.1
Von Boehmer, H.2
Manns, M.P.3
-
28
-
-
33745294108
-
+ regulatory T cells in vivo
-
Hansen W, Loser K, Westendorf AM, Bruder D, Pfoertner S, Siewert C, Huehn J, Beissert S, Buer J: G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo. J Immunol 2006; 177:209-15. (Pubitemid 43939132)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 209-215
-
-
Hansen, W.1
Loser, K.2
Westendorf, A.M.3
Bruder, D.4
Pfoertner, S.5
Siewert, C.6
Huehn, J.7
Beissert, S.8
Buer, J.9
-
29
-
-
77953120130
-
Inflammation in vivo is modulated by GPR83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cells
-
Hansen W, Westendorf AM, Toepfer T, Mauel S, Geffers R, Gruber AD, Buer J: Inflammation in vivo is modulated by GPR83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cells. Genes Immun 2010;11:357-61.
-
(2010)
Genes Immun
, vol.11
, pp. 357-61
-
-
Hansen, W.1
Westendorf, A.M.2
Toepfer, T.3
Mauel, S.4
Geffers, R.5
Gruber, A.D.6
Buer, J.7
-
30
-
-
44449086017
-
CD83 expression in CD4+ T cells modulates inflammation and autoimmunity
-
Reinwald S, Wiethe C, Westendorf AM, Breloer M, Probst-Kepper M, Fleischer B, Steinkasserer A, Buer J, Hansen W: CD83 expression in CD4+ T cells modulates inflammation and autoimmunity. J Immunol 2008;180:5890-7.
-
(2008)
J Immunol
, vol.180
, pp. 5890-5897
-
-
Reinwald, S.1
Wiethe, C.2
Westendorf, A.M.3
Breloer, M.4
Probst-Kepper, M.5
Fleischer, B.6
Steinkasserer, A.7
Buer, J.8
Hansen, W.9
-
31
-
-
33646168597
-
FOXP3: Of mice and men
-
Ziegler SF: FOXP3: of mice and men. Annu Rev Immunol 2006;24:209-26.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 209-226
-
-
Ziegler, S.F.1
|