-
1
-
-
0033520092
-
Chronic myelogenous leukemia: biology and therapy
-
Faderl S, Talpaz M, Estrov Z, et al Chronic myelogenous leukemia: biology and therapy. Ann Intern Med. 1999; 131: 207-19.
-
(1999)
Ann Intern Med.
, vol.131
, pp. 207-219
-
-
Faderl, S.1
Talpaz, M.2
Estrov, Z.3
-
2
-
-
0033614446
-
Chronic myeloid leukemia
-
Sawyers CL. Chronic myeloid leukemia. N Engl J Med. 1999; 340: 1330-40.
-
(1999)
N Engl J Med.
, vol.340
, pp. 1330-1340
-
-
Sawyers, C.L.1
-
3
-
-
0025117392
-
Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
-
Daley GQ, Van Etten RA, Baltimore D. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science. 1990; 247: 824-30.
-
(1990)
Science.
, vol.247
, pp. 824-830
-
-
Daley, G.Q.1
Van Etten, R.A.2
Baltimore, D.3
-
4
-
-
0025187837
-
Induction of a chronic myelogenous leukemia -like syndrome in mice with v-abl and BCR/ABL
-
Kelliher MA, McLaughlin J, Witte ON, et al Induction of a chronic myelogenous leukemia -like syndrome in mice with v-abl and BCR/ABL. Proc Natl Acad Sci USA. 1990;87: 6649-53.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6649-6653
-
-
Kelliher, M.A.1
McLaughlin, J.2
Witte, O.N.3
-
5
-
-
0025209916
-
Acute leukaemia in bcr/abl transgenic mice
-
Heisterkamp N, Jenster G, ten Hoeve J, et al Acute leukaemia in bcr/abl transgenic mice. Nature. 1990;344: 251-3.
-
(1990)
Nature.
, vol.344
, pp. 251-253
-
-
Heisterkamp, N.1
Jenster, G.2
ten Hoeve, J.3
-
6
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
-
Lugo TG, Pendergast AM, Muller AJ, et al Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science. 1990; 247: 1079-82.
-
(1990)
Science.
, vol.247
, pp. 1079-1082
-
-
Lugo, T.G.1
Pendergast, A.M.2
Muller, A.J.3
-
7
-
-
85014301696
-
Bcr-abl-positive cells secrete angiogenic factors including matrix metalloproteinases and stimulate angiogenesis in vivo in Matrigel implants
-
Janowska-Wieczorek A, Majka M, Marquez-Curtis L, et al Bcr-abl-positive cells secrete angiogenic factors including matrix metalloproteinases and stimulate angiogenesis in vivo in Matrigel implants. Leukemia. 2002; 16: 1160-6.
-
(2002)
Leukemia.
, vol.16
, pp. 1160-1166
-
-
Janowska-Wieczorek, A.1
Majka, M.2
Marquez-Curtis, L.3
-
8
-
-
43749089135
-
MT1-MMP as a downstream target of BCR-ABL/ABL interactor 1 signaling: polarized distribution and involvement in BCR-ABL-stimulated leukemic cell migration
-
Sun X, Li Y, Yu W, et al MT1-MMP as a downstream target of BCR-ABL/ABL interactor 1 signaling: polarized distribution and involvement in BCR-ABL-stimulated leukemic cell migration. Leukemia. 2008; 22: 1053-6.
-
(2008)
Leukemia.
, vol.22
, pp. 1053-1056
-
-
Sun, X.1
Li, Y.2
Yu, W.3
-
10
-
-
77949656494
-
Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis
-
Dennemärker J, Lohmüller T, Mayerle J, et al Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis. Oncogene. 2010; 29: 1611-21.
-
(2010)
Oncogene.
, vol.29
, pp. 1611-1621
-
-
Dennemärker, J.1
Lohmüller, T.2
Mayerle, J.3
-
11
-
-
33846643454
-
Cysteine cathepsins and the cutting edge of cancer invasion
-
Gocheva V, Joyce JA. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle. 2007; 6: 60-4.
-
(2007)
Cell Cycle.
, vol.6
, pp. 60-64
-
-
Gocheva, V.1
Joyce, J.A.2
-
12
-
-
75549088309
-
Cathepsin L, target in cancer treatment
-
Lankelma JM, Voorend DM, Barwari T, et al Cathepsin L, target in cancer treatment? Life Sci. 2010; 86: 225-33.
-
(2010)
Life Sci.
, vol.86
, pp. 225-233
-
-
Lankelma, J.M.1
Voorend, D.M.2
Barwari, T.3
-
13
-
-
0035132101
-
Interleukin-6 and transforming growth factor-beta 1 control expression of cathepsins B and L in human lung epithelial cells
-
Gerber A, Wille a, Welte T, et al Interleukin-6 and transforming growth factor-beta 1 control expression of cathepsins B and L in human lung epithelial cells. J Interferon Cytokine Res. 2001; 21: 11-9.
-
(2001)
J Interferon Cytokine Res.
, vol.21
, pp. 11-19
-
-
Gerber, A.1
Wille, A.2
Welte, T.3
-
14
-
-
0034837026
-
Cathepsins are upregulated by IFN-gamma/STAT1 in human muscle culture: a possible active factor in dermatomyositis
-
Gallardo E, de Andres I, Illa I. Cathepsins are upregulated by IFN-gamma/STAT1 in human muscle culture: a possible active factor in dermatomyositis. J Neuropathol Exp Neurol. 2001; 60: 847-55.
-
(2001)
J Neuropathol Exp Neurol.
, vol.60
, pp. 847-855
-
-
Gallardo, E.1
de Andres, I.2
Illa, I.3
-
15
-
-
4544286160
-
Enhanced cathepsin L expression is mediated by different Ras effector pathways in fibroblasts and epithelial cells
-
Collette J, Ulku AS, Der CJ, et al Enhanced cathepsin L expression is mediated by different Ras effector pathways in fibroblasts and epithelial cells. Int J Cancer. 2004; 112: 190-9.
-
(2004)
Int J Cancer.
, vol.112
, pp. 190-199
-
-
Collette, J.1
Ulku, A.S.2
Der, C.J.3
-
16
-
-
0031874052
-
Presence of activated ras correlates with increased cysteine proteinase activities in human colorectal carcinomas
-
Kim K, Cai J, Shuja S, et al Presence of activated ras correlates with increased cysteine proteinase activities in human colorectal carcinomas. Int J Cancer. 1998; 79: 324-33.
-
(1998)
Int J Cancer.
, vol.79
, pp. 324-333
-
-
Kim, K.1
Cai, J.2
Shuja, S.3
-
17
-
-
0018866673
-
Tumor promoters and Kirsten sarcoma virus increase synthesis of a secreted glycoprotein by regulating levels of translatable mRNA
-
Gottesman MM, Sobel ME. Tumor promoters and Kirsten sarcoma virus increase synthesis of a secreted glycoprotein by regulating levels of translatable mRNA. Cell. 1980; 19: 449-55.
-
(1980)
Cell.
, vol.19
, pp. 449-455
-
-
Gottesman, M.M.1
Sobel, M.E.2
-
18
-
-
34547691352
-
Transcriptional upregulation of human cathepsin L by VEGF in glioblastoma cells
-
Keerthivasan S, Keerthivasan G, Mittal S, et al Transcriptional upregulation of human cathepsin L by VEGF in glioblastoma cells. Gene. 2007; 399: 129-36.
-
(2007)
Gene.
, vol.399
, pp. 129-136
-
-
Keerthivasan, S.1
Keerthivasan, G.2
Mittal, S.3
-
19
-
-
0032499627
-
Involvement of carboxy-terminal amino acids in secretion of human lysosomal protease cathepsin L
-
Chauhan SS, Ray D, Kane SE, et al Involvement of carboxy-terminal amino acids in secretion of human lysosomal protease cathepsin L. Biochemistry. 1998; 37: 8584-94.
-
(1998)
Biochemistry.
, vol.37
, pp. 8584-8594
-
-
Chauhan, S.S.1
Ray, D.2
Kane, S.E.3
-
20
-
-
18744390846
-
Cathepsins B and L and their inhibitors stefin B and cystatin C as markers for malignant progression of benign meningiomas
-
Trinkaus M, Vranic A, Dolenc VV, et al Cathepsins B and L and their inhibitors stefin B and cystatin C as markers for malignant progression of benign meningiomas. Int J Biol Markers. 2005; 20: 50-9.
-
(2005)
Int J Biol Markers.
, vol.20
, pp. 50-59
-
-
Trinkaus, M.1
Vranic, A.2
Dolenc, V.V.3
-
21
-
-
0043125549
-
Expression, proliferation activity and clinical significance of cathepsin B and cathepsin L in operated lung cancer
-
Kayser K, Richter N, Hufnagl P, et al Expression, proliferation activity and clinical significance of cathepsin B and cathepsin L in operated lung cancer. Anticancer Res. 2003; 23: 2767-72.
-
(2003)
Anticancer Res.
, vol.23
, pp. 2767-2772
-
-
Kayser, K.1
Richter, N.2
Hufnagl, P.3
-
22
-
-
0031887693
-
Prognostic significance of cathepsins B and L in primary human breast cancer
-
Foekens JA, Kos J, Peters HA, et al Prognostic significance of cathepsins B and L in primary human breast cancer. J Clin Oncol. 1998; 16: 1013-21.
-
(1998)
J Clin Oncol.
, vol.16
, pp. 1013-1021
-
-
Foekens, J.A.1
Kos, J.2
Peters, H.A.3
-
23
-
-
4644236863
-
Prognostic impact of cysteine proteases cathepsin B and cathepsin L in pancreatic adenocarcinoma
-
Niedergethmann M, Wostbrock B, Sturm JW, et al Prognostic impact of cysteine proteases cathepsin B and cathepsin L in pancreatic adenocarcinoma. Pancreas. 2004; 29: 204-11.
-
(2004)
Pancreas.
, vol.29
, pp. 204-211
-
-
Niedergethmann, M.1
Wostbrock, B.2
Sturm, J.W.3
-
24
-
-
0027392688
-
Cloning, genomic organization, and chromosomal localization of human cathepsin L
-
Chauhan SS, Popescu NC, Ray D, et al Cloning, genomic organization, and chromosomal localization of human cathepsin L. J Biol Chem. 1993; 268: 1039-45.
-
(1993)
J Biol Chem.
, vol.268
, pp. 1039-1045
-
-
Chauhan, S.S.1
Popescu, N.C.2
Ray, D.3
-
25
-
-
0037178279
-
Identification and characterization of a novel human cathepsin L splice variant
-
Arora S, Chauhan SS. Identification and characterization of a novel human cathepsin L splice variant. Gene. 2002; 293: 123-31.
-
(2002)
Gene.
, vol.293
, pp. 123-131
-
-
Arora, S.1
Chauhan, S.S.2
-
26
-
-
0037377077
-
Genomic deletions on other chromosomes involved in variant t(9;22) chronic myeloid leukemia cases
-
Albano F, Specchia G, Anelli L, et al Genomic deletions on other chromosomes involved in variant t(9;22) chronic myeloid leukemia cases. Genes Chromosomes Cancer. 2003; 36: 353-60.
-
(2003)
Genes Chromosomes Cancer.
, vol.36
, pp. 353-360
-
-
Albano, F.1
Specchia, G.2
Anelli, L.3
-
27
-
-
0016640079
-
Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome
-
Lozzio CB, Lozzio BB. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood. 1975; 45: 321-34.
-
(1975)
Blood.
, vol.45
, pp. 321-334
-
-
Lozzio, C.B.1
Lozzio, B.B.2
-
28
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976; 72: 248-54.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
29
-
-
0036363166
-
Differential activity of cathepsin L in human placenta at two different stages of gestation
-
Divya, Chhikara P, Mahajan VS, et al Differential activity of cathepsin L in human placenta at two different stages of gestation. Placenta. 2002; 23: 59-64.
-
(2002)
Placenta.
, vol.23
, pp. 59-64
-
-
Chhikara, P.1
Mahajan, V.S.2
-
30
-
-
17344392308
-
A new mathematical model for relative quantification in real- time RT-PCR
-
Pfaffl, MW. A new mathematical model for relative quantification in real- time RT-PCR. Nucleic Acids Res. 2001; 29: 2002-7.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2002-2007
-
-
Pfaffl, M.W.1
-
31
-
-
33644833718
-
Expression of cathepsin L in human tumor cells is under the control of distinct regulatory mechanisms
-
Jean D, Rousselet N, Frade R. Expression of cathepsin L in human tumor cells is under the control of distinct regulatory mechanisms. Oncogene. 2006; 25: 1474-84.
-
(2006)
Oncogene.
, vol.25
, pp. 1474-1484
-
-
Jean, D.1
Rousselet, N.2
Frade, R.3
-
32
-
-
48449091213
-
The proto-oncogene expression varies over the course of chronic myeloid leukemia
-
Vidovic A, Jankovic G, Colovic M, et al The proto-oncogene expression varies over the course of chronic myeloid leukemia. Hematology. 2008; 13: 34-40.
-
(2008)
Hematology.
, vol.13
, pp. 34-40
-
-
Vidovic, A.1
Jankovic, G.2
Colovic, M.3
-
33
-
-
20844440739
-
Identification of genes potentially involved in disease transformation of CML
-
Janssen JJ, Klaver SM, Waisfisz Q, et al Identification of genes potentially involved in disease transformation of CML. Leukemia. 2005; 19: 998-1004.
-
(2005)
Leukemia.
, vol.19
, pp. 998-1004
-
-
Janssen, J.J.1
Klaver, S.M.2
Waisfisz, Q.3
-
34
-
-
0346122778
-
Inhibition of K562 leukemia angiogenesis and growth by expression of antisense vascular endothelial growth factor (VEGF) sequence
-
He R, Liu B, Yang C, et al Inhibition of K562 leukemia angiogenesis and growth by expression of antisense vascular endothelial growth factor (VEGF) sequence. Cancer Gene Ther. 2003; 10: 879-86.
-
(2003)
Cancer Gene Ther.
, vol.10
, pp. 879-886
-
-
He, R.1
Liu, B.2
Yang, C.3
-
35
-
-
0036181041
-
Soluble angiogenic factors: implications for chronic myeloproliferative disorders
-
Musolino C, Calabro L, Bellomo G, et al Soluble angiogenic factors: implications for chronic myeloproliferative disorders. Am J Hematol. 2002; 69: 159-63.
-
(2002)
Am J Hematol.
, vol.69
, pp. 159-163
-
-
Musolino, C.1
Calabro, L.2
Bellomo, G.3
-
36
-
-
0037111665
-
BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin
-
Mayerhofer M, Valent P, Sperr WR, et al BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin. Blood. 2002; 100: 3767-75.
-
(2002)
Blood.
, vol.100
, pp. 3767-3775
-
-
Mayerhofer, M.1
Valent, P.2
Sperr, W.R.3
-
37
-
-
12144287119
-
Immunohistochemical detection of VEGF in the bone marrow of patients with chronic myeloid leukemia and correlation with the phase of disease
-
Krauth MT, Simonitsch I, Aichberger KJ, et al Immunohistochemical detection of VEGF in the bone marrow of patients with chronic myeloid leukemia and correlation with the phase of disease. Am J Clin Pathol. 2004; 121: 473-81.
-
(2004)
Am J Clin Pathol.
, vol.121
, pp. 473-481
-
-
Krauth, M.T.1
Simonitsch, I.2
Aichberger, K.J.3
-
38
-
-
0022350512
-
Genealogy of mammalian cysteine proteinase inhibitors. Common evolutionary origin of stefins, cystatins and kininogens
-
Muller-Esterl W, Fritz H, Kellermann J, et al Genealogy of mammalian cysteine proteinase inhibitors. Common evolutionary origin of stefins, cystatins and kininogens. FEBS Lett. 1985; 191: 221-6.
-
(1985)
FEBS Lett.
, vol.191
, pp. 221-226
-
-
Muller-Esterl, W.1
Fritz, H.2
Kellermann, J.3
-
39
-
-
0037069925
-
Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells
-
Konduri SD, Yanamandra N, Siddique K, et al Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells. Oncogene. 2002; 21: 8705-12.
-
(2002)
Oncogene.
, vol.21
, pp. 8705-8712
-
-
Konduri, S.D.1
Yanamandra, N.2
Siddique, K.3
-
40
-
-
13544276456
-
Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells - a preliminary study
-
Vigneswaran N, Wu J, Muller S, et al Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells - a preliminary study. Pathol Res Pract. 2005; 200: 753-62.
-
(2005)
Pathol Res Pract.
, vol.200
, pp. 753-762
-
-
Vigneswaran, N.1
Wu, J.2
Muller, S.3
-
41
-
-
34548249665
-
Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions
-
Rivenbark AG, Livasy CA, Boyd CE, et al Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions. Exp Mol Pathol. 2007; 8: 188-97.
-
(2007)
Exp Mol Pathol.
, vol.8
, pp. 188-197
-
-
Rivenbark, A.G.1
Livasy, C.A.2
Boyd, C.E.3
-
42
-
-
0042674172
-
Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma
-
Sato N, Maitra A, Fukushima N, et al Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. Cancer Res. 2003; 63: 4158-66.
-
(2003)
Cancer Res.
, vol.63
, pp. 4158-4166
-
-
Sato, N.1
Maitra, A.2
Fukushima, N.3
-
43
-
-
0026712439
-
5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression
-
Shin TH, Paterson AJ, Grant JH 3rd, et al 5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression. Mol Cell Biol. 1992; 12: 3998-4006.
-
(1992)
Mol Cell Biol.
, vol.12
, pp. 3998-4006
-
-
Shin, T.H.1
Paterson, A.J.2
Grant 3rd, J.H.3
-
44
-
-
41649107484
-
5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene
-
Hagiwara H, Sato H, Ohde Y, et al 5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene. Br J Pharmacol. 2008; 153: 1373-81.
-
(2008)
Br J Pharmacol.
, vol.153
, pp. 1373-1381
-
-
Hagiwara, H.1
Sato, H.2
Ohde, Y.3
-
45
-
-
0034665786
-
Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes
-
Aguayo A, Kantarjian H, Manshouri T, et al Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood. 2000; 96: 2240-5.
-
(2000)
Blood.
, vol.96
, pp. 2240-2245
-
-
Aguayo, A.1
Kantarjian, H.2
Manshouri, T.3
-
46
-
-
0035706649
-
Angiogenesis in chronic myeloproliferative diseases
-
Di Raimondo F, Palumbo GA, Molica S, et al Angiogenesis in chronic myeloproliferative diseases. Acta Haematol. 2001; 106: 177-83.
-
(2001)
Acta Haematol.
, vol.106
, pp. 177-183
-
-
Di Raimondo, F.1
Palumbo, G.A.2
Molica, S.3
-
47
-
-
0037269498
-
Clinicopathologic correlations of bone marrow angiogenesis in chronic myeloid leukemia: a morphometric study
-
Korkolopoulou P, Viniou N, Kavantzas N, et al Clinicopathologic correlations of bone marrow angiogenesis in chronic myeloid leukemia: a morphometric study. Leukemia. 2003; 17: 89-97.
-
(2003)
Leukemia.
, vol.17
, pp. 89-97
-
-
Korkolopoulou, P.1
Viniou, N.2
Kavantzas, N.3
-
48
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet P. Angiogenesis in health and disease. Nat Med. 2003; 9: 653-60.
-
(2003)
Nat Med.
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
49
-
-
0037805549
-
Basement membranes: structure, assembly and role in tumour angiogenesis
-
Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer. 2003; 3: 422-33.
-
(2003)
Nat Rev Cancer.
, vol.3
, pp. 422-433
-
-
Kalluri, R.1
-
50
-
-
0025413403
-
The role of cathepsin L in malignant transformation
-
Kane SE, Gottesman MM. The role of cathepsin L in malignant transformation. Semin Cancer Biol. 1990; 1: 127-36.
-
(1990)
Semin Cancer Biol.
, vol.1
, pp. 127-136
-
-
Kane, S.E.1
Gottesman, M.M.2
-
51
-
-
75149123481
-
The anti-angiogenic activity of NSITC, a specific cathepsin L inhibitor
-
Rebbaa A, Chu F, Sudha T, et al The anti-angiogenic activity of NSITC, a specific cathepsin L inhibitor. Anticancer Res. 2009; 29: 4473-81.
-
(2009)
Anticancer Res.
, vol.29
, pp. 4473-4481
-
-
Rebbaa, A.1
Chu, F.2
Sudha, T.3
-
52
-
-
77952080571
-
Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization
-
Shimada N, Ohno-Matsui K, Iseki S, et al Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization. Am J Pathol. 2010; 176: 2571-80.
-
(2010)
Am J Pathol.
, vol.176
, pp. 2571-2580
-
-
Shimada, N.1
Ohno-Matsui, K.2
Iseki, S.3
|