High-throughput screen for identifying small molecules that target fungal zinc homeostasis

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Simm, Claudia ^a   Luan, Chi Hao ^a   Weiss, Eric ^a   O'Halloran, Thomas ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; ATOVAQUONE; DISULFIRAM; GREEN FLUORESCENT PROTEIN; HALOFANTRINE; PROTEIN ZRT1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZAP1; UNCLASSIFIED DRUG; ZINC; ZINC TRANSPORTER; CATION TRANSPORT PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; ZAP1 PROTEIN, S CEREVISIAE; ZRT1 PROTEIN, S CEREVISIAE;

ARTICLE; CANDIDA ALBICANS; CELL LEVEL; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG RESEARCH; DRUG TARGETING; FUNGAL METABOLISM; FUNGAL STRAIN; HIGH THROUGHPUT SCREENING; HOMEOSTASIS; METAL METABOLISM; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION; TRANSGENIC ORGANISM; ZINC DEFICIENCY; ZINC HOMEOSTASIS; ZINC METABOLISM; DRUG EFFECT; FLOW CYTOMETRY; GENETICS; METABOLISM;

SACCHAROMYCES CEREVISIAE;

ANTIFUNGAL AGENTS; CATION TRANSPORT PROTEINS; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HOMEOSTASIS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; ZINC;

EID: 80053301897     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025136     Document Type: Article

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