Effect of dronedarone on Na +, Ca 2+ and HCN channels

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 383, Issue 4, 2011, Pages 347-356

  Bogdan, Roman ^a   Goegelein, Heinz ^a   Ruetten, Hartmut ^a  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Action potential clamp; Ca 2+ channels; Dronedarone; hHCN4 channels; Na + channels; Porcine wedge preparations

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; DRONEDARONE; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED ION CHANNEL 4; ION CHANNEL; SODIUM CHANNEL; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY PERFUSION; ARTICLE; CALCIUM CURRENT; CELL ISOLATION; CHO CELL; CONTROLLED STUDY; DRUG EFFECT; EPICARDIUM; FEMALE; GUINEA PIG; HEART LEFT ATRIUM; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART MUSCLE REFRACTORY PERIOD; HEART VENTRICLE; IC 50; MALE; MEMBRANE STEADY POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; SODIUM CURRENT; SWINE;

ACTION POTENTIALS; AMIODARONE; ANIMALS; ANTI-ARRHYTHMIA AGENTS; CALCIUM CHANNELS; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; GUINEA PIGS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MEMBRANE POTENTIALS; MUSCLE PROTEINS; PATCH-CLAMP TECHNIQUES; SODIUM CHANNELS; SWINE;

EID: 79954622483     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-011-0599-9     Document Type: Article

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