The epigenetic regulation of stem cell factors in hepatic stellate cells

Stem Cells and Development

Volumn 20, Issue 10, 2011, Pages 1687-1699

  Reister, Sven ^a   Kordes, Claus ^a   Sawitza, Iris ^a   Häussinger, Dieter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CD133 ANTIGEN; HISTONE H3; LYSINE; NESTIN; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; STEM CELL FACTOR;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; DEMETHYLATION; DNA METHYLATION; EMBRYONIC STEM CELL; EPIGENETICS; HISTONE METHYLATION; IMMUNOPRECIPITATION; LIVER CELL; LIVER CELL CARCINOMA; LIVER REGENERATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; UMBILICAL CORD BLOOD;

ANIMALS; ANTIGENS, CD; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; EPIGENESIS, GENETIC; FETAL BLOOD; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOPROTEINS; HEPATIC STELLATE CELLS; HISTONES; INTERMEDIATE FILAMENT PROTEINS; LIVER REGENERATION; MALE; NERVE TISSUE PROTEINS; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELL FACTOR; STEM CELLS;

RATTUS;

EID: 80053413477     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2010.0418     Document Type: Article

References (43)

1. Riggs AD and TN Porter. (1996). Overview of genetic mechanisms. In: Epigenetic Mechanisms of Gene Regulation. RussoVEA, RA Martienssen, AD Riggs, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp 29-45.
2. Riggs AD. (1975). X-inactivation, differentiation and DNA methylation. Cytogenet Cell Genet 14:9-25.
3. Clark-Adams CD, D Norris, MA Osley, JS Fassler and F Winston. (1988). Changes in histone gene dosage alter transcription in yeast. Genes Dev 2:150-159.
4. Verdel A, S Jia, S Gerber, T Sugiyama, S Gygi, SI Grewal and D Moazed. (2004). RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303:672-676. (Pubitemid 38141633)
5. Jahner D, H Stuhlmann, CL Stewart, K Harbers, J Lohler, I Simon and R Jaenisch. (1982). De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature 298:623-628. (Pubitemid 12099716)
6. Holliday R and JE Pugh. (1975). DNA modification mechanisms and gene activity during development. Science 187: 226-232.
7. Bestor TH and VM Ingram. (1983). Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA. Proc Natl Acad Sci USA 80:5559-5563. (Pubitemid 14242888)
8. Li E, TH Bestor and R Jaenisch. (1992). Targeted mutation of DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926.
9. Okano M, DW Bell, DA Haber and E Li. (1999). DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99: 247-257. (Pubitemid 29519904)
10. Li E, C Beard and R Jaenisch. (1993). Role for DNA methylation in genomic imprinting. Nature 366:362-365. (Pubitemid 23349366)
11. Little M and B Wainwright. (1995). Methylation and p16: suppressing the suppressor. Nat Med 7:633-634.
12. Klein WM, BP Wu, S Zhao, H Wu, AJ Klein-Szanto and SR Tahan. (2007). Increased expression of stem cell markers in malignant melanoma. Mod Pathol 20:102-107. (Pubitemid 44967955)
13. Tabu K, K Sasai, T Kimura, L Wang, E Aoyanagi, S Kohsaka, M Tanino, H Nishihara and S Tanaka. (2008). Promoter hypomethylation regulates CD133 expression in human gliomas. Cell Res 18:1037-1046.
14. Baba T, PA Convery, N Matsumura, RS Whitaker, E Kondoh, T Perry, Z Huang, RC Bentley, S Mori, S Fujii, JR Marks, A Berchuck and SK Murphy. (2009). Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. Oncogene 28:209-218.
15. Sen GL, JA Reuter, DE Webster, L Zhu and PA Khavari. (2010). DNMT1 maintains progenitor function in selfrenewing somatic tissue. Nature 463:563-567.
16. Kordes C, I Sawitza, A Müller-Marbach, N Ale-Agha, V Keitel, H Klonowski-Stumpe and D Häussinger. (2007). CD133+ hepatic stellate cells are progenitor cells. Biochem Biophys Res Commun 352:410-417. (Pubitemid 44838502)
17. Jackson M, A Krassowska, N Gilbert, T Chevassut, L Forrester, J Ansell and B Ramsahoye. (2004). Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol Cell Biol 20:8862-8871. (Pubitemid 39313892)
18. Gard A, F White and G Dutton. (1985). Extra-neural glial fibrillary acidic protein (GFAP) immunoreactivity in perisinusoidal stellate cells of rat liver. J Neuroimmunol 8:359-375. (Pubitemid 15025262)
19. Sawitza I, C Kordes, S Reister and D Häussinger. (2009). The niche of stellate cells within rat liver. Hepatology 50:1617-1624.
20. Niki T, M Pekny, K Hellemans, P De Bleser, K Van Den Berg, F Vaeyens, E Quartier, F Schutt and A Geerts. (1999). Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells. Hepatology 29:520-527. (Pubitemid 29088457)
21. Wiese C, A Rolletschek, G Kania, P Blyszczuk, KV Tarasov, Y Tarasova, RP Wersto, KR Boheler and AM Wobus. (2004). Nestin Expression-a property of multi-lineage progenitor cells? Cell Mol Life Sci 61:2510-2522. (Pubitemid 39586514)
22. Tatematsu M, RH Ho, T Kaku, JK Ekem and E Farber. (1984). Studies on the proliferation and fate of oval cells in the liver of rats treated with 2-acetylaminofluorene and partial hepatectomy. Am J Pathol 114:418-430. (Pubitemid 14151579)
23. Mann J, F Oakley, F Akiboye, A Elsharkawy, AW Thorne and DA Mann. (2007). Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis. Cell Death Differ 14:275-285. (Pubitemid 46092230)
24. Mann J, DC Chu, A Maxwell, F Oakley, NL Zhu, H Tsukamoto and DA Mann. (2010). MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology 138:705-714.
25. Kordes C, I Sawitza and D Häussinger. (2009). Hepatic and pancreatic stellate cells in focus. Biol Chem 390:1003-1012.
26. Nyfeler Y, RD Kirch, N Mantei, DP Leone, F Radtke, U Suter and V Tayler. (2005). Jagged1 signals in the postnatal subventricular zone are required for neural stem cell selfrenewal. EMBO J 24:3504-3515. (Pubitemid 41486787)
27. Karanu FN, L Yuefei, L Gallacher, S Sakano and M Bhatia. (2003). Differential response of primitive human CD34-and CD34+ hematopoetic cells to the Notch ligand Jagged-1. Leukemia 17:1366-1374. (Pubitemid 36857345)
28. Hendriks HFJ, WA Verhoofstad, A Brouwer, AM DeLeeuw and DL Knook. (1985). Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver. Exp Cell Res 160: 138-149. (Pubitemid 16227414)
29. Berry MN and DS Friend. (1969). High-yield preparation of isolated rat liver parenchymal cells. A biochemical and fine structural study. J Cell Biol 43:506-520.
30. Knook DL and EC Sleyster. (1976). Separation of Kupffer and endothelial cells of the rat liver by centrifugal elutriation. Exp Cell Res 99:444-449.
31. Higgins GM and RM Anderson. (1931). Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol Lab Med 12:186-202.
32. Pfaffl MW. (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acid Res 29: 2003-2007.
33. Dignam JD, RM Lebovitz and RG Roederer. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acid Res 11:1475-1489.
34. Bradford MM. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Ann Biochem 7: 248-254.
35. Li LC and R Dahiya. (2002). MethPrimer: designing Primers for methylation PCRs. Bioinformatics 18:1427-1431. (Pubitemid 35414532)
36. Yang L, A Jung, A Omenetti, RP Witek, SS Choi, HM Vandongen, J Huang, GD Alpini and AM Diehl. (2008). Fatemapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers. Stem Cells 26:2104-2113.
37. Kordes C, I Sawitza and D Häussinger. (2008). Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells. Biochem Biophys Res Commun 367:116-123.
38. Takenobu H, O Shimozato, T Nakamura, H Ochiai, Y Yamaguchi, M Ohira, A Nakagawara and T Kamijo. (2011). CD133 suppresses neuroblastoma cell differentiation via signal pathway modification. Oncogene 30:97-105.
39. Walker L, M Lynch, S Silverman, J Fraser, J Boulter, G Weinmaster and JC Gasson. (1999). The Notch/Jagged pathway inhibits proliferation of human hematopoietic progenitors in vitro. Stem Cells 17:162-171. (Pubitemid 29226667)
40. Han DW, JT Do, MJ Araúzo-Bravo, SH Lee, A Meissner, HT Lee, R Jaenisch and HR Schöler. (2009). Epigenetic hierarchy governing nestin expression. Stem Cells 27:1088-1097.
41. Kordes C, I Sawitza and D Häussinger. (2011). Stellate cells in the regenerating liver. In: Liver Regeneration. Häussinger D, ed. De Gruyter, Berlin. www.degruyter.de/cont/fb/na/ detail.cfm?id = IS-9783110250787-1
42. Kleeberger W, GS Bova, ME Nielsen, M Herawi, AY Chuang, JI Epstein and DM Berman. (2007). Roles for the stem cell associated intermediate filament Nestin in prostate cancer migration and metastasis. Cancer Res 67:9199-9206. (Pubitemid 47535906)
43. Gleiberman AS, JM Encinas, JL Mignone, T Michurina, MG Rosenfeld and G Enikolopov. (2005). Expression of nestingreen fluorescent protein transgene marks oval cells in the adult liver. Dev Dyn 234:413-421 (Pubitemid 41369151)