Prostaglandin D 2 induces contractions through activation of TP receptors in peripheral lung tissue from the guinea pig

European Journal of Pharmacology

Volumn 669, Issue 1-3, 2011, Pages 136-142

  Larsson, Anna Karin ^a,b   Hagfjärd, Annika ^a   Dahlén, Sven Erik ^a   Adner, Mikael ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Guinea pig; Lung parenchyma; Ovalbumin; Precision cut lung slice; Prostaglandin D 2; Thromboxane

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; PROSTAGLANDIN D2; PROSTANOID; THROMBOXANE RECEPTOR;

AIRWAY CONSTRICTION; ALLERGIC REACTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FATTY ACID METABOLISM; LUNG PARENCHYMA; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VEIN; RECEPTOR BLOCKING;

ANIMALS; ANTIGENS; GUINEA PIGS; LUNG; MALE; MUSCLE CONTRACTION; OVALBUMIN; PROSTAGLANDIN D2; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PROSTAGLANDIN; RECEPTORS, THROMBOXANE;

EID: 80053337010     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.07.046     Document Type: Article

References (45)

1. H. Abe, T. Takeshita, K. Nagata, T. Arita, Y. Endo, T. Fujita, H. Takayama, M. Kubo, and K. Sugamura Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family Gene 227 1999 71 77 (Pubitemid 29071233)
2. M. Abramovitz, M. Adam, Y. Boie, M. Carriere, D. Denis, C. Godbout, S. Lamontagne, C. Rochette, N. Sawyer, N.M. Tremblay, M. Belley, M. Gallant, C. Dufresne, Y. Gareau, R. Ruel, H. Juteau, M. Labelle, N. Ouimet, and K.M. Metters The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs Biochim. Biophys. Acta 1483 2000 285 293 (Pubitemid 30029060)
3. C.K. Andersson, M. Mori, L. Bjermer, C.G. Lofdahl, and J.S. Erjefalt Novel site-specific mast cell subpopulations in the human lung Thorax 64 2009 297 305
4. S. Balzar, M.L. Fajt, S.A. Comhair, S.C. Erzurum, E. Bleecker, W.W. Busse, M. Castro, B. Gaston, E. Israel, L.B. Schwartz, D. Curran-Everett, C.G. Moore, and S.E. Wenzel Mast cell phenotype, location, and activation in severe asthma: data from the severe asthma research program Am. J. Respir. Crit. Care Med. 183 2011 299 309
5. R.C. Beasley, R.L. Featherstone, M.K. Church, P. Rafferty, J.G. Varley, A. Harris, C. Robinson, and S.T. Holgate Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction J. Appl. Physiol. 66 1989 1685 1693 (Pubitemid 19112975)
6. B.J. Canning, and Y. Chou Using guinea pigs in studies relevant to asthma and COPD Pulm. Pharmacol. Ther. 21 2008 702 720
7. V. Capra, A. Habib, M.R. Accomazzo, S. Ravasi, S. Citro, S. Levy-Toledano, S. Nicosia, and G.E. Rovati Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation Eur. J. Pharmacol. 474 2003 149 159 (Pubitemid 37281443)
8. R.A. Coleman, W.L. Smith, and S. Narumiya International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes Pharmacol. Rev. 46 1994 205 229 (Pubitemid 24185151)
9. S.E. Dahlen, and M. Kumlin Monitoring mast cell activation by prostaglandin D2 in vivo Thorax 59 2004 453 455 (Pubitemid 38797513)
10. W. Dawson, J.R. Boot, A.F. Cockerill, D.N. Mallen, and D.J. Osborne Release of novel prostaglandins and thromboxanes after immunological challenge of guinea pig lung Nature 262 1976 699 702
11. G.P. Dube, D.E. Mais, J.A. Jakubowski, K.A. Brune, B.G. Utterback, T.A. True, L.E. Rinkema, and W.L. Kurtz In vitro characterization of a novel TXA2/PGH2 receptor ligand (S-145) in platelets and vascular and airway smooth muscle J. Pharmacol. Exp. Ther. 262 1992 784 791
12. J.N. Evans, and K.B. Adler The lung strip: evaluation of a method to study contractility of pulmonary parenchyma Exp. Lung Res. 2 1981 187 195 (Pubitemid 11030921)
13. S. Hamid-Bloomfield, A.N. Payne, A.A. Petrovic, and B.J. Whittle The role of prostanoid TP- and DP-receptors in the bronchoconstrictor effect of inhaled PGD2 in anaesthetized guinea-pigs: effect of the DP-antagonist BW A868C Br. J. Pharmacol. 100 1990 761 766 (Pubitemid 20233316)
14. H.D. Held, C. Martin, and S. Uhlig Characterization of airway and vascular responses in murine lungs Br. J. Pharmacol. 126 1999 1191 1199 (Pubitemid 29123755)
15. E.W. Jonsson, and S.E. Dahlen Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma J. Pharmacol. Exp. Ther. 271 1994 615 623 (Pubitemid 24377743)
16. M. Kiriyama, F. Ushikubi, T. Kobayashi, M. Hirata, Y. Sugimoto, and S. Narumiya Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells Br. J. Pharmacol. 122 1997 217 224 (Pubitemid 27397191)
17. J. Komoto, T. Yamada, K. Watanabe, and F. Takusagawa Crystal structure of human prostaglandin F synthase (AKR1C3) Biochemistry 43 2004 2188 2198 (Pubitemid 38279964)
18. A.K. Larsson, M. Back, J. Hjoberg, and S.E. Dahlen Inhibition of nitric-oxide synthase enhances antigen-induced contractions and increases release of cysteinyl-leukotrienes in guinea pig lung parenchyma: nitric oxide as a protective factor J. Pharmacol. Exp. Ther. 315 2005 458 465 (Pubitemid 41380542)
19. A.K. Larsson, F. Fumagalli, A. DiGennaro, M. Andersson, J. Lundberg, C. Edenius, M. Govoni, A. Monopoli, A. Sala, S.E. Dahlen, and G.C. Folco A new class of nitric oxide-releasing derivatives of cetirizine; pharmacological profile in vascular and airway smooth muscle preparations Br. J. Pharmacol. 151 2007 35 44 (Pubitemid 46676009)
20. A.K. Larsson, M. Back, J.O. Lundberg, and S.E. Dahlen Specific mediator inhibition by the NO donors SNP and NCX 2057 in the peripheral lung: implications for allergen-induced bronchoconstriction Respir. Res. 10 2009 46
21. M.C. Liu, W.C. Hubbard, D. Proud, B.A. Stealey, S.J. Galli, A. Kagey-Sobotka, E.R. Bleecker, and L.M. Lichtenstein Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes Am. Rev. Respir. Dis. 144 1991 51 58
22. F. Liu, J.A. Gonzalo, S. Manning, L.E. O'Connell, E.R. Fedyk, K.E. Burke, A.M. Elder, J.C. Pulido, W. Cao, O. Tayber, Y. Qiu, S. Ghosh, T.D. Ocain, M.R. Hodge, and Y. Suzuki-Yagawa Pharmacological characterization of guinea pig chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) Prostaglandins Other Lipid Mediat. 76 2005 133 147 (Pubitemid 40720409)
23. S.J. Lydford, K.C. McKechnie, and P. Leff Interaction of BW A868C, a prostanoid DP-receptor antagonist, with two receptor subtypes in the rabbit isolated saphenous vein Prostaglandins 52 1996 125 139 (Pubitemid 26314923)
24. L. Macchia, M. Hamberg, M. Kumlin, J.H. Butterfield, and J.Z. Haeggstrom Arachidonic acid metabolism in the human mast cell line HMC-1: 5-lipoxygenase gene expression and biosynthesis of thromboxane Biochim. Biophys. Acta 1257 1995 58 74
25. H. Magnussen, S. Boerger, K. Templin, and A.R. Baunack Effects of a thromboxane-receptor antagonist, BAY u 3405, on prostaglandin D2- and exercise-induced bronchoconstriction J. Allergy Clin. Immunol. 89 1992 1119 1126
26. T. Matsuoka, M. Hirata, H. Tanaka, Y. Takahashi, T. Murata, K. Kabashima, Y. Sugimoto, T. Kobayashi, F. Ushikubi, Y. Aze, N. Eguchi, Y. Urade, N. Yoshida, K. Kimura, A. Mizoguchi, Y. Honda, H. Nagai, and S. Narumiya Prostaglandin D2 as a mediator of allergic asthma Science 287 2000 2013 2017
27. M.G. McKenniff, P. Norman, N.J. Cuthbert, and P.J. Gardiner BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro Br. J. Pharmacol. 104 1991 585 590
28. H. Mita, T. Ishii, and K. Akiyama Generation of thromboxane A2 from highly purified human sinus mast cells after immunological stimulation Prostaglandins Leukot. Essent. Fatty Acids 60 1999 175 180 (Pubitemid 29213887)
29. G. Monneret, S. Gravel, M. Diamond, J. Rokach, and W.S. Powell Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor Blood 98 2001 1942 1948
30. X. Norel Prostanoid receptors in the human vascular wall ScientificWorldJournal 7 2007 1359 1374 (Pubitemid 47435435)
31. X. Norel, L. Walch, C. Labat, J.P. Gascard, E. Dulmet, and C. Brink Prostanoid receptors involved in the relaxation of human bronchial preparations Br. J. Pharmacol. 126 1999 867 872 (Pubitemid 29103702)
32. P. Norman, N.J. Cuthbert, M.G. McKenniff, and P.J. Gardiner The thromboxane receptors of rat and guinea-pig lung Eur. J. Pharmacol. 229 1992 171 178 (Pubitemid 23015821)
33. M. Okano, T. Fujiwara, Y. Sugata, D. Gotoh, Y. Masaoka, M. Sogo, W. Tanimoto, M. Yamamoto, R. Matsumoto, N. Eguchi, M. Kiniwa, A.U. Isik, Y. Urade, and K. Nishizaki Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis Am. J. Rhinol. 20 2006 342 348 (Pubitemid 44083419)
34. S. O'Sullivan, B. Dahlen, S.E. Dahlen, and M. Kumlin Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction J. Allergy Clin. Immunol. 98 1996 421 432
35. K. Parameswaran, K. Radford, A. Fanat, J. Stephen, C. Bonnans, B.D. Levy, L.J. Janssen, and P.G. Cox Modulation of human airway smooth muscle migration by lipid mediators and Th-2 cytokines Am. J. Respir. Cell Mol. Biol. 37 2007 240 247 (Pubitemid 47255007)
36. A.R. Ressmeyer, A.K. Larsson, E. Vollmer, S.E. Dahlen, S. Uhlig, and C. Martin Characterisation of guinea pig precision-cut lung slices: comparison with human tissues Eur. Respir. J. 28 2006 603 611 (Pubitemid 44794677)
37. A. Roquet, B. Dahlen, M. Kumlin, E. Ihre, G. Anstren, S. Binks, and S.E. Dahlen Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics Am. J. Respir. Crit. Care Med. 155 1997 1856 1863 (Pubitemid 27256109)
38. H. Sandig, D. Andrew, A.A. Barnes, I. Sabroe, and J. Pease 9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2 FEBS Lett. 580 2006 373 379 (Pubitemid 43089659)
39. E. Selg, L. Lastbom, A. Ryrfeldt, M. Kumlin, and S.E. Dahlen Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung Prostaglandins Leukot. Essent. Fatty Acids 78 2008 89 97 (Pubitemid 351324868)
40. E. Selg, M. Andersson, L. Lastbom, A. Ryrfeldt, and S.E. Dahlen Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites Prostaglandins Other Lipid Mediat. 88 2009 101 110
41. H. Sugimoto, M. Shichijo, M. Okano, and K.B. Bacon CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses Eur. J. Pharmacol. 524 2005 30 37 (Pubitemid 41606809)
42. Y. Urade, and N. Eguchi Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence Prostaglandins Other Lipid Mediat. 68-69 2002 375 382 (Pubitemid 35247408)
43. M. van den Berge, N.H. ten Hacken, J. Cohen, W.R. Douma, and D.S. Postma Small airway disease in asthma and COPD: clinical implications Chest 139 2011 412 423
44. J.R. Vane Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs Nat. New Biol. 231 1971 232 235
45. W.S. Wong, S.L. Bloomquist, A.M. Bendele, and J.H. Fleisch Pharmacological and histological examinations of regional differences of guinea-pig lung: a role of pleural surface smooth muscle in lung strip contraction Br. J. Pharmacol. 105 1992 620 626