메뉴 건너뛰기




Volumn , Issue JUNE 2011, 2011, Pages

The 5-HT 2A receptor antagonist M100907 produces antiparkinsonian effects and decreases striatal glutamate

Author keywords

Dopamine; Glutamate; M100907; Microdialysis; Motor deficits; MPTP; Parkinsonism; Serotonin

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; GLUTAMIC ACID; SEROTONIN 2A RECEPTOR; VOLINANSERIN;

EID: 80053255279     PISSN: 16625137     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnsys.2011.00048     Document Type: Article
Times cited : (17)

References (50)
  • 1
    • 0031006582 scopus 로고    scopus 로고
    • Serotonin induces excitator postsynaptic potentials in apical den drites of neocortical pyramidal cell
    • Aghajaanian, G. K., and Marek, G. (1997). Serotonin induces excitator postsynaptic potentials in apical den drites of neocortical pyramidal cell. Neuropharmacology 36, 589-599.
    • (1997) Neuropharmacology , vol.36 , pp. 589-599
    • Aghajaanian, G.K.1    Marek, G.2
  • 3
    • 33845430429 scopus 로고    scopus 로고
    • Use of the narrow beam tes in the rat, 6-hydroxydopamine mode of Parkinson's disease
    • Allbutt, H. N., and Henderson, J. M (2007). Use of the narrow beam tes in the rat, 6-hydroxydopamine mode of Parkinson's disease. J. Neurosc Methods 159, 195-202.
    • (2007) J. Neurosc Methods , vol.159 , pp. 195-202
    • Allbutt, H.N.1    Henderson, J.M.2
  • 4
    • 0022922681 scopus 로고
    • Typical an atypical antipsychotic occupancy o D2 and S2 receptors: An autoradio graphic analysis in rat brain
    • Altar, C. A., Wasley, A. M., Neale, R. F and Stone, G. A. (1986). Typical an atypical antipsychotic occupancy o D2 and S2 receptors: an autoradio graphic analysis in rat brain. Brai Res. Bull. 16, 517-525.
    • (1986) Brai Res. Bull , vol.16 , pp. 517-525
    • Altar, C.A.1    Wasley, A.M.2    Neale, R.F.3    Stone, G.A.4
  • 5
    • 0030175903 scopus 로고    scopus 로고
    • Synapti plasticity in the caudate nucleus o patients with Parkinson's disease
    • Anglade, P., Mouatt-Prigent, A., Agid Y., and Hirsch, E. (1996). Synapti plasticity in the caudate nucleus o patients with Parkinson's disease. Neurodegeneration 5, 121-128.
    • (1996) Neurodegeneration , vol.5 , pp. 121-128
    • Anglade, P.1    Mouatt-Prigent, A.2    Agid, Y.3    Hirsch, E.4
  • 6
    • 0018647518 scopus 로고
    • Effect of drugs infuenc ing central serotonergic mechanism on haloperidol-induced catalepsy
    • Balsara, J. J., Jadhav, J. H., and Chandorka A. G. (1979). Effect of drugs infuenc ing central serotonergic mechanism on haloperidol-induced catalepsy. Psychopharmacology (Berl.) 62 67-69.
    • (1979) Psychopharmacology (Berl.) , vol.62 , pp. 67-69
    • Balsara, J.J.1    Jadhav, J.H.2    Chandorka, A.G.3
  • 7
    • 0030299807 scopus 로고    scopus 로고
    • 5-HT1A receptors are no involved in clozapine's lack of catalep togenic potential
    • Bartoszyk, G. D., Roos, C., and Ziegle H. (1996). 5-HT1A receptors are no involved in clozapine's lack of catalep togenic potential. Neuropharmacolog. 35, 1645-1646.
    • (1996) Neuropharmacolog , vol.35 , pp. 1645-1646
    • Bartoszyk, G.D.1    Roos, C.2    Ziegle, H.3
  • 8
    • 0025572228 scopus 로고
    • 5-HT2 antagonist ritanserin in neuroleptic-induced Parkinsonism: A double-blind comparison with orphenadrine and placebo
    • Bersani, G., Grispini, A., Marini, S., Pasini, A., Valducci, M., and Ciani, N. (1990). 5-HT2 antagonist ritanserin in neuroleptic-induced Parkinsonism: a double-blind comparison with orphenadrine and placebo. Clin. Neuropharmacol. 13, 500-506.
    • (1990) Clin. Neuropharmacol , vol.13 , pp. 500-506
    • Bersani, G.1    Grispini, A.2    Marini, S.3    Pasini, A.4    Valducci, M.5    Ciani, N.6
  • 9
    • 23444453520 scopus 로고    scopus 로고
    • 2A but not 5-HT2C receptor antagonism reduces yperlocomotor activity induced in dopamine-depleted rats by striatal administration of the D1 agonist.SKF 82958
    • 2A but not 5-HT2C receptor antagonism reduces yperlocomotor activity induced in dopamine-depleted rats by striatal administration of the D1 agonist.SKF 82958. Neuropharmacology 49, 350-358.
    • (2005) Neuropharmacology , vol.49 , pp. 350-358
    • Bishop, C.1    Daut, G.S.2    Walker, P.D.3
  • 10
    • 0035869746 scopus 로고    scopus 로고
    • Distribution of serotonin 5-HT(2A) receptors in afferents of the rat striatum
    • Bubser, M., Backstrom, J. R., Sanders-Bush, E., Roth, B. L., and Deutch, A. Y. (2001). Distribution of serotonin 5-HT(2A) receptors in afferents of the rat striatum. Synapse 39, 297-304
    • (2001) Synapse , vol.39 , pp. 297-304
    • Bubser, M.1    Backstrom, J.R.2    Sanders-Bush, E.3    Roth, B.L.4    Deutch, A.Y.5
  • 11
    • 0037272827 scopus 로고    scopus 로고
    • Local injec- tions of the 5-hydroxytryptamine antagonist mianserin into substantia. nigra pars reticulata block tremulous jaw movements in rats: Studies with,a putative model of Parkinsonian tremor
    • Carlson, B. B., Wisniecki, A., and Salamone, J. D. (2003). Local injec- tions of the 5-hydroxytryptamine antagonist mianserin into substantia. nigra pars reticulata block tremulous jaw movements in rats: studies with,a putative model of Parkinsonian tremor. Psychopharmacology 165, 229-237.
    • (2003) Psychopharmacology , vol.165 , pp. 229-237
    • Carlson, B.B.1    Wisniecki, A.2    Salamone, J.D.3
  • 12
    • 42449117283 scopus 로고    scopus 로고
    • Metabolic changes detected by proton magnetic reso- nance spectroscopy in vivo and in vitro in a murin model of Parkinson's disease, the MPTP-intoxicated mouse
    • Chassain, C., Bielicki, G., Durand, E., Lolignier, S., Essaf, F., Traore, A., and Durif, F. (2008). Metabolic changes detected by proton magnetic reso- nance spectroscopy in vivo and in vitro in a murin model of Parkinson's disease, the MPTP-intoxicated mouse. J. Neurochem. 105, 874-882.
    • (2008) J. Neurochem , vol.105 , pp. 874-882
    • Chassain, C.1    Bielicki, G.2    Durand, E.3    Lolignier, S.4    Essaf, F.5    Traore, A.6    Durif, F.7
  • 13
    • 0025298139 scopus 로고
    • Primate models of movement disorders of basal ganglia origin
    • DeLong, M. R. (1990). Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 13, 281-285.
    • (1990) Trends Neurosci , vol.13 , pp. 281-285
    • Delong, M.R.1
  • 14
    • 0026567360 scopus 로고
    • Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell
    • Deutch, A. Y., and Cameron, D. S. (1992). Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell. Neuroscience 46, 49-56.
    • (1992) Neuroscience , vol.46 , pp. 49-56
    • Deutch, A.Y.1    Cameron, D.S.2
  • 15
    • 0021981617 scopus 로고
    • Footshock and conditioned stress increase 3,4-dihydroxypheny-lacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra
    • Deutch, A. Y., Tam, S. Y., and Roth, R. H. (1985). Footshock and conditioned stress increase 3,4-dihydroxypheny-lacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra. Brain Res. 333, 143-146.
    • (1985) Brain Res , vol.333 , pp. 143-146
    • Deutch, A.Y.1    Tam, S.Y.2    Roth, R.H.3
  • 16
    • 50649111180 scopus 로고    scopus 로고
    • Serotonin modulation of the basal ganglia circuitry: Therapeutic implication for Parkinson's disease and other motor disorders
    • Di Matteo, V., Pierucci, M., Esposito, E., Crescimanno, G., Benigno, A., and Di Giovanni, G. (2008). Serotonin modulation of the basal ganglia circuitry: therapeutic implication for Parkinson's disease and other motor disorders. Prog. Brain Res. 172, 423-463.
    • (2008) Prog. Brain Res , vol.172 , pp. 423-463
    • di Matteo, V.1    Pierucci, M.2    Esposito, E.3    Crescimanno, G.4    Benigno, A.5    di Giovanni, G.6
  • 17
    • 0034948210 scopus 로고    scopus 로고
    • Evaluation of nigrostriatal dopaminergic function in adult+/+ and +/- BDNF mutant mice
    • Dluzen, D. E., Gao, X., Story, G. M., Anderson, L. I., Kucera, J., and Walro, J. M. (2001). Evaluation of nigrostriatal dopaminergic function in adult+/+ and +/- BDNF mutant mice. Exp. Neurol. 170, 121-128.
    • (2001) Exp. Neurol , vol.170 , pp. 121-128
    • Dluzen, D.E.1    Gao, X.2    Story, G.M.3    Anderson, L.I.4    Kucera, J.5    Walro, J.M.6
  • 18
    • 77953292667 scopus 로고    scopus 로고
    • 2A receptor antagonists improve motor impairments in the MPTP mouse model of Parkinson's disease
    • 2A receptor antagonists improve motor impairments in the MPTP mouse model of Parkinson's disease. Neuropharmacology 59, 31-36.
    • (2010) Neuropharmacology , vol.59 , pp. 31-36
    • Ferguson, M.C.1    Nayyar, T.2    Deutch, A.Y.3    Ansah, T.A.4
  • 19
    • 0346993599 scopus 로고    scopus 로고
    • MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: Reference to striatonigral degeneration
    • Fernagut, P. O., Diguet, E., Bioulac, B., and Tison, F. (2004). MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: reference to striatonigral degeneration. Exp. Neurol. 185, 47-62.
    • (2004) Exp. Neurol , vol.185 , pp. 47-62
    • Fernagut, P.O.1    Diguet, E.2    Bioulac, B.3    Tison, F.4
  • 22
    • 0033037153 scopus 로고    scopus 로고
    • Synergistic interaction between serotonin-2 receptor and dopamine D1 receptor stimulation on striatal preprotachykinin mRNA expression in the 6-hydroxydopamine lesioned rat
    • Gresch, P. J., and Walker, P. D. (1999). Synergistic interaction between serotonin-2 receptor and dopamine D1 receptor stimulation on striatal preprotachykinin mRNA expression in the 6-hydroxydopamine lesioned rat. Brain Res. Mol. Brain Res. 70, 125-134.
    • (1999) Brain Res. Mol. Brain Res , vol.70 , pp. 125-134
    • Gresch, P.J.1    Walker, P.D.2
  • 23
    • 0026958657 scopus 로고
    • Effect of ritanserin, a highly selective 5-HT2 receptor antagonist, on Parkinson's disease
    • Henderson, J., Yiannikas, C., and Graham, J. S. (1992). Effect of ritanserin, a highly selective 5-HT2 receptor antagonist, on Parkinson's disease. Clin. Exp. Neurol. 29, 277-282.
    • (1992) Clin. Exp. Neurol , vol.29 , pp. 277-282
    • Henderson, J.1    Yiannikas, C.2    Graham, J.S.3
  • 25
    • 0025050481 scopus 로고
    • Immunohistochemical study of the serotoninergic innervation of the basal ganglia in the squirrel monkey
    • Lavoie, B., and Parent, A. (1990). Immunohistochemical study of the serotoninergic innervation of the basal ganglia in the squirrel monkey. J. Comp. Neurol. 299, 1-16.
    • (1990) J. Comp. Neurol , vol.299 , pp. 1-16
    • Lavoie, B.1    Parent, A.2
  • 28
    • 0027339712 scopus 로고
    • Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo
    • Matsubara, S., Matsubara, R., Kusumi, I., Koyama, T., and Yamashita, I. (1993). Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo. J. Pharmacol. Exp. Ther. 265, 498-508.
    • (1993) J. Pharmacol. Exp. Ther , vol.265 , pp. 498-508
    • Matsubara, S.1    Matsubara, R.2    Kusumi, I.3    Koyama, T.4    Yamashita, I.5
  • 29
    • 0024854809 scopus 로고
    • The ratios of serotonin2 and dopamine2 affnities differentiate atypical and typical antipsychotic drugs
    • Meltzer, H. Y., Matsubara, S., and Lee, J. C. (1989). The ratios of serotonin2 and dopamine2 affnities differentiate atypical and typical antipsychotic drugs. Psychopharmacol. Bull. 25, 390-392.
    • (1989) Psychopharmacol. Bull , vol.25 , pp. 390-392
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.C.3
  • 30
    • 0032889098 scopus 로고    scopus 로고
    • Time-dependent changes in striatal glutamate synapses following a 6-hydroxydopamine lesion
    • Meshul, C. K., Emre, N., Nakamura, C. M., Allen, C., Donohue, M. K., and Buckman, J. F. (1999). Time-dependent changes in striatal glutamate synapses following a 6-hydroxydopamine lesion. Neuroscience 88, 1-16.
    • (1999) Neuroscience , vol.88 , pp. 1-16
    • Meshul, C.K.1    Emre, N.2    Nakamura, C.M.3    Allen, C.4    Donohue, M.K.5    Buckman, J.F.6
  • 31
    • 0036250065 scopus 로고    scopus 로고
    • Nicotine alters striatal glutamate function and decreases the apomorphine-induced contralateral rotations in 6-OHDA-lesioned rats
    • Meshul, C. K., Kamel, D., Moore, C., Kay, T. S., and Krentz, L. (2002). Nicotine alters striatal glutamate function and decreases the apomorphine-induced contralateral rotations in 6-OHDA-lesioned rats. Exp. Neurol. 175, 257-274.
    • (2002) Exp. Neurol , vol.175 , pp. 257-274
    • Meshul, C.K.1    Kamel, D.2    Moore, C.3    Kay, T.S.4    Krentz, L.5
  • 32
    • 0030662378 scopus 로고    scopus 로고
    • Regional and cellular distribution of serotonin 5-hydroxy-tryptamine2a receptor mRNA in the nucleus accumbens, olfactory tubercle, and caudate putamen of the rat
    • Mijnster, M. J., Raimundo, A. G., Koskuba, K., Klop, H., Docter, G. J., Groenewegen, H. J., and Voorn, P. (1997). Regional and cellular distribution of serotonin 5-hydroxy-tryptamine2a receptor mRNA in the nucleus accumbens, olfactory tubercle, and caudate putamen of the rat. J. Comp. Neurol. 389, 1-11.
    • (1997) J. Comp. Neurol , vol.389 , pp. 1-11
    • Mijnster, M.J.1    Raimundo, A.G.2    Koskuba, K.3    Klop, H.4    Docter, G.J.5    Groenewegen, H.J.6    Voorn, P.7
  • 33
    • 0025001412 scopus 로고
    • Treatment of neuroleptic induced akathisia with the 5-HT2 antagonist ritanserin
    • Miller, C. H., Fleischhacker, W. W., Ehrmann, H., and Kane, J. M. (1990). Treatment of neuroleptic induced akathisia with the 5-HT2 antagonist ritanserin. Psychopharmacol. Bull. 26, 373-376
    • (1990) Psychopharmacol. Bull , vol.16 , pp. 247-251
    • Miller, C.H.1    Fleischhacker, W.W.2    Ehrmann, H.3    Kane, J.M.4
  • 34
    • 0027527435 scopus 로고
    • Serotonergic involvement in haloperidol-induced catalepsy
    • Neal-Beliveau, B. S., Joyce, J. N., and Lucki, I. (1993). Serotonergic involvement in haloperidol-induced catalepsy. J. Pharmacol. Exp. Ther. 265, 207-217.
    • (1993) J. Pharmacol. Exp. Ther , vol.265 , pp. 207-217
    • Neal-Beliveau, B.S.1    Joyce, J.N.2    Lucki, I.3
  • 35
    • 0036460744 scopus 로고    scopus 로고
    • 5-hydroxytryptamine (5-HT, serotonin) and Parkinson's disease - opportunities for novel therapeutics to reduce the problems of levodopa therapy
    • Nicholson, S. L., and Brotchie, J. M. (2002). 5-hydroxytryptamine (5-HT, serotonin) and Parkinson's disease - opportunities for novel therapeutics to reduce the problems of levodopa therapy. Eur. J. Neurol. 9(Suppl. 3), 1-6.
    • (2002) Eur. J. Neurol , vol.9 , Issue.SUPPL. 3 , pp. 1-6
    • Nicholson, S.L.1    Brotchie, J.M.2
  • 36
    • 0027341623 scopus 로고
    • 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone
    • Nyberg, S., Farde, L., Eriksson, L., Halldin, C., and Eriksson, B. (1993). 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl.) 110, 265-272.
    • (1993) Psychopharmacology (Berl.) , vol.110 , pp. 265-272
    • Nyberg, S.1    Farde, L.2    Eriksson, L.3    Halldin, C.4    Eriksson, B.5
  • 39
    • 41549104172 scopus 로고    scopus 로고
    • Differential synaptic plasticity of the corticostri-atal and thalamostriatal systems in an MPTP-treated monkey model of Parkinsonism
    • Raju, D. V., Ahern, T. H., Shah, D. J., Wright, T. M., Standaert, D. G., Hall, R. A., and Smith, Y. (2008). Differential synaptic plasticity of the corticostri-atal and thalamostriatal systems in an MPTP-treated monkey model of Parkinsonism. Eur. J. Neurosci. 27, 1647-1658.
    • (2008) Eur. J. Neurosci , vol.27 , pp. 1647-1658
    • Raju, D.V.1    Ahern, T.H.2    Shah, D.J.3    Wright, T.M.4    Standaert, D.G.5    Hall, R.A.6    Smith, Y.7
  • 40
    • 0037349708 scopus 로고    scopus 로고
    • Acute and subchronic MPTP administration differentially affects striatal glutamate synaptic function
    • Robinson, S., Freeman, P., Moore, C., Touchon, J. C., Krentz, L., and Meshul, C. K. (2003). Acute and subchronic MPTP administration differentially affects striatal glutamate synaptic function. Exp. Neurol. 180, 74-87.
    • (2003) Exp. Neurol , vol.180 , pp. 74-87
    • Robinson, S.1    Freeman, P.2    Moore, C.3    Touchon, J.C.4    Krentz, L.5    Meshul, C.K.6
  • 42
    • 0037630660 scopus 로고    scopus 로고
    • The hallucinogen 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI) increases cortical extracellular glutamate levels in rats
    • Scruggs, J. L., Schmidt, D., and Deutch, A. Y. (2003). The hallucinogen 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI) increases cortical extracellular glutamate levels in rats. Neurosci. Lett. 346, 137-140.
    • (2003) Neurosci. Lett , vol.346 , pp. 137-140
    • Scruggs, J.L.1    Schmidt, D.2    Deutch, A.Y.3
  • 43
    • 33749024759 scopus 로고    scopus 로고
    • Evaluation of the integrity of the dopamine system in a rodent model of Parkinson's disease: Small animal positron emission tomography compared to behavioral assessment and autoradiography
    • Strome, E. M., Cepeda, I. L., Sossi, V., and Doudet, D. J. (2006). Evaluation of the integrity of the dopamine system in a rodent model of Parkinson's disease: small animal positron emission tomography compared to behavioral assessment and autoradiography. Mol. Imaging Biol. 8, 292-299.
    • (2006) Mol. Imaging Biol , vol.8 , pp. 292-299
    • Strome, E.M.1    Cepeda, I.L.2    Sossi, V.3    Doudet, D.J.4
  • 44
    • 0036447089 scopus 로고    scopus 로고
    • Detection of behavioral impairments correlated to neurochemical defcits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Tillerson, J. L., Caudle, W. M., Reveron, M. E., and Miller, G. W. (2002). Detection of behavioral impairments correlated to neurochemical defcits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Exp. Neurol. 178, 80-90.
    • (2002) Exp. Neurol , vol.178 , pp. 80-90
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 45
    • 0037445497 scopus 로고    scopus 로고
    • Grid performance test to measure behavioral impairment in the MPTP-treated-mouse model of Parkinsonism
    • Tillerson, J. L., and Miller, G. W. (2003). Grid performance test to measure behavioral impairment in the MPTP-treated-mouse model of Parkinsonism. J. Neurosci. Methods 123, 189-200.
    • (2003) J. Neurosci. Methods , vol.123 , pp. 189-200
    • Tillerson, J.L.1    Miller, G.W.2
  • 46
    • 33845728900 scopus 로고    scopus 로고
    • Environmental enrichment brings a beneficial effect on beam walking and enhances the migration of doublecortin-positive cells following striatal lesions in rats
    • Urakawa, S., Hida, H., Masuda, T., Misumi, S., Kim, T. S., and Nishino, H. (2007). Environmental enrichment brings a beneficial effect on beam walking and enhances the migration of doublecortin-positive cells following striatal lesions in rats. Neuroscience 144, 920-933.
    • (2007) Neuroscience , vol.144 , pp. 920-933
    • Urakawa, S.1    Hida, H.2    Masuda, T.3    Misumi, S.4    Kim, T.S.5    Nishino, H.6
  • 49
    • 0030018405 scopus 로고    scopus 로고
    • 2A, 5-HT2C, and 5-HT6 with neuropeptides in rat striatum
    • 2A, 5-HT2C, and 5-HT6 with neuropeptides in rat striatum. J. Comp. Neurol. 370, 405-414.
    • (1996) J. Comp. Neurol , vol.370 , pp. 405-414
    • Ward, R.P.1    Dorsa, D.M.2
  • 50
    • 0033060133 scopus 로고    scopus 로고
    • Clozapine pretreatment modifes haloperidol-elicited forebrain Fos induction: A regionally-specifc double dissociation
    • Young, C. D., Bubser, M., Meltzer, H. Y., and Deutch, A. Y. (1999). Clozapine pretreatment modifes haloperidol-elicited forebrain Fos induction: a regionally-specifc double dissociation. Psychopharmacology (Berl.) 144, 255-263.
    • (1999) Psychopharmacology (Berl.) , vol.144 , pp. 255-263
    • Young, C.D.1    Bubser, M.2    Meltzer, H.Y.3    Deutch, A.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.