Novel electropharmacological activity of amiodarone on human HCN channels heterologously expressed in the Xenopus oocytes

European Journal of Pharmacology

Volumn 669, Issue 1-3, 2011, Pages 15-23

  Fan, Xinrong ^a,b   Chen, Yongjun ^a,b   Wu, Pan ^a,b   Xing, Junlian ^c   Chen, Hui ^a,b   Song, Tao ^a,b   Yang, Jing ^a,b   Zhang, Jun ^a,b   Huang, Congxin ^a,b  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

^c WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Amiodarone; hHCN channel; Voltage clamp; Xenopus oocyte

Indexed keywords

AMIODARONE; COMPLEMENTARY DNA; CYCLIC NUCLEOTIDE GATED CHANNEL; CYCLIC NUCLEOTIDE GATED CHANNEL 1; CYCLIC NUCLEOTIDE GATED CHANNEL 2; CYCLIC NUCLEOTIDE GATED CHANNEL 4; POTASSIUM CHANNEL HERG; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CONCENTRATION RESPONSE; DRUG MECHANISM; DRUG TARGETING; ELECTRIC CURRENT; ELECTRIC POTENTIAL; ENZYME ACTIVATION; HUMAN; HYPERPOLARIZATION; ION CURRENT; OOCYTE; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; XENOPUS;

AMIODARONE; ANIMALS; ANTI-ARRHYTHMIA AGENTS; CELLS, CULTURED; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; FEMALE; GENE EXPRESSION; HUMANS; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; XENOPUS LAEVIS;

EID: 80053316173     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.07.039     Document Type: Article

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