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Volumn 90, Issue 4, 2011, Pages 741-749

Exchange protein directly activated by cAMP 1 (Epac1) is expressed in human neutrophils and mediates cAMP-dependent activation of the monomeric GTPase Rap1

Author keywords

8CPT 2Me cAMP; Signal transduction

Indexed keywords

8 (4 CHLOROPHENYLTHIO) 2' O METHYLADENOSINE CYCLIC AMP; BETA2 INTEGRIN; CYCLIC AMP; EXCHANGE PROTEIN 1 DIRECTLY ACTIVATED BY CYCLIC AMP; FORSKOLIN; GUANOSINE TRIPHOSPHATASE; MESSENGER RNA; PROTEIN INHIBITOR; RAP1 PROTEIN; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 80053346672     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0211108     Document Type: Article
Times cited : (13)

References (34)
  • 1
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: The leukocyte adhesion cascade updated
    • Ley, K., Laudanna, C., Cybulsky, M. I., Nourshargh, S. (2007) Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 7, 678-689.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 2
    • 0346025501 scopus 로고    scopus 로고
    • Modulation of PMN-endothelial cells interactions by cyclic nucleotides
    • Sato, Y. (2004) Modulation of PMN-endothelial cells interactions by cyclic nucleotides. Curr. Pharm. Des. 10, 163-170.
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 163-170
    • Sato, Y.1
  • 3
    • 0026744834 scopus 로고
    • Association of Rap1 and Rap2 proteins with the specific granules of human neutrophils. Translocation to the plasma membrane during cell activation
    • Maridonneau-Parini, I., De Gunzburg, J. (1992) Association of Rap1 and Rap2 proteins with the specific granules of human neutrophils. Translocation to the plasma membrane during cell activation. J. Biol. Chem. 267, 6396-6402.
    • (1992) J. Biol. Chem. , vol.267 , pp. 6396-6402
    • Maridonneau-Parini, I.1    de Gunzburg, J.2
  • 4
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: Critical elements in the control of small G proteins
    • Bos, J. L., Rehmann, H., Wittinghofer, A. (2007) GEFs and GAPs: critical elements in the control of small G proteins. Cell 129, 865-877.
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 7
    • 0034710567 scopus 로고    scopus 로고
    • The GTPase Rap1 controls functional activation of macrophage integrin αMβ2 by LPS and other inflammatory mediators
    • Caron, E., Self, A. J., Hall, A. (2000) The GTPase Rap1 controls functional activation of macrophage integrin αMβ2 by LPS and other inflammatory mediators. Curr. Biol. 10, 974-978.
    • (2000) Curr. Biol. , vol.10 , pp. 974-978
    • Caron, E.1    Self, A.J.2    Hall, A.3
  • 9
    • 33846849167 scopus 로고    scopus 로고
    • A chemoattractant-mediated Gi-coupled pathway activates adenylyl cyclase in human neutrophils
    • Mahadeo, D. C., Janka-Junttila, M., Smoot, R. L., Roselova, P., Parent, C. A. (2007) A chemoattractant-mediated Gi-coupled pathway activates adenylyl cyclase in human neutrophils. Mol. Biol. Cell 18, 512-522.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 512-522
    • Mahadeo, D.C.1    Janka-Junttila, M.2    Smoot, R.L.3    Roselova, P.4    Parent, C.A.5
  • 11
    • 0018865111 scopus 로고
    • Induction of a transient elevation in intracellular levels of adenosine-3',5'-cyclic monophosphate by chemotactic factors: An early event in human neutrophil activation
    • Simchowitz, L., Fischbein, L. C., Spilberg, I., Atkinson, J. P. (1980) Induction of a transient elevation in intracellular levels of adenosine-3',5'-cyclic monophosphate by chemotactic factors: an early event in human neutrophil activation. J. Immunol. 124, 1482-1491.
    • (1980) J. Immunol. , vol.124 , pp. 1482-1491
    • Simchowitz, L.1    Fischbein, L.C.2    Spilberg, I.3    Atkinson, J.P.4
  • 12
    • 4344588424 scopus 로고    scopus 로고
    • cAMP protects neutrophils against TNF-α-induced apoptosis by activation of cAMP-de-pendent protein kinase, independently of exchange protein directly activated by cAMP (Epac)
    • Krakstad, C., Christensen, A. E., Doskeland, S. O. (2004) cAMP protects neutrophils against TNF-α-induced apoptosis by activation of cAMP-de-pendent protein kinase, independently of exchange protein directly activated by cAMP (Epac). J. Leukoc. Biol. 76, 641-647.
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 641-647
    • Krakstad, C.1    Christensen, A.E.2    Doskeland, S.O.3
  • 13
    • 0035976930 scopus 로고    scopus 로고
    • Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway
    • Martin, M. C., Dransfield, I., Haslett, C., Rossi, A. G. (2001) Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway. J. Biol. Chem. 276, 45041-45050.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45041-45050
    • Martin, M.C.1    Dransfield, I.2    Haslett, C.3    Rossi, A.G.4
  • 15
    • 4344689605 scopus 로고    scopus 로고
    • β-Adrenoceptor stimulation and neutrophil accumulation in mouse airways
    • Miyamoto, M., Tomaki, M., Lötvall, J., Lindén, A. (2004) β-Adrenoceptor stimulation and neutrophil accumulation in mouse airways. Eur. Respir. J.24, 231-237.
    • (2004) Eur. Respir. J , vol.24 , pp. 231-237
    • Miyamoto, M.1    Tomaki, M.2    Lötvall, J.3    Lindén, A.4
  • 16
    • 0036622712 scopus 로고    scopus 로고
    • Protein kinase A regulates β2 integrin avidity in neutrophils
    • Jones, S. L. (2002) Protein kinase A regulates β2 integrin avidity in neutrophils. J. Leukoc. Biol. 71, 1042-1048.
    • (2002) J. Leukoc. Biol. , vol.71 , pp. 1042-1048
    • Jones, S.L.1
  • 17
    • 34548586989 scopus 로고    scopus 로고
    • Role for cAMP-protein kinase A signaling in augmented neutrophil adhesion and chemotaxis in sickle cell disease
    • Canalli, A. A., Franco-Penteado, C. F., Traina, F., Saad, S. T. O., Costa, F. F., Conran, N. (2007) Role for cAMP-protein kinase A signaling in augmented neutrophil adhesion and chemotaxis in sickle cell disease. Eur. J. Haematol. 79, 330-337.
    • (2007) Eur. J. Haematol. , vol.79 , pp. 330-337
    • Canalli, A.A.1    Franco-Penteado, C.F.2    Traina, F.3    Saad, S.T.O.4    Costa, F.F.5    Conran, N.6
  • 18
    • 33845921866 scopus 로고    scopus 로고
    • Nitric oxide produced in response to engagement of 2 integrins on human neutrophils activates the monomeric GTPases Rap1 and Rap2 and promotes adhesion
    • Jenei, V., Deevi, R., Adams, C., Axelsson, L., Hirst, D. G., Andersson, T., Dib, K. (2006) Nitric oxide produced in response to engagement of 2 integrins on human neutrophils activates the monomeric GTPases Rap1 and Rap2 and promotes adhesion. J. Biol. Chem. 281, 35008-35020.
    • (2006) J. Biol. Chem. , vol.281 , pp. 35008-35020
    • Jenei, V.1    Deevi, R.2    Adams, C.3    Axelsson, L.4    Hirst, D.G.5    Andersson, T.6    Dib, K.7
  • 19
    • 0024814732 scopus 로고
    • 2+ binding epitope on leukocyte integrin α subunit
    • 2+ binding epitope on leukocyte integrin α subunit. EMBO J. 8, 3759-3765.
    • (1989) EMBO J , vol.8 , pp. 3759-3765
    • Dransfield, I.1    Hogg, N.2
  • 20
    • 70350051496 scopus 로고    scopus 로고
    • Characterization of degranulation and phagocytic capacity of a human neutrophilic cellular model, PLB-985 cells
    • Pivot-Pajot, C., Chouinard, F. C., Amine El Azreq, M., Harbour, D., Bourgoin, S. G. (2010) Characterization of degranulation and phagocytic capacity of a human neutrophilic cellular model, PLB-985 cells. Immunobiology 215, 38-52.
    • (2010) Immunobiology , vol.215 , pp. 38-52
    • Pivot-Pajot, C.1    Chouinard, F.C.2    Amine El Azreq, M.3    Harbour, D.4    Bourgoin, S.G.5
  • 21
    • 0036105444 scopus 로고    scopus 로고
    • Differentiation of PLB-985 myeloid cells into mature neutrophils, shown by degranulation of terminally differentiated compartments in response to N-formyl peptide and priming of superoxide anion production by granulocyte-macrophage colony-stimulating factor
    • Pedruzzi, E., Fay, M., Elbim, C., Gaudry, M., Gougerot-Pocidalo, M. A. (2002) Differentiation of PLB-985 myeloid cells into mature neutrophils, shown by degranulation of terminally differentiated compartments in response to N-formyl peptide and priming of superoxide anion production by granulocyte-macrophage colony-stimulating factor. Br. J. Haematol. 117, 719-726.
    • (2002) Br. J. Haematol. , vol.117 , pp. 719-726
    • Pedruzzi, E.1    Fay, M.2    Elbim, C.3    Gaudry, M.4    Gougerot-Pocidalo, M.A.5
  • 22
    • 0041836339 scopus 로고    scopus 로고
    • Epac: A new cAMP target and new avenues in cAMP research
    • Bos, J. L. (2003) Epac: a new cAMP target and new avenues in cAMP research. Natl. Rev. Mol. Cell Biol. 4, 733-738.
    • (2003) Natl. Rev. Mol. Cell Biol. , vol.4 , pp. 733-738
    • Bos, J.L.1
  • 23
    • 0029886736 scopus 로고    scopus 로고
    • Identification and characterization of a widely expressed form of adenylyl cyclase
    • Premont, R. T., Matsuoka, I., Mattei, M. G., Pouille, Y., Defer, N., Hanoune, J. (1996) Identification and characterization of a widely expressed form of adenylyl cyclase. J. Biol. Chem. 271, 13900-13907.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13900-13907
    • Premont, R.T.1    Matsuoka, I.2    Mattei, M.G.3    Pouille, Y.4    Defer, N.5    Hanoune, J.6
  • 24
    • 0035958074 scopus 로고    scopus 로고
    • Identification of the binding site for fibrinogen recognitionpeptide γ 383-395 within the α(M)I-domain of integrin α(M)β2
    • Yakubenko, V. P., Solovjov, D. A., Zhang, L., Yee, V. C., Plow, E. F., Ugarova, T. P. (2001) Identification of the binding site for fibrinogen recognitionpeptide γ 383-395 within the α(M)I-domain of integrin α(M)β2. J. Biol. Chem. 276, 13995-14003.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13995-14003
    • Yakubenko, V.P.1    Solovjov, D.A.2    Zhang, L.3    Yee, V.C.4    Plow, E.F.5    Ugarova, T.P.6
  • 25
    • 44349167164 scopus 로고    scopus 로고
    • Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes
    • Petersen, R. K., Madsen, L., Pedersen, L. M., Hallenborg, P., Hagland, H., Viste, K., Doskeland, S. O., Kristiansen, K. (2008) Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes. Mol. Cell. Biol. 28, 3804-3816.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 3804-3816
    • Petersen, R.K.1    Madsen, L.2    Pedersen, L.M.3    Hallenborg, P.4    Hagland, H.5    Viste, K.6    Doskeland, S.O.7    Kristiansen, K.8
  • 26
    • 1642296250 scopus 로고    scopus 로고
    • Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis
    • Tiwari, S., Felekkis, K., Moon, E-Y., Flies, A., Sherr, D. H., Lerner, A. (2004) Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis. Blood 103, 2661-2667.
    • (2004) Blood , vol.103 , pp. 2661-2667
    • Tiwari, S.1    Felekkis, K.2    Moon, E.-Y.3    Flies, A.4    Sherr, D.H.5    Lerner, A.6
  • 28
    • 0019184392 scopus 로고
    • Prevention of degradation of human polymorphonuclear leukocyte proteins by diisopropylfluorophosphate
    • Amrein, P. C., Stossel, T. P. (1980) Prevention of degradation of human polymorphonuclear leukocyte proteins by diisopropylfluorophosphate. Blood 56, 442-447.
    • (1980) Blood , vol.56 , pp. 442-447
    • Amrein, P.C.1    Stossel, T.P.2
  • 29
    • 28644449041 scopus 로고    scopus 로고
    • Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells
    • Kiermayer, S., Biondi, R. M., Imig, J., Plotz, G., Haupenthal, J., Zeuzem, S., Piiper, A. (2005) Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells. Mol. Biol. Cell 16, 5639-5648.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5639-5648
    • Kiermayer, S.1    Biondi, R.M.2    Imig, J.3    Plotz, G.4    Haupenthal, J.5    Zeuzem, S.6    Piiper, A.7
  • 30
    • 23944526384 scopus 로고    scopus 로고
    • Elevation of cyclic AMP in Jurkat T-cells provokes distinct transcriptional responses through the protein kinase A (PKA) and exchange protein activated by cyclic AMP (EPAC) pathways
    • Fuld, S., Borland, G., Yarwood, S. J. (2005) Elevation of cyclic AMP in Jurkat T-cells provokes distinct transcriptional responses through the protein kinase A (PKA) and exchange protein activated by cyclic AMP (EPAC) pathways. Exp. Cell Res. 309, 161-173.
    • (2005) Exp. Cell Res. , vol.309 , pp. 161-173
    • Fuld, S.1    Borland, G.2    Yarwood, S.J.3
  • 32
    • 53449095256 scopus 로고    scopus 로고
    • β 2 integrins target Rap GTPases to the plasma membrane by means of degranulation
    • Dib, K., Axelsson, L., Andersson, T. (2008) β 2 integrins target Rap GTPases to the plasma membrane by means of degranulation. Biochem. Biophys. Res. Commun. 376, 642-646.
    • (2008) Biochem. Biophys. Res. Commun. , vol.376 , pp. 642-646
    • Dib, K.1    Axelsson, L.2    Andersson, T.3
  • 33
    • 66149128873 scopus 로고    scopus 로고
    • The tail of integrins, talin, and kindlins
    • Moser, M., Legate, K. R., Zent, R., Fassler, R. (2009) The tail of integrins, talin, and kindlins. Science 324, 895-899.
    • (2009) Science , vol.324 , pp. 895-899
    • Moser, M.1    Legate, K.R.2    Zent, R.3    Fassler, R.4
  • 34
    • 64149100431 scopus 로고    scopus 로고
    • Riam activates integrins by linking talin to ras GTPase membrane-targeting sequences
    • Lee, H. S., Lim, C. J., Puzon-McLaughlin, W., Shattil, S. J., Ginsberg, M. H. (2009) Riam activates integrins by linking talin to ras GTPase membrane-targeting sequences. J. Biol. Chem. 284, 5119-5127.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5119-5127
    • Lee, H.S.1    Lim, C.J.2    Puzon-McLaughlin, W.3    Shattil, S.J.4    Ginsberg, M.H.5


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