Specific and nonspecific effects of protein kinase C on the epithelial Na+ channel

Journal of General Physiology

Volumn 115, Issue 5, 2000, Pages 559-570

  Awayda, Mouhamed S ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epithelial Na+ channel; Impedance analysis; Protein kinase C; Trafficking; Xenopus oocytes

Indexed keywords

AMILORIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; SODIUM CHANNEL; SODIUM ION;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; IMPEDANCE; MEMBRANE CHANNEL; NONHUMAN; OOCYTE; VOLTAGE CLAMP; XENOPUS;

AMILORIDE; ANIMALS; BIOLOGICAL TRANSPORT; CARCINOGENS; DIURETICS; ELECTRIC CONDUCTIVITY; ELECTRIC IMPEDANCE; EPITHELIAL SODIUM CHANNEL; HUMANS; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; SODIUM CHANNELS; TETRADECANOYLPHORBOL ACETATE; XENOPUS;

EID: 0034117273     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.115.5.559     Document Type: Article

References (28)

1. Aballay, A., P.D. Stahl, and L.S. Mayorga. 1999. Phorbol ester promotes endocytosis by inactivating a factor involved in endosome fusion. J. Cell Sci. 112:2549-2557.
2. 2. Am. J. Physiol. Renal Physiol. 272:F624-F631.
3. + channel. J. Gen. Physiol. 108:49-65.
4. + channel by membrane tension. J. Gen. Physiol. 112: 97-111.
5. Awayda, M.S., W. Van Driessche, and S.I. Helman. 1999. Frequency-dependent capacitance of the apical membrane of frog skin: dielectric relaxation processes. Biophys. J. 76:219-232.
6. + channels. J. Membr. Biol. 143:1-19.
7. Beron, J., I. Forster, P. Beguin, K. Geering, and F. Verrey. 1997. Phorbol 12-myristate 13-acetate down-regulates Na,K-ATPase independent of its protein kinase C site: decrease in basolateral cell surface area. Mol. Biol. Cell. 8:387-398.
8. Chou, C.-L., S.I. Rapko, and M.A. Knepper. 1998. Phosphoinositide signaling in the rat inner medullary collecting duct. Am. J. Physiol. Renal Physiol. 274:F564-F572.
9. + permeability. J. Membr. Biol. 97:193-204.
10. Clausen, C., S.A. Lewis, and J.M. Diamond. 1979. Impedance analysis of a tight epithelium using a distributed resistance model. Biophys. J. 26:291-318.
11. Cole, K.S. 1968. Membranes, Ions and Impulses. University of California Press, Berkeley, CA. 569 pp.
12. + absorption in rabbit cortical collecting duct. J. Clin. Invest. 95:2749-2756.
13. Diamond, J.M., and T.E. Machen. 1983. Impedance analysis in epithelia and the problem of gastric acid secretion. J. Membr. Biol. 72:17-41.
14. Eaton, D.C., A. Becchetti, H. Ma, and B.N. Ling. 1995. Renal sodium channels: regulation and single channel properties. Kidney. Int. 48:941-949.
15. Els, W.J., X. Liu, and S.I. Helman. 1998. Differential effects of phorbol ester (PMA) on blocker-sensitive ENaCs of frog skin and A6 epithelia. Am. J. Physiol. Cell Physiol. 275:C120-C129.
16. Garty, H., and L.G. Palmer. 1997. Epithelial sodium channels: functions, structure, and regulation. Physiol. Rev. 77:359-396.
17. Hanks, S.K., and T. Hunter. 1995. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9:576-596.
18. + channels in A6 cells, a regulatory role for protein kinase C. Am. J. Physiol. Renal Physiol. 256:F1094-F2003.
19. + transport by atriopeptin, protein kinase C, and pertussis toxin. Am. J. Physiol. 253:F372-F376.
20. + channels in planar lipid bilayers. Am. J. Physiol. Cell Physiol. 265:C85-C91.
21. Palmer, L.G. 1992. Epithelial Na channels: function and diversity. Annu. Rev. Physiol. 54:51-66.
22. Palmer, L.G., and G. Frindt. 1996. Gating of Na channels in the rat cortical collecting tubule: effects of voltage and membrane stretch. J. Gen. Physiol. 107:35-45.
23. + and water transport in the rat CCD. Am. J. Physiol. Renal Physiol. 265:F569-F577.
24. Rosson, D., T.G. O'Brien, J.A. Kampherstein, Z. Szallasi, K. Bogi, P.M. Blumberg, and J.M. Mullin. 1997. Protein kinase C-alpha activity modulates transepithelial permeability and cell junctions in the LLC-PK1 epithelial cell line. J. Biol. Chem. 272:14950-14953.
25. Silver, R.B., G. Frindt, E.E. Windhager, and L.G. Palmer. 1993. Feedback regulation of Na channels in rat CCT. I. Effects of inhibition of the Na pump. Am. J. Physiol. Renal Physiol. 264:F557-F564.
26. Shimkets, R.A., R. Lifton, and C.M. Canessa. 1998. In vivo phosphorylation of the epithelial sodium channel. Proc. Natl. Acad. Sci. USA. 95:3301-3305.
27. Weber, W.-M., H. Cuppens, J.J. Gassiman, W. Clauss, and W. Van Driessche. 1999. Capacitance measurements reveal different pathways for the activation of CFTR. Pflügers Arch. 438:561-569.
28. Wilborn, T.W., and J.A. Schafer. 1996. Differential expression of PKC isoforms in fresh and cultured rabbit CCD. Am. J. Physiol. Renal Physiol. 270:F766-F775.