Evaluation of the Bcl-2 family antagonist ABT-737 in collagen-induced arthritis

Journal of Leukocyte Biology

Volumn 90, Issue 4, 2011, Pages 819-829

  Lawlor, Kate E ^a,c   Smith, Scott D ^a   van Nieuwenhuijze, Annemarie ^a   Huang, David C S ^b,c   Wicks, Ian P ^a,b,d  

^a Reid Rheumatology Laboratory   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Apoptosis; Autoimmunity; Mcl 1; Rheumatoid arthritis

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ANTIBODY; COLLAGEN TYPE 2; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; PROTEIN BCL 2; PROTEIN BCL W; PROTEIN BCL XL; PROTEIN MCL 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; APOPTOSIS; ARTHRITIS; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL SURVIVAL; CELLULAR IMMUNITY; COLLAGEN INDUCED ARTHRITIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; DRUG TARGETING; INFLAMMATORY CELL; LYMPH NODE; LYMPHOCYTE COUNT; LYMPHOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPENIA; MACROPHAGE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; SPLEEN; SYNOVIOCYTE;

ANIMALS; APOPTOSIS; ARTHRITIS, EXPERIMENTAL; BCL-X PROTEIN; BIPHENYL COMPOUNDS; DRUG EVALUATION, PRECLINICAL; LEUKOCYTES; LYMPHOPENIA; MICE; NITROPHENOLS; PIPERAZINES; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SULFONAMIDES; SYNOVIAL MEMBRANE;

MUS;

EID: 80053361349     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0311174     Document Type: Article

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