A new class of nitric oxide-releasing derivatives of cetirizine; Pharmacological profile in vascular and airway smooth muscle preparations

British Journal of Pharmacology

Volumn 151, Issue 1, 2007, Pages 35-44

  Larsson, A K ^a   Fumagalli, F ^b   DiGennaro, A ^b   Andersson, M ^a   Lundberg, J ^a   Edenius, C ^c   Govoni, M ^a,d   Monopoli, A ^d   Sala, A ^b   Dahlen S E ^a   Folco, G C ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF MILAN   (Italy)

^c Biolipox AB   (Sweden)

^d Nicox Research Institute   (Italy)

Author keywords

Airways; Antihistamine; Cetirizine; NO donors; Ovalbumin; Smooth muscle; Vessel

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 2 (N,N DIMETHYLAMINO)DIAZENOLATE 2 OXIDE; 3 (4 HYDROXY 3 METHOXYPHENYL) 2 PROPENOIC ACID 4 (NITROXY)BUTYL ESTER; 3 (4 HYDROXY 3 METHOXYPHENYL) 2 PROPENOIC ACID 4 BROMOBUTYL ESTER; 3 [4 [2 [4 [(4 CHLOROPHENYL)PHENYLMETHYL] 1 PIPERAZINYL]ETHOXY]ACETYLOXY] 3 METHOXYPHENYL] 2 PROPENOIC ACID 4 (NITROXY)BUTYL ESTER; [2 [4 [(4 CHLOROPHENYL)PHENYLMETHYL] 1 PIPERAZINYL]ETHOXY]ACETIC ACID 4 (NITROXY)BUTYL ESTER; CETIRIZINE; GUANYLATE CYCLASE INHIBITOR; HISTAMINE H1 RECEPTOR ANTAGONIST; NCX 1512; NCX 1514; NCX 2057; NCX 2058; NITRIC OXIDE; NITRIC OXIDE DONOR; OVALBUMIN; OXIDE; UNCLASSIFIED DRUG;

AIRWAY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG RESEARCH; GUINEA PIG; ILEUM; IN VITRO STUDY; LUNG; LUNG PARENCHYMA; MALE; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RABBIT; SMOOTH MUSCLE; TRACHEA; VASCULAR SMOOTH MUSCLE;

ANIMALS; BUTANES; CETIRIZINE; GUINEA PIGS; HISTAMINE ANTAGONISTS; ILEUM; MALE; MUSCLE, SMOOTH; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRO COMPOUNDS; RABBITS; TRACHEA; VASODILATION;

EID: 34247647974     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707214     Document Type: Article

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