메뉴 건너뛰기




Volumn 12, Issue 1, 2011, Pages

Ethical issues at the interface of clinical care and research practice in pediatric oncology: A narrative review of parents' and physicians' experiences

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOETHICS; CHILD; CLINICAL TRIAL (TOPIC); DECISION MAKING; EMPIRICAL RESEARCH; EQUIPOISE; ETHICS; HUMAN; HUMAN RELATION; ONCOLOGY; PARENT; PARENTAL CONSENT; PATIENT CARE; PEDIATRICS; PERSONNEL; PHYSICIAN; PHYSICIAN ATTITUDE; PSYCHOLOGICAL ASPECT; QUALITATIVE RESEARCH; RESEARCH ETHICS; THERAPEUTIC MISCONCEPTION; VERBAL COMMUNICATION;

EID: 80053366239     PISSN: None     EISSN: 14726939     Source Type: Journal    
DOI: 10.1186/1472-6939-12-18     Document Type: Review
Times cited : (71)

References (67)
  • 2
    • 0036157392 scopus 로고    scopus 로고
    • Cancer statistics
    • 10.3322/canjclin.52.1.23 11814064
    • Cancer statistics. Jemal A, Thomas A, Murray T, Thun M, CA Cancer J Clin 2002 52 23 47 10.3322/canjclin.52.1.23 11814064
    • (2002) CA Cancer J Clin , vol.52 , pp. 23-47
    • Jemal, A.1    Thomas, A.2    Murray, T.3    Thun, M.4
  • 3
    • 0037929453 scopus 로고    scopus 로고
    • Recruiting children into cancer trials - Role of the United Kingdom Children's Cancer Study Group (UKCCSG)
    • DOI 10.1038/sj.bjc.6600990
    • Recruiting children into cancer trials - role of the United Kingdom Children's Cancer Study Group (UKCCSG). Ablett S, Pinkerton CR, United Kingdom Children's Cancer Study Group (UKCCSG), Br J Cancer 2003 88 1661 1665 10.1038/sj.bjc.6600990 12771976 (Pubitemid 36760405)
    • (2003) British Journal of Cancer , vol.88 , Issue.11 , pp. 1661-1665
    • Ablett, S.1    Pinkerton, C.R.2
  • 4
    • 0030870109 scopus 로고    scopus 로고
    • The U.S. pediatric cancer clinical trials programmes: International implications and the way forward
    • DOI 10.1016/S0959-8049(97)00249-9, PII S0959804997002499
    • The US pediatric cancer clinical trials programmes: international implications and the way forward. Bleyer WA, Eur J Cancer 1997 33 1439 47 10.1016/S0959-8049(97)00249-9 9337687 (Pubitemid 27404903)
    • (1997) European Journal of Cancer Part A , vol.33 , Issue.9 , pp. 1439-1447
    • Bleyer, W.A.1
  • 5
    • 3843070167 scopus 로고    scopus 로고
    • European collaboration in trials of new agents for children with cancer
    • DOI 10.1016/j.ejca.2004.05.011, PII S0959804904004186
    • European collaboration in trials of new agents for children with cancer. Ablett S, Doz F, Morland B, Vassal G, New Agents Group of the United Kingdom Children's Cancer Study Group (UKCCSG), Pharmacology Group of the French Society of Paediatric Oncology (SFOP), Eur J Cancer 2004 40 1886 1892 10.1016/j.ejca.2004.05.011 15288291 (Pubitemid 39036764)
    • (2004) European Journal of Cancer , vol.40 , Issue.12 , pp. 1886-1892
    • Ablett, S.1    Doz, F.2    Morland, B.3    Vassal, G.4
  • 6
    • 77957868374 scopus 로고    scopus 로고
    • Reflective equilibrium and empirical data. Third person moral experiences in empirical medical ethics
    • 19438441
    • Reflective equilibrium and empirical data. Third person moral experiences in empirical medical ethics. De Vries MC, Van Leeuwen E, Bioethics 2010 24 9 490 498 19438441
    • (2010) Bioethics , vol.24 , Issue.9 , pp. 490-498
    • De Vries, M.C.1    Van Leeuwen, E.2
  • 7
    • 13444249994 scopus 로고    scopus 로고
    • The birth of the empirical turn in bioethics
    • The Birth of the Empirical Turn in Bioethics. Borry P, Dierickx K, Schotsmans P, Bioethics 2005 19 1 49 71 10.1111/j.1467-8519.2005.00424.x 15812972 (Pubitemid 40215018)
    • (2005) Bioethics , vol.19 , Issue.1 , pp. 49-71
    • Borry, P.1    Schotsmans, P.2    Dierickx, K.3
  • 10
    • 67651219448 scopus 로고    scopus 로고
    • Attitudes of physicians and parents towards discussing infertility risks and semen cryopreservation with male adolescents diagnosed with cancer
    • 10.1002/pbc.22091 19489059
    • Attitudes of physicians and parents towards discussing infertility risks and semen cryopreservation with male adolescents diagnosed with cancer. De Vries MC, Bresters D, Engberts DP, Wit JM, Van Leeuwen E, Pediatr Blood Cancer 2009 53 3 386 91 10.1002/pbc.22091 19489059
    • (2009) Pediatr Blood Cancer , vol.53 , Issue.3 , pp. 386-91
    • De Vries, M.C.1    Bresters, D.2    Engberts, D.P.3    Wit, J.M.4    Van Leeuwen, E.5
  • 11
    • 77953253830 scopus 로고    scopus 로고
    • Norms versus Practice: Pediatric Oncologists' Attitudes towards Involving Adolescents in Decision Making concerning Research Participation
    • 20486177
    • Norms versus Practice: Pediatric Oncologists' Attitudes towards Involving Adolescents in Decision Making concerning Research Participation. De Vries MC, Wit JM, Engberts DP, Kaspers GJL, Van Leeuwen E, Pediatr Blood Cancer 2010 55 1 123 128 20486177
    • (2010) Pediatr Blood Cancer , vol.55 , Issue.1 , pp. 123-128
    • De Vries, M.C.1    Wit, J.M.2    Engberts, D.P.3    Kaspers, G.J.L.4    Van Leeuwen, E.5
  • 12
    • 0034998791 scopus 로고    scopus 로고
    • Including qualitative research in systematic reviews: Opportunities and problems
    • DOI 10.1046/j.1365-2753.2001.00257.x
    • Including qualitative research in systematic reviews: opportunities and problems. Dixon-Woods M, Fitzpatrick R, Roberts K, Journal of Evaluation in Clinical Practice 2001 7 2 125 133 10.1046/j.1365-2753.2001.00257.x 11489038 (Pubitemid 32489006)
    • (2001) Journal of Evaluation in Clinical Practice , vol.7 , Issue.2 , pp. 125-133
    • Dixon-Woods, M.1    Fitzpatrick, R.2    Roberts, K.3
  • 13
    • 15944422498 scopus 로고    scopus 로고
    • Balancing the strengths of systematic and narrative reviews
    • DOI 10.1093/humupd/dmh058
    • Balancing the strengths of systematic narrative reviews. Collins JA, Fauser BCJM, Hum Reprod Update 2005 11 2 103 104 15618290 (Pubitemid 40439504)
    • (2005) Human Reproduction Update , vol.11 , Issue.2 , pp. 103-104
    • Collins, J.A.1    Fauser, B.C.J.M.2
  • 15
    • 0141797654 scopus 로고    scopus 로고
    • A Critique of Clinical Equipoise: Therapeutic Misconception in the Ethics of Clinical Trials
    • 10.2307/3528434 12854452
    • A Critique of Clinical Equipoise: Therapeutic Misconception in the Ethics of Clinical Trials. Miller FG, Brody H, Hastings Cent Rep 2003 33 3 19 28 10.2307/3528434 12854452
    • (2003) Hastings Cent Rep , vol.33 , Issue.3 , pp. 19-28
    • Miller, F.G.1    Brody, H.2
  • 16
    • 0037417240 scopus 로고    scopus 로고
    • The therapeutic orientation to clinical trials
    • DOI 10.1056/NEJMsb030228
    • The Therapeutic Orientation to Clinical Trials. Miller FG, Rosenstein DL, N Engl J Med 2003 348 14 1383 1386 10.1056/NEJMsb030228 12672867 (Pubitemid 36384108)
    • (2003) New England Journal of Medicine , vol.348 , Issue.14 , pp. 1383-1386
    • Miller, F.G.1    Rosenstein, D.L.2
  • 19
    • 60549085392 scopus 로고    scopus 로고
    • The length of consent documents in oncological trials is doubled in twenty years
    • 18922881
    • The length of consent documents in oncological trials is doubled in twenty years. Berger O, Grønberg BH, Sand K, Kaasa S, Loge JH, Ann Oncol 2009 20 2 379 385 18922881
    • (2009) Ann Oncol , vol.20 , Issue.2 , pp. 379-385
    • Berger, O.1    Grønberg, B.H.2    Sand, K.3    Kaasa, S.4    Loge, J.H.5
  • 20
    • 0037456358 scopus 로고    scopus 로고
    • Readability standards for informed-consent forms as compared with actual readability
    • DOI 10.1056/NEJMsa021212
    • Readability standards of informed consent forms as compared with actual readability. Paasche-Orlow MK, Taylor HA, Brancati FL, N Engl J Med 2003 348 721 726 10.1056/NEJMsa021212 12594317 (Pubitemid 36237042)
    • (2003) New England Journal of Medicine , vol.348 , Issue.8 , pp. 721-726
    • Paasche-Orlow, M.K.1    Taylor, H.A.2    Brancati, F.L.3
  • 21
    • 0025157233 scopus 로고
    • Readability of pediatric biomedical research informed consent forms
    • Readability of pediatric biomedical research information consent forms. Tarnowski KJ, Allen DM, Mayhall C, Kelly PA, Pediatrics 1990 85 58 62 2296494 (Pubitemid 20029049)
    • (1990) Pediatrics , vol.85 , Issue.1 , pp. 58-62
    • Tarnowski, K.J.1    Allen, D.M.2    Mayhall, C.3    Kelly, P.A.4
  • 22
    • 0027943564 scopus 로고
    • Are informed consent forms that describe clinical oncology research protocols readable by most patients and their families?
    • Are informed consent forms that describe clinical oncology research protocols readable by most patients and their families? Grossman SA, Piantadosi S, Covahey C, J Clin Oncol 1994 12 2211 2215 7931491 (Pubitemid 24356041)
    • (1994) Journal of Clinical Oncology , vol.12 , Issue.10 , pp. 2211-2215
    • Grossman, S.A.1    Plantadosi, S.2    Covahey, C.3
  • 25
    • 0036201717 scopus 로고    scopus 로고
    • Ethical issues of informed consent: Mothers' experiences enrolling their children in bone marrow transplantation research
    • Ethical issues of informed consent: mothers' experiences enrolling their children in bone marrow transplantation research. Stevens PE, Pletsch PK, Cancer Nurs 2002 25 2 81 87 10.1097/00002820-200204000-00001 11984094 (Pubitemid 34263931)
    • (2002) Cancer Nursing , vol.25 , Issue.2 , pp. 81-87
    • Stevens, P.E.1    Pletsch, P.K.2
  • 27
    • 77957350881 scopus 로고    scopus 로고
    • Parental comprehension and satisfaction in informed consent in paediatric clinical trials: A prospective study on childhood leukaemia
    • 10.1136/adc.2009.180695 20551191
    • Parental comprehension and satisfaction in informed consent in paediatric clinical trials: a prospective study on childhood leukaemia. Chappuy H, Baruchel A, Leverger G, Oudot C, Brethon B, Haouy S, Auvrignon A, Davous D, Doz F, Tréluyer JM, Arch Dis Child 2010 95 10 800 4 10.1136/adc.2009.180695 20551191
    • (2010) Arch Dis Child , vol.95 , Issue.10 , pp. 800-4
    • Chappuy, H.1    Baruchel, A.2    Leverger, G.3    Oudot, C.4    Brethon, B.5    Haouy, S.6    Auvrignon, A.7    Davous, D.8    Doz, F.9    Tréluyer, J.M.10
  • 28
    • 0025610634 scopus 로고
    • Psychological distress in parents consenting to child's bone marrow transplantation
    • 2097010
    • Psychological distress in parents consenting to child's bone marrow transplantation. Dermatis H, Lesko LM, Bone Marrow transplant 1990 6 411 417 2097010
    • (1990) Bone Marrow Transplant , vol.6 , pp. 411-417
    • Dermatis, H.1    Lesko, L.M.2
  • 29
    • 0034457588 scopus 로고    scopus 로고
    • Diagnosis, disclosure, and informed consent: Learning from parents of children with cancer
    • DOI 10.1097/00043426-200001000-00002
    • Diagnosis, disclosure, and informed consent: learning from parents of children with cancer. Levi RB, Marsick R, Drotar D, Kodish ED, J Pediatr Hematol Oncol 2000 22 3 12 10.1097/00043426-200001000-00002 10695815 (Pubitemid 32266831)
    • (2000) Journal of Pediatric Hematology/Oncology , vol.22 , Issue.1 , pp. 3-12
    • Levi, R.B.1    Marsick, R.2    Drotar, D.3    Kodish, E.D.4
  • 30
    • 0028916609 scopus 로고
    • Doctor-patient communication: A review of the literature
    • 10.1016/0277-9536(94)00155-M 7792630
    • Doctor-patient communication: a review of the literature. Ong LM, De Haes JC, Hoos AM, Lammes FB, Soc Sci Med 1995 40 7 903 18 10.1016/0277-9536(94) 00155-M 7792630
    • (1995) Soc Sci Med , vol.40 , Issue.7 , pp. 903-18
    • Ong, L.M.1    De Haes, J.C.2    Hoos, A.M.3    Lammes, F.B.4
  • 32
    • 61849084756 scopus 로고    scopus 로고
    • How do parents experience being asked to enter a child in a randomised controlled trial?
    • 10.1186/1472-6939-10-1 19220889
    • How do parents experience being asked to enter a child in a randomised controlled trial? Shilling V, Young B, BMC Med Ethics 2009 10 1 10.1186/1472-6939-10-1 19220889
    • (2009) BMC Med Ethics , vol.10 , pp. 1
    • Shilling, V.1    Young, B.2
  • 33
    • 0031985017 scopus 로고    scopus 로고
    • Factors that influence parents' decisions to consent to their child's participation in clinical anesthesia research
    • DOI 10.1097/00000539-199801000-00010
    • Factors that influence parents' decisions to consent to their child's participation in clinical anesthesia research. Tait AR, Voepel-Lewis T, Siewert M, Malviya S, Anesth Analg 1998 86 1 50 53 9428850 (Pubitemid 28040089)
    • (1998) Anesthesia and Analgesia , vol.86 , Issue.1 , pp. 50-53
    • Tait, A.R.1    Voepel-Lewis, T.2    Siewert, M.3    Malviya, S.4
  • 34
    • 85047697218 scopus 로고    scopus 로고
    • Parents' perceptions of research with newborns
    • DOI 10.1038/sj/jp/7210608
    • Parents' perceptions of research with newborns. Singhal N, Oberle K, Burgess E, Huber-Okrainec J, J Perinatol 2002 22 1 57 63 10.1038/sj.jp.7210608 11840244 (Pubitemid 34168161)
    • (2002) Journal of Perinatology , vol.22 , Issue.1 , pp. 57-63
    • Singhal, N.1    Oberle, K.2    Burgess, E.3    Huber-Okrainec, J.4
  • 35
    • 35348837154 scopus 로고    scopus 로고
    • Risk perception and decision processes underlying informed consent to research participation
    • DOI 10.1016/j.socscimed.2007.06.021, PII S0277953607003462
    • Risk perception and decision processes underlying informed consent to research participation. Reynolds WW, Nelson RM, Soc Sci Med 2007 65 10 2105 2115 10.1016/j.socscimed.2007.06.021 17689846 (Pubitemid 47593039)
    • (2007) Social Science and Medicine , vol.65 , Issue.10 , pp. 2105-2115
    • Reynolds, W.W.1    Nelson, R.M.2
  • 36
    • 0141992777 scopus 로고    scopus 로고
    • Clinical trials in pediatric cancer: Parental perspectives on informed consent
    • DOI 10.1097/00043426-200310000-00009
    • Clinical trials in pediatric cancer: parental perspectives on informed consent. Kupst MJ, Patenaude AF, Walco GA, Sterling C, J Pediatr Hematol Oncol 2003 25 10 787 790 10.1097/00043426-200310000-00009 14528101 (Pubitemid 37238768)
    • (2003) Journal of Pediatric Hematology/Oncology , vol.25 , Issue.10 , pp. 787-790
    • Kupst, M.J.1    Patenaude, A.F.2    Walco, G.A.3    Sterling, C.4
  • 37
    • 0030839611 scopus 로고    scopus 로고
    • Making sense of randomization; responses of parents of critically ill babies to random allocation of treatment in a clinical trial
    • DOI 10.1016/S0277-9536(97)00063-4, PII S0277953697000634
    • Making sense of randomization; responses of parents of critically ill babies to random allocation of treatment in a clinical trial. Snowdon C, Garcia J, Elbourne D, Soc Sci Med 1997 45 1337 55 10.1016/S0277-9536(97)00063-4 9351153 (Pubitemid 27445491)
    • (1997) Social Science and Medicine , vol.45 , Issue.9 , pp. 1337-1355
    • Snowdon, C.1    Garcia, J.2    Elbourne, D.3
  • 38
    • 23844492536 scopus 로고    scopus 로고
    • Mothers' attitudes to the randomized controlled trial (RCT): The case of acute lymphoblastic leukaemia (ALL) in children
    • DOI 10.1111/j.1365-2214.2005.00538.x
    • Mothers' attitudes to the randomized controlled trial (RCT): the case of acute lymphoblastic leukaemia (ALL) in children. Eiser C, Davies H, Jenney M, Glaser A, Child Care Health Dev 2005 31 5 517 523 10.1111/j.1365-2214.2005. 00538.x 16101646 (Pubitemid 41179464)
    • (2005) Child: Care, Health and Development , vol.31 , Issue.5 , pp. 517-523
    • Eiser, C.1    Davies, H.2    Jenney, M.3    Glaser, A.4
  • 39
    • 59949096359 scopus 로고    scopus 로고
    • Voluntariness of consent to research. A conceptual model
    • 10.1353/hcr.0.0103 19213193
    • Voluntariness of consent to research. A conceptual model. Appelbaum PS, Lidz CW, Klitzman R, Hastings Cent Rep 2009 39 1 30 39 10.1353/hcr.0.0103 19213193
    • (2009) Hastings Cent Rep , vol.39 , Issue.1 , pp. 30-39
    • Appelbaum, P.S.1    Lidz, C.W.2    Klitzman, R.3
  • 40
    • 1442323882 scopus 로고    scopus 로고
    • Will Mothers Discuss Parenting Stress and Depressive Symptoms with Their Child's Pediatrician?
    • DOI 10.1542/peds.113.3.460
    • Will mothers discuss parenting stress and depressive symptoms with their child's pediatrician? Heneghan AM, Mercer M, DeLeone NL, Pediatrics 2004 113 460 467 10.1542/peds.113.3.460 14993535 (Pubitemid 38280784)
    • (2004) Pediatrics , vol.113 , Issue.3 , pp. 460-467
    • Heneghan, A.M.1    Mercer, M.2    DeLeone, N.L.3
  • 41
    • 0023185342 scopus 로고
    • Equipoise and the ethics of clinical research
    • Equipoise and the ethics of clinical research. Freedman B, NEJM 1987 317 3 141 145 10.1056/NEJM198707163170304 3600702 (Pubitemid 17092151)
    • (1987) New England Journal of Medicine , vol.317 , Issue.3 , pp. 141-145
    • Freedman, B.1
  • 42
    • 34247159822 scopus 로고    scopus 로고
    • Clinical equipoise: Foundational requirement or fundamental error?
    • New York: Oxford University Press Steinbock B
    • Clinical equipoise: foundational requirement or fundamental error? London AJ, The Oxford handbook of bioethics New York: Oxford University Press, Steinbock B, 2007 571 596
    • (2007) The Oxford Handbook of Bioethics , pp. 571-596
    • London, A.J.1
  • 43
    • 0038528532 scopus 로고    scopus 로고
    • Indifference of subjects: An alternative to equipoise in randomized clinical trials
    • 10.1017/S0265052502192120 12678091
    • Indifference of subjects: an alternative to equipoise in randomized clinical trials. Veatch RM, Soc Philos Policy 2002 19 2 295 323 10.1017/S0265052502192120 12678091
    • (2002) Soc Philos Policy , vol.19 , Issue.2 , pp. 295-323
    • Veatch, R.M.1
  • 44
    • 0010030912 scopus 로고
    • Philosophical reflections on experimenting with human subjects
    • Philosophical reflections on experimenting with human subjects. Jonas H, Daedalus 1969 98 2 219 247
    • (1969) Daedalus , vol.98 , Issue.2 , pp. 219-247
    • Jonas, H.1
  • 45
    • 77955720341 scopus 로고    scopus 로고
    • Parental involvement in paediatric cancer treatment decisions
    • 10.1111/j.1365-2354.2009.01116.x 19807776
    • Parental involvement in paediatric cancer treatment decisions. McKenna K, Collier J, Hewitt M, Blake H, European Journal of Cancer Care 2010 19 621 630 10.1111/j.1365-2354.2009.01116.x 19807776
    • (2010) European Journal of Cancer Care , vol.19 , pp. 621-630
    • McKenna, K.1    Collier, J.2    Hewitt, M.3    Blake, H.4
  • 46
    • 0020390058 scopus 로고
    • The therapeutic misconception: Informed consent in psychiatric research
    • 10.1016/0160-2527(82)90026-7 6135666
    • The therapeutic misconception: informed consent in psychiatric research. Appelbaum PS, Roth L, Lidz CW, Int J Law Psychiatry 1982 5 319 29 10.1016/0160-2527(82)90026-7 6135666
    • (1982) Int J Law Psychiatry , vol.5 , pp. 319-29
    • Appelbaum, P.S.1    Roth, L.2    Lidz, C.W.3
  • 47
    • 2342464377 scopus 로고    scopus 로고
    • Therapeutic misconception in clinical research: Frequency and risk factors
    • Therapeutic misconception in clinical research: frequency and risk factors. Appelbaum PS, Lidz CW, Grisso T, IRB 2004 26 1 8 15658016 (Pubitemid 41585058)
    • (2004) IRB Ethics and Human Research , vol.26 , Issue.2 , pp. 1-8
    • Appelbaum, P.S.1    Lidz, C.W.2    Grisso, T.3
  • 48
    • 0035944839 scopus 로고    scopus 로고
    • Quality of informed consent in cancer clinical trials: A cross-sectional survey
    • DOI 10.1016/S0140-6736(01)06805-2
    • Quality of informed consent in cancer clinical trials: a cross-sectional survey. Joffe S, Cook EF, Cleary PD, Clark JW, Weeks JC, Lancet 2001 358 1772 1777 10.1016/S0140-6736(01)06805-2 11734235 (Pubitemid 33153003)
    • (2001) Lancet , vol.358 , Issue.9295 , pp. 1772-1777
    • Joffe, S.1    Cook, E.F.2    Cleary, P.D.3    Clark, J.W.4    Weeks, J.C.5
  • 49
    • 0023319217 scopus 로고
    • False hopes and best data: Consent to research and the therapeutic misconception
    • 10.2307/3562038 3667246
    • False hopes and best data: consent to research and the therapeutic misconception. Appelbaum PS, Roth LH, Lidz CW, Benson P, Winslade W, Hastings Cent Rep 1987 17 2 20 24 10.2307/3562038 3667246
    • (1987) Hastings Cent Rep , vol.17 , Issue.2 , pp. 20-24
    • Appelbaum, P.S.1    Roth, L.H.2    Lidz, C.W.3    Benson, P.4    Winslade, W.5
  • 50
    • 0026636643 scopus 로고
    • Integrating conflicting professional roles: Physician participation in randomized clinical trials
    • 10.1016/0277-9536(92)90169-Q 1509310
    • Integrating conflicting professional roles: physician participation in randomized clinical trials. Taylor KM, Soc Sci Med 1992 35 217 224 10.1016/0277-9536(92)90169-Q 1509310
    • (1992) Soc Sci Med , vol.35 , pp. 217-224
    • Taylor, K.M.1
  • 51
    • 0028130499 scopus 로고
    • Fundamental dilemmas of the randomized clinical trial process: Results of a survey of the 1,737 Eastern Cooperative Oncology Group investigators
    • Fundamental dilemmas of the randomized clinical trial process: results of a survey of the 1,737 Eastern Cooperative Oncology Group investigators. Taylor KM, Feldstein ML, Skeel RT, Pandya KJ, Ng P, Carbone PP, J Clin Oncol 1994 12 1796 1805 8083703 (Pubitemid 24349380)
    • (1994) Journal of Clinical Oncology , vol.12 , Issue.9 , pp. 1796-1805
    • Taylor, K.M.1    Feldstein, M.L.2    Skeel, R.T.3    Pandya, K.J.4    Ng, P.5    Carbone, P.P.6
  • 52
    • 0037132709 scopus 로고    scopus 로고
    • Views of American oncologists about the purposes of clinical trials
    • Views of American Oncologists About the Purposes of Clinical Trials. Joffe S, Weeks JC, J Natl Cancer Inst 2002 94 24 1847 1853 10.1093/jnci/94.24. 1847 12488478 (Pubitemid 36104629)
    • (2002) Journal of the National Cancer Institute , vol.94 , Issue.24 , pp. 1847-1853
    • Joffe, S.1    Weeks, J.C.2
  • 53
    • 82755161233 scopus 로고    scopus 로고
    • M.D. Anderson Cancer Center
    • Clinical Trials at the Children's Cancer Hospital. Houston, 2011. M.D. Anderson Cancer Center, http://www.mdanderson.org/patient-and-cancer- information/care-centers-and-clinics/childrens-cancer-hospital/clinical-trials/ index.html
    • Clinical Trials at the Children's Cancer Hospital. Houston, 2011
  • 54
    • 0033976781 scopus 로고    scopus 로고
    • Managed care and oncology: The quality debate
    • Managed care and oncology: the quality debate. Bailes J, J Clin Oncol 2000 18 705 707 10673510 (Pubitemid 30106599)
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.4 , pp. 705-707
    • Bailes, J.1
  • 55
    • 0031923354 scopus 로고    scopus 로고
    • Access to quality cancer care: Consensus statement
    • American Federation of Clinical Oncology Societies 9552076
    • Access to quality cancer care: consensus statement. American Federation of Clinical Oncology Societies, J Clin Oncol 1998 16 1628 1630 9552076
    • (1998) J Clin Oncol , vol.16 , pp. 1628-1630
  • 56
    • 28544452190 scopus 로고    scopus 로고
    • Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group
    • DOI 10.1136/bmj.38628.561123.7C
    • Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group. Kumar A, Soares H, Wells R, Clarke M, Hozo I, Bleyer A, Reaman G, Chalmers I, Djulbegovic B, Children's Oncology Group, BMJ 2005 331 7528 1295 Epub 2005 Nov 18 10.1136/bmj.38628.561123.7C 16299015 (Pubitemid 41746457)
    • (2005) British Medical Journal , vol.331 , Issue.7528 , pp. 1295-1298
    • Kumar, A.1    Soares, H.2    Wells, R.3    Clarke, M.4    Hozo, I.5    Bleyer, A.6    Reaman, G.7    Chalmers, I.8    Djulbegovic, B.9
  • 57
    • 0032765521 scopus 로고    scopus 로고
    • Patterns of care and survival for children with acute lymphoblastic leukaemia diagnosed between 1980 and 1994
    • Patterns of care and survival for children with acute lymphoblastic leukaemia diagnosed between 1980 and 1994. Stiller CA, Eatock EM, Arch Dis Child 1999 81 202 208 10.1136/adc.81.3.202 10451391 (Pubitemid 29398379)
    • (1999) Archives of Disease in Childhood , vol.81 , Issue.3 , pp. 202-208
    • Stiller, C.A.1    Eatock, E.M.2
  • 58
    • 0024433301 scopus 로고
    • Do treatment protocols improve end results? A study of survival of patients with multiple myeloma in Finland
    • Do treatment protocols improve end results? A study of survival of patients with multiple myeloma in Finland. Karjalainen S, Palva I, BMJ 1989 299 1069 1072 10.1136/bmj.299.6707.1069 2511967 (Pubitemid 19262532)
    • (1989) British Medical Journal , vol.299 , Issue.6707 , pp. 1069-1072
    • Karjalainen, S.1    Palva, I.2
  • 59
    • 55049135606 scopus 로고    scopus 로고
    • Outcomes of patients who participate in randomised controlled trials compared to similar patients receiving similar interventions who do not participate
    • Outcomes of patients who participate in randomised controlled trials compared to similar patients receiving similar interventions who do not participate. Vist GE, Bryant D, Somerville L, Birminghem T, Oxman AD, Cochrane Database Syst Rev 2008 16 3 R000009
    • (2008) Cochrane Database Syst Rev , vol.16 , Issue.3
    • Vist, G.E.1    Bryant, D.2    Somerville, L.3    Birminghem, T.4    Oxman, A.D.5
  • 60
    • 0942278952 scopus 로고    scopus 로고
    • Comparison of outcomes in cancer patients treated within and outside clinical trials: Conceptual framework and structured review
    • DOI 10.1016/S0140-6736(03)15383-4
    • Comparison of outcomes in cancer patients treated within and outside clinical trials: conceptual framework and structured review. Peppercorn JM, Weeks JC, Cook EF, Joffe S, Lancet 2004 363 263 70 10.1016/S0140-6736(03)15383-4 14751698 (Pubitemid 38142408)
    • (2004) Lancet , vol.363 , Issue.9405 , pp. 263-270
    • Peppercorn, J.M.1    Weeks, J.C.2    Cook, E.F.3    Joffe, S.4
  • 61
    • 58949087925 scopus 로고    scopus 로고
    • Therapeutic discourse among nurses and physicians in controlled clinical trials
    • Therapeutic discourse among nurses and physicians in controlled clinical trials. Instone SL, Mueller MR, Gilbert TL, Nurs Ethics 2008 5 6 803 812
    • (2008) Nurs Ethics , vol.5 , Issue.6 , pp. 803-812
    • Instone, S.L.1    Mueller, M.R.2    Gilbert, T.L.3
  • 62
    • 42449147969 scopus 로고    scopus 로고
    • Bench to Bedside. Mapping the Moral Terrain of Clinical Research
    • 10.1353/hcr.2008.0019 19192714
    • Bench to Bedside. Mapping the Moral Terrain of Clinical Research. Joffe S, Miller FG, Hastings Cent Rep 2008 38 2 30 42 10.1353/hcr.2008.0019 19192714
    • (2008) Hastings Cent Rep , vol.38 , Issue.2 , pp. 30-42
    • Joffe, S.1    Miller, F.G.2
  • 63
    • 50949115424 scopus 로고    scopus 로고
    • Children Are Not Just Small Adults: The Urgent Need for High-Quality Trial Evidence in Children
    • 10.1371/journal.pmed.0050172 18700813
    • Children Are Not Just Small Adults: The Urgent Need for High-Quality Trial Evidence in Children. Klassen TP, Hartling L, Craig JC, Offringa M, PLoS Med 2008 5 8 172 10.1371/journal.pmed.0050172 18700813
    • (2008) PLoS Med , vol.5 , Issue.8 , pp. 5172
    • Klassen, T.P.1    Hartling, L.2    Craig, J.C.3    Offringa, M.4
  • 64
    • 26444459415 scopus 로고    scopus 로고
    • Children in reviews: Methodological issues in child-relevant evidence syntheses
    • DOI 10.1186/1471-2431-5-38
    • Children in reviews: methodological issues in child-relevant evidence syntheses. Cramer K, Wiebe N, Moyer V, Hartling L, Williams K, Swingler G, Klassen TP, BMC Pediatr 2005 5 38 10.1186/1471-2431-5-38 16176579 (Pubitemid 41419006)
    • (2005) BMC Pediatrics , vol.5 , pp. 38
    • Cramer, K.1    Wiebe, N.2    Moyer, V.3    Hartling, L.4    Williams, K.5    Swingler, G.6    Klassen, T.P.7
  • 67
    • 0036510899 scopus 로고    scopus 로고
    • Clarifying the ethics of clinical research: A path toward avoiding the therapeutic misconception
    • 12230848
    • Clarifying the ethics of clinical research: a path toward avoiding the therapeutic misconception. Appelbaum PS, Am J Bioeth 2002 2 22 3 12230848
    • (2002) Am J Bioeth , vol.2 , pp. 22-3
    • Appelbaum, P.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.