Metallomic analysis of macrophages infected with Histoplasma capsulatum reveals a fundamental role for zinc in host defenses

Journal of Infectious Diseases

Volumn 202, Issue 7, 2010, Pages 1136-1145

  Winters, Michael S ^a   Chan, Qilin ^b   Caruso, Joseph A ^b   Deepe Jr , George S ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; BIOLOGICAL MARKER; CALCIUM ION; CALGRANULIN; COPPER ION; FERRIC ION; FERROUS ION; FERROUS SULFATE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; MAGNESIUM ION; MANGANESE; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; NICKEL; NITRIC OXIDE; PENTETIC ACID; POTASSIUM ION; TRANSFERRIN RECEPTOR; ZINC ION; ZINC SULFATE; CHELATING AGENT; CYTOKINE; IRON; ZINC;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANTIFUNGAL ACTIVITY; ARTICLE; ATOMIC EMISSION SPECTROMETRY; CHELATION; CONTROLLED STUDY; FLOW CYTOMETRY; FUNGUS GROWTH; FUNGUS IMMUNITY; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPLASMA CAPSULATUM; HISTOPLASMOSIS; HOST RESISTANCE; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ZINC METABOLISM; ANIMAL; C57BL MOUSE; CHEMISTRY; HISTOPLASMA; IMMUNOLOGY; MASS SPECTROMETRY; METABOLISM; MICROBIOLOGY;

ANIMALS; CHELATING AGENTS; CYTOKINES; HISTOPLASMA; IRON; MACROPHAGES, PERITONEAL; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; ZINC;

EID: 77956945113     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/656191     Document Type: Article

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