Antibacterial Agents and Cystic Fibrosis: Synthesis and Antimicrobial Evaluation of a Series of N-Thiomethylazetidinones

ChemMedChem

Volumn 6, Issue 10, 2011, Pages 1919-1927

  Galletti, Paola ^a   Cocuzza, Clementina E A ^b   Pori, Matteo ^a   Quintavalla, Arianna ^a   Musumeci, Rosario ^b   Giacomini, Daria ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Antibiotics; Azetidinones; Cystic fibrosis; Drug resistant bacteria; Lactams

Indexed keywords

1 (METHYLTHIO) 4 (PHENYLSULFONYL)AZETIDIN 2 ONE; 1 (METHYLTHIO) 4 OXOAZETIDIN 2 YL ETHANETHIOATE; 1 [2 [2 (BENZYLOXY) 2 OXOETHYLIDENE] 1 (METHYLTHIO) 4 OXOAZETIDIN 3 YL]ETHYL 4 HYDROXY 3,5 DIMETHOXYBENZOATE; 1[2 [2 (BENZYLOXY) 2 OXOETHYLIDENE] 1 (METHYLTHIO) 4 OXOAZETIDIN 3 YL)ETHYL] 4 HYDROXYBENZOATE; 3 (1 HYDROXYETHYL) 1 (METHYLTHIO) 4 (PHENYLSULFONYL)AZETIDIN 2 ONE; 3 (1 HYDROXYETHYL) 1 (METHYLTHIO) 4 OXOAZETIDIN 2 YL ACETATE; 3 (1 HYDROXYETHYL) 1 (METHYLTHIO) 4 OXOAZETIDIN 2 YL ETHANETHIOATE; 3 [1 (TERT BUTYLDIMETHYLSILANYLOXY)ETHYL] 1 (METHYLTHIO) 4 (PHENYLSULFONYL)AZETIDIN 2 ONE; 3 [1 (TERT BUTYLDIMETHYLSILANYLOXY)ETHYL] 1 (METHYLTHIO) 4 OXOAZETIDIN 2 YL; 3 [1 (TERT BUTYLDIMETHYLSILANYLOXY)ETHYL] 1 (METHYLTHIO) 4 OXOAZETIDIN 2 YL ACETATE; ANTIINFECTIVE AGENT; AZETIDINONE DERIVATIVE; BENZYL 2 (4 OXOAZETIDIN 2 YLIDENE)ACETATE; BENZYL 2 [3 (1 HYDROXYETHYL) 1 (METHYLTHIO) 4 OXOAZETIDIN 2 YLIDENE]ACETATE; BENZYL 2 [3 [1 (TERT BUTYLDIMETHYLSILANYLOXY)ETHYL] 1 (METHYLTHIO) 4 OXOAZETIDIN 2 YLIDENE]ACETATE; ETHYL 2 [1 (METHYLTHIO) 4 OXOAZETIDIN 2 YL]ACETATE; ETHYL 2 [1 (METHYLTHIO) 4 OXOAZETIDIN 2 YLIDENE]ACETATE; ETHYL 2 [3 [1 (TERT BUTYLDIMETHYLSILANYLOXY)ETHYL] 1(METHYLTHIO) 4 OXOAZETIDIN 2 YLIDENE]ACETATE; ETHYL [3 [1 (TERT BUTYLDIMETHYLSILANYLOXY)ETHYL] 1(METHYLTHIO) 4 OXOAZETIDIN 2 YL]ACETATE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CELL GROWTH; CHEMICAL BOND; CONTROLLED STUDY; CYSTIC FIBROSIS; DIASTEREOISOMER; DRUG DETERMINATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; HUMAN; HUMAN CELL; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; PROTEUS MIRABILIS; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; AZETIDINES; CYSTIC FIBROSIS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS;

EID: 80053406779     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100282     Document Type: Article

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