Adenosine receptors and fibrosis: A translational review

F1000 Biology Reports

Volumn 3, Issue 1, 2011, Pages

  Cronstein, Bruce N ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE RECEPTOR; BLEOMYCIN; CAFFEINE; COLLAGEN; CYCLIC AMP; PURINE NUCLEOSIDE; VASCULOTROPIN;

ADAPTIVE IMMUNITY; ANGIOGENESIS; FIBROSIS; HEART MUSCLE FIBROSIS; HUMAN; INFLAMMATION; LIVER DISEASE; LIVER FIBROSIS; LUNG FIBROSIS; MORTALITY; NONHUMAN; PERITONEAL FIBROSIS; REVIEW; SKIN FIBROSIS;

EID: 80053512560     PISSN: 17404118     EISSN: 1757594X     Source Type: Journal    
DOI: 10.3410/B3-21     Document Type: Review

References (44)

1. Cronstein BN, Kramer SB, Weissmann G, Hirschhorn R: Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med 1983, 158:1160-77.
2. Haskó G, Linden J, Cronstein B, Pacher P: Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 2008, 7:759-70.
3. Leibovich SJ, Chen JF, Pinhal-Enfield G, Belem PC, Elson G, Rosania A, Ramanathan M, Montesinos C, Jacobson M, Schwarzschild MA, Fink JS, Cronstein B: Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. Am J Pathol 2002, 160:2231-44.
4. Macedo L, Pinhal-Enfield G, Alshits V, Elson G, Cronstein BN, Leibovich SJ: Wound healing is impaired in MyD88-deficient mice: a role for MyD88 in the regulation of wound healing by adenosine A2A receptors. Am J Pathol 2007, 171:1774-88.
5. Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ, Leibovich SJ: An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors. Am J Pathol 2003, 163:711-21.
6. Montesinos MC, Gadangi P, Longaker M, Sung J, Levine J, Nilsen D, Reibman J, Li M, Jiang CK, Hirschhorn R, Recht PA, Ostad E, Levin RI, Cronstein BN: Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors. J Exp Med 1997, 186:1615-20.
7. Berne RM, Belardinelli L: Effects of hypoxia and ischaemia on coronary vascular resistance, A-V node conduction and S-A node excitation. Acta Med Scand Suppl 1985, 694:9-19. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
8. Gawlowski DM, Durán WN: Dose-related effects of adenosine and bradykinin on microvascular permselectivity to macromolecules in the hamster cheek pouch. Circ Res 1986, 58:348-55. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
9. Des Rosiers C, Nees S: Functional evidence for the presence of adenosine A2-receptors in cultured coronary endothelial cells. Naunyn Schmiedebergs Arch Pharmacol 1987, 336:94-8. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
10. Bache RJ, Dai XZ, Schwartz JS, Homans DC: Role of adenosine in coronary vasodilation during exercise. Circ Res 1988, 62:846-53.
11. Meininger CJ, Schelling ME, Granger HJ: Adenosine and hypoxia stimulate proliferation and migration of endothelial cells. Am J Physiol 1988, 255:H554-62. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
12. Grant MB, Tarnuzzer RW, Caballero S, Ozeck MJ, Davis MI, Spoerri PE, Feoktistov I, Biaggioni I, Shryock JC, Belardinelli L: Adenosine receptor activation induces vascular endothelial growth factor in human retinal endothelial cells. Circ Res 1999, 85:699-706. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
13. Grant MB, Davis MI, Caballero S, Feoktistov I, Biaggioni I, Belardinelli L: Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation. Invest Ophthalmol Vis Sci 2001, 42:2068-73. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
14. Montesinos MC, Desai A, Chen JF, Yee H, Schwarzschild MA, Fink JS, Cronstein BN: Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors. Am J Pathol 2002, 160:2009-18.
15. Desai A, Victor-Vega C, Gadangi S, Montesinos MC, Chu CC, Cronstein BN: Adenosine A2A receptor stimulation increases angiogenesis by down-regulating production of the antiangiogenic matrix protein thrombospondin 1. Mol Pharmacol 2005, 67:1406-13.
16. Ryzhov S, McCaleb JL, Goldstein AE, Biaggioni I, Feoktistov I: Role of adenosine receptors in the regulation of angiogenic factors and neovascularization in hypoxia. J Pharmacol Exp Ther 2007, 320:565-72. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
17. Leibovich SJ, Chen JF, Pinhal-Enfield G, Belem PC, Elson G, Rosania A, Ramanathan M, Montesinos C, Jacobson M, Schwarzschild MA, Fink JS, Cronstein B: Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. Am J Pathol 2002, 160:2231-44.
18. Montesinos MC, Shaw JP, Yee H, Shamamian P, Cronstein BN: Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis. Am J Pathol 2004, 164:1887-92.
19. Ahmed AH, Jacobson KA, Kim J, Heppel LA: Presence of both A1 and A2a adenosine receptors in human cells and their interaction. Biochem Biophys Res Commun 1995, 208:871-8. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
20. Chan ES, Fernandez P, Merchant AA, Montesinos MC, Trzaska S, Desai A, Tung CF, Khoa DN, Pillinger MH, Reiss AB, Tomic-Canic M, Chen JF, Schwarzschild MA, Cronstein BN: Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma. Arthritis Rheum 2006, 54:2632-42.
21. Blackburn MR, Lee CG, Young HW, Zhu Z, Chunn JL, Kang MJ, Banerjee SK, Elias JA: Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. J Clin Invest 2003, 112:332-44. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
22. Schneider DJ, Lindsay JC, Zhou Y, Molina JG, Blackburn MR: Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease. FASEB J 2010, 24:70-80. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
23. Ma B, Blackburn MR, Lee CG, Homer RJ, Liu W, Flavell RA, Boyden L, Lifton RP, Sun CX, Young HW, Elias JA: Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest 2006, 116:1274-83. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
24. Peng Z, Borea PA, Varani K, Wilder T, Yee H, Chiriboga L, Blackburn MR, Azzena G, Resta G, Cronstein BN: Adenosine signaling contributes to ethanol-induced fatty liver in mice. J Clin Invest 2009, 119:582-94.
25. Peng Z, Fernandez P, Wilder T, Yee H, Chiriboga L, Chan ES, Cronstein BN: Ecto-5′-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis. FASEB J 2008, 22:2263-72.
26. Chan ES, Montesinos MC, Fernandez P, Desai A, Delano DL, Yee H, Reiss AB, Pillinger MH, Chen JF, Schwarzschild MA, Friedman SL, Cronstein BN: Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis. Br J Pharmacol 2006, 148:1144-55.
27. Sohail MA, Hashmi AZ, Hakim W, Watanabe A, Zipprich A, Groszmann RJ, Dranoff JA, Torok NJ, Mehal WZ: Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition. Hepatology 2009, 49:185-94. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
28. Hashmi AZ, Hakim W, Kruglov EA, Watanabe A, Watkins W, Dranoff JA, Mehal WZ: Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 2007, 292:G395-401. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
29. Che J, Chan ES, Cronstein BN: Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway. Mol Pharmacol 2007, 72:1626-36.
30. Tofovic SP, Salah EM, Jackson EK, Melhem M: Early renal injury induced by caffeine consumption in obese, diabetic ZSF1 rats. Ren Fail 2007, 29:891-902. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
31. Klatsky AL, Morton C, Udaltsova N, Friedman GD: Coffee, cirrhosis, and transaminase enzymes. Arch Intern Med 2006, 166:1190-5. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
32. Higdon JV, Frei B: Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr 2006, 46:101-23. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
33. Ruhl CE, Everhart JE: Coffee and tea consumption are associated with a lower incidence of chronic liver disease in the United States. Gastroenterology 2005, 129:1928-36. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
34. Tverdal A, Skurtveit S: Coffee intake and mortality from liver cirrhosis. Ann Epidemiol 2003, 13:419-23. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
35. Corrao G, Zambon A, Bagnardi V, D'Amicis A, Klatsky A; Collaborative SIDECIR Group: Coffee, caffeine, and the risk of liver cirrhosis. Ann Epidemiol 2001, 11:458-65. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
36. Sharp DS, Everhart JE, Benowitz NL: Coffee, alcohol, and the liver. Ann Epidemiol 1999, 9:391-3. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
37. Tanaka K, Tokunaga S, Kono S, Tokudome S, Akamatsu T, Moriyama T, Zakouji H: Coffee consumption and decreased serum gamma-glutamyltransferase and aminotransferase activities among male alcohol drinkers. Int J Epidemiol 1998, 27:438-43. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
38. Corrao G, Lepore AR, Torchio P, Valenti M, Galatola G, D'Amicis A, Aricó S, di Orio F: The effect of drinking coffee and smoking cigarettes on the risk of cirrhosis associated with alcohol consumption. A case-control study. Provincial Group for the Study of Chronic Liver Disease. Eur J Epidemiol 1994, 10:657-64. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
39. Klatsky AL, Armstrong MA, Friedman GD: Coffee, tea, and mortality. Ann Epidemiol 1993, 3:375-81. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
40. Klatsky AL, Armstrong MA: Alcohol, smoking, coffee, and cirrhosis. Am J Epidemiol 1992, 136:1248-57. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
41. Nakav S, Kachko L, Vorobiov M, Rogachev B, Chaimovitz C, Zlotnik M, Douvdevani A: Blocking adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models. Nephrol Dial Transplant 2009, 24:2392-9. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
42. Zhou Y, Murthy JN, Zeng D, Belardinelli L, Blackburn MR: Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. PLoS One 2010, 5:e9224. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
43. Dubey RK, Gillespie DG, Jackson EK: Adenosine inhibits collagen and protein synthesis in cardiac fibroblasts: role of A2B receptors. Hypertension 1998, 31:943-8. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011
44. Wakeno M, Minamino T, Seguchi O, Okazaki H, Tsukamoto O, Okada K, Hirata A, Fujita M, Asanuma H, Kim J, Komamura K, Takashima S, Mochizuki N, Kitakaze M: Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats. Circulation 2006, 114:1923-32. F1000 Factor 6 Evaluated by Bruce Cronstein 19 Sep 2011