Central role of PKCα in isoenzyme-selective regulation of cardiac transient outward current I to and Kv4.3 channels

Journal of Molecular and Cellular Cardiology

Volumn 51, Issue 5, 2011, Pages 722-729

  Scholz, E P ^a   Welke, F ^a   Joss, N ^a   Seyler, C ^a   Zhang, W ^b   Scherer, D ^a   Volkers M ^a   Bloehs, R ^a   Thomas, D ^a   Katus, H A ^a   Karle, C A ^a   Zitron, E ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b Renal Center Heidelberg   (Germany)

Author keywords

Adrenergic regulation; I to; Isoenzymes; Kv4.3; PKC; PKC ; Protein kinase C; Repolarization; Transient outward current

Indexed keywords

ISOENZYME; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV4.3; PROTEIN KINASE C ALPHA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; XENOPUS;

ANIMALS; CARBAZOLES; ENZYME INHIBITORS; FEMALE; ISOENZYMES; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; OOCYTES; PATCH-CLAMP TECHNIQUES; PLASMIDS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; RATS; RECOMBINANT PROTEINS; SHAL POTASSIUM CHANNELS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TETRADECANOYLPHORBOL ACETATE; TRANSFECTION; XENOPUS;

RATTUS;

EID: 80053248083     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.07.012     Document Type: Article

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